Secretory component in human ocular tissues.

Abstract:

:Lacrimal tissue and accessory lacrimal tissue from seven autopsy cases, lacrimal tissue from three patients undergoing orbital exploration, and biopsy specimens from conjunctiva of 14 subjects were examined for the presence and distribution of secretory component by three anti-secretory-component antisera. Secretory component was present in all lacrimal and accessory lacrimal tissues but in no other ocular tissues. Over 60% of acinar cells stained for secretory component; about 5% of acinar cells stained brightly; about 30% of tubular cells stained brightly. Main and accessory lacrimal tissues appeared identical in their staining patterns. We concluded that the main sites of synthesis of secretory IgA in human ocular tissues are the lacrimal and accessory lacrimal tissues.

journal_name

Am J Ophthalmol

authors

Allansmith MR,Gillette TE

doi

10.1016/0002-9394(80)90004-5

subject

Has Abstract

pub_date

1980-03-01 00:00:00

pages

353-61

issue

3

eissn

0002-9394

issn

1879-1891

pii

0002-9394(80)90004-5

journal_volume

89

pub_type

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