当前位置： SCI文献检索 > AMERICAN JOURNAL OF OPHTHALMOLOGY期刊下所有文献 > Optical coherence tomography measurement of nerve fiber layer thickness and the likelihood of a visual field defect.

Optical coherence tomography measurement of nerve fiber layer thickness and the likelihood of a visual field defect.

Abstract：

PURPOSE:To determine if optical coherence tomography (OCT) measurements of nerve fiber layer (NFL) thickness can be used to predict the presence of visual field defects (VFD) associated with glaucoma. DESIGN:Quota-sampled, cross-sectional study. METHODS:Retrospective study of OCT NFL thickness measurements in 276 eyes of 276 subjects. All persons received OCT NFL thickness analysis; 136 eyes underwent frequency-doubling technology (FDT) perimetry; and 140 eyes underwent Swedish interactive threshold algorithm (SITA) perimetry. We defined a parameter called NFL(50), which is the NFL thickness value at which there was a 50% likelihood of a VFD with either SITA or FDT perimetry. We evaluated the use of NFL(50). RESULTS:The mean NFL thickness with (n = 68) and without (n = 68) a VFD in the FDT group was 93.2 microm +/- 22.6 and 108.4 microm +/- 14.1, respectively. The mean NFL thickness with (n = 70) and without (n = 70) a VFD in the SITA group was 78.9 microm +/- 24.8 and 103.0 microm +/- 18.0, respectively. The FDT mean NFL(50) value was 98.5 microm. The SITA mean NFL(50) value was 87.0 microm. The area under the receiver operator characteristic (AROC) curve for mean NFL was 0.73, and the positive predictive value (PPV) for FDT mean NFL(50) was 72.2%. For SITA mean NFL, the AROC was 0.79 and the PPV for NFL(50) was 77.2%. CONCLUSION:Nerve fiber layer thickness analysis using OCT may be clinically useful in identifying subjects who have visual field loss. However, the PPV suggests that OCT may need higher resolution and better reproducibility to enhance its sensitivity and specificity for population screening.

journal_name

Am J Ophthalmol

journal_title

American journal of ophthalmology

authors

Williams ZY,Schuman JS,Gamell L,Nemi A,Hertzmark E,Fujimoto JG,Mattox C,Simpson J,Wollstein G

doi

10.1016/s0002-9394(02)01683-5

subject

Has Abstract

pub_date

2002-10-01 00:00:00

pages

538-46

issue

4

eissn

0002-9394

issn

1879-1891

pii

S0002939402016835

journal_volume

134

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF OPHTHALMOLOGY文献大全
  • Retinal nerve fiber layer atrophy is associated with visual field loss over time in glaucoma suspect and glaucomatous eyes.

    abstract：PURPOSE:To compare prospectively detection of progressive retinal nerve fiber layer thickness (RNFL) atrophy identified using time-domain optical coherence tomography with visual field progression using standard automated perimetry in glaucoma suspect and preperimetric glaucoma patients or perimetric glaucoma patients....

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ajo.2012.07.005

    authors： Sehi M,Zhang X,Greenfield DS,Chung Y,Wollstein G,Francis BA,Schuman JS,Varma R,Huang D,Advanced Imaging for Glaucoma Study Group.

    更新日期：2013-01-01 00:00:00

  • An ultrastructural and histochemical study of long-term wound healing after radial keratotomy.

    abstract：:Using correlative microscopy and plant lectins conjugated to fluorescent dyes, we studied two human corneal specimens obtained 66 and 70 months after radial keratotomy. In one case a second radial keratotomy had been performed 11 months before we obtained the corneal specimen, which allowed us to compare wounds 11 and...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(14)77767-0

    authors： Binder PS,Nayak SK,Deg JK,Zavala EY,Sugar J

    更新日期：1987-03-15 00:00:00

  • Refractive changes after pediatric intraocular lens implantation.

    abstract：PURPOSE:To report refractive changes after cataract surgery and intraocular lens implantation in infants and children. METHODS:In an ongoing prospective study, the refractive errors of all patients younger than 18 years undergoing intraocular lens implantation were determined at 6 weeks, 3 months, 6 months, and 1 year...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(98)00247-5

    authors： Enyedi LB,Peterseim MW,Freedman SF,Buckley EG

    更新日期：1998-12-01 00:00:00

  • Graft edema after suture removal.

    abstract：:Graft edema developed after removal of continuous monofilament sutures in six eyes of six patients in whom no wound dehiscence occurred. All sutures were removed at least one year after penetrating keratoplasty, and graft edema was noted one day after suture removal. In all cases, partial or total resolution of graft ...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/0002-9394(79)90461-6

    authors： Goldberg DB,Schanzlin DJ,Mondino BJ,Brown SI

    更新日期：1979-08-01 00:00:00

  • Changes in contrast sensitivity after surgery for macula-on rhegmatogenous retinal detachment.

    abstract：PURPOSE:To evaluate changes in contrast sensitivity after surgery for macula-on rhegmatogenous retinal detachment (RRD). DESIGN:Prospective, interventional, consecutive, case-control study. METHODS:This study included 84 eyes of 84 patients with unilateral macula-on RRD undergoing primary scleral buckling or vitrecto...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ajo.2013.05.017

    authors： Okamoto F,Sugiura Y,Okamoto Y,Hiraoka T,Oshika T

    更新日期：2013-10-01 00:00:00

  • Vitrectomy for perforating eye injuries from shotgun pellets.

    abstract：:Pars plana vitrectomy and scleral buckling were performed on 22 eyes of 19 patients for treatment of perforating eye injuries from shotgun pellets. We reviewed the intraoperative findings at the time of vitrectomy to determine what factors might influence final visual acuity. The presence of a total retinal detachment...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(14)77416-1

    authors： Alfaro DV,Tran VT,Runyan T,Chong LP,Ryan SJ,Liggett PE

    更新日期：1992-07-15 00:00:00

  • Infectious scleritis after retinal surgery.

    abstract：PURPOSE:To report a series of patients in whom infectious scleritis developed after vitreoretinal surgery. DESIGN:Interventional case series of four patients. METHODS:Medical records of patients at a single institution in whom infectious scleritis developed after vitreoretinal surgery were reviewed. RESULTS:In three...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ajo.2007.11.024

    authors： Rich RM,Smiddy WE,Davis JL

    更新日期：2008-04-01 00:00:00

  • Comparison of results of excimer laser correction of all degrees of myopia at 12 months postoperatively. The Melbourne Excimer Laser Group.

    abstract：UNLABELLED:To examine prospectively the efficacy and safety of photorefractive keratectomy and photoastigmatic refractive keratectomy. METHODS:We treated 645 eyes (440 patients) with a VisX Twenty/Twenty excimer laser and followed them up for 12 months. RESULTS:The percentage of eyes with myopia between -5.01 and -10...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(14)70433-7

    authors： McCarty CA,Aldred GF,Taylor HR

    更新日期：1996-04-01 00:00:00

  • Modified technique of haptic externalization for scleral fixation of dislocated posterior chamber lens implants.

    abstract：PURPOSE:To describe a modified technique of haptic externalization during repositioning of dislocated posterior chamber lens implants, which facilitates placement of scleral fixation sutures around the haptic for implant stabilization. METHODS:We describe a technique of repositioning a dislocated posterior chamber imp...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(00)00650-4

    authors： Kokame GT,Atebara NH,Bennett MD

    更新日期：2001-01-01 00:00:00

  • A hyperdry amniotic membrane patch using a tissue adhesive for corneal perforations and bleb leaks.

    abstract：PURPOSE:To evaluate the efficacy of hyperdry amniotic membrane (AM) patching attached using a tissue adhesive for corneal perforations and glaucoma filtering bleb leaks. DESIGN:Prospective, noncomparative, interventional case series. METHODS:Five eyes of 5 patients (glaucoma bleb leaks, 2 eyes; corneal perforations, ...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ajo.2009.03.030

    authors： Kitagawa K,Yanagisawa S,Watanabe K,Yunoki T,Hayashi A,Okabe M,Nikaido T

    更新日期：2009-09-01 00:00:00

  • Reduction of retinal sensitivity in eyes with reticular pseudodrusen.

    abstract：PURPOSE:To evaluate the effect of macular reticular pseudodrusen on retinal function using multiple imaging methods. DESIGN:Prospective cross-sectional study. METHODS:Thirteen eyes with reticular pseudodrusen, but without any other macular abnormality or glaucoma, and 20 normal eyes were evaluated. All subjects under...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ajo.2013.06.036

    authors： Ooto S,Ellabban AA,Ueda-Arakawa N,Oishi A,Tamura H,Yamashiro K,Tsujikawa A,Yoshimura N

    更新日期：2013-12-01 00:00:00

  • Beta-ray treatment of malignant epithelial tumors of the conjunctiva.

    abstract：:Fifteen patients with malignant epithelial tumors of the conjunctiva were treated with beta-ray ocular applicators filled with radioactive strontium and yttrium (90Sr/90Y). Histologic examination confirmed the diagnosis. There were ten squamous cell carcinomas, four carcinomas in situ, and one case of epidermidalizati...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章,评审

    doi：10.1016/0002-9394(76)90731-5

    authors： Lommatzsch P

    更新日期：1976-02-01 00:00:00

  • Vaccinia keratouveitis manifesting as a masquerade syndrome.

    abstract：:A patient who used contact lenses and had a history of blunt trauma developed vaccinia keratouveitis after accidental ocular autoinoculation from a recent vaccination site. Corneal and conjunctival cultures were taken for bacteria, fungi, Acanthamoeba, and viruses. Viral-like cytopathic effects became evident in tissu...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(14)70008-x

    authors： Lee SF,Buller R,Chansue E,Hanika WC,Brunt EM,Aquino T,Storch GA,Pepose JS

    更新日期：1994-04-15 00:00:00

  • Positional changes in the vasculature of the optic disk in glaucoma.

    abstract：:We analyzed 34 sets of optic disk photographs from 19 patients with glaucoma who had been followed up for ten years to evaluate changes in the position of the vasculature of the optic disks over time. Each photograph was analyzed by an image analyzer's edge-defining program for optic disk analysis and by three experie...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(14)74101-7

    authors： Varma R,Spaeth GL,Hanau C,Steinmann WC,Feldman RM

    更新日期：1987-11-15 00:00:00

  • One-year outcomes of panretinal photocoagulation in proliferative diabetic retinopathy.

    abstract：PURPOSE:To describe the clinical features and complications of diabetic retinopathy, visual acuity, and number of repeat treatments after panretinal photocoagulation for proliferative diabetic retinopathy in a tertiary care center. METHODS:A cohort study was conducted with data collection from medical records of patie...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(99)00322-0

    authors： Kaiser RS,Maguire MG,Grunwald JE,Lieb D,Jani B,Brucker AJ,Maguire AM,Ho AC,Fine SL

    更新日期：2000-02-01 00:00:00

  • Direct Versus Indirect Corneal Neurotization for the Treatment of Neurotrophic Keratopathy: A Multicenter Prospective Comparative Study.

    abstract：PURPOSE:To analyze the comparative safety and efficacy of two techniques of corneal neurotization (CN) (direct corneal neurotization [DCN] vs indirect corneal neurotization [ICN]) for the treatment of neurotrophic keratopathy (NK). DESIGN:Multicenter interventional prospective comparative case series. METHODS:This st...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ajo.2020.07.003

    authors： Fogagnolo P,Giannaccare G,Bolognesi F,Digiuni M,Tranchina L,Rossetti L,Dipinto A,Allevi F,Lozza A,Rabbiosi D,Mariani S,Pellegrini M,Cazzola FE,Bagaglia S,Mazzotta C,Gabriele G,Gennaro P,Badiali G,Marchetti C,Campos

    更新日期：2020-12-01 00:00:00

  • Conductive keratoplasty: histological study of human corneas.

    abstract：PURPOSE:To determine the morphologic changes in human corneas over time following radiofrequency-based conductive keratoplasty (CK) treatment. DESIGN:Prospective, observational case series. METHODS:In a single-center study six human corneas of six patients with localized peripheral keratoconus underwent CK treatment ...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ajo.2005.06.027

    authors： Naoumidi TL,Pallikaris IG,Naoumidi II,Astyrakakis NI

    更新日期：2005-12-01 00:00:00

  • Transient, profound cataract associated with intracameral 5-fluorouracil.

    abstract：PURPOSE:To report a transient cataract after bleb needling and subconjunctival injection of 5-fluorouracil. DESIGN:Observational case report. METHODS:A 51-year-old man had an encapsulated bleb after filtering surgery. The bleb was needled, and 5 mg of 5-fluorouracil was injected adjacent to the bleb. RESULTS:Within ...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(02)01828-7

    authors： Libre PE

    更新日期：2003-01-01 00:00:00

  • Hepatocyte growth factor levels in the vitreous of patients with proliferative vitreoretinopathy.

    abstract：PURPOSE:To determine whether the hepatocyte growth factor is increased in the vitreous of patients with proliferative vitreoretinopathy. METHODS:We assayed hepatocyte growth factor levels by enzyme-linked immunosorbent assay (ELISA) in vitreous samples from 65 consecutive eyes (65 patients) with proliferative vitreore...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(00)00360-3

    authors： Mitamura Y,Takeuchi S,Matsuda A,Tagawa Y,Mizue Y,Nishihira J

    更新日期：2000-05-01 00:00:00

  • The predictive value of serum angiotensin converting enzyme and lysozyme levels in the diagnosis of ocular sarcoidosis.

    abstract：:We determined the serum angiotensin converting enzyme and lysozyme levels in 221 patients with uveitis and in 67 control subjects. Angiotensin converting enzyme and lysozyme levels were found to be age dependent. Of the 221 patients, 12 had sarcoidosis. In patients with uveitis who had an angiotensin converting enzyme...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/0002-9394(87)90406-5

    authors： Baarsma GS,La Hey E,Glasius E,de Vries J,Kijlstra A

    更新日期：1987-09-15 00:00:00

  • Choroidal Thickness Profiles in Myopic Eyes of Young Adults in the Correction of Myopia Evaluation Trial Cohort.

    abstract：PURPOSE:To examine the relationship of choroidal thickness with axial length (AL) and myopia in young adult eyes in the ethnically diverse Correction of Myopia Evaluation Trial (COMET) cohort. DESIGN:Cross-sectional, multicenter study. METHODS:In addition to measures of myopia by cycloplegic autorefraction and AL by ...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ajo.2015.04.018

    authors： Harb E,Hyman L,Gwiazda J,Marsh-Tootle W,Zhang Q,Hou W,Norton TT,Weise K,Dirkes K,Zangwill LM,COMET Study Group.

    更新日期：2015-07-01 00:00:00

  • Identifying early glaucoma with optical coherence tomography.

    abstract：PURPOSE:To evaluate performance of optical coherence tomography (OCT) for detection of early glaucoma. DESIGN:Observational case-control study. METHODS: SETTING:University-based tertiary care center. STUDY POPULATION:One eye from 50 normals, 42 glaucoma suspects, and 59 early glaucoma patients meeting the following...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ajo.2003.09.004

    authors： Nouri-Mahdavi K,Hoffman D,Tannenbaum DP,Law SK,Caprioli J

    更新日期：2004-02-01 00:00:00

  • A simple transposition procedure for complicated strabismus.

    abstract：:We combined a recession or resection of recti muscles with a vertical or horizontal transposition to correct a complicated paralytic ocular deviation in eight patients. The transposed muscles were reattached to the globe parallel to the spiral of Tillaux and adjacent to the paralyzed muscle. Postoperatively, seven pat...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(14)72313-x

    authors： Buckley EG,Townshend LM

    更新日期：1991-03-15 00:00:00

  • Isolated Orbital Aspergillosis in Immunocompetent Patients: A Multicenter Study.

    abstract：OBJECTIVE:To report clinicopathologic features, radiologic findings, and treatment outcomes of isolated, orbital aspergillosis. DESIGN:Multicenter, retrospective case series. METHODS:setting: Multicenter. PARTICIPANTS:There were 8 lesions in 8 eyes of 8 patients with isolated, orbital aspergillosis. PROCEDURE:Revie...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ajo.2016.03.007

    authors： Aggarwal E,Mulay K,Menon V,Sundar G,Honavar SG,Sharma M

    更新日期：2016-05-01 00:00:00

  • Orbital invasion by an intracranial chordoma.

    abstract：:A 26-year-old woman experienced bilateral hearing loss, progressive nasal obstruction, and rhinorrhea. Examination disclosed a retropharyngeal mass. A needle biopsy specimen of the mass showed that it was a chordoma. The patient underwent surgery to remove the mass and received a postoperative course of radioactive co...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(14)75899-4

    authors： Ferry AP,Haddad HM,Goldman JL

    更新日期：1981-07-01 00:00:00

  • Verteporfin photodynamic therapy for the treatment of persistent subfoveal choroidal neovascularization after external beam radiotherapy: one-year results.

    abstract：PURPOSE:To determine the safety and efficacy of verteporfin photodynamic therapy (PDT) for the treatment of persistent choroidal neovascularization (CNV) previously treated with external beam radiotherapy (EBRT). DESIGN:Retrospective case series. METHODS:Verteporfin PDT was performed on 14 eyes of 13 patients with sy...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ajo.2004.09.019

    authors： Gupta R,Browning AC,Wu K,Sokal M,Amoaku WM

    更新日期：2005-03-01 00:00:00

  • Optic disk edema associated with sudden-onset anterior uveitis.

    abstract：PURPOSE:To describe the clinical characteristics and course of optic disk edema (ODE) associated with isolated sudden-onset anterior uveitis. DESIGN:Interventional, noncomparative retrospective case series. METHODS:Review of patients with sudden-onset anterior uveitis and concomitant ODE seen in an academic uveitis r...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ajo.2005.03.062

    authors： Monheit BE,Read RW

    更新日期：2005-10-01 00:00:00

  • Late results of superior oblique muscle tenotomy in true Brown's syndrome.

    abstract：:We re-assessed nine patients (aged 2 to 28 years) in whom true Brown's syndrome had been diagnosed and superior oblique muscle tenotomy performed. The postoperative period ranged from three to 12 years. The final results were divided into three groups: (1) Patients with partial residual Brown's syndrome postoperativel...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/0002-9394(80)90173-7

    authors： Crawford JS,Orton RB,Labow-Daily L

    更新日期：1980-06-01 00:00:00

  • Porphyria cutanea tarda presenting as cicatricial conjunctivitis.

    abstract：PURPOSE:To report a case of porphyria cutanea tarda presenting as cicatricial conjunctivitis. DESIGN:Observational study. METHODS:A 31-year-old man presented with bilateral inferior symblepharon, superior tarsal conjunctival scarring and concretions, and recurrent conjunctival and episcleral injection. RESULTS:Four ...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(02)01623-9

    authors： Park AJ,Webster GF,Penne RB,Raber IM

    更新日期：2002-10-01 00:00:00

  • Retinal detachment after phacoemulsification: a study of 114 cases.

    abstract：PURPOSE:To analyze the features of retinal detachment (RD) occurring after cataract surgery performed by Kelman phacoemulsification (KPE) and to identify any potential correlations between KPE intraoperative complications and the features of RD (incidence apart) as well as the final visual outcome. DESIGN:Intervention...

    journal_title：American journal of ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0002-9394(02)01347-8

    authors： Haddad WM,Monin C,Morel C,Larricart P,Quesnot S,Ameline B,Loison K,Belghiti A,Laroche L

    更新日期：2002-05-01 00:00:00