Abstract：
:Extraocular bacterial culture was performed in 100 patients with hypovitaminosis A xerophthalmia. There was corneal ulceration in 29 cases and corneal perforation in 22 cases. Eighty-six percent of the patients harbored frankly pathogenic bacteria (46 patients) and potentially pathogenic bacteria (40 patients). All but two patients with either cornal ulceration or perforation harbored potentially pathogenic or frankly pathogenic bacteria. Pseudomonas aeruginosa, Diplococcus pneumoniae, and Moraxella species were isolated in 37% (19 patients) of cases with corneal ulceration and perforation. I cultured P. aeruginosa from 36% (eight patients) of cases with corneal perforation. The many ocular secondary bacterial infections in the early stages of xerophthalmia seem to suggest that bacterial action plays a major role in causing the corneal ulceration and perforation in hypovitaminosis A xerophthalmia.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Valenton MJ,Tan RVdoi
10.1016/0002-9394(75)90399-2subject
Has Abstractpub_date
1975-10-01 00:00:00pages
673-7issue
4eissn
0002-9394issn
1879-1891pii
0002-9394(75)90399-2journal_volume
80pub_type
杂志文章abstract：:Topical ketoconazole (2% ointment three times per day for three weeks) markedly reduced the severity of keratitis produced with Candida albicans inoculation in the right eyes of 20 rabbits. Clinical scores of affected eyes were significantly lower in the treated eyes than in the controls, which consisted of the 20 ino...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90084-x
更新日期：1986-10-15 00:00:00
abstract：PURPOSE:To report the features of idiopathic intracranial hypertension in prepubertal children, with emphasis on presentation, treatment, and outcome. METHODS:We retrospectively reviewed the charts of all patients 11 years and younger diagnosed with idiopathic intracranial hypertension at two university-affiliated med...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00386-9
更新日期：1999-02-01 00:00:00
abstract：PURPOSE:To examine the usefulness of fluorescein angiography (FA) in identifying the macular center and diagnosis of zone in patients with retinopathy of prematurity (ROP). DESIGN:Validity and reliability analysis of diagnostic tools. METHODS:Thirty-two sets (16 color fundus photographs and 16 color fundus photograph...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.01.027
更新日期：2015-05-01 00:00:00
abstract：:Lenses removed in 408 cataract operations were cultured for bacteria. Most (78%) lenses were sterile. Of the positive cultures, 48% were positive for Staphylococcus epidermidis and 15.4% for S. aureus. These findings reflect the flora of the normal preoperative conjunctiva, and the organisms most commonly implicated i...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76805-9
更新日期：1978-08-01 00:00:00
abstract：:A 34-year-old man had a six-month history of bilateral visual loss that was secondary to cystoid macular edema, which was assumed to be secondary to neurosyphilis on the basis of cerebrospinal fluid serology, cell count, and protein. Good visual acuity was recovered with systemic corticosteroids only after they were u...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90747-5
更新日期：1979-07-01 00:00:00
abstract：:We performed 115 scleral-buckling procedures for primary rhegmatogenous retinal detachments in which the argon endolaser drained subretinal fluid. The laser was set at 0.80 to 1.25 W and 0.5 second; the endolaser probe was held adjacent to, but not touching, the choroid. The procedure was successful in 112 of 115 (97....
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73643-8
更新日期：1993-06-15 00:00:00
abstract：PURPOSE:To assess whether successful surgical intervention for intermittent exotropia, or the timing of intervention, has any effect on the development of mental illness. DESIGN:Retrospective, observational case series. METHODS:All patients (<19 years of age) diagnosed with intermittent exotropia in Olmsted County, M...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.06.008
更新日期：2014-10-01 00:00:00
abstract：:A central retinal artery occlusion occurred in the left eye of a 25-year-old woman with migraine and bilateral intrapapillary drusen. An extensive investigation failed to establish the presence of any systemic disease or vasculopathy. Eight years later she had a central retinal artery occlusion in her right eye. Optic...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90305-x
更新日期：1989-03-15 00:00:00
abstract：PURPOSE:To document a case of Candida tropicalis endophthalmitis as the only manifestation of pacemaker endocarditis. METHODS:We examined a 75-year-old man with diabetes mellitus who was initially examined for bilateral multifocal endophthalmitis complicating endocarditis 2 years after a permanent pacemaker for sick s...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70189-8
更新日期：1997-04-01 00:00:00
abstract：PURPOSE:To develop patient-derived Pediatric Eye Questionnaires (PedEyeQ) to separately assess eye-related quality of life (ER-QOL) and functional vision in children with eye conditions. DESIGN:Questionnaire development study. METHODS:A total of 444 children (0 to <18 years old), across 10 diagnostic categories, were...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2019.01.001
更新日期：2019-04-01 00:00:00
abstract：:The Prospective Evaluation of Radial Keratotomy Study is a nine-center clinical trial of a standardized technique of radial keratotomy in 435 patients who had simple myopia with a preoperative refraction between -2.00 and -8.00 diopters. We studied the stability of the refractive error during four years after surgery ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72250-0
更新日期：1991-02-15 00:00:00
abstract：:A survey in Arkansas of 14 cases of ocular injuries caused by the explosion of Class C fireworks showed significant, and possibly permanent, visual loss in five men. The most common injuries, corneal abrasion and hyphema, occurred in nine male patients with no residual ocular damage. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90621-2
更新日期：1975-03-01 00:00:00
abstract：PURPOSE:To determine the aqueous levels of vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) in patients with active polypoidal choroidal vasculopathy (PCV) and choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) and pathologic myopia. DESIGN:Pros...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2005.10.012
更新日期：2006-03-01 00:00:00
abstract：PURPOSE:To determine if a 1-day, 1-eye trial of latanoprost 0.005% was predictive of the 1-month intraocular pressure response in patients with uncontrolled open-angle glaucoma on maximally tolerated medical therapy without latanoprost. METHODS:One eye of 39 consecutive patients was enrolled in prospective trial of la...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9394(01)01253-3
更新日期：2001-12-01 00:00:00
abstract：PURPOSE:To analyze the effect of intensified topical steroid therapy after Descemet membrane endothelial keratoplasty combined with cataract surgery (triple-DMEK) on the incidence of postoperative cystoid macular edema (CME). DESIGN:Single-center comparative clinical study with historical controls. METHODS: SETTING:...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.12.008
更新日期：2016-03-01 00:00:00
abstract：:Twenty-six eyes of 25 patients with chronic open-angle glaucoma and surgical aphakia with inadequate control of intraocular pressure (IOP) despite maximal medical treatment were treated with cyclocryotherapy, according to a prospective protocol and specific technique. (Neovascular and synechial glaucoma were excluded ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)77093-x
更新日期：1978-05-01 00:00:00
abstract：PURPOSE:Longstanding corneal edema can lead to anterior stromal scarring that may limit visual acuity following Descemet stripping endothelial keratoplasty (DSEK). The ideal time to perform DSEK to prevent permanent changes is unclear. Our aim is to determine whether earlier DSEK is associated with improved visual outc...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2016.09.006
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:To evaluate qualitatively the structural characteristics and the associated features that antedate the occurrence of a disk hemorrhage in patients with glaucoma. METHODS:Retrospective observational case series. A total of 4018 pairs of stereoscopic optic disk images obtained over 15 years were reviewed. All ey...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01009-1
更新日期：2001-09-01 00:00:00
abstract：PURPOSE:To report an unusual, blinding inflicted eye injury in young children. DESIGN:Observational case report. METHODS:Retrospective study in an institutional clinical practice of two families in whom the probands had inferior half keratoconjunctivitis and additional signs of child abuse. RESULTS:Two unrelated inf...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.06.089
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:To investigate the effect of nocturnal blood pressure (BP) dips on the occurrence of optic disc hemorrhage (ODH) in normal-tension glaucoma (NTG) patients and determine whether ODH is associated with greater likelihood of visual field progression (VFP). DESIGN:Prospective case-control study. METHODS:This stud...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.01.002
更新日期：2017-04-01 00:00:00
abstract：PURPOSE:To ascertain deformation of the optic nerve head (ONH) and peripapillary tissues caused by horizontal duction. DESIGN:Prospective, experimental study. METHODS:Optical coherence tomography of the ONH region was performed in 23 eyes of 12 normal volunteers in central gaze and increasing (10, 20, and 30 degrees)...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2016.10.001
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:To compare the long-term efficacy and safety of 2 operation methods for late in-the-bag intraocular lens (IOL) dislocation. DESIGN:Prospective, randomized, parallel group surgical clinical trial. METHODS:During a 3-year period, 104 patients (104 eyes) were assigned one group for IOL repositioning by scleral s...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2019.05.030
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:To assess the potential effect of intravitreal bevacizumab (IVB) (Avastin) on retinal function and anatomic recovery in eyes with choroidal neovascularization attributable to pathological myopia (mCNV). DESIGN:Retrospective case series. METHODS:setting: Institutional. patient population: Sixty-three eyes of 6...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.07.017
更新日期：2009-01-01 00:00:00
abstract：:The medical records of 93 patients with pigmentary glaucoma and 18 patients with pigment dispersion syndrome were studied with regard to factors associated with the presence and severity of secondary glaucoma within this population. Male gender, black race, severe myopia, and Krükenberg spindles were identified as pos...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90110-4
更新日期：1989-09-15 00:00:00
abstract：PURPOSE:To evaluate the effect on peripheral visual field defects occurring after macular hole surgery of passing air that is used for fluid-air exchange through water before infusion to the eye. METHODS:We used Goldmann perimetry to measure the visual fields of patients who underwent vitrectomy to manage idiopathic f...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00287-6
更新日期：1999-01-01 00:00:00
abstract：PURPOSE:Report incidence and risk of retinal detachment (RD)after coaxial phacoemulsification in high myopic patients. DESIGN:Retrospective consecutive interventional study. METHODS: SETTING:Vissum-Instituto Oftalmologico de Alicante, Spain. PATIENT OR STUDY POPULATION: A total of 439 eyes from 274 high myopic patie...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.03.043
更新日期：2007-07-01 00:00:00
abstract：PURPOSE:To quantify, compare, and assess differences between retinal and choroidal hemodynamics in normal control subjects and patients with ocular hypertension, primary open-angle glaucoma, and normal-pressure glaucoma. METHODS:Video fluorescein angiograms were made in 20 normal subjects, 11 patients with ocular hype...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71077-3
更新日期：1997-05-01 00:00:00
abstract：:Eleven patients with intracranial malignant neoplasms underwent hyperosmotic opening of the blood-brain barrier by rapid mannitol infusion via the internal carotid or vertebral artery. Cyclophosphamide was administered intravenously preceding the mannitol infusion and methotrexate was infused after the mannitol via th...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90536-2
更新日期：1986-11-15 00:00:00
abstract：PURPOSE:To compare the surgical outcomes of ocular surface squamous neoplasia (OSSN) following wide excisional biopsy with and without primary simple limbal epithelial transplantation (p-SLET). DESIGN:Nonrandomized clinical study with historical controls. METHODS:setting: Single-institutional study. PATIENTS:Eight p...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2016.10.021
更新日期：2017-02-01 00:00:00
abstract：:Amyloid was identified by light and electron microscopy within corneal grafts of two male siblings from a family with lattice corneal dystrophy type 1. These deposits indicate a recurrent disease within the donor tissue, and we believe this reflects an infiltration of the grafts by genetically abnormal host corneal fi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(82)90251-3
更新日期：1982-10-01 00:00:00
