Abstract:
:We studied the clinical and histopathologic ocular findings in four related males with a newly recognized syndrome consisting of microphthalmos, microencephaly, mental retardation, agenesis of the corpus callosum, hypospadius, and cryptorchidism with X-linked recessive inheritance. The ocular abnormalities include microphthalmos, corneal pannus and hypoplasia, cataracts, uveal hypoplasia, retinal dysplasia, optic nerve hypoplasia, and congenital blepharoptosis. In case 4, a female twin who died in utero (at 15 weeks' gestation) showed none of the ocular abnormalities.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Duker JS,Weiss JS,Siber M,Bieber FR,Albert DMdoi
10.1016/s0002-9394(14)75866-0subject
Has Abstractpub_date
1985-01-15 00:00:00pages
51-5issue
1eissn
0002-9394issn
1879-1891pii
S0002-9394(14)75866-0journal_volume
99pub_type
杂志文章abstract:PURPOSE:To assess photoreceptor integrity in patients with retinitis pigmentosa (RP) and related diseases using ultra-high resolution optical coherence tomography (UHR-OCT) and to correlate foveal photoreceptor loss with visual acuity. DESIGN:Observational case series. METHODS:Nine eyes of nine patients with RP and r...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.07.024
更新日期:2006-12-01 00:00:00
abstract::To evaluate the ability of the Friedmann visual field analyzer to determine visual threshold and the depth of visual field defects, we correlated the visual threshold determined kinetically (Goldmann perimeter) with the static threshold (Friedmann analyzer) in various parts of the central field. We found the following...
journal_title:American journal of ophthalmology
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journal_title:American journal of ophthalmology
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更新日期:2010-11-01 00:00:00
abstract:PURPOSE:To determine the incidence of Graves' ophthalmopathy. METHODS:A population-based cohort of all Olmsted County, Minnesota, residents who had ophthalmopathy associated with autoimmune thyroid disease between Jan. 1, 1976, and Dec. 31, 1990, was identified through the medical diagnostic index of the Mayo Clinic a...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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abstract:PURPOSE:To evaluate whether retinal vessel abnormalities are associated with early or late age-related macular degeneration (AMD) in adult Chinese. DESIGN:Population-based prevalence study. METHODS:The Beijing Eye Study included 4439 (83.4%) subjects of 5324 living in a rural area or urban region of Greater Beijing, ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.05.028
更新日期:2006-10-01 00:00:00
abstract::Although penetrating trauma is a well-recognized cause of uveitis, the role of nonpenetrating trauma in initiating uveitis is not defined. We analyzed the records of 496 patients seen at the uveitis clinic at our institution. Twenty-four of these 496 patients (4.8%) suspected that the cause of their intraocular inflam...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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journal_title:American journal of ophthalmology
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2012.09.031
更新日期:2013-03-01 00:00:00
abstract:PURPOSE/METHODS:By fundus photography and histopathologic examination, we documented a case of early endogenous Aspergillus endophthalmitis in a 29-year-old man after lung transplantation. RESULTS/CONCLUSIONS:The clinical and histopathologic features of this case are consistent with those of previous case reports of e...
journal_title:American journal of ophthalmology
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更新日期:1995-01-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2010-01-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1975-07-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.02.050
更新日期:2005-09-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2020.07.008
更新日期:2020-11-01 00:00:00
abstract::In 29 experiments, vascular autologous retina from the contralateral rabbit eye was implanted into corneal pockets in New Zealand white rabbits. The implants induced a neovascular growth of limbal vessels that anastomosed with the vessels of the implant in 15 of the cases. Implantation of vascular autologous iris, cho...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90116-6
更新日期:1980-02-01 00:00:00
abstract:PURPOSE:To critically evaluate the potential impact of the coronavirus disease (COVID-19) pandemic on global ophthalmology and VISION 2020. DESIGN:Perspective supplemented with epidemiologic insights from available online databases. METHODS:We extracted data from the Global Vision Database (2017) and Global Burden of...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.11.016
更新日期:2020-12-09 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(87)90420-x
更新日期:1987-09-15 00:00:00
abstract:PURPOSE:To determine whether the frequency doubling perimeter (FDP) can grade glaucomatous visual function loss in a clinically relevant manner. Sinusoidal gratings < 1 cpd that undergo counterphase flicker > 15 Hz appear to have twice as many bands of light, a phenomenon referred to as the "frequency doubling illusion...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00047-6
更新日期:1998-06-01 00:00:00
abstract:PURPOSE:To characterize the locations, circumstances, and outcomes of falls in patients with varying degrees of glaucoma. DESIGN:Prospective cohort study. METHODS:Patients with suspected or diagnosed glaucoma completed monthly calendars reporting falls. After each fall, a 30-item questionnaire was administered to det...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.04.024
更新日期:2018-08-01 00:00:00
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journal_title:American journal of ophthalmology
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doi:10.1016/j.ajo.2018.01.034
更新日期:2018-05-01 00:00:00
abstract::A 50-year-old man sustained severe head injury, including a brief loss of consciousness, in an automobile accident. Skull X-ray films disclosed a fracture of the right superior orbit. Computed tomography demonstrated pneumocephalus and extension of the fracture into the sella turcica. Perimetric testing disclosed a bi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1981-08-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2013-02-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1979-09-01 00:00:00
abstract:PURPOSE:To investigate whether use of donors predisposed by corneal collagen cross-linking (CXL) reduced myopic refractive errors for keratoconic eyes after penetrating keratoplasty (PK). DESIGN:Randomized controlled trial. METHODS:One hundred sixteen eyes of 116 patients with keratoconus from Zhongshan Ophthalmic Ce...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,随机对照试验
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更新日期:2017-12-01 00:00:00
abstract:PURPOSE:To assess the clinical outcomes of currently used refractive surgery procedures performed in 2015. DESIGN:Prospective, multicenter cohort study. METHODS:This prospective study included 15 011 eyes of 7622 consecutive patients who underwent laser in situ keratomileusis (LASIK), surface ablation, refractive len...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2017-03-01 00:00:00
abstract::Two homosexual men, 35 and 42 years old, had bilateral acute angle-closure glaucoma in association with the acquired immune deficiency syndrome. In one patient, the angle-closure attack was the initial manifestation of AIDS. Choroidal effusion with secondary anterior rotation of the ciliary body at the scleral spur ap...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1986-04-15 00:00:00
abstract::We perfused enucleated human eyes via the anterior chamber by the constant pressure technique. Infusion of human serum into the anterior chamber of enucleated human eyes for 30 minutes at 23 mm Hg pressure induced a 42% decrease in facility of outflow, which was not relieved by irrigation of the anterior chamber with ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(78)90023-5
更新日期:1978-07-01 00:00:00
abstract:PURPOSE:To assess the effects of sustained gazing on visual function of dry eye patients. DESIGN:Prospective, comparative before-and-after study. METHODS:A total of 176 patients with dry eye and 33 control subjects ≥50 years old were included. Dry eye symptomatology along and clinical parameters were assessed. Out-lo...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-02-01 00:00:00
abstract:PURPOSE:To investigate the effect of cataract surgery on the concentration of moxifloxacin in aqueous and vitreous humor after topical application. DESIGN:Prospective laboratory intervention using a rabbit model. METHODS:Following topical administration of 0.5% moxifloxacin, 60 minutes before surgery and immediately ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2004-10-01 00:00:00
abstract:PURPOSE:To evaluate and compare the recurrence rates and complications between 2 therapeutic methods for primary pterygium: subconjunctival injection of mitomycin C (MMC) 1 month before bare scleral excision and conjunctival rotational flap with intraoperative MMC use. DESIGN:Prospective, interventional, randomized cl...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,随机对照试验
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更新日期:2010-08-01 00:00:00
abstract:PURPOSE:To explore the association between the consumption of fruits and vegetables and the presence of glaucoma. DESIGN:Cross-sectional cohort study. METHODS:In a sample of 1,155 women located in multiple centers in the United States, glaucoma specialists diagnosed glaucoma in at least one eye by assessing optic ner...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2008.01.022
更新日期:2008-06-01 00:00:00