Abstract：
PURPOSE:To determine provider compliance with hydroxychloroquine screening following the revised recommendations published in 2011 by the American Academy of Ophthalmology. DESIGN:Evaluation of adherence to a screening protocol. METHODS:Subjects were identified with hydroxychloroquine as a medication by electronic query at a large multispecialty ophthalmic practice. Patients were excluded if patients: (1) were screened by an outside physician; (2) lacked recorded height, weight, start date, or dosing; or (3) took hydroxychloroquine for malaria prophylaxis. Screening tests were stratified by ophthalmic subspecialty. Guidelines define proper screening as 1 subjective test-Humphrey visual field (HVF), and 1 objective test-spectral-domain optical coherence tomography (SD OCT), fundus autofluorescence (FAF), or multifocal electroretinography (mfERG). Adherence to guidelines was determined by categorizing practices as: (1) "appropriate"-consistent with guidelines; (2) "underscreened"-insufficient testing; or (3) "inappropriate"-no testing. RESULTS:The study comprised 756 patients with a mean age of 56 years undergoing 1294 screening visits. Twenty-one patients received initial screenings outside the institution. Most common screening tests employed included SD OCT (56.6%), 10-2 HVF (55.0%), and Amsler grid (40.0%). Of the 735 initial screenings, 341 (46.4%) were appropriately screened, 204 (27.8%) underscreened, and 190 (25.9%) inappropriately screened. Of those who presented solely for screening (560), 307 (54.8%) were appropriately screened, 144 (25.7%) underscreened, and 109 (19.5%) inappropriately screened. CONCLUSIONS:Of patients presenting for hydroxychloroquine screening, 54.8% of patients received appropriate evaluation, indicating lack of adherence to guidelines. Overall, SD OCT and 10-2 HVF were the preferred screening modalities, with FAF and mfERG less frequently ordered.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Au A,Parikh V,Modi YS,Ehlers JP,Schachat AP,Singh RPdoi
10.1016/j.ajo.2015.06.009subject
Has Abstractpub_date
2015-09-01 00:00:00pages
561-568.e2issue
3eissn
0002-9394issn
1879-1891pii
S0002-9394(15)00362-1journal_volume
160pub_type
杂志文章abstract：PURPOSE:Descemet membrane endothelial keratoplasty is a new technique for the replacement of diseased corneal endothelium with healthy donor endothelium. During this procedure, manipulation of the donor endothelium-Descemet membrane layer within the recipient anterior chamber can be associated with loss of the correct ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.01.005
更新日期：2010-06-01 00:00:00
abstract：PURPOSE:To provide evidence that corticosteroid-induced ocular hypertension has a genetic component. DESIGN:Evidence-based perspective. METHODS:We conducted a comprehensive literature search for studies exploring genetic influences on intraocular pressure responses to corticosteroid treatment. RESULTS:Studies demons...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
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abstract：PURPOSE:To report a case of bilateral periopticoscleral hemorrhages associated with traumatic child abuse. METHODS:Postmortem gross examination and histopathologic studies of both eyes and the optic nerves of a 6-month-old infant who died from subdural hematoma. RESULTS:Gross examination and histopathologic step sect...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00392-4
更新日期：1999-04-01 00:00:00
abstract：:Seventeen patients (ten women and seven men, 23 to 72 years old) with stromal herpetic disease were treated with topical and oral acyclovir for 14 days. Of the 12 patients with disciform edema, five showed minimal improvement, four showed no change, and three showed worsening of their disease. Of the five patients wit...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90237-x
更新日期：1984-11-01 00:00:00
abstract：PURPOSE:To determine if there are variations in regional practice patterns for retinal detachment repair in the United States. DESIGN:Retrospective, noninterventional, cross-sectional study. METHODS:Year 2009 Medicare fee-for-service claims for retinal detachment repair were aggregated in 4 geographic regions and eva...
journal_title：American journal of ophthalmology
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doi：10.1016/j.ajo.2011.11.034
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:To investigate the changes in absolute neutrophil counts in patients with and without pain after verteporfin infusion. DESIGN:Experimental study. METHODS:The absolute neutrophil counts were obtained from the blood samples taken at the beginning of infusion and after the end of verteporfin infusion. RESULTS:F...
journal_title：American journal of ophthalmology
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abstract：PURPOSE:To report the sensitivity and specificity of B-scan ultrasonography to detect macular thickening. DESIGN:Observational case series. METHODS:Seventy-seven eyes of 40 consecutive patients (age range, 7-80 years) in a retinal specialty practice were examined. A single masked ultrasound operator performed B-scan ...
journal_title：American journal of ophthalmology
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更新日期：2003-07-01 00:00:00
abstract：PURPOSE:To determine whether a three-year fluocinolone acetonide sustained drug delivery system can be implanted safely at the same time that phacoemulsification and intraocular lens (IOL) implantation are performed for a visually significant cataract in eyes with uveitis. DESIGN:Retrospective, single-center case seri...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
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更新日期：2008-10-01 00:00:00
abstract：PURPOSE:To report the cases of four patients with hepatitis C virus infection who experienced clinical features that are virtually identical to Vogt-Koyanagi-Harada disease (VKH). DESIGN:Retrospective observational case series. METHODS:Medical records of patients who were referred between January and December 2003 we...
journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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doi：10.1016/s0002-9394(14)73696-7
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73813-9
更新日期：1995-01-01 00:00:00
abstract：:The technique of keratoprosthesis was used in 21 cases of severe and intractable forms of keratopathy during the past 3 1/2 years. The results in terms of visual acuity were satisfactory in more than half the cases. Significant problems that occurred after this procedure included the diagnosis and management of glauc...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1979-08-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2011.09.006
更新日期：2012-04-01 00:00:00
abstract：:We measured skin reactions serum antibody, and lymphocyte stimulation to Histoplasma antigens in a series of patients with presumed ocular histoplasmosis syndrome and in controls. The most sensitive test, lymphocyte stimulation to H. capsulatum sonicate, also correlated with severity of the disease. Lymphocyte stimula...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90069-2
更新日期：1979-03-01 00:00:00
abstract：PURPOSE:To explore the impact of intracameral air tamponade pressure and duration on graft attachment and rebubbling rates. DESIGN:A prospective, interventional, nonrandomized study. METHODS:setting: Department of Ophthalmology, Charité - Universitätsmedizin Berlin. STUDY POPULATION:One hundred seventeen patients wh...
journal_title：American journal of ophthalmology
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更新日期：2017-06-01 00:00:00
abstract：PURPOSE:To report the outcome of balloon catheter dilation of the lacrimal duct for treatment of children with persistent nasolacrimal duct obstruction after previous surgery. DESIGN:Interventional case series. METHODS:Thirty-two consecutive children with a history of persistent nasolacrimal duct obstruction followin...
journal_title：American journal of ophthalmology
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更新日期：2002-03-01 00:00:00
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1994-01-15 00:00:00
abstract：:We studied the ultrastructural characteristics of an experimental model of traction retinal detachment secondary to a penetrating eye injury in the rhesus monkey. Cells with the characteristics of myofibroblasts were present in the intravitreal fibrous tissue and in epiretinal membranes. These cells were probably deri...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75198-0
更新日期：1980-12-01 00:00:00
abstract：:A 29-year-old woman had a pigmented ciliary body mass that extended through the iris into the anterior chamber. On the basis of clinical findings and ancillary diagnostic studies, the clinical diagnosis was malignant melanoma of the ciliary body. The enucleated eye showed the tumor to be composed of cells identical to...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1980-05-01 00:00:00
abstract：:Two groups of patients, 37 with primary basal cell carcinoma of the eyelid and 16 with basal cell carcinoma of the eyelid previously treated by other physicians were reviewed. All of the tumors were excised with at least 3 to 4 mm of normal-appearing tissue at each margin of resection. All of the excised specimens wer...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90358-1
更新日期：1979-06-01 00:00:00
abstract：:Benign lateral rectus palsy developed in two adults, a 62-year-old man and a 56-year-old woman. Both were hospitalized because of headache and diplopia. Extensive laboratory and neurologic testing showed no abnormalities except leukopenia (the white blood cell count was 2,600 cells/mm3 in one patient and 3,100 cells/m...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1982-10-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.04.014
更新日期：2004-09-01 00:00:00
abstract：PURPOSE:beta-Adrenergic blocking drugs lower intraocular pressure. The question of whether these drugs also alter, either directly or indirectly, orbital hemodynamics is potentially of great importance for patients with normal-tension glaucoma who may have some degree of reversible vasospasm. METHODS:We compared the e...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1995-08-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2016-07-01 00:00:00
abstract：PURPOSE:To report two patients with severe fungal corneal ulcers who were treated successfully with topical amphotericin B ointment. METHODS:Two eyes of two patients developed corneal ulcers and hypopyon after corneal foreign body removal. Aspergillus fumigatus and Fusarium solani were isolated in Patients 1 and 2, re...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71701-5
更新日期：1997-12-01 00:00:00
abstract：PURPOSE:To report a case of chronic unilateral ptosis in a 63-year-old, otherwise healthy woman with visual restriction. METHODS:We performed a biopsy on an enlarged tarsal plate that we believed had caused ptosis. A levator aponeurotic advancement was performed subsequently. RESULTS:Histologic and ultrastructural ex...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71145-6
更新日期：1997-06-01 00:00:00
