Abstract:
PURPOSE:To report a case of bilateral periopticoscleral hemorrhages associated with traumatic child abuse. METHODS:Postmortem gross examination and histopathologic studies of both eyes and the optic nerves of a 6-month-old infant who died from subdural hematoma. RESULTS:Gross examination and histopathologic step sections disclosed bilateral intrascleral hemorrhages around both optic nerves. In addition, bilateral diffuse multilayered retinal, vitreous, and sublaminar (beneath the internal limiting membrane) hemorrhages were present. CONCLUSION:Periopticointrascleral hemorrhages are characteristic of blunt head trauma and may constitute important forensic evidence in cases of suspected child abuse.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Lin KC,Glasgow BJdoi
10.1016/s0002-9394(98)00392-4subject
Has Abstractpub_date
1999-04-01 00:00:00pages
473-5issue
4eissn
0002-9394issn
1879-1891pii
S0002939498003924journal_volume
127pub_type
杂志文章abstract:PURPOSE:To report rapidly progressive rhino-orbitocerebral mucormycosis in a 47-year-old woman with both diabetes mellitus and the acquired immunodeficiency syndrome (AIDS). METHOD:Case report including postmortem examination of the eyes, orbit, and brain of a patient with rhino-orbitocerebral mucormycosis, diabetes m...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70392-7
更新日期:1996-12-01 00:00:00
abstract:PURPOSE:To compare race-related differences in estimated rate of change of Bruch's membrane opening-minimum rim width (BMO-MRW) and circumpapillary retinal nerve fiber layer thickness (RNFLT) in healthy, glaucoma suspect, and glaucoma eyes of individuals of European (ED) and African descent (AD). DESIGN:Prospective co...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.08.050
更新日期:2018-12-01 00:00:00
abstract::We obtained serial electroretinograms in four patients aged between 6 months and 5 years with Alström's syndrome and studied the early stages of the severe retinopathy that is characteristic of that disease. The weak electroretinographic signals found at age 6 months demonstrate a severe early cone dysfunction; one ye...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71466-7
更新日期:1993-05-15 00:00:00
abstract:PURPOSE:To evaluate the disease extent on ultra-widefield fundus autofluorescence (UWF-FAF) in patients with ABCA4 Stargardt disease (STGD) and correlate these data with functional outcome measures. DESIGN:Retrospective cross-sectional study. METHODS:Setting: Kellogg Eye Center, University of Michigan. STUDY POPULAT...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.10.006
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:To determine the ability to detect normal vitreous structure, evolving posterior vitreous detachment (PVD), and related vitreoretinal changes with combined spectral-domain optical coherence tomography (SD-OCT) and scanning laser ophthalmoscopy (SLO). DESIGN:Observational cross-sectional study. METHODS:Simulta...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.11.016
更新日期:2010-04-01 00:00:00
abstract::To study the retinal surface in the human eye in normal and diseased states we used laser scanning tomography. The confocal arrangement of the laser tomographic scanner permits examination of retinal topography in the axis perpendicular to the retinal surface. The eyes examined with the laser tomographic scanner inclu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(89)90118-9
更新日期:1989-09-15 00:00:00
abstract::We compared endothelial preservation of paired corneas by scanning electron microscopy after storage in McCarey-Kaufman medium for two or three days to 2.5% chondroitin sulfate (K-Sol) for seven or ten days. One cornea from each of ten pairs of eyes was placed in McCarey-Kaufman medium and the opposite cornea was plac...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74106-6
更新日期:1987-11-15 00:00:00
abstract:PURPOSE:To determine the relationship between eyelid pressure during blinking and the fluorescein staining of the cornea and conjunctiva in dry eye patients. DESIGN:Cross-sectional prospective study. METHODS:The pressure of the upper and lower eyelids was measured with a specially designed blepahro-tensiometer in 130...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2015.06.028
更新日期:2015-10-01 00:00:00
abstract:PURPOSE/METHODS:Orthoclone OKT3 is a monoclonal murine IgG immunoglobulin used to treat acute cellular rejection of allografted organs. Aseptic meningitis and meningoencephalopathy are known adverse side effects from the drug. OKT3 caused additional ophthalmologic and neurologic complications in an 18-year-old woman wh...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70236-3
更新日期:1995-05-01 00:00:00
abstract:PURPOSE:To provide evidence-based recommendations for diabetic macular edema (DME) management based on updated information from publications on DME treatment modalities. DESIGN:Perspective. METHODS:A literature search for "diabetic macular edema" or "diabetic maculopathy" was performed using the PubMed, Cochrane Libr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,实务指引
doi:10.1016/j.ajo.2013.11.012
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:An association of glaucoma and sleep apnea syndrome (SAS) has been widely reported. We investigated the largest group of patients with SAS thus far to determine the prevalence of glaucoma among these patients. DESIGN:Cross-sectional study. METHODS:An institutional study. STUDY POPULATION:A total of 228 patie...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00709-8
更新日期:2003-12-01 00:00:00
abstract:PURPOSE:To report the efficacy and safety of outpatient fluid-gas exchange for open macular hole after primary vitrectomy. DESIGN:Retrospective interventional case series. METHODS:setting: Institutional. patients: Thirty-six patients with primary failed closure or reopened holes after primary vitrectomy. intervention...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2013.03.031
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:In its most severe form, retinopathy of prematurity (ROP) is located in posterior retina and affects the smallest, most premature infants. We hypothesize that, depending on whether vasculogenesis (de novo formation of new vessels by transformation of vascular precursor cells (VPCs)) or angiogenesis (budding fro...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.02.018
更新日期:2006-07-01 00:00:00
abstract:PURPOSE:To identify associations between severity of sickle cell retinopathy (SCR) and other clinical, laboratory, or treatment factors relevant to sickle cell disease (SCD). DESIGN:Retrospective cohort study. METHODS:We investigated clinical, laboratory, and demographic associations with the severity of SCR in 296 p...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.09.025
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To document and study the relationship between perimetric sensitivity and retinal thickness at the foveal and parafoveal points in eyes with macular edema associated with branch retinal vein occlusion. METHODS:A prospective study was performed using the central 10-2 Humphrey perimetry program and optical coher...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00722-4
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:To describe the incidence rates of visual loss and ocular complications in patients with retinal vasculitis (RV). DESIGN:Retrospective cohort study. METHODS:Clinical data were collected for 96 patients (175 eyes) diagnosed with RV from 2003 to 2013. Main outcome measures included rates of visual loss and ocul...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.05.007
更新日期:2017-07-01 00:00:00
abstract:PURPOSE:To compare the clinical features and antibiotic susceptibility of ocular methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA). DESIGN:Cross-sectional study. METHODS:The Proctor clinical laboratory database was reviewed to identify all ocular isolates of S. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.03.032
更新日期:2007-08-01 00:00:00
abstract:PURPOSE:To show that extending Doppler imaging into the high-frequency domain could allow detection and characterization of blood flow in small arterioles and capillaries. METHODS:A 40-MHz continuous wave Doppler system and a 60-MHz pulsed-wave Doppler system were constructed, tested, and used to examine the ciliary b...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00122-6
更新日期:1998-10-01 00:00:00
abstract:PURPOSE:To investigate the potential influences that affect visual acuity (VA) outcome in a clinic-based cohort of age-related macular degeneration (AMD) patients undergoing anti-vascular endothelial growth factor (anti-VEGF) treatment for choroidal neovascularization. DESIGN:Prospective interventional case series. M...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2011.09.013
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:To evaluate macular retinal ganglion cell thickness in patients with neovascular age-related macular degeneration (AMD) and intravitreal anti-vascular endothelial growth factor (VEGF) therapy. DESIGN:Retrospective case series with fellow-eye comparison. METHODS:Patients with continuous unilateral anti-VEGF tr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.04.003
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To implant foldable posterior chamber intraocular lenses in the absence of capsular and zonular support. METHODS:Case reports. In two patients, two eyes with aphakia, lack of capsular or zonular support, and contact lens intolerance underwent the implantation of a silicone and an acrylic foldable posterior cha...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00297-9
更新日期:1999-02-01 00:00:00
abstract:PURPOSE:To evaluate the ocular hypotensive effect and safety of carteolol hydrochloride 1% vs timolol maleate 0.5%. METHODS:One hundred seventy-six patients with ocular hypertension or primary open-angle glaucoma were randomly assigned to receive either carteolol 1% twice a day or timolol maleate 0.5% solution twice a...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0002-9394(14)70865-7
更新日期:1997-10-01 00:00:00
abstract::Clinic patients and students were given several regular drops of commercial 10% phenylephrine HCl, and 1.0% cyclopentolate HCl or 1.0% tropicamide HCl. The drops were given three times at five-minute intervals. Mydriasis and cycloplegia were determined and compared with the results obtained by using one of the followi...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-9394(78)90129-0
更新日期:1978-12-01 00:00:00
abstract:PURPOSE:To explore the possible involvement of adrenomedullin in the pathophysiology of intraocular and orbital tumors. METHODS:Competitive reverse transcription-polymerase chain reaction was used to determine adrenomedullin mRNA levels in the tissues from 40 consecutive patients (40 eyes) undergoing vitrectomy, orbit...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00442-0
更新日期:2000-04-01 00:00:00
abstract:PURPOSE:To report central serous chorioretinopathy associated with excessive use of compounds with sympathomimetic activity. DESIGN:Observational case series. METHODS:Four patients presented with clinical and fluorescein angiographic evidence of central serous chorioretinopathy. All patients expressed a concomitant p...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00076-x
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:To assesses the role of photodynamic therapy (PDT) with verteporfin in young patients with choroidal neovascularization (CNV) secondary to traumatic choroidal rupture. DESIGN:Retrospective case series. METHODS:Of 26 eyes with traumatic choroidal rupture followed since 1984 at the retina service of university ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.10.009
更新日期:2005-04-01 00:00:00
abstract::In 29 experiments, vascular autologous retina from the contralateral rabbit eye was implanted into corneal pockets in New Zealand white rabbits. The implants induced a neovascular growth of limbal vessels that anastomosed with the vessels of the implant in 15 of the cases. Implantation of vascular autologous iris, cho...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90116-6
更新日期:1980-02-01 00:00:00
abstract:PURPOSE:To describe the ocular complications of smallpox vaccination and to discuss potential therapeutic options. DESIGN:Review of pertinent medical literature and recent treatment recommendations of the Centers for Disease Control and Prevention. RESULTS:After immunization against smallpox, vaccinia infection of th...
journal_title:American journal of ophthalmology
pub_type: 历史文章,杂志文章,评审
doi:10.1016/s0002-9394(03)00293-9
更新日期:2003-08-01 00:00:00
abstract:PURPOSE:In previous studies of fungal keratitis (FK) from temperate countries, yeasts were the predominant isolates, with ocular surface disease (OSD) being the leading risk factor. Since the 2005-2006 outbreak of contact lens (CL)-associated Fusarium keratitis, there may have been a rise in CL-associated filamentary F...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.05.021
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:To compare functional results after surgery for macular pucker either with or without indocyanine-green staining of the internal limiting membrane (ILM) and to evaluate the ultrastructure of the tissue removed. DESIGN:Retrospective analysis of two successive, consecutive, interventional case series. METHODS:F...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01969-4
更新日期:2003-03-01 00:00:00