Abstract:
PURPOSE:To determine a correlation between foveal morphologic changes and visual outcomes in patients with resolved central serous chorioretinopathy (CSC). DESIGN:Observational case series. METHODS:We measured the outer nuclear layer (ONL) thickness at the central fovea and evaluated the integrity of the photoreceptor inner and outer segment junction (IS/OS) using spectral-domain optical coherence tomography in 67 eyes (65 patients) with resolved CSC. The patients were divided into 2 groups: group A included 24 eyes (23 patients) with best-corrected visual acuity (BCVA) of less than 1.0, and group B included 43 eyes (42 patients) with BCVA of 1.0 or better. Group C was comprised of normal control eyes (10 volunteers). We also determined a correlation between the ONL thickness and BCVA. RESULTS:The average ONL thicknesses at the central fovea in groups A, B, and C were 74.6 microm, 103.2 microm, and 124.9 microm, respectively. The average ONL thickness at the central fovea in group A was significantly (P < .001) thinner than that in group B, and that in group B was significantly (P = .0014) thinner than that in group C. The ONL thickness was correlated with the BCVA (r(s) = 0.59; P < .001). Discontinuity of the IS/OS line was observed in 22 eyes (91.7%) in group A, in 9 eyes (20.9%) in group B, and in no eyes in group C, with the difference between groups A and B reaching significance (P < .001). CONCLUSIONS:The ONL thickness is positively correlated with the BCVA in resolved CSC. Discontinuity of the IS/OS line was prevalent in eyes with thinner ONL and lower BCVA.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Matsumoto H,Sato T,Kishi Sdoi
10.1016/j.ajo.2009.01.018subject
Has Abstractpub_date
2009-07-01 00:00:00pages
105-10.e1issue
1eissn
0002-9394issn
1879-1891pii
S0002-9394(09)00068-3journal_volume
148pub_type
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更新日期:2012-04-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2007-01-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2017-10-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2001-02-01 00:00:00
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