Comparison of spectral- and time-domain optical coherence tomography for retinal thickness measurements in healthy and diseased eyes.

Abstract:

PURPOSE:To compare retinal thickness (RT) measurements obtained by spectral-domain optical coherence tomography (SD-OCT) and time-domain OCT (TD-OCT) in eyes with and without posterior segment disease diagnoses. DESIGN:Retrospective, observational chart review. METHODS:Scans of 184 healthy and diseased eyes from 106 patients were included in the study. Pair-wise comparisons of RT measurements from SD-OCT machines from 2 different manufacturers and TD-OCT were performed for all scans and with eyes stratified by disease diagnosis. RESULTS:Foveal thickness measurements obtained from both SD-OCT machines were greater than those measured by TD-OCT, by 51.0 +/- 23.8 microm and 72.5 +/- 30.4 microm, respectively. The foveal thickness difference between the 2 SD-OCT models was 24.3 +/- 19.1 microm. Foveal thickness differences varied by disease diagnosis. CONCLUSIONS:RT measurements obtained by SD-OCT are consistently greater than those obtained by TD-OCT. RT measurement differences may vary by disease diagnosis or by SD-OCT model. Consideration of these measurement differences is essential when OCT-determined RT measurement data are used in clinical settings.

journal_name

Am J Ophthalmol

authors

Han IC,Jaffe GJ

doi

10.1016/j.ajo.2008.11.019

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

847-58, 858.e1

issue

5

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(08)00900-8

journal_volume

147

pub_type

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