Abstract：
:We performed serial slit-lamp examinations and topography analysis on a patient whose initial topographic map suggested a diagnosis of keratoconus to us but which others interpreted as normal topography. Topography analysis documented cone progression during a two-year period. The initial map showed a cone apex power of 44.5 diopters located 2.1 mm inferior to the vertex normal. An oblong-shaped area of maximum power was surrounded by concentric bands of lower power. Corneal surface power ranged from 41.5 to 44.5 diopters. Two years later cone apex power increased to 51.0 diopters, and the patient developed a Fleischer's ring, Vogt's striae, and mild visual aberration. Our findings suggest the use of topography analysis systems in documenting subclinical cone progression. Topography systems may be a useful tool in the study of the true incidence and natural progression of subclinical keratoconus.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Maguire LJ,Lowry JCdoi
10.1016/s0002-9394(14)76210-5subject
Has Abstractpub_date
1991-07-15 00:00:00pages
41-5issue
1eissn
0002-9394issn
1879-1891pii
S0002-9394(14)76210-5journal_volume
112pub_type
杂志文章abstract：PURPOSE:To describe a newly identified clinical entity tentatively named white dot fovea. METHODS:We examined by scanning laser ophthalmoscopy 58 eyes of 30 patients (mean age, 64 years) who had white dots in the fovea (anatomically defined as the foveola) simulating macular hole. In addition, the retinal surfaces of ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70995-x
更新日期：1997-01-01 00:00:00
abstract：:We examined three affected members of a Chinese-American family with Bietti's crystalline retinopathy. The clinical characteristics of a 24-year-old proband are contrasted to the clinical findings of her grandmother, for whom we have 26 years of follow-up data. Lymphocytes and fibroblasts from a skin biopsy of the gra...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76572-9
更新日期：1994-11-15 00:00:00
abstract：PURPOSE:To study the effect of higher-order aberrations (HOAs) on visual function in keratoconus with a rigid gas permeable (RGP) contact lens (CLs). DESIGN:Retrospective nonrandomized study. METHODS:Thirteen eyes of 10 subjects with keratoconus who wore a RGP CLs (KC-RGP group), 15 eyes of nine normal subjects (norm...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.08.004
更新日期：2007-12-01 00:00:00
abstract：PURPOSE:To describe a case of spontaneous retrobulbar hemorrhage in type IV Ehlers-Danlos syndrome, a disorder characterized by vascular fragility and associated severe bleeding problems. METHODS:Observational case report. Spontaneous unilateral retrobulbar hemorrhage in a 22-year-old man with type IV Ehlers-Danlos sy...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01325-3
更新日期：2002-03-01 00:00:00
abstract：:There is no single method of perimetric examination which is applicable to all types of visual field defects. Perimetry is a subjective psychophysical sensory examination. It is not an exact science unless one includes the objective measurement of visual evoked response in the optic cortex. Until such a method becomes...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90527-9
更新日期：1975-09-01 00:00:00
abstract：PURPOSE:To describe and quantify the appearance of the optic disk in patients with advanced age-related macular degeneration (ARMD). DESIGN:Retrospective comparative study. METHODS:A total of 316 charts were reviewed. From these, 45 subjects with advanced ARMD (defined as geographic atrophy or disciform scar) in at l...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.02.021
更新日期：2004-07-01 00:00:00
abstract：PURPOSE:To determine the incidence of and risk factors for cataract and to describe the visual outcomes of cataract surgery in eyes with cytomegalovirus-related retinal detachments repaired with silicone oil. STUDY DESIGN:Retrospective cohort study. METHODS:A prospectively generated database of all patients with cyto...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00724-4
更新日期：2003-12-01 00:00:00
abstract：PURPOSE:To report an unusual complication of accommodative intraocular lens (IOL) implantation after clear lens extraction for hyperopia correction. DESIGN:Observational case report. METHOD:A 48-year-old woman underwent clear lens exchange for the correction of moderate hyperopia. A Crystalens Model AT-45 Accommodati...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.02.040
更新日期：2005-08-01 00:00:00
abstract：PURPOSE:To examine the occurrence and outcome of methicillin-resistant Staphylococcus aureus ophthalmologic infections in a newborn intensive care unit cohort. DESIGN:Noninterventional case series. METHODS:Over a 13-month period, 29 neonates were colonized with methicillin-resistant S. aureus in a newborn intensive c...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.02.019
更新日期：2006-07-01 00:00:00
abstract：PURPOSE:To report the use of an Apligraf (Organogenesis, Inc., Canton, Massachusetts, USA) human skin equivalent for repair of cicatricial ectropion in a patient with harlequin ichthyosis. DESIGN:Interventional case report. METHODS:A 6-week-old male child with harlequin ichthyosis and severe bilateral upper eyelid ci...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01567-2
更新日期：2002-09-01 00:00:00
abstract：PURPOSE:To present a new surgical technique for severe, symptomatic conjunctivochalasis and our hypothesis of the pathogenesis of this condition. METHODS:Six eyes of three patients with conjunctivochalasis (average age +/-SD, 70.0 +/- 9.6 years; range, 56-78 years) were treated with a conjunctival fixation to sclera w...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00384-0
更新日期：2000-03-01 00:00:00
abstract：PURPOSE:To evaluate the effect of macular reticular pseudodrusen on retinal function using multiple imaging methods. DESIGN:Prospective cross-sectional study. METHODS:Thirteen eyes with reticular pseudodrusen, but without any other macular abnormality or glaucoma, and 20 normal eyes were evaluated. All subjects under...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.06.036
更新日期：2013-12-01 00:00:00
abstract：PURPOSE:To investigate whether retina damaged in the process of air/fluid exchange could be visualized in situ using trypan blue staining. METHODS:Vitrectomy and air/fluid exchange with continuous air infusion for various periods of time was performed in adult pigmented rabbits, followed by injection of 0.4% trypan bl...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00927-2
更新日期：2001-06-01 00:00:00
abstract：PURPOSE:To characterize perifoveal intraretinal cavities observed around full-thickness macular holes (MH) using en face optical coherence tomography and to establish correlations with histology of human and primate maculae. DESIGN:Retrospective nonconsecutive observational case series. METHODS:Macular en face scans ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.02.013
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:To evaluate the indications for and outcomes of intraocular lens (IOL) exchange at the same clinical setting over the past decade, as well as compare the efficacy and safety of anterior chamber lens (AC-IOL) and posterior chamber lens (PC-IOL) implantation for IOL exchange. DESIGN:Retrospective, nonrandomized ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.05.015
更新日期：2005-10-01 00:00:00
abstract：PURPOSE:To describe a technique that uses a transcorneal suture for safe delivery and fixation of donor tissue during Descemet stripping automated endothelial keratoplasty in patients that are at risk of graft dislocation into the vitreous cavity as a result of minimal or absent iris-lens diaphragm. DESIGN:Interventio...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.08.043
更新日期：2011-03-01 00:00:00
abstract：PURPOSE:To determine whether a machine learning technique called Kalman filtering (KF) can accurately forecast future values of mean deviation (MD), pattern standard deviation, and intraocular pressure for patients with normal tension glaucoma (NTG). DESIGN:Development and testing of a forecasting model for glaucoma p...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2018.10.012
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:To determine if adequate intraocular levels of methotrexate are achieved after intravenous administration. METHODS:After intravenous administration, methotrexate levels were determined in the serum, the anterior chamber, and the cerebrospinal fluids of a patient with recurrent ocular lymphoma. A fluorescence p...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70444-1
更新日期：1996-04-01 00:00:00
abstract：:Subretinal neovascularization was demonstrated in a subhuman primate eye (Macaca speciosa) one year after the internal carotid injection of yeast-phase Histoplasma capsulatum. In this animal model of ocular histoplasmosis, initial injection of viable H. capsulatum results in the development of self-limiting acute mult...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(85)90790-1
更新日期：1985-08-15 00:00:00
abstract：PURPOSE:To study the effect of commonly used preservative free artificial tear, carboxymethylcellulose (CMC) 0.5% (Refresh Plus, Allergan, Irvine, California) on visual acuity in symptomatic dry eye (SDE) and asymptomatic dry eye (ADE) patients. DESIGN:Nonrandomized prospective clinical trial. METHODS:Prospective stu...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/j.ajo.2005.05.001
更新日期：2005-11-01 00:00:00
abstract：:Of 45 patients with proliferative sickle retinopathy in stages III, IV, and V, nine patients (eight with hemoglobin SC disease, one with sickle cell thalassemia) showed spontaneous regression (autoinfarction) of retinal sea fans. One mechanism involved in autoinfarction of neovascular tissue is progressive, centripeta...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90285-8
更新日期：1975-11-01 00:00:00
abstract：:We analyzed two consecutive series of cataract extractions in patients with moderate to severe myopia for the incidence of postoperative retinal detachment. One series consisted of 122 intracapsular cataract extractions without surgical loss of vitreous and the other series consisted of 151 extracapsular (phacoemulsif...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90445-8
更新日期：1984-01-01 00:00:00
abstract：PURPOSE:To highlight the challenges of postmarketing surveillance for drug-related adverse events in the practice of ophthalmology. DESIGN:A retrospective review of the medical literature and postmarketing surveillance databases. METHODS:MEDLINE literature review of sildenafil-associated or amiodarone-associated opti...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.10.005
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:To compare visual and topographic outcomes 1 year after conventional (C-CXL) vs accelerated corneal cross-linking (A-CXL) in pediatric keratoconus (KC). DESIGN:Comparative, retrospective, consecutive case series. METHODS:Patients with topography-confirmed, progressive KC and a corneal thickness of ≥400 μm at ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.08.015
更新日期：2017-11-01 00:00:00
abstract：:To evaluate the effects of two beta-adrenergic blocking agents on cardiopulmonary function, we investigated two topical ophthalmologic preparations, betaxolol 1% and timolol 0.5%, in nine patients (eight men and one woman, ranging in age from 25 to 69 years) with reactive airway disease. The randomized, double-masked,...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90450-1
更新日期：1984-01-01 00:00:00
abstract：:A 20-month-old boy with a ciliary body tumor presented with two white flocculi floating in the anterior chamber of his left eye. This material was examined by electron microscopy. Both the clinical appearance of the tumor and the ultrastructural findings suggested the diagnosis of medulloepithelioma. The flocculi cont...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90089-6
更新日期：1975-02-01 00:00:00
abstract：PURPOSE:To report an unusual, blinding inflicted eye injury in young children. DESIGN:Observational case report. METHODS:Retrospective study in an institutional clinical practice of two families in whom the probands had inferior half keratoconjunctivitis and additional signs of child abuse. RESULTS:Two unrelated inf...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.06.089
更新日期：2005-01-01 00:00:00
abstract：:A 32-year-old obese woman with hypertension and a three-year history of pseudotumor cerebri developed bilateral juxtapapillary subretinal neovascular membranes. To our knowledge, this is the first reported case of bilateral subretinal neovascular membranes complicating the course of this disease. The subretinal neovas...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(81)90282-8
更新日期：1981-03-01 00:00:00
abstract：PURPOSE:To evaluate the specificity of current definitions used to identify progressive change of the average peripapillary retinal nerve fiber layer (RNFL) thickness measurements obtained on optical coherence tomography (OCT) imaging. DESIGN:Prospective observational cohort study. METHODS:Setting: University of Cali...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.06.017
更新日期：2017-09-01 00:00:00
abstract：PURPOSE:To report on the clinical manifestations, complications, and long-term visual prognosis of patients with peripheral multifocal chorioretinitis and to search for predictors for a lower visual outcome. DESIGN:Retrospective consecutive observational case series. METHODS:setting: Institutional. PATIENT POPULATIO...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.01.005
更新日期：2015-04-01 00:00:00
