Abstract：
PURPOSE:To describe the spectral-domain optical coherence tomography (SD-OCT) features of choroidal tumors imaged using enhanced depth imaging (EDI) technique. DESIGN:Prospective observational case series. METHODS:One tumor each from 23 eyes of 23 patients was included. All the patients underwent clinical fundus photography, ultrasonography, and EDI SD-OCT. Qualitative characteristics (tumor outline, reflectivity and/or shadowing of choroidal layers, and detection of inner sclera) and quantitative characteristics (measurement of maximum tumor thickness and the largest tumor diameter) were assessed. RESULTS:Patients (male=12) were categorized as: amelanotic choroidal nevus (4), melanotic choroidal nevus (9), choroidal melanoma (3), circumscribed choroidal hemangioma (3), and choroidal metastasis (4). In all cases, EDI SD-OCT was able to identify the tumor distinctly from the surrounding normal choroid. Qualitative analysis revealed: amelanotic nevi, homogenous and medium reflective band with visible choroidal vessels; melanotic nevi and choroidal melanomas, high reflective band in the anterior choroid with shadowing, and nonvisualization of choroidal vessels and inner sclera; choroidal hemangiomas, medium/low reflective band without shadowing; and choroidal metastasis, low reflective band in the deep choroid with enlargement of the suprachoroidal space. Maximum tumor diameter and thickness was measurable by EDI SD-OCT only in 10 cases that were <9.0 mm in diameter and <1.0 mm in thickness (undetectable by ultrasonography). CONCLUSIONS:It is possible to obtain cross-sectional views of a variety of choroidal tumors using EDI SD-OCT. Small choroidal tumors nondetectable by ultrasonography can be objectively measured by this technique.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Torres VL,Brugnoni N,Kaiser PK,Singh ADdoi
10.1016/j.ajo.2010.09.028subject
Has Abstractpub_date
2011-04-01 00:00:00pages
586-593.e2issue
4eissn
0002-9394issn
1879-1891pii
S0002-9394(10)00775-0journal_volume
151pub_type
杂志文章abstract：PURPOSE:To report the successful use of topical linezolid 0.2% in the treatment of gram-positive bacterial keratitis. STUDY DESIGN:Retrospective, interventional case series. METHODS:All cases of bacterial keratitis treated at the University of Illinois Eye and Ear Infirmary with topical linezolid were identified from...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.01.010
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:To determine whether the healing response of the human cornea after photoablation with a midinfrared solid-state laser was more pronounced than after excimer laser keratectomies because of the increased thermal damage in adjacent tissue. METHODS:We treated five blind human eyes with an erbium:YAG (Er:YAG) lase...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72215-9
更新日期：1995-11-01 00:00:00
abstract：:Primary oculomotor nerve synkinesis is almost always caused by an intracavernous meningioma or aneurysm. We treated a patient who had signs of primary oculomotor nerve synkinesis from an unruptured extracavernous aneurysm located at the junction of the internal carotid artery and the posterior communicating artery. Th...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72846-6
更新日期：1994-07-15 00:00:00
abstract：:Patients with chronic forms of blepharochalasis often develop eyelid deformities characterized by blepharoptosis and prolapse of the orbital fat and lacrimal gland. Some individuals have an acquired form of blepharophimosis, secondary to the dehiscence of the canthal tendons. In this late stage of the condition, the t...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(85)90009-1
更新日期：1985-04-15 00:00:00
abstract：:In several tumors of different organ sites, the amount of DNA in a cell (ploidy) is associated with malignancy. We performed DNA quantitation in 21 choroidal melanomas and compared flow cytometry with image analysis in 11 of these melanomas. We modified our preparation technique to overcome problems with pigment and c...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73592-5
更新日期：1993-03-15 00:00:00
abstract：PURPOSE:To report a method for en face imaging of the photoreceptor inner and outer segment junction by spectral-domain optical coherence tomography (SD OCT) and to describe findings in normal subjects and patients with various retinal diseases. DESIGN:Observational case series. METHODS:SD OCT images were acquired fr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.04.027
更新日期：2011-11-01 00:00:00
abstract：PURPOSE:To assess the conjunctival bacterial profiles in dry eye and their fluoroquinolone susceptibility patterns. DESIGN:Prospective, observational study. METHODS:Sixty-seven female patients with dry eye (29 with Sjögren syndrome and 38 without Sjögren syndrome) who received artificial tears were enrolled at Osaka ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.06.003
更新日期：2008-11-01 00:00:00
abstract：PURPOSE:To examine the effect of basic fibroblast growth factor on induced choriocapillaris atrophy in vivo. METHODS:Choriocapillaris atrophy was surgically induced in rabbits by a hydraulic retinal detachment followed by debridement of the retinal pigment epithelium under the detached retina. Three concentrations of ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)00921-7
更新日期：2001-07-01 00:00:00
abstract：PURPOSE:To determine whether the frequency doubling perimeter (FDP) can grade glaucomatous visual function loss in a clinically relevant manner. Sinusoidal gratings < 1 cpd that undergo counterphase flicker > 15 Hz appear to have twice as many bands of light, a phenomenon referred to as the "frequency doubling illusion...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00047-6
更新日期：1998-06-01 00:00:00
abstract：PURPOSE:To report a rare case of craniodiaphysial dysplasia (CDD) that resulted in a profound loss of vision in both eyes. DESIGN:Observational case report. METHODS:A 2-year-old girl presented with midfacial anomaly. Marked thickening and sclerosis in the calvaria and facial bones were detected on the plain x-rays, w...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.08.071
更新日期：2006-02-01 00:00:00
abstract：PURPOSE:To report a patient with persistent subepithelial corneal opacities 18 months after adenoviral keratoconjunctivitis who underwent photorefractive keratectomy for the correction of myopia. METHODS:Case report, review of medical literature, and slit-lamp photography. RESULTS:The patient underwent photorefractiv...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00224-4
更新日期：1998-12-01 00:00:00
abstract：:A 1:2000 solution of a radiomimetic alkylating agent-triethylene thiophosphoramide (thio-tepa, Lederle Laboratories) with a proven inhibitory action on proliferating vascular endothelium, was used topically as an adjunct to pterygium surgery in an attempt to decrease the incidence of recurrence. A bare-sclera techniqu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(66)90931-7
更新日期：1966-05-01 00:00:00
abstract：:Benign lateral rectus palsy developed in two adults, a 62-year-old man and a 56-year-old woman. Both were hospitalized because of headache and diplopia. Extensive laboratory and neurologic testing showed no abnormalities except leukopenia (the white blood cell count was 2,600 cells/mm3 in one patient and 3,100 cells/m...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(82)90254-9
更新日期：1982-10-01 00:00:00
abstract：:Four patients (three men, 32, 43, and 53 years old, and one 37-year-old woman) with syphilitic neuroretinitis had cerebrospinal fluid evidence of neurosyphilis. Therapy failed in one patient given penicillin G benzathine intramuscularly and it may have failed in a second patient. Another treatment failure occurred in ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(83)90268-4
更新日期：1983-04-01 00:00:00
abstract：:We studied four patients with HIV-associated optic neuropathies. One had syphilitic optic perineuritis, which responded promptly and completely to penicillin therapy. The second had cytomegalovirus papillitis and visual acuity subsequently deteriorated to no light perception. The third showed varicella zoster optic ne...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90660-0
更新日期：1989-04-15 00:00:00
abstract：PURPOSE:To determine the amount and time course of binocular visual acuity improvement during treatment of bilateral refractive amblyopia in children three to less than 10 years of age. DESIGN:Prospective, multicenter, noncomparative intervention. METHODS:One hundred and thirteen children (mean age, 5.1 years) with p...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2007.05.040
更新日期：2007-10-01 00:00:00
abstract：PURPOSE:To evaluate a new computerized segmentation technique for the quantification of intraretinal and subretinal fluid in spectral-domain optical coherence tomography (SD OCT) images of the retina. DESIGN:Prospective, cross-sectional study. METHODS:Thirty-seven B-scan images of 37 patients with exudative age-relat...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2012.07.030
更新日期：2013-02-01 00:00:00
abstract：PURPOSE:To report the presence of pseudocysts in retinal layers of eyes with geographic atrophy (GA) attributable to age-related macular degeneration (AMD) and to estimate their prevalence. DESIGN:Retrospective study. METHODS:setting: Clinical practice. patients: Consecutive patients with GA, assessed by spectral-dom...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.02.019
更新日期：2010-08-01 00:00:00
abstract：PURPOSE:To investigate the effect of posterior subtenon injections of corticosteroids on intraocular pressure in a variety of ocular diseases. METHODS:We retrospectively analyzed 202 consecutive posterior subtenon corticosteroid injections (148 of methylprednisolone acetate, 80 mg, and 54 of triamcinolone acetonide, 4...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)80085-3
更新日期：1998-02-01 00:00:00
abstract：PURPOSE:To critically assess the evidence base regarding outcomes following cataract surgery in uveitic cases. DESIGN:Systematic evidence-based review and meta-analysis. METHODS:A comprehensive search query was performed on MEDLINE, EMBASE, CINHAL, and CENTRAL databases. Relevant publications were identified by revie...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.ajo.2014.06.018
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:To report a physician survey, laboratory studies, and clinical observations of intraoperative crystallization on the surface of the intraocular lens (IOL). METHOD:We sent a survey to all ophthalmologists in the states of Wyoming, Idaho, Montana, Utah, and Colorado asking whether crystallization on the IOL surf...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00076-2
更新日期：1998-08-01 00:00:00
abstract：:We compared the intraocular pressure-decreasing effect of timolol maleate alone, acetazolamide alone, and combined timolol and acetazolamide therapy in nine patients with bilateral chronic open-angle glaucoma. Timolol decreased intraocular pressure at least as effectively as acetazolamide. The two medications together...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75631-4
更新日期：1981-12-01 00:00:00
abstract：PURPOSE:To determine the incidence and possible causes of a late recurrence of a retinal detachment (RD) in eyes with stages 4B and 5 retinopathy of prematurity (ROP), in which the retina was once reattached by lensectomy and vitrectomy. DESIGN:Retrospective, comparative case series. METHODS:The medical records of 12...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.10.006
更新日期：2009-04-01 00:00:00
abstract：PURPOSE:To report the efficacy of an aggressive systematic regimen for the treatment of acute nonarteritic central retinal artery occlusion (CRAO). METHODS:Eleven patients who had unilateral CRAO with symptoms of fewer than 48 hours' duration were treated with an aggressive stepwise systematic regimen until retinal ci...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00359-1
更新日期：1999-12-01 00:00:00
abstract：:Patients with presumed ocular histoplasmosis syndrome were typed for HLA-A, B, C, and DR antigens. It was found that 21 (81%) of 26 of the presumed ocular histoplasmosis syndrome patients with disciform macular scarring and 8 (62%) of 13 of the presumed ocular histoplasmosis syndrome patients with peripheral atrophic ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(80)90232-9
更新日期：1980-01-01 00:00:00
abstract：PURPOSE:To determine the frequencies of medical and surgical treatments in an incidence cohort of 120 patients with Graves' ophthalmopathy. METHODS:We reviewed the community medical records and administered a follow-up questionnaire. RESULTS:Of the 120 patients, 89 (74.2%) required either no therapy or only supportiv...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70585-9
更新日期：1996-02-01 00:00:00
abstract：:Normal volunteers used 1, 2, and 4% pilocarpine eyedrops, three times daily, or ocular therapeutic systems placed in the conjunctival cul-de-sac to control intraocular pressure. The systems continuously release 20 and 40 mug/hour of pilocarpine for one week. Although the amount of drug delivered to the eye from the o...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/0002-9394(75)90404-3
更新日期：1975-10-01 00:00:00
abstract：PURPOSE:Macular imaging with optical coherence tomography (OCT) measures the most critical retinal ganglion cells (RGCs) in the human eye. The goal of this perspective is to review the challenges to detection of glaucoma progression with macular OCT imaging and propose ways to enhance its performance. DESIGN:Perspecti...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.09.026
更新日期：2020-09-18 00:00:00
abstract：PURPOSE:To investigate the potential influences that affect visual acuity (VA) outcome in a clinic-based cohort of age-related macular degeneration (AMD) patients undergoing anti-vascular endothelial growth factor (anti-VEGF) treatment for choroidal neovascularization. DESIGN:Prospective interventional case series. M...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.09.013
更新日期：2012-04-01 00:00:00
abstract：PURPOSE:To report two patients with ocular burns from explosion of microwaved eggs that caused direct vision-threatening corneal damage. METHODS:The initial examination and treatment of both patients are described. RESULTS:Both patients were initially examined with severe decrease in the visual acuity of both eyes. T...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)80153-6
更新日期：1998-03-01 00:00:00
