Abstract:
:Ciprofloxacin is a potent fluoroquinolone antibiotic with in vitro activity against many significant gram-positive and gram-negative ocular pathogens. A review of the experimental studies of this antibiotic shows bactericidal activity, a broad antimicrobial spectrum, and a low incidence of resistance. The growing body of experimental data supports the effectiveness of ciprofloxacin in the treatment of experimental keratitis and suggest that it be evaluated further in ocular infections.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Cokingtin CD,Hyndiuk RAsubject
Has Abstractpub_date
1991-10-01 00:00:00pages
25S-28Sissue
4 Suppleissn
0002-9394issn
1879-1891journal_volume
112pub_type
杂志文章,评审abstract:PURPOSE:Periventricular leukomalacia (PVL) is a structural loss of white matter pathways that carry visual information from the lateral geniculate bodies to the visual cortex. It is observed radiologically in patients with a history of prematurity and is associated with visual field (VF) defects and optic disc cupping....
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.10.016
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To investigate the anatomic and visual outcomes in patients with initial anatomic success after macular hole surgery and with at least 5 years of follow-up. DESIGN:Retrospective, noncomparative, consecutive case series. METHODS:Medical records of all patients who underwent surgery for idiopathic full-thicknes...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)02240-7
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:To provide evidence that corticosteroid-induced ocular hypertension has a genetic component. DESIGN:Evidence-based perspective. METHODS:We conducted a comprehensive literature search for studies exploring genetic influences on intraocular pressure responses to corticosteroid treatment. RESULTS:Studies demons...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/j.ajo.2019.02.001
更新日期:2019-06-01 00:00:00
abstract::Two groups of patients, 37 with primary basal cell carcinoma of the eyelid and 16 with basal cell carcinoma of the eyelid previously treated by other physicians were reviewed. All of the tumors were excised with at least 3 to 4 mm of normal-appearing tissue at each margin of resection. All of the excised specimens wer...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90358-1
更新日期:1979-06-01 00:00:00
abstract:PURPOSE:To compare the efficacy of intraoperative scleral application with subconjunctival injection of mitomycin C (MMC) in trabeculectomy. DESIGN:Prospective, randomized, interventional study. METHODS:This study took place in a single clinical practice in an academic setting. Patients had medically uncontrolled gla...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ajo.2020.07.002
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To determine the amount and time course of binocular visual acuity improvement during treatment of bilateral refractive amblyopia in children three to less than 10 years of age. DESIGN:Prospective, multicenter, noncomparative intervention. METHODS:One hundred and thirteen children (mean age, 5.1 years) with p...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2007.05.040
更新日期:2007-10-01 00:00:00
abstract:PURPOSE:To classify and describe clinically meaningful classes of color vision defects using pretreatment Farnsworth-Munsell 100-hue results from the Early Treatment Diabetic Retinopathy Study (ETDRS) patients using standard statistical techniques. DESIGN:The ETDRS was a randomized trial investigating retinal photocoa...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ajo.2004.02.009
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:To detect the abnormalities of gray matter in children with amblyopia by voxel-based morphometry (VBM). DESIGN:Prospective, nonrandomized clinical trial. METHODS:Thirteen children with amblyopia and 14 normally sighted children underwent magnetic resonance (MR) examination. The two groups were age-matched wit...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ajo.2006.11.039
更新日期:2007-03-01 00:00:00
abstract:PURPOSE:To determine whether central corneal thickness (CCT) is a risk factor for visual field loss development among patients diagnosed with preperimetric glaucomatous optic neuropathy (GON). DESIGN:Observational cohort study. METHODS:The study included 98 eyes of 98 patients with GON, with a mean follow-up time of ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00484-7
更新日期:2003-11-01 00:00:00
abstract::We analyzed 34 sets of optic disk photographs from 19 patients with glaucoma who had been followed up for ten years to evaluate changes in the position of the vasculature of the optic disks over time. Each photograph was analyzed by an image analyzer's edge-defining program for optic disk analysis and by three experie...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74101-7
更新日期:1987-11-15 00:00:00
abstract:PURPOSE:To determine the origin of scleritis, uveitis, and glaucoma in a boy with fever, sore throat, joint pains, and malaise. METHODS:The patient underwent extensive hematologic, serologic, rheumatologic, and radiologic examinations. RESULTS:The patient recovered after extensive medical therapy. He met the Jones cr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72676-5
更新日期:1995-10-01 00:00:00
abstract::A prospective study of 78 eyes with idiopathic preretinal macular gliosis disclosed that 74 of the 78 (95%) had posterior vitreous detachments at the time of the initial examination. A second prospective study of 34 eyes with acute posterior vitreous detachment showed preretinal macular gliosis in three eyes (9%) init...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(86)90144-3
更新日期:1986-08-15 00:00:00
abstract::The noninvasive laser Doppler technique was used to study retinal circulatory characteristics in five patients who underwent uncomplicated scleral buckling procedures. In each patient, the systolic/diastolic variation of the red blood cell speed in the retinal arteries (flow pulsatility ratio) was lower in the eye tha...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(83)90012-0
更新日期:1983-02-01 00:00:00
abstract::A 29-year-old white man developed a corneal ulcer following trauma to his left cornea by a piece of wire. Tritirachium roseum, a saprophytic fungus, was cultured from corneal scrapings and demonstrated in the corneal button by histopathologic examination. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90275-5
更新日期:1975-11-01 00:00:00
abstract:PURPOSE:Longstanding corneal edema can lead to anterior stromal scarring that may limit visual acuity following Descemet stripping endothelial keratoplasty (DSEK). The ideal time to perform DSEK to prevent permanent changes is unclear. Our aim is to determine whether earlier DSEK is associated with improved visual outc...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.09.006
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:To determine whether parapapillary choroidal microvasculature (PPCMv) density as measured by optical coherence tomography angiography differs between pseudoexfoliation syndrome (PXS) and pseudoexfoliation glaucoma (PXG). DESIGN:Cross-sectional study. METHODS:One hundred ninety-two eyes of 120 subjects from ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.12.002
更新日期:2020-12-10 00:00:00
abstract:PURPOSE:To determine whether higher-order aberrations can explain the monocular diplopia reported by a patient. DESIGN:Observational case report. METHODS:A patient complaining of monocular diplopia was examined with the Hartmann-Shack aberrometer to determine if the higher-order wavefront aberrations could account fo...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.12.040
更新日期:2006-06-01 00:00:00
abstract:PURPOSE:To compare polymerase chain reaction (PCR) results to presumptive clinical diagnosis in patients with vitritis. DESIGN:Retrospective review of PCR laboratory records from vitreous samples. METHODS:Fifty consecutive laboratory records of vitreous samples sent for PCR testing were reviewed. Three reviewers with...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.10.011
更新日期:2006-03-01 00:00:00
abstract::A 34-year-old man had a six-month history of bilateral visual loss that was secondary to cystoid macular edema, which was assumed to be secondary to neurosyphilis on the basis of cerebrospinal fluid serology, cell count, and protein. Good visual acuity was recovered with systemic corticosteroids only after they were u...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90747-5
更新日期:1979-07-01 00:00:00
abstract:PURPOSE:To report a case of presumed congenital hypertrophy of the retinal pigment epithelium in the fovea of an 88-year-old woman in the setting of geographic atrophy from age-related macular degeneration. DESIGN:Observational case report. METHODS:An 88-year-old woman was examined. RESULTS:Best-corrected visual acu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01845-7
更新日期:2003-01-01 00:00:00
abstract::Extraocular bacterial culture was performed in 100 patients with hypovitaminosis A xerophthalmia. There was corneal ulceration in 29 cases and corneal perforation in 22 cases. Eighty-six percent of the patients harbored frankly pathogenic bacteria (46 patients) and potentially pathogenic bacteria (40 patients). All bu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90399-2
更新日期:1975-10-01 00:00:00
abstract:PURPOSE:To report molluscum contagiosum as the initial manifestation in acquired immunodeficiency syndrome (AIDS). METHOD:Case report. A 34-year-old man was examined with atypical, extensive molluscum contagiosum of the eyelids. RESULTS:Biopsy of the lesions confirmed molluscum contagiosum, and a previously normal fu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70791-3
更新日期:1997-08-01 00:00:00
abstract:PURPOSE:To determine whether the risk of graft failure in patients with glaucoma is dependent on the indication for penetrating keratoplasty (PK). DESIGN:Retrospective cohort study. METHODS:All patients on the United Kingdom Transplant Registry undergoing their first PK over a 7-year period with at least 1 year of fo...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2010.08.018
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To provide additional evidence that anterior uveitis can be a manifestation of poststreptococcal syndrome. METHOD:A case report providing follow-up information on a previously described patient. RESULTS:An adolescent girl in whom anterior uveitis was the only manifestation of poststreptococcal syndrome subseq...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1999-03-01 00:00:00
abstract::Of nine patients (five men and four women, 25 to 55 years old) with localized orbital neurofibromas, only one had other systemic findings consistent with neurofibromatosis. The neurofibromas originated from sensory nerves of the orbit, producing gradual proptosis with expansion of the orbital walls in most cases. Mild...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(85)90514-8
更新日期:1985-09-15 00:00:00
abstract::During the last four years we treated 82 consecutive patients (83 eyes) with retinal detachments complicated by proliferative vitreoretinopathy. We used pars plana vitrectomy combined with a broad scleral buckle, cryotherapy to the retinal breaks, and a temporary intraocular gas bubble. The retina was successfully rea...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(84)90683-4
更新日期:1984-12-15 00:00:00
abstract::Between 1976 and 1982, we examined 13 patients with clinical and radiographic findings consistent with optic nerve sheath meningioma. All patients had visual loss, evidence of optic nerve dysfunction, centrocecal visual field defects, and echographic and computed tomographic evidence of optic nerve or sheath enlargeme...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(85)90506-9
更新日期:1985-09-15 00:00:00
abstract:PURPOSE:To report a case of bilateral endogenous Phialemonium curvatum endophthalmitis, secondary to intrapenile injections for erectile dysfunction. DESIGN:Observational case report. METHODS:A 71-year-old man with P. curvatum endocarditis and bilateral decreased vision was diagnosed as having bilateral endogenous en...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.04.037
更新日期:2005-10-01 00:00:00
abstract:PURPOSE:To investigate in open-angle glaucoma the focal macular photopic negative response and spectral-domain optical coherence tomography measurements of retinal thicknesses in the superior and inferior macula. DESIGN:Comparative case series. METHODS:We studied 63 eyes of 63 patients with open-angle glaucoma and 41...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2010.09.018
更新日期:2011-03-01 00:00:00
abstract::A 2,000-g infant boy had many features of the Smith-Lemli-Opitz syndrome (prenatal growth deficiency and developmental retardation, microcephaly with unusual facies, hypospadias, and feeding difficulties) as well as sclerocornea. The association of this rare eye finding with this rare congenital syndrome is unique. Su...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(77)90327-0
更新日期:1977-07-01 00:00:00