Oprelvekin-associated bilateral optic disk edema.

Abstract:

PURPOSE:To report a case of bilateral optic disk edema in a patient taking oprelvekin for radioimmunotherapy-induced thrombocytopenia. DESIGN:Observational case report. METHODS:A 38-year-old man with a history of relapsed non-Hodgkins follicular lymphoma complained of bilateral loss of vision following oprelvekin therapy for thrombocytopenia. RESULTS:Funduscopic examination demonstrated bilateral optic disk edema with exudates inferotemporal to the right nerve. The results of magnetic resonance imaging of the brain and orbits and lumbar puncture were normal. The disk edema resolved with discontinuation of oprelvekin therapy. CONCLUSIONS:Oprelvekin therapy may be associated with bilateral optic disk edema. This has been shown to be reversible in a primate model.

journal_name

Am J Ophthalmol

authors

Peterson DC,Inwards DJ,Younge BR

doi

10.1016/j.ajo.2004.07.055

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

367-8

issue

2

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(04)00945-6

journal_volume

139

pub_type

杂志文章
  • Prevalence of Antiretinal Antibodies in Acute Zonal Occult Outer Retinopathy: A Comprehensive Review of 25 Cases.

    abstract:PURPOSE:To perform a comprehensive review and to investigate the presence and role of autoimmune antibodies in 25 cases of acute zonal occult outer retinopathy (AZOOR) identified using the classification originally proposed by J. Donald Gass. DESIGN:Observational case series. METHODS:Setting: Institutional. STUDY PO...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2016.12.001

    authors: Qian CX,Wang A,DeMill DL,Jayasundera T,Branham K,Abalem MF,Khan N,Heckenlively JR

    更新日期:2017-04-01 00:00:00

  • Lymphocyte subpopulations before therapy in patients with uveal malignant melanoma.

    abstract::T-cell and B-cell lymphocyte subpopulations, monocytes, granulocytes, and immunoglobulin receptors were measured with monoclonal antibodies and flow cytometric techniques in the peripheral blood of 266 patients with posterior uveal melanoma before therapy. Statistically significant differences were found in T-helper/i...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(86)90587-8

    authors: Flynn K,Felberg NT,Koegel A,Hager R,Shields JA,Augsburger JJ,Donoso LA

    更新日期:1986-02-15 00:00:00

  • Cancer-associated retinopathy associated with invasive thymoma.

    abstract:PURPOSE:To report a case of cancer-associated retinopathy associated with invasive thymoma. DESIGN:Interventional case report. METHOD:A 41-year-old Japanese woman was observed between February 1998 and May 2001. Ophthalmologic examinations and systemic examinations were performed. The patient received treatment inclu...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(02)01598-2

    authors: Katsuta H,Okada M,Nakauchi T,Takahashi Y,Yamao S,Uchida S

    更新日期:2002-09-01 00:00:00

  • A method to confirm correct orientation of descemet membrane during descemet membrane endothelial keratoplasty.

    abstract:PURPOSE:Descemet membrane endothelial keratoplasty is a new technique for the replacement of diseased corneal endothelium with healthy donor endothelium. During this procedure, manipulation of the donor endothelium-Descemet membrane layer within the recipient anterior chamber can be associated with loss of the correct ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2010.01.005

    authors: Bachmann BO,Laaser K,Cursiefen C,Kruse FE

    更新日期:2010-06-01 00:00:00

  • Distribution of central corneal thickness and its association with intraocular pressure: The Rotterdam Study.

    abstract:PURPOSE:To perform a cross-sectional study on the distribution of central corneal thickness and its association with intraocular pressure in an elderly population. METHODS:We measured central corneal thickness and intraocular pressure in 395 subjects (352 control subjects, 13 patients with ocular hypertension, and 30 ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)71125-0

    authors: Wolfs RC,Klaver CC,Vingerling JR,Grobbee DE,Hofman A,de Jong PT

    更新日期:1997-06-01 00:00:00

  • The pattern and distribution of retinal breaks in eyes with rhegmatogenous retinal detachment.

    abstract:PURPOSE:To identify which presenting features of rhegmatogenous retinal detachment (RRD) suggest the presence of multiple retinal breaks and to ascertain relevant patterns in retinal break location. DESIGN:Observational single-center case series. METHODS:We collected data from 851 eyes undergoing surgery for RRD betw...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2013.09.011

    authors: Shunmugam M,Shah AN,Hysi PG,Williamson TH

    更新日期:2014-01-01 00:00:00

  • Persistently Vitreous Culture-Positive Exogenous Fungal Endophthalmitis.

    abstract:PURPOSE:To report the clinical settings, microbiological isolates, and best-corrected visual acuities (BCVA) of patients with persistently culture-positive exogenous fungal endophthlamitis. DESIGN:Retrospective consecutive case series. METHODS:Setting: Tertiary referral center. PATIENT POPULATION:Sixteen eyes of 16 ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2016.09.014

    authors: Leung EH,Kuriyan AE,Flynn HW Jr,Relhan N,Huang LC,Miller D

    更新日期:2016-12-01 00:00:00

  • Systemic diagnostic testing in patients with apparently isolated uveal coloboma.

    abstract:PURPOSE:To investigate the frequency and types of systemic findings in patients with apparently isolated uveal coloboma. DESIGN:Cross-sectional observational study. METHODS:setting: Single-center ophthalmic genetics clinic. study population: Ninety-nine patients with uveal coloboma seen at the National Eye Institute....

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2013.06.037

    authors: Huynh N,Blain D,Glaser T,Doss EL,Zein WM,Lang DM,Baker EH,Hill S,Brewer CC,Kopp JB,Bardakjian TM,Maumenee IH,Bateman BJ,Brooks BP

    更新日期:2013-12-01 00:00:00

  • Clinicopathologic study of ocular trauma in eyes with intraocular lenses.

    abstract::Data on 41 cases (37 intraocular lenses and four globes) of intraocular lenses explanted or expulsed after ocular trauma were retrieved from over 5,000 intraocular lenses and 1,200 globes. The age of the male and female donors varied significantly (male, 64.4 +/- 13.1 years; female, 75.5 +/- 12.6 years; P = .0334). Tw...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)73012-0

    authors: Assia EI,Blotnick CA,Powers TP,Legler UF,Apple DJ

    更新日期:1994-01-15 00:00:00

  • Ahmed valve implantation with adjunctive mitomycin C and 5-fluorouracil: long-term outcomes.

    abstract:PURPOSE:To evaluate long-term outcomes after Ahmed valve implantation in patients with glaucoma when using adjunctive intraoperative mitomycin C (MMC) and postoperative 5-fluorouracil (5-FU). DESIGN:Retrospective, interventional, consecutive case series. METHODS:A consecutive series of eyes undergoing Ahmed valve imp...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2008.04.008

    authors: Alvarado JA,Hollander DA,Juster RP,Lee LC

    更新日期:2008-08-01 00:00:00

  • Hypothermia of 8 degrees C protects cultured retinal pigment epithelial cells and retinal ganglion cells against trypan blue toxicity.

    abstract:PURPOSE:To determine whether hypothermia of 8 degrees C can protect cultured human retinal pigment epithelial (ARPE-19) cells and rat retinal ganglion cells (RGC-5) against trypan blue (TB) toxicity. DESIGN:Laboratory investigation. METHODS:ARPE-19 cells and RGC-5 were exposed to balanced salt solution as controls, a...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2005.10.054

    authors: Kunikata H,Abe T,Murata H,Sagara Y,Wakusawa R,Sato H,Yoshida M,Fuse N,Tamai M

    更新日期:2006-04-01 00:00:00

  • Secretory component in human ocular tissues.

    abstract::Lacrimal tissue and accessory lacrimal tissue from seven autopsy cases, lacrimal tissue from three patients undergoing orbital exploration, and biopsy specimens from conjunctiva of 14 subjects were examined for the presence and distribution of secretory component by three anti-secretory-component antisera. Secretory c...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(80)90004-5

    authors: Allansmith MR,Gillette TE

    更新日期:1980-03-01 00:00:00

  • Visual Outcomes in Presumed Congenital Foveal Toxoplasmosis.

    abstract:PURPOSE:Congenital macular lesions attributed to toxoplasmosis may limit potential visual acuity. The appearance and location of these scars may cause physicians to overlook associated amblyopia. This study reviews the visual outcomes and benefits of amblyopia therapy in children with foveal toxoplasmosis scars. DESIG...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2020.01.034

    authors: Reynolds MMM,Chisholm SAM,Schroeder R,Lueder GT

    更新日期:2020-06-01 00:00:00

  • In Vivo Confocal Microscopy Morphologic Features and Cyst Density in Acanthamoeba Keratitis.

    abstract:PURPOSE:To correlate in vivo confocal microscopy morphologic features (IVCM-MF) and Acanthamoeba cyst density (ACD) with final best-corrected visual acuity (BCVA) in Acanthamoeba keratitis (AK). DESIGN:Retrospective cohort study. METHODS:Patient demographics, treatment outcome, and corresponding IVCM-MF performed at ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2020.03.048

    authors: Chopra R,Mulholland PJ,Hau SC

    更新日期:2020-09-01 00:00:00

  • Birdshot Retinochoroidopathy: Prognostic Factors of Long-term Visual Outcome.

    abstract:PURPOSE:To determine the prognostic factors of long-term visual outcome in birdshot retinochoroidopathy (BRC). METHODS:Design: Retrospective case series. Study Population: Successive HLA-A29+ BRC patients whose latest visit was between May and August 2013 at a single tertiary center (Pitié-Salpétrière Hospital, Paris)...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2016.08.007

    authors: Touhami S,Fardeau C,Vanier A,Zambrowski O,Steinborn R,Simon C,Tezenas du Montcel S,Bodaghi B,Lehoang P

    更新日期:2016-10-01 00:00:00

  • A simplified technique of orbital decompression for severe retrobulbar hemorrhage.

    abstract::Severe retrobulbar hemorrhage may occur as a complication of a retrobulbar injection or from blunt or sharp injury to the orbit during an orbital or periorbital operation. When the patient with a severe retrobulbar hemorrhage does not respond to intermittent ocular massage, or paracentesis, or a lateral canthotomy, pr...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)71740-4

    authors: Liu D

    更新日期:1993-07-15 00:00:00

  • Spontaneous regression (autoinfarction) of proliferative sickle retinopathy.

    abstract::Of 45 patients with proliferative sickle retinopathy in stages III, IV, and V, nine patients (eight with hemoglobin SC disease, one with sickle cell thalassemia) showed spontaneous regression (autoinfarction) of retinal sea fans. One mechanism involved in autoinfarction of neovascular tissue is progressive, centripeta...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(75)90285-8

    authors: Nagpal KC,Patrianakos D,Asdourian GK,Goldberg MF,Rabb M,Jampol L

    更新日期:1975-11-01 00:00:00

  • Spontaneous resolution of foveal detachments and macular breaks.

    abstract:PURPOSE:To evaluate the mechanism of spontaneous resolution of foveal detachments and idiopathic macular breaks. METHODS:We reviewed the records of 139 consecutive eyes (94 patients) with either a foveal detachment or a macular break in patients who were examined between 1989 and 1992. There were 26 men and 68 women (...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)72730-8

    authors: Kakehashi A,Schepens CL,Akiba J,Hikichi T,Trempe CL

    更新日期:1995-12-01 00:00:00

  • Blepharochalasis syndrome.

    abstract::Patients with chronic forms of blepharochalasis often develop eyelid deformities characterized by blepharoptosis and prolapse of the orbital fat and lacrimal gland. Some individuals have an acquired form of blepharophimosis, secondary to the dehiscence of the canthal tendons. In this late stage of the condition, the t...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(85)90009-1

    authors: Custer PL,Tenzel RR,Kowalczyk AP

    更新日期:1985-04-15 00:00:00

  • Metastatic mesothelioma presenting with proptosis.

    abstract:PURPOSE:To describe the clinical presentation and histologic findings in a patient with metastatic mesothelioma presenting to the ophthalmologist with nonaxial proptosis. DESIGN:Case report. METHODS:A 55-year-old man presented with a short history of progressive ocular discomfort and vertical diplopia. Clinical exami...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2003.12.012

    authors: Gibson A,Musa F,Pearson A,Wiggins J

    更新日期:2004-05-01 00:00:00

  • Corneal biopsy in the diagnosis of keratomycosis.

    abstract::In two patients, a 55-year-old man and a 49-year-old man, who had fungal keratitis initially undiagnosed by corneal scrapings the condition was successfully diagnosed by corneal biopsy. We compared corneal biopsy specimens and corneal scraping in the diagnosis of keratomycosis in rabbits with experimental bilateral fu...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(86)90821-4

    authors: Ishibashi Y,Kaufman HE

    更新日期:1986-03-15 00:00:00

  • Balloon catheter dilation for treatment of persistent nasolacrimal duct obstruction.

    abstract:PURPOSE:To report the outcome of balloon catheter dilation of the lacrimal duct for treatment of children with persistent nasolacrimal duct obstruction after previous surgery. DESIGN:Interventional case series. METHODS:Thirty-two consecutive children with a history of persistent nasolacrimal duct obstruction followin...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(01)01403-9

    authors: Lueder GT

    更新日期:2002-03-01 00:00:00

  • Parinaud's oculoglandular syndrome attributable to an encounter with a wild rabbit.

    abstract:PURPOSE:To describe the clinical and histopathologic findings in a patient with Parinaud's oculoglandular syndrome attributable to Francisella tularensis obtained from an encounter with a wild baby rabbit. METHODS:In an 18-year-old man, the clinical course, laboratory findings, and histopathologic findings are describ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(00)00954-5

    authors: Thompson S,Omphroy L,Oetting T

    更新日期:2001-02-01 00:00:00

  • Accommodative intraocular lens tilting.

    abstract:PURPOSE:To report an unusual complication of accommodative intraocular lens (IOL) implantation after clear lens extraction for hyperopia correction. DESIGN:Observational case report. METHOD:A 48-year-old woman underwent clear lens exchange for the correction of moderate hyperopia. A Crystalens Model AT-45 Accommodati...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2005.02.040

    authors: Cazal J,Lavin-Dapena C,Marín J,Vergés C

    更新日期:2005-08-01 00:00:00

  • The impact of contact lens wear and visual display terminal work on ocular surface and tear functions in office workers.

    abstract:PURPOSE:To evaluate the effect of contact lens (CL) wear and visual display terminal (VDT) work on the ocular surface and tear functions. DESIGN:Prospective case-control study. METHODS:Sixty-nine CL wearers (45 women and 24 men; mean age, 35.2 ± 7.3 years), and 102 age- and sex-matched non-CL wearers were enrolled in...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2011.05.025

    authors: Kojima T,Ibrahim OM,Wakamatsu T,Tsuyama A,Ogawa J,Matsumoto Y,Dogru M,Tsubota K

    更新日期:2011-12-01 00:00:00

  • Autosomal recessive pericentral pigmentary retinopathy.

    abstract::A brother and sister, born to consanguineous parents, had pigmentary retinopathy in a pericentral distribution. The retinopathy was noted in infancy when the siblings were examined for strabismus. The optic disks, maculae, and retinal vessels were normal. There was mild reduction in amplitude of both scotopic and phot...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(88)90584-3

    authors: Traboulsi EI,O'Neill JF,Maumenee IH

    更新日期:1988-11-15 00:00:00

  • Limiting photoreceptor death and deconstruction during experimental retinal detachment: the value of oxygen supplementation.

    abstract:PURPOSE:To assess the role of hypoxia in causing the death and deconstruction of photoreceptors in detached retinas and the effectiveness of supplemental oxygen in limiting such damage. METHODS:Retinal detachment was induced surgically in the right eye of each of 10 cats. The cats were allowed to survive surgery for 3...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(99)00104-x

    authors: Mervin K,Valter K,Maslim J,Lewis G,Fisher S,Stone J

    更新日期:1999-08-01 00:00:00

  • Topical tetracycline and rifampicin therapy of endemic trachoma in Tunisia.

    abstract::A controlled chemotherapy trial of trachoma was carried out in a Tunisian oasis among schoolchildren with active disease. We compared 1% tetracycline ointment (79 patients) or 1% rifampicin ointment (76 patients) with 5% boric acid ointment (79 patients). Medications were administered twice daily, six days a week, for...

    journal_title:American journal of ophthalmology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-9394(75)90740-0

    authors: Dawson CR,Hoshiwara I,Daghfous T,Messadi M,Vastine DW,Schachter J

    更新日期:1975-05-01 00:00:00

  • Basal cell carcinoma of the eyelid as an indicator of multifocal malignancy.

    abstract::Of 30 consecutive patients with ocular adnexal basal cell carcinoma, 18 (60%) had at least one additional unsuspected foci of basal cell carcinoma. The patients most likely to have additional basal cell skin cancer were women, those with previous basal cell carcinoma, and those whose eyelid lesions were recurrent, loc...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(82)90002-2

    authors: Wesley RE,Collins JW

    更新日期:1982-11-01 00:00:00

  • Stroke Risk and Risk Factors in Patients With Central Retinal Artery Occlusion.

    abstract:PURPOSE:Central retinal artery occlusion (CRAO) is mechanistically similar to a stroke. Current guidelines recommend a standardized and systematic evaluation of risk factors for patients who have had a stroke. This study evaluates the yield of this evaluation in patients with CRAO and frequency of stroke in this popula...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2018.08.027

    authors: Lavin P,Patrylo M,Hollar M,Espaillat KB,Kirshner H,Schrag M

    更新日期:2018-12-01 00:00:00