Abstract：
PURPOSE:To describe a case series of neovascular glaucoma (NVG) caused by central retinal vein occlusion (CRVO) that was treated with intravitreal bevacizumab (IVB; Avastin). DESIGN:Retrospective interventional case series. METHODS:Six consecutive patients with NVG and a refractory, symptomatic elevation of intraocular pressure (IOP) and pronounced anterior segment congestion received IVB (1.25 mg/0.05 ml). Diode laser cyclophotocoagulation was carried out only if pressure was controlled insufficiently by topical medication. Follow-up examinations occurred at four to 16 weeks. RESULTS:IVB resulted in a marked regression of anterior segment neovascularization and relief of symptoms within 48 hours. IOP decreased substantially in three eyes; in the other three eyes, adjuvant cyclophotocoagulation was necessary. No side effects were observed. Panretinal photocoagulation (PRP) was performed as soon as feasible, five to 12 weeks after IVB treatment. CONCLUSION:IVB leads to a rapid regression of iris and angle neovascularization and should be investigated more thoroughly as an adjunct in the management of NVG.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Iliev ME,Domig D,Wolf-Schnurrbursch U,Wolf S,Sarra GMdoi
10.1016/j.ajo.2006.06.066subject
Has Abstractpub_date
2006-12-01 00:00:00pages
1054-6issue
6eissn
0002-9394issn
1879-1891pii
S0002-9394(06)00807-5journal_volume
142pub_type
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更新日期：2008-06-01 00:00:00
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pub_type： 杂志文章
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journal_title：American journal of ophthalmology
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pub_type： 杂志文章,多中心研究
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1980-02-01 00:00:00
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pub_type： 杂志文章
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更新日期：1986-01-15 00:00:00
