Intravitreal bevacizumab (Avastin) in the treatment of neovascular glaucoma.

Abstract:

PURPOSE:To describe a case series of neovascular glaucoma (NVG) caused by central retinal vein occlusion (CRVO) that was treated with intravitreal bevacizumab (IVB; Avastin). DESIGN:Retrospective interventional case series. METHODS:Six consecutive patients with NVG and a refractory, symptomatic elevation of intraocular pressure (IOP) and pronounced anterior segment congestion received IVB (1.25 mg/0.05 ml). Diode laser cyclophotocoagulation was carried out only if pressure was controlled insufficiently by topical medication. Follow-up examinations occurred at four to 16 weeks. RESULTS:IVB resulted in a marked regression of anterior segment neovascularization and relief of symptoms within 48 hours. IOP decreased substantially in three eyes; in the other three eyes, adjuvant cyclophotocoagulation was necessary. No side effects were observed. Panretinal photocoagulation (PRP) was performed as soon as feasible, five to 12 weeks after IVB treatment. CONCLUSION:IVB leads to a rapid regression of iris and angle neovascularization and should be investigated more thoroughly as an adjunct in the management of NVG.

journal_name

Am J Ophthalmol

authors

Iliev ME,Domig D,Wolf-Schnurrbursch U,Wolf S,Sarra GM

doi

10.1016/j.ajo.2006.06.066

subject

Has Abstract

pub_date

2006-12-01 00:00:00

pages

1054-6

issue

6

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(06)00807-5

journal_volume

142

pub_type

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