Abstract：
PURPOSE:To report on the clinical manifestations, complications, and long-term visual prognosis of patients with peripheral multifocal chorioretinitis and to search for predictors for a lower visual outcome. DESIGN:Retrospective consecutive observational case series. METHODS:setting: Institutional. PATIENT POPULATION:134 eyes in 69 patients with a minimum follow-up period of 5 years. OBSERVATION PROCEDURE:Clinical characteristics were recorded as well as the visual acuity (VA) at the onset of uveitis; after 1, 5, and 10 years; and at the end of the follow-up period. MAIN OUTCOME MEASURES:Visual acuity, clinical features and complications, required medications and surgeries. RESULTS:The majority of the patients were elderly women with chronic bilateral ocular involvement, who developed multiple ocular complications over time. Systemic sarcoidosis was present in 39% of patients. In addition to peripheral retinal lesions and vitritis, papillitis was present in 95% of cases. The major complications included macular edema (91%), cataract (93%), glaucoma (35%), and optic disc atrophy (25%). The treatment regimens included systemic corticosteroids and/or immunosuppressive drugs in 44% of patients, and 84% of patients required intraocular surgery. One third of the affected eyes developed VA <20/40 at 5-10 years of follow-up. VA at 1 year was the most important predictor of visual outcome at 5 and 10 years (P < .001). CONCLUSIONS:Peripheral multifocal chorioretinitis was associated with a high prevalence of cataract, macular edema, optic disc atrophy, and glaucoma. Despite the chronic course of the disease, multiple complications, and surgical interventions, the majority of patients achieved satisfactory long-term visual acuity.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Ossewaarde-van Norel J,Ten Dam-van Loon N,de Boer JH,Rothova Adoi
10.1016/j.ajo.2015.01.005subject
Has Abstractpub_date
2015-04-01 00:00:00pages
690-7issue
4eissn
0002-9394issn
1879-1891pii
S0002-9394(15)00009-4journal_volume
159pub_type
杂志文章abstract：PURPOSE:To identify whether and how outcomes of macular hole (MH) surgery are influenced by the extent of internal limiting membrane (ILM) peeling. DESIGN:Randomized clinical trial. METHODS:This study involved 65 eyes from 65 patients who underwent surgery for idiopathic MH. ILM was peeled with a radius of either 0.7...
journal_title：American journal of ophthalmology
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更新日期：2016-09-01 00:00:00
abstract：PURPOSE:To report a minimally symptomatic patient with bilateral carcinoid tumors metastatic to the choroid who was followed up for 42 months without any treatment. METHOD:Case report. RESULTS:A 54-year-old white man with a history of bronchial carcinoid tumor had bilateral multiple carcinoid tumors metastatic to the...
journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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abstract：PURPOSE:To report a case of neonatal orbital ganglioglioma originating from ectopic neural tissue. METHOD:Case report. RESULTS:An African-American male presented at birth with proptosis and expansion of the left orbit. A discrete soft-tissue mass was located inferolateral to the globe, which proved to be a gangliogli...
journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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更新日期：2002-07-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2018-12-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1986-07-15 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2020-02-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1986-03-15 00:00:00
abstract：:A 20-month-old boy with a ciliary body tumor presented with two white flocculi floating in the anterior chamber of his left eye. This material was examined by electron microscopy. Both the clinical appearance of the tumor and the ultrastructural findings suggested the diagnosis of medulloepithelioma. The flocculi cont...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1975-02-01 00:00:00
