Abstract：
PURPOSE:To perform a reference case, cost-utility analysis of epiretinal membrane (ERM) surgery using current literature on outcomes and complications. DESIGN:Computer-based, value-based medicine analysis. METHODS:Decision analyses were performed under two scenarios: ERM surgery in better-seeing eye and ERM surgery in worse-seeing eye. The models applied long-term published data primarily from the Blue Mountains Eye Study and the Beaver Dam Eye Study. Visual acuity and major complications were derived from 25-gauge pars plana vitrectomy studies. Patient-based, time trade-off utility values, Markov modeling, sensitivity analysis, and net present value adjustments were used in the design and calculation of results. Main outcome measures included the number of discounted quality-adjusted-life-years (QALYs) gained and dollars spent per QALY gained. RESULTS:ERM surgery in the better-seeing eye compared with observation resulted in a mean gain of 0.755 discounted QALYs (3% annual rate) per patient treated. This model resulted in $4,680 per QALY for this procedure. When sensitivity analysis was performed, utility values varied from $6,245 to $3,746/QALY gained, medical costs varied from $3,510 to $5,850/QALY gained, and ERM recurrence rate increased to $5,524/QALY. ERM surgery in the worse-seeing eye compared with observation resulted in a mean gain of 0.27 discounted QALYs per patient treated. The $/QALY was $16,146 with a range of $20,183 to $12,110 based on sensitivity analyses. Utility values ranged from $21,520 to $12,916/QALY and ERM recurrence rate increased to $16,846/QALY based on sensitivity analysis. CONCLUSIONS:ERM surgery is a very cost-effective procedure when compared with other interventions across medical subspecialties.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Gupta OP,Brown GC,Brown MMdoi
10.1016/j.ajo.2007.12.037subject
Has Abstractpub_date
2008-05-01 00:00:00pages
923-8issue
5eissn
0002-9394issn
1879-1891pii
S0002-9394(08)00017-2journal_volume
145pub_type
杂志文章abstract：:We used narrow-band (540-nm) green-light stereoscopic fundus photography to study the surface details of the peripapillary retina in 14 patients. Each photograph was divided into four areas; the papillomacular bundle, the upper arcuate bundle, the lower arcuate bundle, and the nasal sectorial fibers. We scored each ar...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(81)90011-8
更新日期：1981-06-01 00:00:00
abstract：PURPOSE:To compare the long-term surgical outcomes of augmented bilateral lateral rectus (LR) recession with original surgery. DESIGN:Retrospective, nonrandomized clinical study. METHODS:A total of 447 children with ≤35 prism diopters (PD) of basic and divergence excess-type intermittent exotropia, who underwent orig...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.12.003
更新日期：2016-03-01 00:00:00
abstract：PURPOSE:To evaluate the effectiveness of an orbital tissue expander designed to stimulate orbital bone growth in an anophthalmic socket. DESIGN:Retrospective, noncomparative, interventional case series. METHODS: SETTINGS:Institutional. STUDY POPULATION:Nine consecutive patients with unilateral congenital anophthalm...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.09.009
更新日期：2011-03-01 00:00:00
abstract：:A 13-year-old boy developed an osteogenic sarcoma of the right humerus ten years after treatment for bilateral retinoblastoma. The bilateral retinoblastoma has been managed with enucleation of one eye and successful treatment of the solitary tumor in the other eye with a single application of a local 10-mm round cobal...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74919-0
更新日期：1980-09-01 00:00:00
abstract：:In human and primate eyes treated with cyclocryotherapy, the epithelial and capillary elements of the ciliary processes were destroyed and replaced by fibroblast-like cells. The trabecular mesh-work and Schlemm's canal were histologically affected by cyclocryotherapy. Damage to the angle structures impaired aqueous ou...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(76)90009-x
更新日期：1976-11-01 00:00:00
abstract：PURPOSE:The aim of this study is to investigate temporal trends in multifocal ERG (mfERG) parameters and analyze their relationships with anatomic and functional markers in patients with birdshot chorioretinopathy (BSCR). DESIGN:Prospective observational case series. METHODS:Sixteen BSCR patients were include and und...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.11.022
更新日期：2019-04-01 00:00:00
abstract：:We reviewed the records of 78 patients who underwent 128 surgical procedures for congenital or infantile cataracts before age 30 months for the type and frequency of postoperative complications. The surgeries included 92 limbal lensectomies and anterior vitrectomies, 13 pars plicata lensectomies, 20 aspirations, and t...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/0002-9394(89)90007-x
更新日期：1989-08-15 00:00:00
abstract：PURPOSE:To report a minimally symptomatic patient with bilateral carcinoid tumors metastatic to the choroid who was followed up for 42 months without any treatment. METHOD:Case report. RESULTS:A 54-year-old white man with a history of bronchial carcinoid tumor had bilateral multiple carcinoid tumors metastatic to the...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00053-1
更新日期：1998-06-01 00:00:00
abstract：:Two of six patients (four women and two men ranging in age from 51 to 90 years) with bilateral senile iridoschisis also had secondary unilateral narrow angle or angle-closure glaucoma. All six patients had splitting of the iris stroma inferiorly. Histopathologic studies disclosed marked iris stromal atrophy without ev...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(83)90335-5
更新日期：1983-01-01 00:00:00
abstract：PURPOSE:To analyze the biological stability of autologous serum eyedrops after lyophilization. DESIGN:Prospective, comparative experimental study. METHODS:This was a comparative study with serum obtained from 12 healthy volunteers. The concentrations of different epitheliotropic factors (eg, transforming growth facto...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.01.027
更新日期：2020-05-01 00:00:00
abstract：PURPOSE:To evaluate a new computerized segmentation technique for the quantification of intraretinal and subretinal fluid in spectral-domain optical coherence tomography (SD OCT) images of the retina. DESIGN:Prospective, cross-sectional study. METHODS:Thirty-seven B-scan images of 37 patients with exudative age-relat...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2012.07.030
更新日期：2013-02-01 00:00:00
abstract：PURPOSE:To report a case of pityriasis rubra pilaris (PRP)-induced bilateral lower eyelid cicatricial ectropion that resolved with systemic low-dose methotrexate. DESIGN:Observational case report. METHODS:A retrospective case review of a patient with cicatricial ectropion caused by PRP. RESULTS:A 82-year-old female ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.11.038
更新日期：2007-04-01 00:00:00
abstract：PURPOSE:To determine with electronic monitoring an objective measurement of adherence in two populations of subjects: those using once-daily prostaglandin analogs as sole ocular hypotensive therapy (one-drug group) and those requiring an adjunctive medicine to the prostaglandin analog (two-drug group). DESIGN:Single-s...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.06.012
更新日期：2007-10-01 00:00:00
abstract：:Digital A-scan ultrasonography provided a digital display of intraocular distances with an overall accuracy of 0.05 mm. Since the control setting was easy and calibration was unnecessary, the time of measurement is reduced and hence the apparatus is useful in clinical practice. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(77)90628-6
更新日期：1977-02-01 00:00:00
abstract：PURPOSE:To determine the prognostic factors of long-term visual outcome in birdshot retinochoroidopathy (BRC). METHODS:Design: Retrospective case series. Study Population: Successive HLA-A29+ BRC patients whose latest visit was between May and August 2013 at a single tertiary center (Pitié-Salpétrière Hospital, Paris)...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2016.08.007
更新日期：2016-10-01 00:00:00
abstract：PURPOSE:To evaluate the potential of Histoplasma capsulatum to cause optic neuritis in the setting of the acquired immunodeficiency syndrome (AIDS). METHODS:We examined a 35-year-old man with a history of AIDS and disseminated histoplasmosis who developed a unilateral progressive optic neuritis of enigmatic origin. An...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70285-5
更新日期：1996-03-01 00:00:00
abstract：PURPOSE:To investigate the frequency and types of systemic findings in patients with apparently isolated uveal coloboma. DESIGN:Cross-sectional observational study. METHODS:setting: Single-center ophthalmic genetics clinic. study population: Ninety-nine patients with uveal coloboma seen at the National Eye Institute....
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.06.037
更新日期：2013-12-01 00:00:00
abstract：:A 20-year-old woman, treated with cryopexy and xenon- and argon-laser photocoagulation for Leber's miliary aneurysms in her right eye, suffered from repeated epistaxis. She underwent an endoscopy that showed an unusual number of telangiectatic veins. Laboratory results and routine physical and neurologic examinations ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90456-0
更新日期：1975-01-01 00:00:00
abstract：:We studied 216 eyes of 160 patients who underwent combined phacoemulsification and posterior chamber intraocular lens implantation with trabeculectomy. The mean follow-up was 18.7 months, with a minimum follow-up of six months. To assess the safety and efficacy of a recently developed 3-mm incision procedure with fold...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72258-5
更新日期：1991-02-15 00:00:00
abstract：PURPOSE:To describe the clinical presentation and course of Whipple disease in an adult. METHODS:A 34-year-old man with phthisis bulbi in the right eye secondary to uveitis-induced neovascular glaucoma presented with severe acute posterior uveitis in the left eye. He underwent esophagogastroduodenoscopy and jejunal bi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00084-1
更新日期：1998-07-01 00:00:00
abstract：PURPOSE:To report the use of intravitreal injection of triamcinolone acetonide during the acute phase of Vogt-Koyanagi-Harada disease. DESIGN:Prospective interventional case series. METHODS:Three eyes from two patients at the acute phase of Vogt-Koyanagi-Harada disease with serous retinal detachments were treated wit...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2003.08.035
更新日期：2004-03-01 00:00:00
abstract：:We followed up 32 eyes of 32 patients with early glaucoma (22 with capsular glaucoma and ten with simple glaucoma) who received laser trabeculoplasty as a primary therapy. These eyes were compared with a matched control group of 32 eyes treated with medication initially. The success rate (intraocular pressure below 22...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(87)90220-0
更新日期：1987-10-15 00:00:00
abstract：PURPOSE:To report a case of bilateral periopticoscleral hemorrhages associated with traumatic child abuse. METHODS:Postmortem gross examination and histopathologic studies of both eyes and the optic nerves of a 6-month-old infant who died from subdural hematoma. RESULTS:Gross examination and histopathologic step sect...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00392-4
更新日期：1999-04-01 00:00:00
abstract：PURPOSE:Cooling can reduce clinical symptoms and pain caused by traumatic swelling or fracture of extremities. We obtained subjective and objective measures of the effects of cooling of the eyes after cataract surgery. METHODS:Twenty patients with bilateral cataracts were enrolled in this study. For each patient, an i...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71171-7
更新日期：1995-03-01 00:00:00
abstract：:Photic retinopathy was produced in two patients after a 60-minute exposure to light from an operating room microscope (Zeiss OpMi 6). The first patient had a blind eye with clear (phakic) media and a normal-appearing retina. A 60-minute exposure produced an oval gray lesion in the posterior pole at the level of the pi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90946-3
更新日期：1986-05-15 00:00:00
abstract：:We studied four patients who, having received postoperative 5-fluorouracil after glaucoma filtering operations, developed serious corneal complications. All four patients had preexisting corneal abnormalities including keratoconjunctivitis sicca, exposure keratopathy, and bullous keratopathy. All of the patients devel...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74224-2
更新日期：1987-02-15 00:00:00
abstract：PURPOSE:To report a case of conjunctival intraepithelial neoplasia presenting as corneal ulcer. METHOD:Case report of a 28-year-old man who presented with sudden onset of pain, redness, and watering in the right eye. Examination of right cornea revealed deep stromal infiltrate inferonasally. Adjacent to the infiltrate...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00286-x
更新日期：2000-01-01 00:00:00
abstract：PURPOSE:To compare the long-term efficacy and safety of 2 operation methods for late in-the-bag intraocular lens (IOL) dislocation. DESIGN:Prospective, randomized, parallel group surgical clinical trial. METHODS:During a 3-year period, 104 patients (104 eyes) were assigned one group for IOL repositioning by scleral s...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2019.05.030
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:To determine whether patients can guess their intraocular pressure (IOP). DESIGN:Patient survey. METHODS:We asked consecutive patients to guess their IOP and then indicate the IOP and the symptoms that allowed them to guess. RESULTS:Of 132 patients, 22 (17%) believed they could guess their IOP, usually based...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/S0002-9394(03)00861-4
更新日期：2004-02-01 00:00:00
abstract：PURPOSE:To present an ultrasonographic finding that simulated an intraocular foreign body after repair of a ruptured globe. METHOD:Case report. An ultrasonogram of a post-trauma eye was correlated with a computed tomographic scan. RESULTS:B-scan ultrasonography was performed on an eye after repair of a corneoscleral ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71135-3
更新日期：1997-06-01 00:00:00
