Abstract：
PURPOSE:To investigate whether retina damaged in the process of air/fluid exchange could be visualized in situ using trypan blue staining. METHODS:Vitrectomy and air/fluid exchange with continuous air infusion for various periods of time was performed in adult pigmented rabbits, followed by injection of 0.4% trypan blue solution into the vitreous cavity. Retinal staining was evaluated intraoperatively under the operating microscope and by light microscopy after enucleation. RESULTS:Intraoperative examination showed localized trypan blue staining of areas of the retina opposite the infusion cannula. Light microscopy of the same areas revealed intranuclear trypan blue inclusion in the retina. CONCLUSION:Trypan blue staining allows for the immediate in situ evaluation of damage to the retina associated with air/fluid exchange and continuous air infusion in rabbit eyes.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Oshitari K,Hirakata A,Nagamoto T,Okada AA,Hida Tdoi
10.1016/s0002-9394(00)00927-2subject
Has Abstractpub_date
2001-06-01 00:00:00pages
814-5issue
6eissn
0002-9394issn
1879-1891pii
S0002939400009272journal_volume
131pub_type
杂志文章abstract：PURPOSE:To report a case of migration of liquid silicone into the upper eyelid. DESIGN:Interventional case report. METHODS:A 32-year-old woman had an injection of liquid silicone into the subcutaneous tissue of the forehead. She developed a cystic mass in the upper eyelid 2 days postinjection. An excisional biopsy wa...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00465-3
更新日期：2003-11-01 00:00:00
abstract：:A 32-year-old obese woman with hypertension and a three-year history of pseudotumor cerebri developed bilateral juxtapapillary subretinal neovascular membranes. To our knowledge, this is the first reported case of bilateral subretinal neovascular membranes complicating the course of this disease. The subretinal neovas...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(81)90282-8
更新日期：1981-03-01 00:00:00
abstract：:Pars plana vitrectomy and scleral buckling were performed on 22 eyes of 19 patients for treatment of perforating eye injuries from shotgun pellets. We reviewed the intraoperative findings at the time of vitrectomy to determine what factors might influence final visual acuity. The presence of a total retinal detachment...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)77416-1
更新日期：1992-07-15 00:00:00
abstract：PURPOSE:To report a case of small cell carcinoma of the thymus metastatic to the orbit. METHODS:At age 37 years, a man who had been previously diagnosed and treated for small cell carcinoma of the thymus was initially examined for vertical diplopia and left proptosis. Computed tomographic scan disclosed a soft tissue ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70836-0
更新日期：1997-09-01 00:00:00
abstract：:Surgical treatments of macular holes have become increasingly effective in inducing resolution of the cuff of surrounding subretinal fluid, resulting in increased vision in many patients. However, for many conditions that mimic a macular hole, either surgery is not indicated or different surgical manipulations are nec...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70319-8
更新日期：1994-06-15 00:00:00
abstract：PURPOSE:To report a case of presumed congenital hypertrophy of the retinal pigment epithelium in the fovea of an 88-year-old woman in the setting of geographic atrophy from age-related macular degeneration. DESIGN:Observational case report. METHODS:An 88-year-old woman was examined. RESULTS:Best-corrected visual acu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01845-7
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:To seek evidence of neurovascular compression of motor cranial nerves (CNs) in otherwise idiopathic neuropathic strabismus using high-resolution magnetic resonance imaging (MRI). DESIGN:Prospective, observational case series. METHODS:High-resolution, surface coil orbital MRI was performed in 10 strabismic pat...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.05.031
更新日期：2011-12-01 00:00:00
abstract：PURPOSE:To report a patient with idiopathic retinal venous beading and recurrent preretinal hemorrhage. METHOD:Case report of a 17-year-old girl with bilateral retinal venous beading, greater in the left eye than in the right eye, and recurrent preretinal hemorrhage in the left eye. RESULTS:Complete blood cell count,...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71087-6
更新日期：1997-05-01 00:00:00
abstract：:Ciprofloxacin is a potent fluoroquinolone antibiotic with in vitro activity against many significant gram-positive and gram-negative ocular pathogens. A review of the experimental studies of this antibiotic shows bactericidal activity, a broad antimicrobial spectrum, and a low incidence of resistance. The growing body...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1991-10-01 00:00:00
abstract：PURPOSE:To measure lead and cadmium in retinal tissues of human donor eyes with and without age-related macular degeneration (AMD). DESIGN:Laboratory investigation. METHODS:Lead and cadmium concentrations in retinal tissues (neural retina and retinal pigment epithelium [RPE]-choroid complex) in 25 subjects with AMD (...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2009.07.001
更新日期：2009-12-01 00:00:00
abstract：PURPOSE:To assess the potential effect of intravitreal bevacizumab (IVB) (Avastin) on retinal function and anatomic recovery in eyes with choroidal neovascularization attributable to pathological myopia (mCNV). DESIGN:Retrospective case series. METHODS:setting: Institutional. patient population: Sixty-three eyes of 6...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.07.017
更新日期：2009-01-01 00:00:00
abstract：PURPOSE:To describe a Japanese patient with incomplete congenital stationary night blindness (iCSNB) with atypical retinal atrophy and kinetic visual field defects. METHODS:An ophthalmologic examination was performed, and the CACNA1F gene was analyzed by direct genomic sequencing. RESULTS:The patient had a hemizygous...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01541-6
更新日期：2002-09-01 00:00:00
abstract：:Visual field testing of 166 phakic eyes with optic nerve damage from open-angle glaucoma before and after one year of treatment showed that the visual fields of myopic eyes improved more often than those of nonmyopic eyes (12% vs 6%) and worsened less often (6% vs 18%). These results suggested that myopia, which adver...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)77378-7
更新日期：1982-05-01 00:00:00
abstract：PURPOSE:In previous studies of fungal keratitis (FK) from temperate countries, yeasts were the predominant isolates, with ocular surface disease (OSD) being the leading risk factor. Since the 2005-2006 outbreak of contact lens (CL)-associated Fusarium keratitis, there may have been a rise in CL-associated filamentary F...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2016.05.021
更新日期：2016-08-01 00:00:00
abstract：PURPOSE:To report two patients with severe fungal corneal ulcers who were treated successfully with topical amphotericin B ointment. METHODS:Two eyes of two patients developed corneal ulcers and hypopyon after corneal foreign body removal. Aspergillus fumigatus and Fusarium solani were isolated in Patients 1 and 2, re...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71701-5
更新日期：1997-12-01 00:00:00
abstract：PURPOSE:To describe the relationship between the incidence of age-related macular degeneration (AMD) and nonsteroidal anti-inflammatory drug (NSAIDs) use. DESIGN:Prospective cohort study. METHODS:This study consisted of participants in the California Men's Health Study. Those who completed surveys in 2002-2003 and 20...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.01.012
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:To describe the validation and implementation of an automated system for the detection and quantification of guttae in Fuchs endothelial corneal dystrophy (FECD). DESIGN:Observational reliability study. METHODS:Patients with FECD underwent retroillumination corneal photography, followed by determination of th...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.07.029
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:To report the response of calcification in choroidal melanoma after transpupillary thermotherapy. METHODS:Interventional case report. A 66-year-old male with a posterior uveal melanoma measuring 10 x 8 x 4.4 mm underwent infrared diode laser transpupillary thermotherapy three times, each 12 weeks apart. For ea...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01186-2
更新日期：2001-12-01 00:00:00
abstract：:A 26-year-old woman experienced bilateral hearing loss, progressive nasal obstruction, and rhinorrhea. Examination disclosed a retropharyngeal mass. A needle biopsy specimen of the mass showed that it was a chordoma. The patient underwent surgery to remove the mass and received a postoperative course of radioactive co...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75899-4
更新日期：1981-07-01 00:00:00
abstract：:The Prospective Evaluation of Radial Keratotomy Study is a nine-center clinical trial of a standardized technique of radial keratotomy in 435 patients who had simple myopia with a preoperative refraction between -2.00 and -8.00 diopters. We studied the stability of the refractive error during four years after surgery ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72250-0
更新日期：1991-02-15 00:00:00
abstract：:Total outflow facility was determined in cynomolgus monkeys by two-level constant pressure perfusion. Topical epinephrine increased facility by 30% to 35% three to four hours after dosing, whether given as a single 600-micrograms dose or as twice daily 600-micrograms doses for three days. A single 5.5-micrograms intra...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75985-9
更新日期：1990-02-15 00:00:00
abstract：PURPOSE:To assess whether successful surgical intervention for intermittent exotropia, or the timing of intervention, has any effect on the development of mental illness. DESIGN:Retrospective, observational case series. METHODS:All patients (<19 years of age) diagnosed with intermittent exotropia in Olmsted County, M...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.06.008
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:To compare immunocytochemical and ultrastructural characteristics of "lamellar hole-associated epiretinal proliferation" in lamellar macular holes with "conventional epiretinal membrane" in macular pseudoholes. DESIGN:A consecutive observational case series, laboratory investigation. METHODS:We analyzed surgi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.05.010
更新日期：2015-08-01 00:00:00
abstract：PURPOSE:To investigate the prevalence of peripheral pigmented retinal lesions and associated clinical findings in patients with Stargardt disease. DESIGN:Retrospective case series. METHODS:Records at a single academic institution were reviewed for patients with genetically confirmed Stargardt disease with peripheral ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.12.011
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:To determine the amount and time course of binocular visual acuity improvement during treatment of bilateral refractive amblyopia in children three to less than 10 years of age. DESIGN:Prospective, multicenter, noncomparative intervention. METHODS:One hundred and thirteen children (mean age, 5.1 years) with p...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2007.05.040
更新日期：2007-10-01 00:00:00
abstract：PURPOSE:To assess the association between smoking, alcohol intake, estrogen use, and both early age-related macular degeneration (AMD) (soft indistinct drusen, retinal pigment abnormalities) and advanced AMD (exudative AMD, geographic atrophy) in the Latino community. DESIGN:Population-based, cross-sectional study. M...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.08.024
更新日期：2006-01-01 00:00:00
abstract：:We evaluated the effect of a collagen shield on epithelial healing in keratectomy wounds in rabbit eyes. Superficial keratectomies 6 mm in diameter were created in 12 eyes of six rabbits. Six eyes received collagen shields every eight hours; six eyes received no treatment (control group). Epithelial healing was signif...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90428-5
更新日期：1989-11-15 00:00:00
abstract：PURPOSE:To assess the role of hypoxia in causing the death and deconstruction of photoreceptors in detached retinas and the effectiveness of supplemental oxygen in limiting such damage. METHODS:Retinal detachment was induced surgically in the right eye of each of 10 cats. The cats were allowed to survive surgery for 3...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00104-x
更新日期：1999-08-01 00:00:00
abstract：PURPOSE:To investigate the impact on patient management of posterior segment echographic evaluation at an academic institution. DESIGN:Retrospective, noncomparative, consecutive case series. METHODS:Records were reviewed of all patients evaluated for the first time with ocular echography for posterior segment evaluat...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00910-3
更新日期：2004-01-01 00:00:00
abstract：:A 62-year-old woman developed a recurrent mucinous sweat gland adenocarcinoma of the eyelid. The clinical characteristics of this rare, primary adnexal neoplasm of skin in our patient were, to our knowledge, unique. The tumor mimicked a lacrimal sac tumor and had orbital extension demonstrated preoperatively by comput...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(81)90767-4
更新日期：1981-08-01 00:00:00
