Abstract:
PURPOSE:To evaluate whether retinal vessel abnormalities are associated with early or late age-related macular degeneration (AMD) in adult Chinese. DESIGN:Population-based prevalence study. METHODS:The Beijing Eye Study included 4439 (83.4%) subjects of 5324 living in a rural area or urban region of Greater Beijing, age older than 40+ years, and invited to participate. The participants underwent a detailed ophthalmic examination, including fundus photography. The photographs were graded using the Wisconsin Age-Related Maculopathy Grading system for evaluation of AMD, and using the Atherosclerosis Risk in Communities protocol for assessment of retinal vascular abnormalities. We examined focal and generalized arteriolar narrowing, arteriolar sheathing, and arteriovenous crossing abnormalities. RESULTS:Fundus photographs were available for 8655 eyes of 4376 (98.6%) subjects. Neither early nor late AMD was significantly (P > .15) associated with any of the retinal vascular abnormalities. CONCLUSIONS:Retinal vascular abnormalities are not markedly associated with the prevalence of early or late AMD.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Xu L,Wang S,Li Y,Jonas JBdoi
10.1016/j.ajo.2006.05.028subject
Has Abstractpub_date
2006-10-01 00:00:00pages
688-9issue
4eissn
0002-9394issn
1879-1891pii
S0002-9394(06)00608-8journal_volume
142pub_type
杂志文章abstract:PURPOSE:To assess the risk of diabetic retinopathy (DR) in children with type 1 diabetes mellitus (T1DM) diagnosed at a very early age. DESIGN:Observational case series. METHODS:The records of 51 patients were identified through the diabetes database of the Division of Pediatric Endocrinology and Metabolism at Washin...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.05.023
更新日期:2005-11-01 00:00:00
abstract::The development of subfoveal choroidal neovascularization is a major cause of visual loss in age-related macular degeneration and other disorders of the retinal pigment epithelium-Bruch's membrane complex. We designed a new subretinal laser delivery system and used it to treat subfoveal neovascular membranes in three ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71344-3
更新日期:1993-09-15 00:00:00
abstract:PURPOSE:To investigate whether abnormal glucose metabolism and duration of diabetes mellitus (DM) affected the corneal and lens clarity in children with well-controlled type 1 DM and to compare the results obtained with those in healthy children. DESIGN:Cross-sectional prospective study. METHODS:This multicenter stud...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ajo.2017.05.010
更新日期:2017-07-01 00:00:00
abstract:PURPOSE:To describe a Japanese patient with incomplete congenital stationary night blindness (iCSNB) with atypical retinal atrophy and kinetic visual field defects. METHODS:An ophthalmologic examination was performed, and the CACNA1F gene was analyzed by direct genomic sequencing. RESULTS:The patient had a hemizygous...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01541-6
更新日期:2002-09-01 00:00:00
abstract::We performed serial slit-lamp examinations and topography analysis on a patient whose initial topographic map suggested a diagnosis of keratoconus to us but which others interpreted as normal topography. Topography analysis documented cone progression during a two-year period. The initial map showed a cone apex power ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)76210-5
更新日期:1991-07-15 00:00:00
abstract:PURPOSE:To report the occurrences of early rapid increases in intraocular (IOP) after intravitreal glucocorticoid injection. DESIGN:Observational case series. METHODS:We retrospectively reviewed the records of three patients seen and treated at Duke Eye Center. RESULTS:In all three cases, a significant rise in IOP o...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.03.001
更新日期:2004-08-01 00:00:00
abstract:PURPOSE:To correlate in vivo confocal microscopy morphologic features (IVCM-MF) and Acanthamoeba cyst density (ACD) with final best-corrected visual acuity (BCVA) in Acanthamoeba keratitis (AK). DESIGN:Retrospective cohort study. METHODS:Patient demographics, treatment outcome, and corresponding IVCM-MF performed at ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.03.048
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To report a case of nodular scleritis and panuveitis associated with erythema elevatum diutinum, a rare immunocomplex-mediated skin disease. DESIGN:Observational case report. METHODS:A 22-year-old woman who was diagnosed with erythema elevatum diutinum developed nodular scleritis and panuveitis of the right e...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/S0002-9394(03)00907-3
更新日期:2004-02-01 00:00:00
abstract:PURPOSE:To report on the presence of retinal pigment epithelium (RPE) humps in high myopia, and to describe the distinctive features from pathologic RPE detachments and choroidal neovascularizations (CNVs). DESIGN:Retrospective cross-sectional study. METHODS:Charts and imaging studies of highly myopic patients presen...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.07.013
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:To use micro-ribonucleic acid (microRNA) profiles in the vitreous for differential diagnosis of primary vitreoretinal lymphoma and uveitis. DESIGN:Prospective cross-sectional study. METHODS:This prospective cross-sectional study included 17 diffuse large B-cell primary vitreoretinal lymphoma and 12 uveitis pa...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2013.12.014
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:To report a case of congenital superior oblique palsy with an unusually large Bielschowsky head-tilt phenomenon (BHP) and disproportional inconspicuous vertical deviation. METHODS:Case report. RESULTS:An 18-year-old woman presented with slight compensatory head tilting and a Bielschowsky head-tilt phenomenon ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00639-5
更新日期:2000-12-01 00:00:00
abstract::Three hundred two cases of epibulbar tumors in children were retrospectively reviewed histologically and examined by diagnostic categories over a 49-year period. Of the 302 cases, 33% were choristomas; 29% nevi; 11%, epithelial inclusion cysts; 7%, papillomas; 6%, pyogenic granulomas; and 5% granulomas. Three cases of...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90685-6
更新日期:1975-06-01 00:00:00
abstract:PURPOSE:To describe intentional placement of intraocular lens haptics in the ciliary sulcus of patients with uveitis who are at high risk for postoperative posterior synechiae and lens dislocation. METHODS:We reviewed our experience with 16 eyes of 12 patients with uveitis who underwent cataract surgery with ciliary s...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00140-3
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:To evaluate the importance of nutritional supplements, dietary pattern, and genetic associations in age-related macular degeneration (AMD); and to discuss the technique of artificial intelligence/deep learning to potentially enhance research in detecting and classifying AMD. DESIGN:Retrospective literature rev...
journal_title:American journal of ophthalmology
pub_type:
doi:10.1016/j.ajo.2020.05.042
更新日期:2020-09-01 00:00:00
abstract::The diameter of retinal arterioles, venules, and their macular branches was measured before and after macular laser photocoagulation in one eye each of six men and eight women with diabetic macular edema. The macular arteriolar branches constricted 20.2% (P < .001) and the venular branches constricted 13.8% (P < .001)...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73526-3
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:To investigate whether retina damaged in the process of air/fluid exchange could be visualized in situ using trypan blue staining. METHODS:Vitrectomy and air/fluid exchange with continuous air infusion for various periods of time was performed in adult pigmented rabbits, followed by injection of 0.4% trypan bl...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00927-2
更新日期:2001-06-01 00:00:00
abstract::We combined a recession or resection of recti muscles with a vertical or horizontal transposition to correct a complicated paralytic ocular deviation in eight patients. The transposed muscles were reattached to the globe parallel to the spiral of Tillaux and adjacent to the paralyzed muscle. Postoperatively, seven pat...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72313-x
更新日期:1991-03-15 00:00:00
abstract:PURPOSE:To describe the presentation and subsequent management of a case of severe gonococcal keratitis in a young man. DESIGN:Case report. METHODS:A young man presented with severe gonococcal keratitis. Topical and systemic antibiotics were given with no improvement, and progressive corneal melting was noted. Deep l...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.04.014
更新日期:2004-09-01 00:00:00
abstract::We noted two instances of forceps-induced fragmentation of the bar used for scleral plug storage during vitreous surgery. The silicone bar material was adherent to the plug in both cases. Because this represents a significant intraocular foreign body hazard, the scleral plug should be carefully inspected before insert...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(82)90542-6
更新日期:1982-03-01 00:00:00
abstract:PURPOSE:To describe clinical outcomes of complications afflicting the autologous oral mucous membrane graft after modified osteo-odonto keratoprosthesis surgery in chronic Stevens-Johnson syndrome (SJS). DESIGN:Prospective case series. METHODS:This study included 30 eyes of 30 patients with SJS-induced dry keratinize...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2013.06.012
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:To evaluate whether quantity of choroidal tissue directly adjacent to the optic nerve differs between eyes with and without glaucoma and whether beta-zone parapapillary atrophy influences this relationship. DESIGN:Prospective cohort study. METHODS:Subjects were enrolled in a longitudinal, observational study ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2015.06.024
更新日期:2015-10-01 00:00:00
abstract::A 55-year-old man had organized hemorrhage into retinoschisis that simulated malignant melanoma both clinically and with ultrasonography. The correct diagnosis was made histopathologically after enucleation. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90199-5
更新日期:1979-01-01 00:00:00
abstract:PURPOSE:To determine the incidence of cystoid macular edema (CME) after cataract surgery among eyes with and without uveitis using optical coherence tomography (OCT) and to determine risk factors for postoperative CME among eyes with uveitis. DESIGN:Prospective, comparative cohort study. METHODS:Single-center, academ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.02.029
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:Age-related maculopathy (ARM) and cognitive impairment are both neurodegenerative disorders associated with aging and have been hypothesized to share common pathogenic pathways. We describe the association between cognitive function and ARM in middle-aged persons. DESIGN:Population-based, cross-sectional study...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01672-0
更新日期:2002-12-01 00:00:00
abstract:PURPOSE:Central retinal artery occlusion (CRAO) is mechanistically similar to a stroke. Current guidelines recommend a standardized and systematic evaluation of risk factors for patients who have had a stroke. This study evaluates the yield of this evaluation in patients with CRAO and frequency of stroke in this popula...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.08.027
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:To report the association of Marcus Gunn jaw-winking phenomenon and pseudo inferior oblique overaction. METHODS:Case report. RESULTS:A 21-year-old woman presented with right eyelid elevation on the chewing movement since infancy. Examination showed that both Marcus Gunn jaw-winking phenomenon and pseudo infer...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00705-4
更新日期:2001-01-01 00:00:00
abstract::We followed up 32 eyes of 32 patients with early glaucoma (22 with capsular glaucoma and ten with simple glaucoma) who received laser trabeculoplasty as a primary therapy. These eyes were compared with a matched control group of 32 eyes treated with medication initially. The success rate (intraocular pressure below 22...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(87)90220-0
更新日期:1987-10-15 00:00:00
abstract:PURPOSE:To document a branch retinal vein obstruction secondary to a congenital arteriovenous communication. METHOD:Case report of a young patient with retinal arteriovenous communication. RESULTS:A 12-year-old girl had a grade 2 retinal arteriovenous communication in her right eye. She was asymptomatic and was subse...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00103-2
更新日期:1998-09-01 00:00:00
abstract::Confirmation of iodine-125 plaque position was determined with a modified fiberoptic light pipe that directed light at right angles to the long axis of the fiberoptic pipe. While the examiner observed the interior of the eye with indirect ophthalmoscopy, the point source of light from the fiberoptic light pipe was mov...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74171-6
更新日期:1987-01-15 00:00:00
abstract:PURPOSE:To investigate the fundus autofluorescence (FAF) imaging findings in patients with serous and drusenoid pigment epithelial detachment (PED) associated with age-related macular degeneration (AMD). DESIGN:Observational case series. METHODS:Fourteen eyes of 13 consecutive patients with serous (n = 10) and drusen...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.07.037
更新日期:2005-12-01 00:00:00