Abstract：
PURPOSE:To determine with electronic monitoring an objective measurement of adherence in two populations of subjects: those using once-daily prostaglandin analogs as sole ocular hypotensive therapy (one-drug group) and those requiring an adjunctive medicine to the prostaglandin analog (two-drug group).
DESIGN:Single-site, open-label, nonrandomized, parallel design of 60 days.
METHODS:Sixty-two consecutive adult subjects with a diagnosis of open-angle glaucoma (OAG) or ocular hypertension: 31 were taking one drug and 31 were taking two drugs. An electronic event medication monitoring device was used to record each bottle opening. The main outcome measures were dosing errors (number of under-adherence or over-adherence events) and coverage (proportion of pharmacologic duration covered by dosing) relative to the ophthalmologist-prescribed regimen.
RESULTS:Adherence to the prostaglandins once daily was good in both groups by all measures ( journal_name journal_title authors doi subject pub_date pages issue eissn issn pii journal_volume pub_type
abstract：PURPOSE:To describe the ultrasound biomicroscopic features of eyes with aniridia. DESIGN:Observational case series. METHODS:Nineteen eyes of 10 patients with aniridia (six males and four females) ranging in age from 3 months to 53 years (21.0 +/- 16.4, mean +/- SD), and 50 normal subjects (30 men and 20 women) rangin...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2003.12.014
更新日期：2004-05-01 00:00:00
abstract：PURPOSE:To evaluate for which range of refractive error the optic disk size depends on, or is independent of, the refractive error. DESIGN:Clinical observational study. METHODS:The study included 1999 eyes of 1011 subjects with a mean refractive error of -0.97 +/- 2.72 diopters (range, -24.25 to +9.4 diopters). Optic...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.07.047
更新日期：2005-02-01 00:00:00
abstract：PURPOSE:To compare the incidence, prevalence, and hazard of nonexudative and exudative age-related macular degeneration (AMD) among different races throughout the United States. DESIGN:Retrospective longitudinal cohort study. METHODS:Billing records of all encounters for 2 259 061 beneficiaries aged ≥40 enrolled in a...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.02.004
更新日期：2011-08-01 00:00:00
abstract：PURPOSE:To document clinical features of uveitis in patients with familial juvenile systemic granulomatosis. DESIGN:Retrospective chart review. METHODS:Ophthalmologic examination, medical history, and clinical course in 16 patients from eight families examined at six academic medical centers. RESULTS:Of the 16 patie...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01709-9
更新日期：2002-12-01 00:00:00
abstract：:Three cases of bacterial endophthalmitis following corneal transplantation resulted from suture abscesses that were initiated by loose or broken exposed sutures. Histopathologic examination clearly demonstrated that the infection gained access to the anterior chamber by following a deeply placed suture that traversed ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(85)90217-x
更新日期：1985-02-15 00:00:00
abstract：:The noninvasive laser Doppler technique was used to study retinal circulatory characteristics in five patients who underwent uncomplicated scleral buckling procedures. In each patient, the systolic/diastolic variation of the red blood cell speed in the retinal arteries (flow pulsatility ratio) was lower in the eye tha...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(83)90012-0
更新日期：1983-02-01 00:00:00
abstract：PURPOSE:To determine the aqueous levels of vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) in patients with active polypoidal choroidal vasculopathy (PCV) and choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) and pathologic myopia. DESIGN:Pros...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2005.10.012
更新日期：2006-03-01 00:00:00
abstract：PURPOSE:To report a case of chronic recurrent varicella virus epithelial keratitis in a child. DESIGN:Case report. METHODS:Clinical examination and polymerase chain reaction analysis of corneal epithelium. RESULTS:A 10-year-old healthy child developed chronic recurrent varicella virus keratitis with pseudodendrites ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.12.014
更新日期：2005-06-01 00:00:00
abstract：:We studied the postmortem histologic characteristics of two eyes that had undergone penetrating keratoplasty and transscleral suturing of a posterior chamber intraocular lens for bullous keratopathy. The eyes were studied three days postoperatively in a 79-year-old man with pseudophakia and six months postoperatively ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76337-8
更新日期：1990-09-15 00:00:00
abstract：:Holes of the peripheral retina, defined as full-thickness breaks of trophic origin with no associated flap or free operculum, were found in 136 (2.4%) eyes from 2,800 autopsied subjects. Primary retinal holes (those with no indication of a proximal causative lesion and with no lattice degeneration in either eye) occur...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(78)90239-8
更新日期：1978-09-01 00:00:00
abstract：PURPOSE:Although congenital epiblepharon is a relatively common condition, particularly in Asians, acquired lower eyelid epiblepharon is rare. METHOD:We examined an 8-year-old boy who developed unilateral lower eyelid epiblepharon after a subciliary incisional approach for repair of a zygomatico-orbital fracture. RES...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72084-7
更新日期：1996-09-01 00:00:00
abstract：PURPOSE:To report a case of bilateral endogenous Phialemonium curvatum endophthalmitis, secondary to intrapenile injections for erectile dysfunction. DESIGN:Observational case report. METHODS:A 71-year-old man with P. curvatum endocarditis and bilateral decreased vision was diagnosed as having bilateral endogenous en...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.04.037
更新日期：2005-10-01 00:00:00
abstract：PURPOSE:To determine if a 1-day, 1-eye trial of latanoprost 0.005% was predictive of the 1-month intraocular pressure response in patients with uncontrolled open-angle glaucoma on maximally tolerated medical therapy without latanoprost. METHODS:One eye of 39 consecutive patients was enrolled in prospective trial of la...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9394(01)01253-3
更新日期：2001-12-01 00:00:00
abstract：PURPOSE:To evaluate outcomes of patients treated with intensive intravitreal therapy and to describe the evolution of quantitative real-time polymerase chain reaction (qPCR) in patients treated for acute retinal necrosis (ARN) syndrome. DESIGN:Retrospective observational case series. METHODS:This study included 25 ey...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2019.08.007
更新日期：2019-12-01 00:00:00
abstract：PURPOSE:To investigate the rate of progressive visual field (VF) loss and associated factors for structural or functional progression in preperimetric open-angle glaucoma (OAG). DESIGN:Longitudinal, observational study. METHODS:We included 127 eyes of 127 preperimetric OAG patients who were treated with topical medic...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.10.010
更新日期：2015-01-01 00:00:00
abstract：PURPOSE:To report a case of extensive cephalic and basilic venous thrombosis after fluorescein angiography. DESIGN:Interventional case report. METHODS:A 38-year-old Chinese male presented with blurring of vision in his left eye. Clinical examination revealed central serous retinopathy, and a routine fluorescein angio...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.10.058
更新日期：2005-05-01 00:00:00
abstract：PURPOSE:To determine whether treatment of macular retinoblastoma with chemotherapy and laser hyperthermia can lead to satisfactory visual acuity. METHODS:A child with unilateral macular retinoblastoma was treated with chemotherapy and laser hyperthermia. Visual function was assessed one year after treatment. RESULTS:...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75441-8
更新日期：1996-05-01 00:00:00
abstract：:We evaluated carbonic anhydrase inhibitors in a crossover study with a placebo and random allocation of treatment administration. Drugs evaluated included acetazolamide tablets and Sequels, dichlorphenamide, ethoxzolamide, methazolamide, and an ascorbic acid placebo. The best tolerated drug was acetazolamide Sequels. ...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9394(14)75247-x
更新日期：1978-04-01 00:00:00
abstract：PURPOSE:To describe clinical outcomes of complications afflicting the autologous oral mucous membrane graft after modified osteo-odonto keratoprosthesis surgery in chronic Stevens-Johnson syndrome (SJS). DESIGN:Prospective case series. METHODS:This study included 30 eyes of 30 patients with SJS-induced dry keratinize...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.06.012
更新日期：2013-11-01 00:00:00
abstract：PURPOSE:To investigate whether correction for atypical birefringence pattern (ABP) using scanning laser polarimetry with enhanced corneal compensation (SLP-ECC) reduces the severity of ABP compared with variable corneal compensation (SLP-VCC) and improves the correlation with visual function. DESIGN:Prospective observ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2006.09.049
更新日期：2007-02-01 00:00:00
abstract：PURPOSE:To describe the validation and implementation of an automated system for the detection and quantification of guttae in Fuchs endothelial corneal dystrophy (FECD). DESIGN:Observational reliability study. METHODS:Patients with FECD underwent retroillumination corneal photography, followed by determination of th...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.07.029
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:To describe two cases of acute traumatic maculopathy using optical coherence tomography (OCT) following high-speed motor vehicle accidents. DESIGN:Case reports. METHODS:Patients were examined soon after the accident using Snellen visual acuity (VA), dilated fundus examination, and OCT. Re-examination was cond...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.09.024
更新日期：2007-02-01 00:00:00
abstract：PURPOSE:To assess the long-term stability of sutured scleral-fixated posterior chamber intraocular lenses (PCIOLs) performed in combination with pars plana vitrectomy. DESIGN:Retrospective, consecutive, interventional case series. METHODS:Retrospective single-surgeon study of 118 eyes of 111 patients seen at Retina C...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.01.034
更新日期：2018-05-01 00:00:00
abstract：:Forty-three patients who initially presented with Krikenberg's spindles but with no glaucomatous field defects were observed for an average of 5.8 years in an attempt to evaluate the prognostic implication of spindle presence. Twenty-two of the patients had been followed for a minimum of five years. Analysis of the st...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90075-6
更新日期：1975-02-01 00:00:00
abstract：PURPOSE:To compare the long-term efficacy and safety of 2 operation methods for late in-the-bag intraocular lens (IOL) dislocation. DESIGN:Prospective, randomized, parallel group surgical clinical trial. METHODS:During a 3-year period, 104 patients (104 eyes) were assigned one group for IOL repositioning by scleral s...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2019.05.030
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVE:To document the clinical presentation, treatment, and visual outcome of sarcoid uveitis and to determine the timing and potential risk factors of sarcoidosis progression to symptomatic systemic disease from the time of sarcoid uveitis diagnosis. DESIGN:Retrospective, interventional case series. METHODS:Subj...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.09.013
更新日期：2019-02-01 00:00:00
abstract：PURPOSE:To describe the natural history of Leber congenital amaurosis (LCA) associated with GUCY2D variants (GUCY2D-LCA) in a cohort of children and adults, in preparation for trials of novel therapies. DESIGN:Retrospective case series. METHODS:Participants: Patients with GUCY2D-LCA at a single referral center. PROC...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2019.10.019
更新日期：2020-02-01 00:00:00
abstract：PURPOSE:To determine the incidence of cystoid macular edema (CME) after cataract surgery among eyes with and without uveitis using optical coherence tomography (OCT) and to determine risk factors for postoperative CME among eyes with uveitis. DESIGN:Prospective, comparative cohort study. METHODS:Single-center, academ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2009.02.029
更新日期：2009-07-01 00:00:00
abstract：:A graft of hard palate mucosa is a satisfactory substitute for the posterior lamella of tarsus and conjunctiva in eyelid reconstruction. The graft may be harvested after administration of local anesthesia in adults, provides structural support as well as a mucosal surface, and contracts minimally. The palatal donor si...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90257-2
更新日期：1989-06-15 00:00:00
abstract：PURPOSE:To determine the long-term outcome of glaucoma filtration surgery in preserving vision. Visual loss from progressive glaucomatous damage and from complications of surgery, both short and long term, were included. METHODS:A retrospective, community-based, longitudinal study of residents of Olmsted County, Minne...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)00923-0
更新日期：2001-07-01 00:00:00
