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Resolution of pityriasis rubra pilaris-induced cicatricial ectropion with systemic low-dose methotrexate.

Abstract：

PURPOSE:To report a case of pityriasis rubra pilaris (PRP)-induced bilateral lower eyelid cicatricial ectropion that resolved with systemic low-dose methotrexate. DESIGN:Observational case report. METHODS:A retrospective case review of a patient with cicatricial ectropion caused by PRP. RESULTS:A 82-year-old female presented with bilateral lower eyelid cicatricial ectropion secondary to PRP. The patient did not systemically respond to conventional oral retinoid therapy. She was treated with low-dose methotrexate and experienced dramatic resolution of her signs and symptoms, including complete resolution of her bilateral cicatricial ectropion. CONCLUSION:Systemic treatment of PRP with low-dose methotrexate may result in successful treatment of cicatricial ectropion without surgery.

journal_name

Am J Ophthalmol

journal_title

American journal of ophthalmology

authors

Durairaj VD,Horsley MB

doi

10.1016/j.ajo.2006.11.038

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

709-10

issue

4

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(06)01324-9

journal_volume

143

pub_type

杂志文章

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