Abstract:
PURPOSE:To evaluate qualitatively the structural characteristics and the associated features that antedate the occurrence of a disk hemorrhage in patients with glaucoma. METHODS:Retrospective observational case series. A total of 4018 pairs of stereoscopic optic disk images obtained over 15 years were reviewed. All eyes with optic disk images before the occurrence of a disk hemorrhage were enrolled. The disk images were evaluated in a masked fashion with respect to the general neural rim and peripapillary appearance. RESULTS:The optic disk characteristics and associated features that most antedate the disk hemorrhage in 33 eyes of 26 patients that had previous optic disk images for evaluation are focal neural rim notch (36%), thin sloping rim (42%), peripapillary atrophy (79%), and superior-inferior rim asymmetry (73%). In eyes with preexisting focal rim notches, all subsequent disk hemorrhages were identified at or adjacent to the notches. CONCLUSIONS:Focal rim notching may precede the occurrence of a disk hemorrhage.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Law SK,Choe R,Caprioli Jdoi
10.1016/s0002-9394(01)01009-1subject
Has Abstractpub_date
2001-09-01 00:00:00pages
411-3issue
3eissn
0002-9394issn
1879-1891pii
S0002939401010091journal_volume
132pub_type
杂志文章abstract:PURPOSE:To report a novel mutation of the CYP1B1 gene in a Japanese patient with primary infantile glaucoma. METHODS:DNA was extracted from leukocytes of six unrelated patients with primary infantile glaucoma. The coding regions of the CYP1B1 gene were amplified by polymerase chain reaction, examined by agarose gel se...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00143-9
更新日期:1999-09-01 00:00:00
abstract:PURPOSE:To review the current status of phakic intraocular lenses (IOLs), intraocular treatment of presbyopia, and IOLs that filter some blue light. DESIGN:Review of current information on the subject from numerous sources. METHODS:Medline search and Internet search engines on the topics of phakic IOLs, presbyopia or...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/j.ajo.2005.03.061
更新日期:2005-10-01 00:00:00
abstract:PURPOSE:To identify which presenting features of rhegmatogenous retinal detachment (RRD) suggest the presence of multiple retinal breaks and to ascertain relevant patterns in retinal break location. DESIGN:Observational single-center case series. METHODS:We collected data from 851 eyes undergoing surgery for RRD betw...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2013.09.011
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:To evaluate the ability of pituitary adenylate cyclase-activating polypeptide (PACAP) to induce growth of neuronal processes in cultured trigeminal ganglion cells, and to accelerate neurite outgrowth and recovery of corneal sensitivity after creation of a corneal flap in a rabbit model of laser-assisted in situ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.10.034
更新日期:2007-02-01 00:00:00
abstract:PURPOSE:To report an inter-eye difference of the ocular pulse amplitude (OPA) in a case of innominate steal syndrome, as measured by recording applanation tonometry. METHODS:OPA was measured in a 49-year-old male before and after percutaneous transluminal angioplasty of the innominate artery. RESULTS:Before dilation ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(01)01249-1
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:This study is a systematic exploration of why some patients with glaucoma continue to lose visual field long after therapeutic normalization of their increased intraocular pressures. METHODS:Three cases of glaucoma are described that had increased intraocular pressures and good initial visual fields. RESULTS:...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75421-2
更新日期:1996-05-01 00:00:00
abstract:PURPOSE:To investigate the rate of progressive visual field (VF) loss and associated factors for structural or functional progression in preperimetric open-angle glaucoma (OAG). DESIGN:Longitudinal, observational study. METHODS:We included 127 eyes of 127 preperimetric OAG patients who were treated with topical medic...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2014.10.010
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To examine if myopia is a risk factor for age-related cataract. DESIGN:Systematic review and meta-analysis. METHODS:A systematic review of the literature was performed using PubMed and Embase from their inception to March 2013 for population-based studies with data on myopia and age-related cataract, includin...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ajo.2013.06.005
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:To determine the 24-month results of patients who had pro re nata (PRN) aflibercept treatment owing to recurrent or resistant neovascular macular degeneration. DESIGN:Retrospective, interventional, consecutive case series. METHODS:Eighty-one eyes of 78 patients with resistant or multiple recurrences of intrar...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.03.038
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To report a case series of contact lens-related corneal ulcers in compliant patients with no apparent predisposing factors. DESIGN:Retrospective case series. METHODS:Charts of 70 patients with contact lens-related corneal ulcers from July 1999 to June 2002 were reviewed. Lens care hygiene and method of disinf...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00722-0
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:To evaluate the indications for and outcomes of intraocular lens (IOL) exchange at the same clinical setting over the past decade, as well as compare the efficacy and safety of anterior chamber lens (AC-IOL) and posterior chamber lens (PC-IOL) implantation for IOL exchange. DESIGN:Retrospective, nonrandomized ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.05.015
更新日期:2005-10-01 00:00:00
abstract::We performed 115 scleral-buckling procedures for primary rhegmatogenous retinal detachments in which the argon endolaser drained subretinal fluid. The laser was set at 0.80 to 1.25 W and 0.5 second; the endolaser probe was held adjacent to, but not touching, the choroid. The procedure was successful in 112 of 115 (97....
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73643-8
更新日期:1993-06-15 00:00:00
abstract:PURPOSE:To report visual outcomes after peeling of the internal limiting membrane (ILM) using a brief application of low dose indocyanine green (ICG) for macular hole repair. DESIGN:Prospective, nonrandomized interventional case series. METHODS:A consecutive series of 16 eyes of 14 patients with full-thickness macula...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.06.029
更新日期:2004-11-01 00:00:00
abstract:PURPOSE:To determine with electronic monitoring an objective measurement of adherence in two populations of subjects: those using once-daily prostaglandin analogs as sole ocular hypotensive therapy (one-drug group) and those requiring an adjunctive medicine to the prostaglandin analog (two-drug group). DESIGN:Single-s...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.06.012
更新日期:2007-10-01 00:00:00
abstract:PURPOSE:To assess the visual outcome of inferior limited macular translocation in eyes selected based on the distance from the fovea to the inferior edge of the subfoveal choroidal neovascularization. DESIGN:Interventional case series. METHODS:We performed inferior limited macular translocation in 12 consecutive eyes...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01413-7
更新日期:2002-06-01 00:00:00
abstract:PURPOSE:To investigate the role of corneal hysteresis (CH) as a risk factor for development of glaucoma. DESIGN:Prospective observational cohort study. METHODS:Two hundred and eighty-seven eyes of 199 patients suspected of having glaucoma were followed for an average of 3.9 ± 1.8 years. All eyes had normal visual fie...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.12.018
更新日期:2018-03-01 00:00:00
abstract::A 29-year-old woman had a pigmented ciliary body mass that extended through the iris into the anterior chamber. On the basis of clinical findings and ancillary diagnostic studies, the clinical diagnosis was malignant melanoma of the ciliary body. The enucleated eye showed the tumor to be composed of cells identical to...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90278-0
更新日期:1980-05-01 00:00:00
abstract:PURPOSE:To evaluate the influence of the extent of myopia on the progression rate of normal-tension glaucoma (NTG). DESIGN:Retrospective, observational case series. METHODS:One hundred forty-three eyes of 143 patients with NTG who were treated from 1994 through 2006 and followed up with standard automated perimetry w...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.12.033
更新日期:2010-05-01 00:00:00
abstract::Amyloid was identified by light and electron microscopy within corneal grafts of two male siblings from a family with lattice corneal dystrophy type 1. These deposits indicate a recurrent disease within the donor tissue, and we believe this reflects an infiltration of the grafts by genetically abnormal host corneal fi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(82)90251-3
更新日期:1982-10-01 00:00:00
abstract:PURPOSE:Patients with idiopathic nystagmus syndrome often develop an abnormal head position. A horizontal face turn can be treated with the augmented Kestenbaum procedure, while patients with a chin up or chin down position can be treated with surgery on the vertical recti and/or oblique muscles. Although rare, some pa...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.04.034
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To report angiographically documented cystoid macula edema associated with the use of each of the three newly available ocular hypotensive lipids: unoprostone, travaprost, and bimatoprost. DESIGN:Observational case series. METHODS:Retrospective review of three patients in a clinical practice who had uncontrol...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(01)01411-8
更新日期:2002-03-01 00:00:00
abstract::We used specular microscopy to investigate corneal endothelial changes after excimer laser photorefractive keratectomy. Twenty patients (26 eyes) underwent photorefractive keratectomy for the correction of myopia. The central cornea endothelium of each eye was observed preoperatively and one month postoperatively. Six...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73467-1
更新日期:1993-12-15 00:00:00
abstract:PURPOSE:To determine the incidence of elevated intraocular pressure (IOP) and secondary glaucoma in herpetic anterior uveitis (AU), owing to either herpes simplex or varicella zoster virus, by using the Standardization of Uveitis Nomenclature (SUN) criteria, and to identify risk factors for the development of glaucoma....
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.06.013
更新日期:2017-09-01 00:00:00
abstract::With a recently developed technique for quantifying the geometry of the anterior chamber in optical cross section (slit-lamp photography using the Scheimpflug principle and computer correction for the optical effects of the cornea), we studied the iris contour before and after iridotomy in six patients with narrow ant...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)76341-x
更新日期:1990-09-15 00:00:00
abstract::Cataract operations may be recommended when retinal disease is suspected but cannot be adequately diagnosed or treated because of lens opacity. We evaluated the outcome of cataract operations performed under those circumstances. We reviewed the records of 119 patients who were examined at the Wilmer Retinal Vascular C...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75793-9
更新日期:1994-10-15 00:00:00
abstract:PURPOSE:To compare tear film thickness between normal subjects and aqueous tear deficiency dry eye patients by tear interferometry. DESIGN:Prospective case-control study. METHODS:Central precorneal tear film thickness was measured noninvasively using an interference thin-film thickness measurement device (Quore MSPA1...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2010.07.019
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To report a surgical procedure for excising subfoveal neovascular membranes and translocating the fovea in an attempt to maintain the function of the sensory retina to preserve central vision, based on the technique of macular relocation. METHODS:Three patients with subfoveal neovascular membranes underwent su...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70479-9
更新日期:1996-11-01 00:00:00
abstract::A 55-year-old man had organized hemorrhage into retinoschisis that simulated malignant melanoma both clinically and with ultrasonography. The correct diagnosis was made histopathologically after enucleation. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90199-5
更新日期:1979-01-01 00:00:00
abstract::Twenty-six eyes of 25 patients with chronic open-angle glaucoma and surgical aphakia with inadequate control of intraocular pressure (IOP) despite maximal medical treatment were treated with cyclocryotherapy, according to a prospective protocol and specific technique. (Neovascular and synechial glaucoma were excluded ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)77093-x
更新日期:1978-05-01 00:00:00
abstract::We compared the intraocular pressure-decreasing effect of timolol maleate alone, acetazolamide alone, and combined timolol and acetazolamide therapy in nine patients with bilateral chronic open-angle glaucoma. Timolol decreased intraocular pressure at least as effectively as acetazolamide. The two medications together...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75631-4
更新日期:1981-12-01 00:00:00