Abstract：
PURPOSE:To describe a newly identified clinical entity tentatively named white dot fovea. METHODS:We examined by scanning laser ophthalmoscopy 58 eyes of 30 patients (mean age, 64 years) who had white dots in the fovea (anatomically defined as the foveola) simulating macular hole. In addition, the retinal surfaces of 30 autopsy eyes from donors aged 70 years or older were observed by scanning electron microscopy. RESULTS:White dot fovea was bilateral in 28 of 30 patients (93%). It was characterized by the presence of numerous white dots on the foveal surface distributed either diffusely or along the foveal margin, forming a gray ring. There was no subjective symptom or visual disturbance. The condition was best seen by a scanning laser ophthalmoscope using argon blue laser as the light source. The white dots numbered from 100 to 300 per eye. Each dot was approximately 5 microns in diameter. Scanning electron microscopy showed foveal granules simulating the white dots in five of 30 autopsy eyes (17%). The granules had multiple protrusions with cilia-like structures resembling glial cells. This glia-like structure seemed to be a counterpart of clinically observed white dot fovea. CONCLUSION:White dot fovea is a new, frequent, and apparently innocuous clinical entity. It merits due attention in the differential diagnosis of macular holes.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Yokotsuka K,Kishi S,Shimizu Kdoi
10.1016/s0002-9394(14)70995-xsubject
Has Abstractpub_date
1997-01-01 00:00:00pages
76-83issue
1eissn
0002-9394issn
1879-1891pii
S0002-9394(14)70995-Xjournal_volume
123pub_type
杂志文章abstract：PURPOSE:To evaluate qualitatively the structural characteristics and the associated features that antedate the occurrence of a disk hemorrhage in patients with glaucoma. METHODS:Retrospective observational case series. A total of 4018 pairs of stereoscopic optic disk images obtained over 15 years were reviewed. All ey...
journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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更新日期：2007-04-01 00:00:00
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1998-12-01 00:00:00
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journal_title：American journal of ophthalmology
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更新日期：1996-03-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
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pub_type： 临床试验,杂志文章
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更新日期：1997-02-01 00:00:00
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更新日期：2011-04-01 00:00:00
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更新日期：2014-10-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2017-11-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
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更新日期：2018-02-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1995-07-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2006-07-01 00:00:00
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pub_type： 杂志文章
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更新日期：2002-08-01 00:00:00
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journal_title：American journal of ophthalmology
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更新日期：2017-06-01 00:00:00
