Abstract:
:A 20-month-old boy with a ciliary body tumor presented with two white flocculi floating in the anterior chamber of his left eye. This material was examined by electron microscopy. Both the clinical appearance of the tumor and the ultrastructural findings suggested the diagnosis of medulloepithelioma. The flocculi contained tumor cells forming lumina and displaying neuronal-type cilia, neurotubules, and a complex band of apical desmonosomal junctions. Since the last finding is not present in retinoblastoma rosettes in the absence of fleurette differentiation, it distinguishes medulloepithelioma from retinoblastoma. The electron microscopic diagnosis has permitted a trial period of conservative cryotherapy directed at the tumor and the associated glaucoma. The electron microscopic characteristics of the tumor favor the neuroepitheliomatous and neuroblastic differentiation of medulloepithelioma rather than ependymal differentiation.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Jakobiec FA,Howard GM,Ellsworth RM,Rosen Mdoi
10.1016/0002-9394(75)90089-6subject
Has Abstractpub_date
1975-02-01 00:00:00pages
321-9issue
2eissn
0002-9394issn
1879-1891pii
0002-9394(75)90089-6journal_volume
79pub_type
杂志文章abstract::Abnormalities in neural crest cell migration may have a role in the pathogenesis of the congenital glaucomas, with or without changes in the gonioscopic appearance of the anterior chamber angle. Neural crest cells also contribute to the bones of the face, dental papilla, cartilage, bone, and meninges; this may explain...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90643-3
更新日期:1979-09-01 00:00:00
abstract:PURPOSE:To determine whether the frequency doubling perimeter (FDP) can grade glaucomatous visual function loss in a clinically relevant manner. Sinusoidal gratings < 1 cpd that undergo counterphase flicker > 15 Hz appear to have twice as many bands of light, a phenomenon referred to as the "frequency doubling illusion...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00047-6
更新日期:1998-06-01 00:00:00
abstract::Cryotherapy was an effective modality in the treatment of basal cell carcinoma in the eyelid and periorbital area and cured 93% of the 29 lesions in 25 patients. This method was especially advantageous in patients with blood clotting disorders; those with medical contraindications to, or who refused, classical surgery...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90059-3
更新日期:1976-12-01 00:00:00
abstract::To facilitate placing pars plana infusion ports, we modified the shaft of a piece of 10-gauge tubing or of a hypodermic needle by removing the beveled tip and Luer hub, passing the tubing through the inserter sleeve, and then reattaching the tubing to the Luer hub. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(78)90251-9
更新日期:1978-09-01 00:00:00
abstract:PURPOSE:To present a large series of choroidal hemangiomas treated with proton beam irradiation and to describe the treatment outcomes. METHODS:We treated 54 eyes of 53 patients with choroidal hemangioma. The lesions consisted of 48 circumscribed hemangiomas and six diffuse hemangiomas in patients with Sturge-Weber sy...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00150-0
更新日期:1998-08-01 00:00:00
abstract:PURPOSE:To report a patient with uveal effusion and intermittent angle-closure glaucoma associated with primary pulmonary hypertension. METHODS:Observational case report. RESULTS:A 78-year-old woman with primary pulmonary hypertension noticed pain and decreased vision in her right eye. Ocular examination disclosed ex...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)02090-1
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:To determine whether higher-order aberrations can explain the monocular diplopia reported by a patient. DESIGN:Observational case report. METHODS:A patient complaining of monocular diplopia was examined with the Hartmann-Shack aberrometer to determine if the higher-order wavefront aberrations could account fo...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.12.040
更新日期:2006-06-01 00:00:00
abstract:PURPOSE:To compare optic disk size in eyes of subjects classified as normal with the eyes of subjects with open-angle glaucoma, ocular hypertension, or pseudoexfoliation syndrome in an older population-based sample. METHODS:The Blue Mountains Eye Study examined 3,654 subjects. Vertical disk diameter was measured from ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00195-6
更新日期:1999-10-01 00:00:00
abstract:PURPOSE:We present two cases with early macular holes (MH) complicated by retinoschisis and foveal detachment (RSFD). DESIGN:Case reports. CASE REPORT:A 46-year-old woman and a 70-year-old woman, both with high myopia, presented visual loss and a small MH associated with RSFD. Vitrectomy and gas tamponade were perfor...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00319-2
更新日期:2003-10-01 00:00:00
abstract:PURPOSE:To report a case of congenital superior oblique palsy with an unusually large Bielschowsky head-tilt phenomenon (BHP) and disproportional inconspicuous vertical deviation. METHODS:Case report. RESULTS:An 18-year-old woman presented with slight compensatory head tilting and a Bielschowsky head-tilt phenomenon ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00639-5
更新日期:2000-12-01 00:00:00
abstract::Using the Octopus automated perimeter, we conducted visual measurements on four separate occasions during a four-week period in six subjects with normal eyes. In 11 of 12 eyes, we found at least one point at which the threshold for light detection determined for that point showed a variance of more than 4 dB between t...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(84)90631-7
更新日期:1984-03-01 00:00:00
abstract:PURPOSE:To determine the types and incidence of caruncular lesions and to investigate the correlation between clinical and histologic diagnosis. DESIGN:Retrospective, observational case series. METHODS:Records of patients with a lesion of the caruncle that was excised and submitted to our ocular pathology department ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.04.035
更新日期:2006-09-01 00:00:00
abstract::We studied the clinical and histopathologic ocular findings in four related males with a newly recognized syndrome consisting of microphthalmos, microencephaly, mental retardation, agenesis of the corpus callosum, hypospadius, and cryptorchidism with X-linked recessive inheritance. The ocular abnormalities include mic...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75866-0
更新日期:1985-01-15 00:00:00
abstract:PURPOSE:To report refractive changes after cataract surgery and intraocular lens implantation in infants and children. METHODS:In an ongoing prospective study, the refractive errors of all patients younger than 18 years undergoing intraocular lens implantation were determined at 6 weeks, 3 months, 6 months, and 1 year...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00247-5
更新日期:1998-12-01 00:00:00
abstract:PURPOSE:To evaluate microbiota colonizing soft contact lenses (CL) in eyes with Boston type I keratoprosthesis (BKPro), and determine the prevalence of resistance to fourth-generation fluoroquinolone (FQ). DESIGN:Prospective, observational study. SUBJECTS:Patients with BKPro using CL as routine who were in postoperat...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.05.021
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:Assessment of anterior segment-optical coherence tomography angiography (AS-OCTA) to determine severity of corneal neovascularization (CoNV). DESIGN:Retrospective, cross-sectional, single-center study. METHODS:Patients of various CoNV etiologies were selected and classified into mild, moderate, and severe. Th...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.08.023
更新日期:2020-08-18 00:00:00
abstract:PURPOSE:To report on the presence of retinal pigment epithelium (RPE) humps in high myopia, and to describe the distinctive features from pathologic RPE detachments and choroidal neovascularizations (CNVs). DESIGN:Retrospective cross-sectional study. METHODS:Charts and imaging studies of highly myopic patients presen...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.07.013
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:To document and study the relationship between perimetric sensitivity and retinal thickness at the foveal and parafoveal points in eyes with macular edema associated with branch retinal vein occlusion. METHODS:A prospective study was performed using the central 10-2 Humphrey perimetry program and optical coher...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00722-4
更新日期:2001-01-01 00:00:00
abstract:UNLABELLED:To examine prospectively the efficacy and safety of photorefractive keratectomy and photoastigmatic refractive keratectomy. METHODS:We treated 645 eyes (440 patients) with a VisX Twenty/Twenty excimer laser and followed them up for 12 months. RESULTS:The percentage of eyes with myopia between -5.01 and -10...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70433-7
更新日期:1996-04-01 00:00:00
abstract::As exemplified by the collaborative Diabetic Retinopathy Study, all the appropriate techniques involved in a clinical trial-random assignment of treatment, appropriate controls, and avoidance of investigator bias-should be incorporated during the earliest testing of a new therapy for a chronic disease, for the sake of...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:
更新日期:1975-04-01 00:00:00
abstract::A 32-year-old woman developed bilateral blindness along with severe preeclampsia of pregnancy. Ophthalmoscopic examination disclosed chalky-white optic disks with only minimal changes in the retinal vasculature. After caesarean section, the preeclampsia improved, and complete return of visual acuity occurred during a ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74914-1
更新日期:1980-09-01 00:00:00
abstract:PURPOSE:To evaluate performance of optical coherence tomography (OCT) for detection of early glaucoma. DESIGN:Observational case-control study. METHODS: SETTING:University-based tertiary care center. STUDY POPULATION:One eye from 50 normals, 42 glaucoma suspects, and 59 early glaucoma patients meeting the following...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2003.09.004
更新日期:2004-02-01 00:00:00
abstract:PURPOSE:To study the clinical characteristics of microrips of the retinal pigment epithelium (RPE) in polypoidal choroidal vasculopathy (PCV). DESIGN:Retrospective case series. METHODS:For this study, we retrospectively reviewed 156 consecutive eyes of 136 patients with PCV. The lesions were examined with fluorescein...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.12.024
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:To determine the long-term outcome of glaucoma filtration surgery in preserving vision. Visual loss from progressive glaucomatous damage and from complications of surgery, both short and long term, were included. METHODS:A retrospective, community-based, longitudinal study of residents of Olmsted County, Minne...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(01)00923-0
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:To detect the prognostic factors associated with initial reattachment after primary pars plana vitrectomy (PPV) with gas tamponade for retinal detachment attributable to macular hole (MHRD). DESIGN:Retrospective, multicenter, interventional case series. METHODS:This study included 49 eyes of 48 patients with ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2008.04.022
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:To describe a simplified new technique for repositioning and attaching a suture to the haptic of a displaced posterior chamber intraocular lens (IOL). METHODS:We describe a double-knot technique for repositioning and transscleral suture fixation of a subluxed posterior chamber IOL after penetrating keratoplast...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00244-5
更新日期:1999-11-01 00:00:00
abstract::A 253.7-nm ultraviolet light with an intensity of 1,100 microW/cm2 was tested for its germicidal activity against contact lenses and storage solutions contaminated with various corneal pathogens. The exposure time necessary to reduce a concentration of organisms from 10(6)/ml to less than 10/ml was 30 seconds for Stap...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(89)90858-1
更新日期:1989-12-15 00:00:00
abstract:PURPOSE:To determine the testability of several vision and refraction tests in preschool-aged children. DESIGN:Population-based study of Chinese preschool-aged children in Singapore. METHODS:One thousand five hundred and forty-two Singaporean Chinese children aged 6 to 72 months were recruited through door-to-door sc...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.02.037
更新日期:2009-08-01 00:00:00
abstract:PURPOSE:To evaluate long-term retention rates and complications of silicone punctal plugs among dry eye patients. DESIGN:Prospective, observational cohort study. METHODS:Ninety-five silicone punctal plugs (FCI plugs; FCI Ophthalmics, Issy-les-Moulineaux Cedex, France) were placed in 93 eyes of 47 dry eye patients. Wi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.05.019
更新日期:2007-09-01 00:00:00
abstract:PURPOSE:To describe two cases of acute traumatic maculopathy using optical coherence tomography (OCT) following high-speed motor vehicle accidents. DESIGN:Case reports. METHODS:Patients were examined soon after the accident using Snellen visual acuity (VA), dilated fundus examination, and OCT. Re-examination was cond...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.09.024
更新日期:2007-02-01 00:00:00