Abstract:
:We studied two cases of bilateral visual loss secondary to an optic neuropathy in patients with cryptococcal meningitis. In both cases a history of visual loss after the onset of an episode of cryptococcal meningitis was elicited. Visual fields were consistent with optic nerve disease. The patients' visual loss appeared to be the result of perineuritic adhesive arachnoiditis. Although no surgical interventions were carried out in our patients, medical or surgical intervention may be useful to prevent or relieve constrictive arachnoiditis and preserve vision in selected patients.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Lipson BK,Freeman WR,Beniz J,Goldbaum MH,Hesselink JR,Weinreb RN,Sadun AAdoi
10.1016/0002-9394(89)90498-4subject
Has Abstractpub_date
1989-05-15 00:00:00pages
523-7issue
5eissn
0002-9394issn
1879-1891pii
0002-9394(89)90498-4journal_volume
107pub_type
杂志文章abstract::A 14-year-old boy was stabbed above the left eye and had subsequent loss of both retinal and choroidal perfusion to the posterior segment. Ophthalmoscopic examination ten days after the injury disclosed intense nerve fiber layer edema, most prominent in the posterior pole, and absence of a cherry-red spot. Intravenous...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90666-4
更新日期:1979-10-01 00:00:00
abstract:PURPOSE:To determine the aqueous levels of vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) in patients with active polypoidal choroidal vasculopathy (PCV) and choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) and pathologic myopia. DESIGN:Pros...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2005.10.012
更新日期:2006-03-01 00:00:00
abstract::A 3 1/2-month-old boy with the cerebro-oculo-facio-skeletal syndrome had low birth weight, microcephaly, microphthalmia, cataracts, blepharophimosis, high nasal bridge, micrognathia, kyphosis, rocker-bottom feet, and a longitudinal foot groove. The product of a consanguineous parentage, he showed marked developmental ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90127-0
更新日期:1980-02-01 00:00:00
abstract::We believe axoplasmic transport alteration is the anatomic substrate for formation of drusen of the optic disk. In familial cases the cause of axoplasmic transport alteration may be related to the presence of a genetically determined, small, crowded optic nerve head. We believe these congenitally elevated nerve heads ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)76658-9
更新日期:1978-01-01 00:00:00
abstract:PURPOSE:To determine if a positive response of macular cysts to treatment with dorzolamide eye drops in patients with juvenile X-linked retinoschisis (XLRS) can occur with mutations that result in different types of retinoschisin protein dysfunction. DESIGN:Retrospective case series. METHODS:Thirteen eyes of seven pa...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2008.07.041
更新日期:2009-01-01 00:00:00
abstract::Twenty-two of 23 obligate female carriers in nine families with known X-chromosome-linked retinitis pigmentosa were detected on the basis of abnormal full-field electroretinograms (ERGs). Only 14 of these carriers had fundus findings characteristic of the carrier state. Electroretinograms of carriers were either reduc...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90231-9
更新日期:1979-04-01 00:00:00
abstract::Normal volunteers used 1, 2, and 4% pilocarpine eyedrops, three times daily, or ocular therapeutic systems placed in the conjunctival cul-de-sac to control intraocular pressure. The systems continuously release 20 and 40 mug/hour of pilocarpine for one week. Although the amount of drug delivered to the eye from the o...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/0002-9394(75)90404-3
更新日期:1975-10-01 00:00:00
abstract:PURPOSE:To use the capillary-free zone along retinal arteries, a physiologic area of superficial avascularization, as an anatomic paradigm to investigate the reliability of optical coherence tomography angiography (OCTA) for visualizing the deep retinal circulation. DESIGN:Validity analysis and laboratory investigatio...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.02.007
更新日期:2018-05-01 00:00:00
abstract::Long-term medical therapy and laser trabeculoplasty have been implicated as risk factors in the outcome of glaucoma filtration surgery. A retrospective analysis was performed of patients undergoing primary trabeculectomy during three key periods: before use of beta-blockers and laser trabeculoplasty (1975 and 1976), a...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73068-5
更新日期:1994-02-15 00:00:00
abstract:PURPOSE:To report an HIV-negative lymphoma patient who developed progressive outer retinal necrosis syndrome and who had a good visual outcome after treatment with two-drug antiviral therapy and intravenous immunoglobulin. METHODS:Case report. RESULTS:A 43-year-old man with small lymphocytic lymphoma was diagnosed wi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00951-x
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:To report an unusual, blinding inflicted eye injury in young children. DESIGN:Observational case report. METHODS:Retrospective study in an institutional clinical practice of two families in whom the probands had inferior half keratoconjunctivitis and additional signs of child abuse. RESULTS:Two unrelated inf...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.06.089
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To report a case of chronic unilateral ptosis in a 63-year-old, otherwise healthy woman with visual restriction. METHODS:We performed a biopsy on an enlarged tarsal plate that we believed had caused ptosis. A levator aponeurotic advancement was performed subsequently. RESULTS:Histologic and ultrastructural ex...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71145-6
更新日期:1997-06-01 00:00:00
abstract:PURPOSE:To perform a reference case, cost-utility analysis of epiretinal membrane (ERM) surgery using current literature on outcomes and complications. DESIGN:Computer-based, value-based medicine analysis. METHODS:Decision analyses were performed under two scenarios: ERM surgery in better-seeing eye and ERM surgery i...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.12.037
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:To determine the frequency of ocular adverse effects associated with vemurafenib (PLX4032) treatment for metastatic cutaneous melanoma. DESIGN:Retrospective review of the clinical study reports from the clinical pharmacology, phase 1, phase 2, and phase 3 trials of vemurafenib. METHODS:The vemurafenib clinica...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2014.07.003
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:To evaluate the relationship between subjective symptoms and clinical signs in dry eye disease (DED) in office workers using visual display terminals (VDTs). DESIGN:Cross-sectional study. METHODS:This study involved 672 Japanese young and middle-aged office workers who use VDTs. The subjects completed questio...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2014.12.019
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:To apply in vivo corneal confocal microscopy (IVCM) to study the pathogenesis of keratitis (keratoendotheliitis) fugax hereditaria, an autosomal dominant cryopyrin-associated periodic keratitis, associated with the c.61G>C pathogenic variant in the NLRP3 gene, in its acute and chronic phase, and to report histo...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.02.002
更新日期:2020-05-01 00:00:00
abstract::We performed serial slit-lamp examinations and topography analysis on a patient whose initial topographic map suggested a diagnosis of keratoconus to us but which others interpreted as normal topography. Topography analysis documented cone progression during a two-year period. The initial map showed a cone apex power ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)76210-5
更新日期:1991-07-15 00:00:00
abstract:PURPOSE:To determine the regional differences in the test-retest variability of topographic measurements of the optic nerve head obtained with a confocal scanning laser retina tomograph. METHODS:Three 10-degree topographic images centered on the optic disk of 20 individuals (20 eyes), five normal subjects, seven glauc...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72656-x
更新日期:1995-10-01 00:00:00
abstract::Digital fundus angiography has advantages over conventional photography. However, digital angiography as it is normally performed, provides no stereoscopic information. Because stereoscopic data can be crucial in the evaluation of conditions such as age-related macular degeneration, we developed methods to record ster...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71409-6
更新日期:1993-10-15 00:00:00
abstract::Four patients, two men 25 and 43 years old and two women 20 and 40 years old, had complete monocular temporal hemianopsias, suggesting that it may be a more common functional deficit than has been recognized. The initial symptoms were visual loss and headache, and eye pain also occurred. Correct diagnosis is possible ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(86)90600-8
更新日期:1986-02-15 00:00:00
abstract:PURPOSE:To report a case of small cell carcinoma of the thymus metastatic to the orbit. METHODS:At age 37 years, a man who had been previously diagnosed and treated for small cell carcinoma of the thymus was initially examined for vertical diplopia and left proptosis. Computed tomographic scan disclosed a soft tissue ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70836-0
更新日期:1997-09-01 00:00:00
abstract:PURPOSE:Distance stereoacuity is used to monitor deterioration of intermittent exotropia (IXT), but variability of stereoacuity has not been studied rigorously. The purpose of this study was to assess the variability of stereoacuity over one day in children with IXT. DESIGN:Prospective cohort study. METHODS:Twelve ch...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.10.028
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:To investigate the characteristics, mergers, and risk factors of different types of myopic maculopathy (MM) in a highly myopic population. DESIGN:Population-based, cross-sectional study. METHODS:A total of 1086 eyes (762 patients) were enrolled. Each participant underwent detailed ocular examinations. Combini...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.07.010
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To describe a patient with resolved hypotony maculopathy with a persistent retinal fold (despite normalization of intraocular pressure [IOP]) who underwent successful surgical intervention by vitrectomy, internal limiting membrane peel, and gas tamponade. DESIGN:Interventional case report. METHODS:A 55-year-o...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.03.024
更新日期:2004-09-01 00:00:00
abstract:PURPOSE:To correlate in vivo confocal microscopy morphologic features (IVCM-MF) and Acanthamoeba cyst density (ACD) with final best-corrected visual acuity (BCVA) in Acanthamoeba keratitis (AK). DESIGN:Retrospective cohort study. METHODS:Patient demographics, treatment outcome, and corresponding IVCM-MF performed at ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.03.048
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To determine the feasibility of using a modified femtosecond laser to perform penetrating corneal resections. DESIGN:Controlled laboratory study. METHODS:Fourteen corneoscleral rims were mounted on an artificial anterior chamber. Eight underwent traditional penetrating keratoplasty (PKP) and six underwent "to...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.11.043
更新日期:2007-04-01 00:00:00
abstract::Forty-three patients who initially presented with Krikenberg's spindles but with no glaucomatous field defects were observed for an average of 5.8 years in an attempt to evaluate the prognostic implication of spindle presence. Twenty-two of the patients had been followed for a minimum of five years. Analysis of the st...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90075-6
更新日期:1975-02-01 00:00:00
abstract:PURPOSE:To prospectively compare the safety and efficacy of deep lamellar keratoplasty (DLKP) and penetrating keratoplasty (PKP). DESIGN:Prospective, randomized clinical trial. METHODS:Consecutive 26 eyes of 24 patients who had stromal opacity without endothelial abnormalities were randomly assigned to either PKP or ...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-9394(02)01523-4
更新日期:2002-08-01 00:00:00
abstract:PURPOSE:Wavelength dependence of diffractive intraocular lenses (IOLs) was recognized in vitro but not yet assessed in vivo. By examining pseudophakic patients who had extended-depth-of-focus diffractive implants, this spectral effect on their vision was measured clinically and the lens was tested in vitro. DESIGN:Cro...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.07.001
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To evaluate the specificity of current definitions used to identify progressive change of the average peripapillary retinal nerve fiber layer (RNFL) thickness measurements obtained on optical coherence tomography (OCT) imaging. DESIGN:Prospective observational cohort study. METHODS:Setting: University of Cali...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.06.017
更新日期:2017-09-01 00:00:00