Contrast sensitivity and color vision in HIV-infected individuals without infectious retinopathy.

Abstract:

PURPOSE:To investigate the relationship between abnormal contrast sensitivity and abnormal color vision among human immunodeficiency virus (HIV)-infected individuals who have normal visual acuity and to seek host factors that predict these abnormalities. DESIGN:Noninterventional, cross-sectional study. METHODS:We evaluated 71 HIV-infected subjects with visual acuity of 20/25 or better, clear media, and no vision-threatening retinal lesions. Visual function was determined using the Pelli-Robson contrast sensitivity test and the Farnsworth-Munsell 100-Hue color test (FM-100). Results were compared with published values for normal populations and to measures of HIV disease severity. We evaluated two levels of impairment for each visual function. "Mild dysfunction" was defined as > or =1 standard deviation (SD), but <2 SD from normal means. "Abnormal" was defined as > or =2 SD from normal means. RESULTS:The prevalences of abnormal contrast sensitivity and abnormal color vision were 7.0% and 9.9%, respectively. We did not identify relationships between impaired contrast sensitivity and impaired color vision. Impaired color vision was associated with increasing age (r = 0.36, P = .002). We could not identify significant correlations between either contrast sensitivity or color vision values and the following factors: current or nadir (lowest previous) CD4+ T-lymphocyte count, HIV blood level, and Karnofsky score. CONCLUSIONS:Abnormal contrast sensitivity and abnormal color vision can occur independently in HIV-infected individuals and can be present in the absence of severe immunosuppression.

journal_name

Am J Ophthalmol

authors

Shah KH,Holland GN,Yu F,Van Natta M,Nusinowitz S,Studies of Ocular Complications of AIDS (SOCA) Research Group.

doi

10.1016/j.ajo.2006.03.046

subject

Has Abstract

pub_date

2006-08-01 00:00:00

pages

284-92

issue

2

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(06)00430-2

journal_volume

142

pub_type

杂志文章
  • Randomized Trial to Evaluate Tandospirone in Geographic Atrophy Secondary to Age-Related Macular Degeneration: The GATE Study.

    abstract:PURPOSE:To determine the safety and efficacy of AL-8309B (tandospirone) in the management of patients with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) and obtain standardized data on GA lesion growth progression. DESIGN:Prospective, controlled, double-masked, randomized, multicenter pha...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ajo.2015.08.024

    authors: Jaffe GJ,Schmitz-Valckenberg S,Boyer D,Heier J,Wolf-Schnurrbusch U,Staurenghi G,Schmidt-Erfurth U,Holz FG

    更新日期:2015-12-01 00:00:00

  • Stereoacuity development in children with normal binocular single vision.

    abstract::We made 344 stereoacuity determinations (Titmus Stereotest) on 321 children, ages 1 1/2 to 13 years, who had normal binocular single vision tested by other factors. The data showed a gradual improvement in stereoacuity scores with increasing age--up to age 9--when a normal stereoacuity of 40 seconds of arc was consist...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(75)90679-0

    authors: Romano PE,Romano JA,Puklin JE

    更新日期:1975-06-01 00:00:00

  • Diffuse unilateral subacute neuroretinitis with unusual findings.

    abstract:PURPOSE:To report two cases of diffuse unilateral subacute neuroretinitis (DUSN) with unusual findings. DESIGN:Observational and interventional case series. METHODS:Two patients with DUSN were found to have the unusual findings of a large live worm in one eye and macular cyst in the other. Both patients underwent fun...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2006.06.005

    authors: Vedantham V,Vats MM,Kakade SJ,Ramasamy K

    更新日期:2006-11-01 00:00:00

  • Echographic localization of corticosteroids after periocular injection.

    abstract::The location of repository corticosteroid after subtenon injection was determined in 24 patients with macular edema associated with uveitis or anterior segment surgery. Standardized A-scan and B-scan echography were performed immediately before and after each injection. Localization was compared after subtenon injecti...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Freeman WR,Green RL,Smith RE

    更新日期:1987-03-15 00:00:00

  • Twice-yearly exams unnecessary for patients taking quetiapine.

    abstract:PURPOSE:To determine the necessity for the heightened level of monitoring for cataract development in patients taking quetiapine (Seroquel, AstraZeneca Pharmaceuticals, Wilmington, Delaware) dictated by the Physicians' Desk Reference. Also, to explore the possibility of cataractogenesis because of quetiapine therapy. ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2004.05.038

    authors: Fraunfelder FW

    更新日期:2004-11-01 00:00:00

  • Surgical management of retinal traction caused by toxocariasis.

    abstract::We reviewed the results of vitreous surgery in 12 eyes of 12 patients with tractional macular detachment from Toxocara canis. We performed a vitrectomy and membrane peeling in all eyes, with additional scleral buckling in four eyes. After a minimum of six months' follow-up, ten of the 12 eyes (83%) had complete retina...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)73253-2

    authors: Small KW,McCuen BW 2nd,de Juan E Jr,Machemer R

    更新日期:1989-07-15 00:00:00

  • Comparison of a 3- and 6-mm incision in combined phacoemulsification and trabeculectomy.

    abstract::We studied 216 eyes of 160 patients who underwent combined phacoemulsification and posterior chamber intraocular lens implantation with trabeculectomy. The mean follow-up was 18.7 months, with a minimum follow-up of six months. To assess the safety and efficacy of a recently developed 3-mm incision procedure with fold...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)72258-5

    authors: Lyle WA,Jin JC

    更新日期:1991-02-15 00:00:00

  • Iris suture fixation of subluxated intraocular lenses.

    abstract:PURPOSE:To assess the results of iris suture fixation of subluxated intraocular lenses. DESIGN:Retrospective study. METHODS:This was a nonrandomized chart review of eyes with subluxated intraocular lenses that underwent iris suture fixation at an academic institutional care center. Seventy-two eyes of 67 consecutive ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2014.11.009

    authors: Soiberman U,Pan Q,Daoud Y,Murakami P,Stark WJ

    更新日期:2015-02-01 00:00:00

  • A simple transposition procedure for complicated strabismus.

    abstract::We combined a recession or resection of recti muscles with a vertical or horizontal transposition to correct a complicated paralytic ocular deviation in eight patients. The transposed muscles were reattached to the globe parallel to the spiral of Tillaux and adjacent to the paralyzed muscle. Postoperatively, seven pat...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)72313-x

    authors: Buckley EG,Townshend LM

    更新日期:1991-03-15 00:00:00

  • Brief hospital admissions for pediatric strabismus surgery.

    abstract::We performed strabismus surgery on 170 children on an outpatient basis. Endotracheal intubation was utilized in all cases as the means of delivery of the anesthetic agent. Atropine used alone as a preoperative medication reduced the incidence of postoperative vomiting. Parental acceptance of this method of surgery was...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(75)90221-4

    authors: Weinstock SM,Flynn JT

    更新日期:1975-09-01 00:00:00

  • Evaluation of Tear Protein Markers in Dry Eye Disease with Different Lymphotoxin-Alpha Expression Levels.

    abstract:PURPOSE:To compare tear protein markers between normal subjects and patients with dry eye (DE) and high and low lymphotoxin-alpha (LT-α) levels. DESIGN:Prospective cross-sectional study. METHODS:Patients with DE were divided into low (≤700 pg/mL) and high (>700 pg/mL) LT-α groups. Twelve protein markers were measured...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2020.03.013

    authors: Chen H,Chen H,Liang L,Zhong Y,Liang Y,Yu Y,Huang S,Lu X

    更新日期:2020-09-01 00:00:00

  • Enhanced circulating soluble LR11 in patients with diabetic retinopathy.

    abstract:PURPOSE:To investigate the relationship of circulating levels of soluble form of LR11 (sLR11; also called SorLA or SORL1), with the progression of proliferative diabetic retinopathy (PDR) in patients with type 2 diabetes mellitus. DESIGN:Cross-sectional study. METHODS:Fifty-four patients with type 2 diabetes mellitus...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2012.01.035

    authors: Takahashi M,Bujo H,Shiba T,Jiang M,Maeno T,Shirai K

    更新日期:2012-07-01 00:00:00

  • Optical coherence tomography of idiopathic polypoidal choroidal vasculopathy.

    abstract:PURPOSE:To document and study the cross-sectional structures of polypoidal elements using optical coherence tomography in eyes with idiopathic polypoidal choroidal vasculopathy. METHODS:Optical coherence tomography images of two eyes with idiopathic polypoidal choroidal vasculopathy were correlated with slit-lamp biom...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(98)00411-5

    authors: Iijima H,Imai M,Gohdo T,Tsukahara S

    更新日期:1999-03-01 00:00:00

  • Clinical benefits of the Boston Ocular Surface Prosthesis.

    abstract:PURPOSE:To evaluate the effects of the Boston Ocular Surface Prosthesis (Boston Foundation for Sight, Needham, Massachusetts, USA) on visual acuity (VA) and visual functioning in patients with severe corneal ectasia, irregular astigmatism, or ocular surface disease. DESIGN:Prospective, interventional case series. MET...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2009.07.037

    authors: Stason WB,Razavi M,Jacobs DS,Shepard DS,Suaya JA,Johns L,Rosenthal P

    更新日期:2010-01-01 00:00:00

  • Ahmed valve implantation with adjunctive mitomycin C and 5-fluorouracil: long-term outcomes.

    abstract:PURPOSE:To evaluate long-term outcomes after Ahmed valve implantation in patients with glaucoma when using adjunctive intraoperative mitomycin C (MMC) and postoperative 5-fluorouracil (5-FU). DESIGN:Retrospective, interventional, consecutive case series. METHODS:A consecutive series of eyes undergoing Ahmed valve imp...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2008.04.008

    authors: Alvarado JA,Hollander DA,Juster RP,Lee LC

    更新日期:2008-08-01 00:00:00

  • Correlation between quantitative measurements of tear film lipid layer thickness and meibomian gland loss in patients with obstructive meibomian gland dysfunction and normal controls.

    abstract:PURPOSE:To evaluate the correlation between tear film lipid layer thickness and other objective measurements such as tear film break-up time (TBUT), upper and lower meibomian gland losses, and Schirmer 1 test in patients with obstructive meibomian gland dysfunction (MGD) and normal controls. DESIGN:Cross-sectional stu...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2013.01.008

    authors: Eom Y,Lee JS,Kang SY,Kim HM,Song JS

    更新日期:2013-06-01 00:00:00

  • Evidence of genetic heterogeneity in autosomal recessive congenital fibrosis of the extraocular muscles.

    abstract:PURPOSE:Autosomal recessive congenital fibrosis of the extraocular muscles (CFEOM2) has been described in families from Saudi Arabia. Affected individuals have ptosis and exotropic ophthalmoplegia, and their disease has been mapped to chromosome 11q13. Here, we describe the phenotypic findings in a similarly affected Y...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(99)00467-5

    authors: Traboulsi EI,Lee BA,Mousawi A,Khamis AR,Engle EC

    更新日期:2000-05-01 00:00:00

  • Serum levels of triamcinolone acetonide after intravitreal injection.

    abstract:PURPOSE:To evaluate serum levels of triamcinolone acetonide after intravitreal high-dose injection. DESIGN:Prospective, interventional case series study. METHODS:For 20 consecutive patients, venous blood samples were taken before and 13 +/- 19 days (range 4 to 92) after an intravitreal injection of 20 to 25 mg triamc...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2004.01.008

    authors: Degenring RF,Jonas JB

    更新日期:2004-06-01 00:00:00

  • Vitreous surgery for hemorrhagic and fibrous complications of age-related macular degeneration.

    abstract::We applied vitreous surgical techniques in the treatment of hemorrhagic and fibrous complications of choroidal neovascular membranes by removing subretinal scars or hemorrhage, or both, in four patients. The surgical goals were achieved in all patients. Visual acuity improved in three patients. The major complication ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(88)90116-x

    authors: de Juan E Jr,Machemer R

    更新日期:1988-01-15 00:00:00

  • One-year results of reduced-fluence photodynamic therapy for polypoidal choroidal vasculopathy.

    abstract:PURPOSE:To report 1-year results of reduced-fluence photodynamic therapy (PDT) for polypoidal choroidal vasculopathy (PCV) in Japanese patients. DESIGN:Prospective interventional case series. METHODS:In the present study, 28 treatment-naïve eyes of 28 consecutive patients underwent PDT with a reduced laser fluence of...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ajo.2009.09.020

    authors: Yamashita A,Shiraga F,Shiragami C,Ono A,Tenkumo K

    更新日期:2010-03-01 00:00:00

  • Efficacy and safety of nedocromil sodium ophthalmic solution in the treatment of seasonal allergic conjunctivitis.

    abstract::To assess the efficacy and safety of twice-daily administration of nedocromil sodium 2% ophthalmic solution, we performed a multicenter study involving 140 patients with seasonal allergic conjunctivitis. Subjects had a history of seasonal allergic conjunctivitis and positive results of a skin test to ragweed. The tria...

    journal_title:American journal of ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0002-9394(14)75754-x

    authors: Blumenthal M,Casale T,Dockhorn R,Jarmoszuk I,Kaiser H,Smith R,Zeitz HJ

    更新日期:1992-01-15 00:00:00

  • Outcome of cataract operations performed to permit diagnosis, to determine eligibility for laser therapy, or to perform laser therapy of retinal disorders.

    abstract::Cataract operations may be recommended when retinal disease is suspected but cannot be adequately diagnosed or treated because of lens opacity. We evaluated the outcome of cataract operations performed under those circumstances. We reviewed the records of 119 patients who were examined at the Wilmer Retinal Vascular C...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)75793-9

    authors: Edwards MG,Schachat AP,Bressler SB,Bressler NM

    更新日期:1994-10-15 00:00:00

  • Chloral hydrate sedation as a substitute for examination under anesthesia in pediatric ophthalmology.

    abstract::We examined more than 300 children as outpatients with orally administered chloral hydrate sedation during the past three years; 175 of them have been examined in the last year. Without chloral hydrate sedation, examination under anesthesia would have been necessary or the results would have been less than satisfactor...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(80)90066-5

    authors: Judisch GF,Anderson S,Bell WE

    更新日期:1980-04-01 00:00:00

  • Cystoid macular edema associated with ocular hypotensive lipids.

    abstract:PURPOSE:To report angiographically documented cystoid macula edema associated with the use of each of the three newly available ocular hypotensive lipids: unoprostone, travaprost, and bimatoprost. DESIGN:Observational case series. METHODS:Retrospective review of three patients in a clinical practice who had uncontrol...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(01)01411-8

    authors: Wand M,Gaudio AR

    更新日期:2002-03-01 00:00:00

  • A dose-response study of piloplex for duration of action.

    abstract::The duration of reduction in intraocular pressure after single-dose administration of three concentrations of piloplex and the vehicle of the drug was evaluated in 12 patients with open-angle glaucoma in a randomized, double-masked, crossover study. Piloplex lowered intraocular pressure in a dose-related fashion, with...

    journal_title:American journal of ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-9394(14)75861-1

    authors: Klein HZ,Lugo M,Shields MB,Leon J,Duzman E

    更新日期:1985-01-15 00:00:00

  • A proposed mild type of acute retinal necrosis syndrome.

    abstract::Six patients had peripheral to midperipheral pale yellow retinal exudates typical of acute retinal necrosis syndrome but which extended gradually to the posterior pole and remained isolated without becoming confluent. These exudates resulted in localized retinochoroidal degeneration without retinal detachment, in cont...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/0002-9394(88)90047-5

    authors: Matsuo T,Nakayama T,Koyama T,Koyama M,Matsuo N

    更新日期:1988-06-15 00:00:00

  • Dislocation of the donor graft to the posterior segment in descemet stripping automated endothelial keratoplasty.

    abstract:PURPOSE:To report a series of dislocations of the donor graft into the posterior segment associated with Descemet stripping endothelial keratoplasty (DSAEK) and to identify possible risk factors for dislocation and clinical outcomes. DESIGN:Retrospective case series. METHODS:Cases of donor graft dislocation into the ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ajo.2011.09.006

    authors: Afshari NA,Gorovoy MS,Yoo SH,Kim T,Carlson AN,Rosenwasser GO,Griffin NB,McCuen BW 2nd,Toth CA,Price FW Jr,Price M,Fernandez MM

    更新日期:2012-04-01 00:00:00

  • Sclerochoroidal calcification associated with Gitelman syndrome.

    abstract:PURPOSE:To investigate sclerochoroidal calcification in a patient with Gitelman syndrome. METHOD:Case report. Bilateral fundus abnormalities observed in a 58-year-old woman were documented with fluorescein angiography and tomodensitometry. RESULTS:Symmetric yellow-white subretinal lesions were observed in the superot...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(99)00277-9

    authors: Bourcier T,Blain P,Massin P,Grünfeld JP,Gaudric A

    更新日期:1999-12-01 00:00:00

  • Expression of extradomain-B-containing fibronectin in subretinal choroidal neovascular membranes.

    abstract:PURPOSE:To investigate the presence of the fibronectin isoform containing the extradomain B (B-FN), a marker-protein of angiogenesis, in surgically excised human choroidal neovascular membranes (CNVM) to evaluate whether B-FN could be used as a therapeutic target for specific antibody-photosensitizer immunoconjugates. ...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(02)01839-1

    authors: Nicolò M,Birò A,Cardillo-Piccolino F,Castellani P,Giovannini A,Mariotti C,Zingirian M,Neri D,Zardi L

    更新日期:2003-01-01 00:00:00

  • Metastatic Peptostreptococcus intermedius endophthalmitis after a dental procedure.

    abstract::A 46-year-old man developed symptoms of a chronic progressive uveitis in his right eye approximately one week after a dental procedure. The patient's intraocular inflammation was not diminished by massive treatment with topical and systemic corticosteroid therapy or intravenously administered adrenocorticotropic hormo...

    journal_title:American journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0002-9394(14)77101-6

    authors: May DR,Peyman GA,Raichand M,Friedman E

    更新日期:1978-05-01 00:00:00