Abstract:
PURPOSE:To evaluate the efficacy of hyperdry amniotic membrane (AM) patching attached using a tissue adhesive for corneal perforations and glaucoma filtering bleb leaks. DESIGN:Prospective, noncomparative, interventional case series. METHODS:Five eyes of 5 patients (glaucoma bleb leaks, 2 eyes; corneal perforations, 3 eyes) were treated with a single-layer patch of dried AM using a biological tissue adhesive. The dried AM was prepared with consecutive far-infrared rays and microwaves (hyperdry method) and was sterilized by gamma-ray irradiation. The dried AM was cut to the desired size and shape, and the tissue adhesive was applied to the amniotic epithelial side of the dried membrane. After applying the tissue adhesive, the dried membrane with glue applied then was positioned to cover the conjunctival bleb leak site or corneal perforation lesion using forceps. A therapeutic hydrogel contact lens then was installed as a bandage. RESULTS:Bleb leaks or corneal perforations were repaired successfully within 21 days in all 5 cases. There were no remarkable adverse effects, and there was no recurrence of bleb leak or corneal perforation. CONCLUSIONS:The hyperdry AM is a useful substrate, and this surgical procedure is a promising method to treat glaucoma filtering bleb leak or corneal perforation, which may result in serious vision-threatening ocular complications.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Kitagawa K,Yanagisawa S,Watanabe K,Yunoki T,Hayashi A,Okabe M,Nikaido Tdoi
10.1016/j.ajo.2009.03.030subject
Has Abstractpub_date
2009-09-01 00:00:00pages
383-9issue
3eissn
0002-9394issn
1879-1891pii
S0002-9394(09)00259-1journal_volume
148pub_type
杂志文章abstract:PURPOSE:To describe the ocular features of a patient with an interstitial deletion of chromosome 12 and to determine the molecular boundaries of the deletion. DESIGN:Observational case report and laboratory investigation. METHODS:A patient with an interstitial deletion of chromosome 12 was clinically examined for ocu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2006-03-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2007-04-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2018-12-01 00:00:00
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更新日期:2004-09-01 00:00:00
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更新日期:2011-09-01 00:00:00
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更新日期:2001-05-01 00:00:00
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更新日期:2017-01-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1997-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-02-01 00:00:00
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更新日期:2007-12-01 00:00:00
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更新日期:2000-01-01 00:00:00
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更新日期:2010-01-01 00:00:00
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更新日期:1992-05-15 00:00:00
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更新日期:2000-04-01 00:00:00
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更新日期:2003-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:1982-01-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2011-08-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1978-12-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2005-10-01 00:00:00