Abstract:
PURPOSE:To describe the incidence rates of visual loss and ocular complications in patients with retinal vasculitis (RV). DESIGN:Retrospective cohort study. METHODS:Clinical data were collected for 96 patients (175 eyes) diagnosed with RV from 2003 to 2013. Main outcome measures included rates of visual loss and ocular complications. Comparison of outcomes in patients with a relapsing vs nonrelapsing disease also were analyzed. RESULTS:Over a median follow-up of 44 months (range: 1-153 months), the rate of visual loss to 20/50 or worse was 0.13 per eye-year (/EY, 95% confidence interval [CI], 0.09/EY to 0.18/EY) and to 20/200 or worse was 0.06/EY (95% CI, 0.04/EY to 0.08/EY). The most common complications were cataract (0.31/EY), epiretinal membrane (0.16/EY), and recurrent macular edema (0.09/EY). Patients with a relapsing course (median number of relapses = 1, range: 1-6) appeared to have greater risk for visual loss to 20/50 (odds ratio [OR] = 2.07; 95% CI, 0.88-4.90, P = .09) and 20/200 or worse (OR = 2.49; 95% CI, 0.98-6.30, P = .05). Immunosuppressive drug therapy lowered the risk of visual loss, independent of relapsing disease course (OR = 0.79; 95% CI, 0.66-0.94, P = .01 and OR = 0.73; 95% CI, 0.57-0.93, P = .01 for the 20/50 or worse and 20/200 or worse thresholds, respectively). CONCLUSIONS:Rates of visual loss and complications among patients with RV were similar to reported rates in noninfectious uveitides. Treatment with immunosuppressive drugs lowered the risk of visual loss. A relapsing course suggested an increased risk for visual loss but was not statistically significant, perhaps owing to low numbers of recurrences.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Mir TA,Reddy AK,Burkholder BM,Walsh J,Shifera AS,Khan IR,Thorne JEdoi
10.1016/j.ajo.2017.05.007subject
Has Abstractpub_date
2017-07-01 00:00:00pages
171-178eissn
0002-9394issn
1879-1891pii
S0002-9394(17)30204-0journal_volume
179pub_type
杂志文章abstract::I used a soft-tip suction needle during a vitrectomy procedure to life glass foreign bodies away from the retina so they could be more easily and safely grasped with foreign-body extraction forceps. The use of the instrument reduces the chance of inadvertent scraping of glass fragments or instruments against the retin...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:American journal of ophthalmology
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journal_title:American journal of ophthalmology
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journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:American journal of ophthalmology
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更新日期:2019-11-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1997-01-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
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更新日期:2019-06-01 00:00:00
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