Abstract:
PURPOSE:To report an HIV-negative lymphoma patient who developed progressive outer retinal necrosis syndrome and who had a good visual outcome after treatment with two-drug antiviral therapy and intravenous immunoglobulin. METHODS:Case report. RESULTS:A 43-year-old man with small lymphocytic lymphoma was diagnosed with progressive outer retinal necrosis in his left eye. Treatment was initiated with intravenous foscarnet and ganciclovir as well as intravenous gammaglobulin at a dose of 0.5 gm/kg per day for 5 days. On the second hospital day he was started on decadron 4 mg orally four times daily. No further posterior retinitis progression was observed despite severe immunosuppression. Visual acuity remained stable at 20/30 with 10 months' follow-up. CONCLUSIONS:The benefit of using gammaglobulin in progressive outer retinal necrosis is unknown. Given the rapid improvement seen in this patient's retinitis, it may be reasonable to consider the use of gammaglobulin in other cases of infectious retinitis in immunocompromised patients.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Foster RE,Petersen MR,Neuss MN,Osher RHdoi
10.1016/s0002-9394(00)00951-xsubject
Has Abstractpub_date
2001-07-01 00:00:00pages
117-20issue
1eissn
0002-9394issn
1879-1891pii
S000293940000951Xjournal_volume
132pub_type
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