Spontaneous regression (autoinfarction) of proliferative sickle retinopathy.

Abstract:

:Of 45 patients with proliferative sickle retinopathy in stages III, IV, and V, nine patients (eight with hemoglobin SC disease, one with sickle cell thalassemia) showed spontaneous regression (autoinfarction) of retinal sea fans. One mechanism involved in autoinfarction of neovascular tissue is progressive, centripetal retraction of the anterior vascular arcade of the peripheral retina. In addition, vitreous traction on feeder vessels may result in sluggish blood flow and occlusion of these vessels, or may tear the sea fan completely away from its feeder vessels. In view of the many incidences of vitreous hemorrhages that occur in patients with proliferative retinopathy, however, we recommend treatment of neovascularization rather than prolonged observation.

journal_name

Am J Ophthalmol

authors

Nagpal KC,Patrianakos D,Asdourian GK,Goldberg MF,Rabb M,Jampol L

doi

10.1016/0002-9394(75)90285-8

subject

Has Abstract

pub_date

1975-11-01 00:00:00

pages

885-92

issue

5

eissn

0002-9394

issn

1879-1891

pii

0002-9394(75)90285-8

journal_volume

80

pub_type

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