Abstract：
PURPOSE:To describe the clinical presentation and histologic findings in a patient with metastatic mesothelioma presenting to the ophthalmologist with nonaxial proptosis. DESIGN:Case report. METHODS:A 55-year-old man presented with a short history of progressive ocular discomfort and vertical diplopia. Clinical examination identified nonaxial proptosis. Subsequent computed tomography showed a large extraconal mass consistent with a malignant process. Three months earlier the patient had been diagnosed with pleural mesothelioma. Unfortunately, he died 3 months after his ophthalmic presentation. Postmortem examination confirmed metastatic mesothelioma in the orbital roof that was histologically identical to the primary pleural malignancy. CONCLUSION:Pleural mesothelioma can metastasize to the orbit, causing proptosis.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Gibson A,Musa F,Pearson A,Wiggins Jdoi
10.1016/j.ajo.2003.12.012subject
Has Abstractpub_date
2004-05-01 00:00:00pages
968-9issue
5eissn
0002-9394issn
1879-1891pii
S0002939403015332journal_volume
137pub_type
杂志文章abstract：PURPOSE:To compare the sensitivities of high-speed Fourier-domain optical coherence tomography (FD-OCT) and conventional time-domain (TD) OCT for the detection of clinical findings important in the management of common vitreoretinal disorders. DESIGN:Prospective, observational study. METHODS:FD-OCT scans (128 B scans...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2009.03.004
更新日期：2009-08-01 00:00:00
abstract：PURPOSE:To assess photoreceptor integrity in patients with retinitis pigmentosa (RP) and related diseases using ultra-high resolution optical coherence tomography (UHR-OCT) and to correlate foveal photoreceptor loss with visual acuity. DESIGN:Observational case series. METHODS:Nine eyes of nine patients with RP and r...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.07.024
更新日期：2006-12-01 00:00:00
abstract：:We believe axoplasmic transport alteration is the anatomic substrate for formation of drusen of the optic disk. In familial cases the cause of axoplasmic transport alteration may be related to the presence of a genetically determined, small, crowded optic nerve head. We believe these congenitally elevated nerve heads ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76658-9
更新日期：1978-01-01 00:00:00
abstract：PURPOSE:Longstanding corneal edema can lead to anterior stromal scarring that may limit visual acuity following Descemet stripping endothelial keratoplasty (DSEK). The ideal time to perform DSEK to prevent permanent changes is unclear. Our aim is to determine whether earlier DSEK is associated with improved visual outc...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2016.09.006
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:To document a branch retinal vein obstruction secondary to a congenital arteriovenous communication. METHOD:Case report of a young patient with retinal arteriovenous communication. RESULTS:A 12-year-old girl had a grade 2 retinal arteriovenous communication in her right eye. She was asymptomatic and was subse...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00103-2
更新日期：1998-09-01 00:00:00
abstract：PURPOSE:To identify whether and how outcomes of macular hole (MH) surgery are influenced by the extent of internal limiting membrane (ILM) peeling. DESIGN:Randomized clinical trial. METHODS:This study involved 65 eyes from 65 patients who underwent surgery for idiopathic MH. ILM was peeled with a radius of either 0.7...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2016.06.041
更新日期：2016-09-01 00:00:00
abstract：PURPOSE:To compare optic disk size in eyes of subjects classified as normal with the eyes of subjects with open-angle glaucoma, ocular hypertension, or pseudoexfoliation syndrome in an older population-based sample. METHODS:The Blue Mountains Eye Study examined 3,654 subjects. Vertical disk diameter was measured from ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00195-6
更新日期：1999-10-01 00:00:00
abstract：PURPOSE:To determine a correlation between foveal morphologic changes and visual outcomes in patients with resolved central serous chorioretinopathy (CSC). DESIGN:Observational case series. METHODS:We measured the outer nuclear layer (ONL) thickness at the central fovea and evaluated the integrity of the photorecepto...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2009.01.018
更新日期：2009-07-01 00:00:00
abstract：PURPOSE:To report a case of recurrent bleeding after photodynamic therapy (PDT) in an eye with polypoidal choroidal vasculopathy (PCV). DESIGN:Interventional case report. METHODS:A 73-year-old man was treated in the left eye for PCV with PDT. RESULTS:Two weeks after PDT, his left eye showed extensive subretinal hemo...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.12.002
更新日期：2006-05-01 00:00:00
abstract：:Although surgical excision, with or without adjunctive cryotherapy, is an accepted method of managing conjunctival squamous cell carcinoma, histologically verified tumor-free surgical margins cannot be assured by excision alone. We used a tissue conservation method, an adaptation of the Mohs' micrographic technique fo...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73021-1
更新日期：1994-01-15 00:00:00
abstract：PURPOSE:To identify a rapid and reliable method to detect the Glutamine 368 STOP (Q368STOP) disease-predisposing allele of the myocilin gene associated with adult onset, primary, open-angle glaucoma. METHODS:Individuals with the Q368STOP mutation of the myocilin gene were identified from a cohort of primary open-angle...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00812-6
更新日期：2001-04-01 00:00:00
abstract：:A 62-year-old woman developed a recurrent mucinous sweat gland adenocarcinoma of the eyelid. The clinical characteristics of this rare, primary adnexal neoplasm of skin in our patient were, to our knowledge, unique. The tumor mimicked a lacrimal sac tumor and had orbital extension demonstrated preoperatively by comput...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(81)90767-4
更新日期：1981-08-01 00:00:00
abstract：PURPOSE:To report refractive changes after cataract surgery and intraocular lens implantation in infants and children. METHODS:In an ongoing prospective study, the refractive errors of all patients younger than 18 years undergoing intraocular lens implantation were determined at 6 weeks, 3 months, 6 months, and 1 year...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00247-5
更新日期：1998-12-01 00:00:00
abstract：PURPOSE:In juvenile X-linked retinoschisis (XLRS), fluorescein angiography is usually unremarkable and contributes poorly to the diagnosis. However, indocyanine green (ICG) angiography features in eyes that are affected with XLRS were not yet described. DESIGN:Retrospective observational case series. METHODS:A comple...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.03.051
更新日期：2005-09-01 00:00:00
abstract：PURPOSE:To assess the relative distribution in the cornea of amyloid and (beta)ig-h3 gene product in lattice corneal dystrophy type IIIA (LCD-IIIA). METHODS:Serial sections from the cornea of a patient with LCD-IIIA were subjected to either Congo red staining or immunohistochemistry employing an antibody to (beta)ig-h...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00360-2
更新日期：1999-04-01 00:00:00
abstract：PURPOSE:To compare the prevalence of dengue maculopathy among patients hospitalized for dengue fever during a 2007 epidemic with its prevalence during the 2005 epidemic. DESIGN:Cross-sectional observational study of consecutive patients hospitalized in two general hospitals with dengue fever during the dengue epidemic...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2009.06.030
更新日期：2009-12-01 00:00:00
abstract：PURPOSE:To report a neovascular age-related macular degeneration pattern refractory to ranibizumab. DESIGN:Retrospective, observational case series. METHODS:Between March and May 2009, cases with neovascular age-related macular degeneration refractory to ranibizumab were investigated with indocyanine green angiograph...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.05.035
更新日期：2010-11-01 00:00:00
abstract：:A 5-month-old infant girl died of familial lymphohistiocytosis. The central nervous system showed widespread perivascular infiltration of the cerebral pia and arachnoid, the cerebral white matter and deep gray matter, the cerebellum, and brain stem by lymphocytes, benign appearing histiocytes, and macrophages with ery...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(76)90013-1
更新日期：1976-11-01 00:00:00
abstract：:Samples from the center of a wide-field specular micrograph adequately assessed cell density and frequency distribution of cell areas. A preliminary analysis of the spread of values indicated whether an increased sample size was required. An algorithm determined how large a sample taken from the central photograph (th...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76133-1
更新日期：1984-04-01 00:00:00
abstract：:Eight patients were treated for Pseudomonas endophthalmitis associated with the implantation of contaminated intraocular lenses. All patients showed clinical signs of infection (loss of red reflex, diminished visual acuity, and intraocular lens coagulum) and P. aeruginosa was isolated from vitreous aspirates and unuse...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90569-5
更新日期：1979-11-01 00:00:00
abstract：PURPOSE:To describe the usage patterns of pharmacological treatments for neovascular age-related macular degeneration (AMD) in Medicare fee-for-service beneficiaries. DESIGN:Retrospective review of all Medicare fee-for-service Part B claims for neovascular AMD during 2008. METHODS:Medicare beneficiaries having underg...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.11.017
更新日期：2011-05-01 00:00:00
abstract：PURPOSE:To review the current status of phakic intraocular lenses (IOLs), intraocular treatment of presbyopia, and IOLs that filter some blue light. DESIGN:Review of current information on the subject from numerous sources. METHODS:Medline search and Internet search engines on the topics of phakic IOLs, presbyopia or...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.ajo.2005.03.061
更新日期：2005-10-01 00:00:00
abstract：PURPOSE:To present a case of congenital toxoplasmosis in a newborn whose mother had a 20-year history of a chorioretinal macular scar and positive serology for toxoplasmosis. DESIGN/METHODS:Case report. SETTING/RESULTS: A 38-year-old woman who had been treated for ocular toxoplasmosis 20 years earlier delivered a newb...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00191-0
更新日期：2003-08-01 00:00:00
abstract：PURPOSE:To evaluate performance of optical coherence tomography (OCT) for detection of early glaucoma. DESIGN:Observational case-control study. METHODS: SETTING:University-based tertiary care center. STUDY POPULATION:One eye from 50 normals, 42 glaucoma suspects, and 59 early glaucoma patients meeting the following...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2003.09.004
更新日期：2004-02-01 00:00:00
abstract：PURPOSE:To report a young girl with spontaneous separation of an idiopathic epiretinal membrane and notable visual recovery. METHOD:Case report. RESULT:A 12-year-old girl had spontaneous improvement in visual acuity of the left eye from 20/100 to 20/40 attributable to spontaneous peeling of an idiopathic epiretinal m...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00021-5
更新日期：1999-06-01 00:00:00
abstract：PURPOSE:To investigate thermal changes produced by a chandelier fiber probe (CFP). DESIGN:Interventional single case report and laboratory investigation. METHODS:When CFP was used for 25-gauge vitrectomy, an abnormal odor was emitted, and the CFP was instantly removed. To investigate this incident, the thermal change...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.07.049
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:To assess the long-term stability of sutured scleral-fixated posterior chamber intraocular lenses (PCIOLs) performed in combination with pars plana vitrectomy. DESIGN:Retrospective, consecutive, interventional case series. METHODS:Retrospective single-surgeon study of 118 eyes of 111 patients seen at Retina C...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.01.034
更新日期：2018-05-01 00:00:00
abstract：PURPOSE:To report a patient who was initially examined with optic tract syndrome caused by a focal metastasis to the lateral geniculate body and optic tract. METHOD:Case report. RESULTS:A 44-year-old woman with metastatic breast cancer was initially examined with normal central visual acuity, afferent pupillary defec...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)80251-7
更新日期：1998-01-01 00:00:00
abstract：:We studied four patients with HIV-associated optic neuropathies. One had syphilitic optic perineuritis, which responded promptly and completely to penicillin therapy. The second had cytomegalovirus papillitis and visual acuity subsequently deteriorated to no light perception. The third showed varicella zoster optic ne...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90660-0
更新日期：1989-04-15 00:00:00
abstract：PURPOSE:To correlate the anatomic features of the macula with functional parameters like location and stability of fixation in patients with neovascular age-related macular degeneration treated with intravitreal ranibizumab injections. DESIGN:Retrospective analysis. METHODS:The location and stability of fixation were...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2011.08.034
更新日期：2012-03-01 00:00:00
