Abstract：
PURPOSE:To investigate the imaging capabilities of anterior segment optical coherence tomography (AS OCT) in microbial keratitis and to assess whether measurements of the quantitative parameters, infiltrate thickness and corneal thickness, were possible. DESIGN:Prospective, noncomparative, observational case series. METHODS:The study was conducted at a university hospital clinical setting. Seven patients (eyes) with suspected microbial keratitis underwent standard clinical examination and treatment based on slit-lamp clinical findings. AS OCT scanning was performed on presentation and at two follow-up appointments. All scans were carried out with the scanning beam passing through the center of the infiltration and at a specific meridian. Examination was carried out by the same operator. RESULTS:Corneal infiltration was imaged as a hyperreflective area in the corneal stroma on high-resolution AS OCT scans. Retrocorneal pathologic features and anterior chamber inflammatory cells could be imaged. Corneal and infiltrate thickness could be measured with calipers in six cases. In one case, corneal and infiltrate thickness could not be measured because of a thick inflammatory plaque attached to the endothelium. In this case, the width of the plaque was measured on serial scans. CONCLUSIONS:AS OCT imaging provides a range of parameters that can be used to assess microbial keratitis and the treatment response objectively.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Konstantopoulos A,Kuo J,Anderson D,Hossain Pdoi
10.1016/j.ajo.2008.05.030subject
Has Abstractpub_date
2008-10-01 00:00:00pages
534-542issue
4eissn
0002-9394issn
1879-1891pii
S0002-9394(08)00416-9journal_volume
146pub_type
杂志文章abstract：PURPOSE:To highlight the possible role of indocyanine green angiography in predicting future exudative changes in eyes that are candidates for drusen laser treatment. METHODS:In a 56-year-old woman, fluorescein and indocyanine green angiography were performed before drusen laser treatment. RESULTS:The treated eye had...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70875-x
更新日期：1997-10-01 00:00:00
abstract：PURPOSE:To report a case of conjunctival-corneal intraepithelial neoplasia (CCIN) in an elderly African American patient treated with topical mitomycin C and the subsequent complication of limbal stem cell deficiency. DESIGN:Interventional case report. METHODS:A 92-year-old African American woman was diagnosed with C...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2003.10.048
更新日期：2004-05-01 00:00:00
abstract：PURPOSE:To investigate the natural history of Stargardt disease (STGD1) using fixation location and fixation stability. DESIGN:Multicenter, international, prospective cohort study. METHODS:Fixation testing was performed using the Nidek MP-1 microperimeter as part of the prospective, multicenter, natural history study...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2018.06.003
更新日期：2018-09-01 00:00:00
abstract：PURPOSE:To present the carbon dioxide laser as an effective tool for surgical debulking of eyelid and orbital neurofibromas. METHOD:Two patients with neurofibromatosis underwent surgical debulking of their eyelid and orbital plexiform neurofibromas by means of the carbon dioxide laser. RESULTS:Acceptable cosmetic res...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00454-2
更新日期：2000-07-01 00:00:00
abstract：:We performed visual contrast sensitivity testing with Regan's low-contrast letter charts on 30 patients with optic neuropathies and good Snellen visual acuity. Results of this testing were compared with color vision and the presence of an afferent pupillary defect. Regan's low-contrast letter charts were found to be 9...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(88)90176-6
更新日期：1988-02-15 00:00:00
abstract：:We analyzed 34 sets of optic disk photographs from 19 patients with glaucoma who had been followed up for ten years to evaluate changes in the position of the vasculature of the optic disks over time. Each photograph was analyzed by an image analyzer's edge-defining program for optic disk analysis and by three experie...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74101-7
更新日期：1987-11-15 00:00:00
abstract：:Two patients had paresis of the trochlear nerve contralateral to the site of lesions in the brainstem. Both patients had ipsilateral blepharoptosis and miosis suggesting oculosympathetic paresis from involvement of the descending sympathetic tract, adjacent to the fourth cranial nerve nucleus and its fascicles, in the...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(89)90818-0
更新日期：1989-01-15 00:00:00
abstract：:A consecutive group of 67 patients (70 eyes) with senile cataract underwent extracapsular cataract extraction and implantation of a Shearing posterior chamber intraocular lens. After two years of follow-up, there was an 11% +/- 2% decrease in central cell density (P less than .001), a 20% +/- 2% decrease in superior c...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(83)90068-5
更新日期：1983-06-01 00:00:00
abstract：PURPOSE:To report the successful use of topical cysteamine formulated from the oral preparation in the treatment of severe photophobia from corneal crystal deposition in cystinosis. DESIGN:Interventional case report. METHODS:Retrospective chart review. RESULTS:An 8-year-old boy with nephropathic cystinosis was exper...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.05.005
更新日期：2004-10-01 00:00:00
abstract：:I fitted nine aphakic patients who had undergone penetrating keratoplasty with extended-wear hydrophilic contact lenses (55% to 80% water content). All patients had edematous host corneas. Eight of nine developed vascularization of the graft after two to 30 weeks of contact lens wear. One patient developed a presumed ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74912-8
更新日期：1980-09-01 00:00:00
abstract：PURPOSE:To assess the effect of verteporfin photodynamic therapy (PDT) in juxtafoveal choroidal neovascularization (CNV) secondary to pathologic myopia (PM). DESIGN:Prospective, open-label, consecutive, interventional case series. METHODS:We prospectively followed a series of 48 consecutive patients (49 eyes) with pa...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.11.037
更新日期：2007-03-01 00:00:00
abstract：PURPOSE:Transvascular leakage occurs in diabetic retinopathy. The tight junction proteins occludin and zonula occludens-1 (ZO-1) and adherens junction protein cadherin-5 are critical to the maintenance of endothelial barrier. We report a comparison of junction protein expression in the normal and diabetic retina. METH...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00323-2
更新日期：2000-02-01 00:00:00
abstract：PURPOSE:To investigate the validity of assigning patients whose eyes have been removed for ciliary body or choroidal melanoma to risk groups for metastasis based on the identification of microcirculatory patterns in one cross-section taken from the center of the tumor. METHODS:Multiple levels were cut through the bloc...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00092-0
更新日期：1998-09-01 00:00:00
abstract：:We used fluorophotometry and pachymetry to examine the longer-term (more than three months) postoperative effects in the anterior segment of extracapsular lens extraction with and without posterior chamber intraocular lens implantation. Fluorophotometry was performed after oral administration of fluorescein solution (...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76090-8
更新日期：1984-02-01 00:00:00
abstract：PURPOSE:To compare the effect of age, sex and generation on physician practice patterns in Ontario, Canada. DESIGN:Retrospective cohort study. METHODS:Physician and patient data from 1992-2013 were used to calculate the yearly number of physicians, distinct patients seen, patient visits, government payments, physicia...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2019.04.006
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:To report a rare complication, delayed suprachoroidal hemorrhage, of needle revision of a nonfunctioning trabeculectomy bleb in a patient with previously undetected hairy cell leukemia. DESIGN:Interventional case report. METHODS; An 89-year-old man presented with massive delayed suprachoroidal hemorrhage after...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00574-9
更新日期：2003-12-01 00:00:00
abstract：:Pars plana vitrectomy and scleral buckling were performed on 22 eyes of 19 patients for treatment of perforating eye injuries from shotgun pellets. We reviewed the intraoperative findings at the time of vitrectomy to determine what factors might influence final visual acuity. The presence of a total retinal detachment...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)77416-1
更新日期：1992-07-15 00:00:00
abstract：PURPOSE:To evaluate reported ocular side effects associated with isotretinoin usage. METHODS:One thousand seven hundred forty-one case reports received from spontaneous reporting systems, data from the Drug Safety Section of Roche Pharmaceuticals, and the world's literature were evaluated using the World Health Organi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01024-8
更新日期：2001-09-01 00:00:00
abstract：PURPOSE:To assess quantitatively the cumulative effect of hyperglycemia on lens transparency in patients with juvenile type 1 diabetes mellitus. METHODS:Subjects were 30 patients (30 eyes) with type 1 diabetes mellitus who had well-documented records on the duration of diabetes mellitus and condition of glycemic contr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00804-7
更新日期：2001-03-01 00:00:00
abstract：:Nerve fiber counts of 16 normal human optic nerves from subjects aged 3.5 to 82 years showed a significant effect of age (P = .0207). The delay between death or enucleation and fixation also significantly affected the result (P = .0078). The mean (+/- S.E.M.) count for the 16 nerves was 1,244,005 +/- 20,033 fibers, gi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90509-9
更新日期：1984-06-01 00:00:00
abstract：:A new sorting test requires only two minutes for quantitative estimation of saturation thresholds for bluish pigment colors. The test is highly sensitive to and specific for differences between normal subjects and individuals with acquired color vision defects. When combined with Ishihara's pseudo-isochromatic plates,...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(81)90781-9
更新日期：1981-08-01 00:00:00
abstract：:During a two-year period a randomly selected age-stratified sample of subjects 65 years old and older living in Gisborne, New Zealand, was examined by an ophthalmologist to investigate visual acuity and the prevalence of the major disorders of vision in old age. A total of 481 subjects (a response rate of 86.2%) compl...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(82)90073-3
更新日期：1982-08-01 00:00:00
abstract：PURPOSE:To determine photoreceptor oxidative stress and damage in sympathetic ophthalmia (SO). DESIGN:Immunohistologic study. METHODS:Eight formalin-fixed and paraffin-embedded human globes with typical histologic features of SO and five age-matched globes without intraocular inflammation (controls) were retrieved fr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.03.026
更新日期：2008-12-01 00:00:00
abstract：:We studied four patients who, having received postoperative 5-fluorouracil after glaucoma filtering operations, developed serious corneal complications. All four patients had preexisting corneal abnormalities including keratoconjunctivitis sicca, exposure keratopathy, and bullous keratopathy. All of the patients devel...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74224-2
更新日期：1987-02-15 00:00:00
abstract：PURPOSE:To identify factors related to variations in the appearance of untreated AIDS-related cytomegalovirus (CMV) retinitis in severely immunodeficient individuals before the availability of highly active antiretroviral therapy (HAART) and to draw inferences regarding early events in the natural history of CMV retini...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.09.023
更新日期：2008-01-01 00:00:00
abstract：PURPOSE:To report a rare case of craniodiaphysial dysplasia (CDD) that resulted in a profound loss of vision in both eyes. DESIGN:Observational case report. METHODS:A 2-year-old girl presented with midfacial anomaly. Marked thickening and sclerosis in the calvaria and facial bones were detected on the plain x-rays, w...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.08.071
更新日期：2006-02-01 00:00:00
abstract：PURPOSE:To present a case of congenital toxoplasmosis in a newborn whose mother had a 20-year history of a chorioretinal macular scar and positive serology for toxoplasmosis. DESIGN/METHODS:Case report. SETTING/RESULTS: A 38-year-old woman who had been treated for ocular toxoplasmosis 20 years earlier delivered a newb...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00191-0
更新日期：2003-08-01 00:00:00
abstract：PURPOSE:To report the clinical and histopathologic features of orbital hemangiopericytoma. METHOD:We review the clinical and histopathologic features in seven patients. RESULTS:Ultrasonography, computed tomography, and magnetic resonance imaging defined the location and extent of the tumor in each patient but did not...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70904-3
更新日期：1997-11-01 00:00:00
abstract：PURPOSE:To compare race-related differences in estimated rate of change of Bruch's membrane opening-minimum rim width (BMO-MRW) and circumpapillary retinal nerve fiber layer thickness (RNFLT) in healthy, glaucoma suspect, and glaucoma eyes of individuals of European (ED) and African descent (AD). DESIGN:Prospective co...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.08.050
更新日期：2018-12-01 00:00:00
abstract：:We treated nontraumatic ectopia lentis with the irrigation and aspiration method in 30 children and the Keeler/SITE instrument in three. Preoperative visual acuities were 6/21 (20/70) or worse in all patients; postoperatively, visual acuities improved in 29 of the 30 eyes and were 6/18 (20/60) or better in 24 (80%). A...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(81)90354-8
更新日期：1981-01-01 00:00:00
