Abstract:
PURPOSE:To determine the incidence of elevated intraocular pressure (IOP) and secondary glaucoma in herpetic anterior uveitis (AU), owing to either herpes simplex or varicella zoster virus, by using the Standardization of Uveitis Nomenclature (SUN) criteria, and to identify risk factors for the development of glaucoma. DESIGN:Retrospective observational cohort study. METHODS:Patients with herpetic AU presenting themselves between 2001 and 2013 at the ophthalmology department of the University Medical Center Groningen were included. Main outcome measures were the incidence of elevated IOP and glaucoma and risk factors for the development of glaucoma. RESULTS:Seventy-three herpetic AU patients were included. Ocular complications most commonly seen during follow-up for uveitis were elevated IOP (75%), keratitis (59%), dry eyes (34%), posterior synechiae (34%), cataract (32%), and glaucoma (15%). Glaucoma patients, in comparison to non-glaucoma patients, had a higher number of IOP peaks during their follow-up for uveitis (P < .001). The majority of patients with elevated IOP (91%) had this already at the start of the uveitis. Nineteen percent of the patients needed glaucoma surgery. CONCLUSIONS:Using the SUN criteria, our study confirmed that elevated IOP and secondary glaucoma are major complications in herpetic AU. If an elevated IOP occurred, it was usually already present at the start of a uveitis episode. A risk factor for the development of glaucoma was the number of endured IOP peaks. Future studies are needed to evaluate whether early and prolonged use of antiviral and IOP-lowering medication may prevent glaucoma.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Hoeksema L,Jansonius NM,Los LIdoi
10.1016/j.ajo.2017.06.013subject
Has Abstractpub_date
2017-09-01 00:00:00pages
55-60eissn
0002-9394issn
1879-1891pii
S0002-9394(17)30258-1journal_volume
181pub_type
杂志文章abstract:PURPOSE:To detect the abnormalities of gray matter in children with amblyopia by voxel-based morphometry (VBM). DESIGN:Prospective, nonrandomized clinical trial. METHODS:Thirteen children with amblyopia and 14 normally sighted children underwent magnetic resonance (MR) examination. The two groups were age-matched wit...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
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更新日期:2007-03-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
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更新日期:2016-12-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75431-5
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更新日期:1988-09-15 00:00:00
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更新日期:2002-06-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2016-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-12-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.06.066
更新日期:2006-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:1987-03-15 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2010-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2003-10-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73643-8
更新日期:1993-06-15 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.05.003
更新日期:2020-10-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2011.04.027
更新日期:2011-11-01 00:00:00
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更新日期:2002-02-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2012-10-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2011-08-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2003.12.012
更新日期:2004-05-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1998-04-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
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更新日期:1993-08-15 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
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更新日期:1998-11-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1979-11-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2009-08-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.06.005
更新日期:2006-11-01 00:00:00