Abstract:
PURPOSE:To report a case of recurrent bleeding after photodynamic therapy (PDT) in an eye with polypoidal choroidal vasculopathy (PCV). DESIGN:Interventional case report. METHODS:A 73-year-old man was treated in the left eye for PCV with PDT. RESULTS:Two weeks after PDT, his left eye showed extensive subretinal hemorrhage, with a slight vision loss. Three months after PDT, subretinal hemorrhage was almost absorbed. He received a second session of PDT to the remaining choroidal neovascularization. Two weeks thereafter, his left eye showed massive suprachoroidal hemorrhage with further vision loss. One month after the second PDT, visual acuity was decreased to no light perception as a result of massive vitreous hemorrhage. Although the patient underwent pars plana vitrectomy, visual acuity in the left eye remained hand motion as a result of massive suprachoroidal hemorrhage. CONCLUSIONS:Ophthalmologists and patients should be aware of the risk of massive bleeding after PDT in eyes with PCV.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Ojima Y,Tsujikawa A,Otani A,Hirami Y,Aikawa H,Yoshimura Ndoi
10.1016/j.ajo.2005.12.002subject
Has Abstractpub_date
2006-05-01 00:00:00pages
958-60issue
5eissn
0002-9394issn
1879-1891pii
S0002-9394(05)01272-9journal_volume
141pub_type
杂志文章abstract:PURPOSE:To assess the risk of diabetic retinopathy (DR) in children with type 1 diabetes mellitus (T1DM) diagnosed at a very early age. DESIGN:Observational case series. METHODS:The records of 51 patients were identified through the diabetes database of the Division of Pediatric Endocrinology and Metabolism at Washin...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.05.023
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:To investigate the structure-function relationship between optical coherence tomography (OCT) macular retinal and peripapillary nerve fiber layer (NFL) thickness and automated visual field (VF) findings. DESIGN:Cross-sectional observational study. METHODS:Retrospective institutional study where 150 consecutiv...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.03.019
更新日期:2004-08-01 00:00:00
abstract:PURPOSE:To describe a modified technique of haptic externalization during repositioning of dislocated posterior chamber lens implants, which facilitates placement of scleral fixation sutures around the haptic for implant stabilization. METHODS:We describe a technique of repositioning a dislocated posterior chamber imp...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00650-4
更新日期:2001-01-01 00:00:00
abstract::Glycogen, adenosine triphosphate, and hydration were measured in rabbit corneal epithelium to determine whether the corneal epithelium glycogen decrease, increase in epithelial hydration, and decrease in epithelial adenosine triphosphate stores, seen as a result of contact lens wear, were secondary only to anoxia or m...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90884-3
更新日期:1975-07-01 00:00:00
abstract:OBJECTIVE:To elucidate molecular risk factors for posterior segment uveitis using a functional genomics approach. DESIGN:Genetic association cohort study. METHODS:Setting: Single-center study at an academic referral center. STUDY POPULATION:164 patients with clinically diagnosed uveitis of the posterior segment. MA...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.07.021
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To assess the efficacy of intravitreous fomivirsen sodium, an antisense oligonucleotide, for newly diagnosed peripheral cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS). DESIGN:Randomized treatment intervention clinical trial. METHODS:A multicenter, prospective, and r...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0002-9394(02)01327-2
更新日期:2002-04-01 00:00:00
abstract:PURPOSE:To correlate visual acuity measured with the Optec 800 to the gold-standard Early Treatment Diabetic Retinopathy Study (ETDRS) chart. DESIGN:Prospective, cross-sectional study. METHODS:Forty patients of the Vanderbilt Eye Institute agreed to undergo visual acuity testing. Five patients were excluded because o...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ajo.2006.09.053
更新日期:2007-03-01 00:00:00
abstract:PURPOSE:To investigate intraocular concentrations and pharmacokinetics of ranibizumab after a single intravitreal injection in humans. DESIGN:Prospective, noncomparative, interventional case series. METHODS:We included 18 nonvitrectomized eyes of 18 patients (age range, 61-85 years) that were diagnosed with both clin...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2012.03.047
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To report a physician survey, laboratory studies, and clinical observations of intraoperative crystallization on the surface of the intraocular lens (IOL). METHOD:We sent a survey to all ophthalmologists in the states of Wyoming, Idaho, Montana, Utah, and Colorado asking whether crystallization on the IOL surf...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00076-2
更新日期:1998-08-01 00:00:00
abstract:PURPOSE:To determine the relationship between quantitative nerve fiber layer measurements and visual field testing in patients with large cup-to-disk ratios. METHODS:Seventy-six patients with vertical cup-to-disk ratios by contour of at least 0.8 on stereoscopic photographs and 50 normal subjects were included. One ey...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-9394(01)01107-2
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:To define the epidemiology of severe ocular trauma in Singapore. METHODS:A population-based incidence study involving all Singapore citizens and residents. Two government-administered databases were used to capture information on severe ocular trauma in Singapore. The national hospital discharge database provi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00167-1
更新日期:1999-09-01 00:00:00
abstract:PURPOSE:To determine the prognostic factors of long-term visual outcome in birdshot retinochoroidopathy (BRC). METHODS:Design: Retrospective case series. Study Population: Successive HLA-A29+ BRC patients whose latest visit was between May and August 2013 at a single tertiary center (Pitié-Salpétrière Hospital, Paris)...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.08.007
更新日期:2016-10-01 00:00:00
abstract::We studied the ultrastructure of the four types of dysplastic rosettes and compared them with retinoblastoma rosettes. Dysplastic rosettes have morphologic characteristics intermediate between the normal photoreceptor layer and retino-blastoma rosettes; Müller cells contribute to the formation of dysplastic but not ne...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)77107-7
更新日期:1978-05-01 00:00:00
abstract:PURPOSE:To assess the long-term stability of sutured scleral-fixated posterior chamber intraocular lenses (PCIOLs) performed in combination with pars plana vitrectomy. DESIGN:Retrospective, consecutive, interventional case series. METHODS:Retrospective single-surgeon study of 118 eyes of 111 patients seen at Retina C...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.01.034
更新日期:2018-05-01 00:00:00
abstract::A consecutive group of 67 patients (70 eyes) with senile cataract underwent extracapsular cataract extraction and implantation of a Shearing posterior chamber intraocular lens. After two years of follow-up, there was an 11% +/- 2% decrease in central cell density (P less than .001), a 20% +/- 2% decrease in superior c...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(83)90068-5
更新日期:1983-06-01 00:00:00
abstract:PURPOSE:To investigate the imaging capabilities of anterior segment optical coherence tomography (AS OCT) in microbial keratitis and to assess whether measurements of the quantitative parameters, infiltrate thickness and corneal thickness, were possible. DESIGN:Prospective, noncomparative, observational case series. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2008.05.030
更新日期:2008-10-01 00:00:00
abstract::Using correlative microscopy and plant lectins conjugated to fluorescent dyes, we studied two human corneal specimens obtained 66 and 70 months after radial keratotomy. In one case a second radial keratotomy had been performed 11 months before we obtained the corneal specimen, which allowed us to compare wounds 11 and...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)77767-0
更新日期:1987-03-15 00:00:00
abstract::A 7-year-old boy with acute lymphocytic leukemia developed iris infiltration, blood-streaked hypopyon, and high intraocular pressure. A diagnostic anterior chamber paracentesis was performed, which provided a cytologic diagnosis. The aspirate was studied by both the millipore filter technique with Papanicolaou stain a...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90112-9
更新日期:1980-02-01 00:00:00
abstract::Normal volunteers used 1, 2, and 4% pilocarpine eyedrops, three times daily, or ocular therapeutic systems placed in the conjunctival cul-de-sac to control intraocular pressure. The systems continuously release 20 and 40 mug/hour of pilocarpine for one week. Although the amount of drug delivered to the eye from the o...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/0002-9394(75)90404-3
更新日期:1975-10-01 00:00:00
abstract:PURPOSE:To describe the ultrasound biomicroscopic features of eyes with aniridia. DESIGN:Observational case series. METHODS:Nineteen eyes of 10 patients with aniridia (six males and four females) ranging in age from 3 months to 53 years (21.0 +/- 16.4, mean +/- SD), and 50 normal subjects (30 men and 20 women) rangin...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2003.12.014
更新日期:2004-05-01 00:00:00
abstract:PURPOSE:We investigated meetings of the Dermatologic and Ophthalmic Drug Advisory Committee (DODAC) and the Ophthalmic Devices Panel (ODP) of the Food and Drug Administration (FDA) to determine whether a relationship exists between receipt of industry payments by speakers of the Open Public Hearing (OPH) portion and th...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.09.043
更新日期:2020-11-06 00:00:00
abstract:PURPOSE:To report the successful use of topical linezolid 0.2% in the treatment of gram-positive bacterial keratitis. STUDY DESIGN:Retrospective, interventional case series. METHODS:All cases of bacterial keratitis treated at the University of Illinois Eye and Ear Infirmary with topical linezolid were identified from...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2013.01.010
更新日期:2013-06-01 00:00:00
abstract::We investigated albumin and IgG concentrations in the aqueous humor of 41 patients before intracapsular cataract extraction (primary samples) and at the end of surgery (secondary samples). Albumin and IgG concentrations were determined in all samples by means of a quantitative fluoroimmunoassay. A short-term topical a...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71914-2
更新日期:1983-12-01 00:00:00
abstract:PURPOSE:To evaluate the long-term safety and efficacy, in a large series of patients, of polyacrylic intraocular lens implants 1 and 3 years after surgery, compared with polymethylmethacrylate intraocular lens implants. METHODS:This was a randomized, prospective study of 1,514 eyes of 1,202 patients that were examined...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-9394(00)00490-6
更新日期:2000-09-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of adjunctive subconjunctival antibiotic injection in the treatment of acute postcataract extraction endophthalmitis. DESIGN:Retrospective cohort study. METHODS:Patients who presented with hand motions or better vision and received subconjunctival antibiotics (SC+ group) were compared...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2003.12.042
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:To document the clinical presentation, treatment, and visual outcome of sarcoid uveitis and to determine the timing and potential risk factors of sarcoidosis progression to symptomatic systemic disease from the time of sarcoid uveitis diagnosis. DESIGN:Retrospective, interventional case series. METHODS:Subj...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.09.013
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:To evaluate the ocular hypotensive effect and safety of carteolol hydrochloride 1% vs timolol maleate 0.5%. METHODS:One hundred seventy-six patients with ocular hypertension or primary open-angle glaucoma were randomly assigned to receive either carteolol 1% twice a day or timolol maleate 0.5% solution twice a...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0002-9394(14)70865-7
更新日期:1997-10-01 00:00:00
abstract::We evaluated carbonic anhydrase inhibitors in a crossover study with a placebo and random allocation of treatment administration. Drugs evaluated included acetazolamide tablets and Sequels, dichlorphenamide, ethoxzolamide, methazolamide, and an ascorbic acid placebo. The best tolerated drug was acetazolamide Sequels. ...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-9394(14)75247-x
更新日期:1978-04-01 00:00:00
abstract:PURPOSE:To identify associations between severity of sickle cell retinopathy (SCR) and other clinical, laboratory, or treatment factors relevant to sickle cell disease (SCD). DESIGN:Retrospective cohort study. METHODS:We investigated clinical, laboratory, and demographic associations with the severity of SCR in 296 p...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.09.025
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To evaluate postoperative corneal deturgescence after Descemet stripping endothelial keratoplasty (DSAEK) using the Visante anterior segment optical coherence tomography (OCT) system (Carl Zeiss Meditec Inc, Dublin, California, USA). DESIGN:Retrospective case series. METHODS:We included 21 eyes (9 males and 1...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.01.016
更新日期:2009-07-01 00:00:00