Syphilitic neuroretinitis.

Abstract:

:Four patients (three men, 32, 43, and 53 years old, and one 37-year-old woman) with syphilitic neuroretinitis had cerebrospinal fluid evidence of neurosyphilis. Therapy failed in one patient given penicillin G benzathine intramuscularly and it may have failed in a second patient. Another treatment failure occurred in a patient given tetracycline orally. Intramuscular penicillin G benzathine or intramuscular penicillin G procaine in doses of less than 2.4 million units/day does not produce spirocheticidal drug levels in the cerebrospinal fluid. All four patients improved after high-dose treatment with aqueous penicillin G.

journal_name

Am J Ophthalmol

authors

Folk JC,Weingeist TA,Corbett JJ,Lobes LA,Watzke RC

doi

10.1016/0002-9394(83)90268-4

subject

Has Abstract

pub_date

1983-04-01 00:00:00

pages

480-6

issue

4

eissn

0002-9394

issn

1879-1891

pii

0002-9394(83)90268-4

journal_volume

95

pub_type

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