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Unilateral optic neuritis caused by Histoplasma capsulatum in a patient with the acquired immunodeficiency syndrome.

Abstract：

PURPOSE:To evaluate the potential of Histoplasma capsulatum to cause optic neuritis in the setting of the acquired immunodeficiency syndrome (AIDS). METHODS:We examined a 35-year-old man with a history of AIDS and disseminated histoplasmosis who developed a unilateral progressive optic neuritis of enigmatic origin. An optic nerve sheath biopsy was performed to provide a tissue diagnosis. RESULTS:Histoplasma capsulatum was identified in both the optic nerve sheath and fungal culture. CONCLUSION:Histoplasma capsulatum should be considered in the differential diagnosis of optic neuritis in patients with AIDS, even in the absence of chorioretinal findings.

journal_name

Am J Ophthalmol

journal_title

American journal of ophthalmology

authors

Yau TH,Rivera-Velazquez PM,Mark AS,Cytryn AS,Levy CS,Shmookler BM,Kolsky MP

doi

10.1016/s0002-9394(14)70285-5

subject

Has Abstract

pub_date

1996-03-01 00:00:00

pages

324-6

issue

3

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(14)70285-5

journal_volume

121

pub_type

杂志文章

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