Abstract：
PURPOSE:To determine whether the hepatocyte growth factor is increased in the vitreous of patients with proliferative vitreoretinopathy. METHODS:We assayed hepatocyte growth factor levels by enzyme-linked immunosorbent assay (ELISA) in vitreous samples from 65 consecutive eyes (65 patients) with proliferative vitreoretinopathy (23 eyes), rhegmatogenous retinal detachment (22 eyes), and macular hole or idiopathic epiretinal membrane (control subjects, 20 eyes) having undergone pars plana vitrectomy. RESULTS:Vitreous levels of hepatocyte growth factor were 3.94 +/- 2.29 (mean +/- SD) ng/ml in proliferative vitreoretinopathy, 2.02 +/- 0.84 ng/ml in rhegmatogenous retinal detachment, and 2.16 +/- 1.39 ng/ml in the control subjects. The vitreous levels in proliferative vitreoretinopathy were much greater than levels in rhegmatogenous retinal detachment (P =.0002) and in the control subjects (P =.0007). In proliferative vitreoretinopathy, there was a tendency toward higher levels in eyes with grade D by the Retina Society terminology. CONCLUSION:The results suggest the possibility that hepatocyte growth factor may play a role in the pathogenesis of proliferative vitreoretinopathy.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Mitamura Y,Takeuchi S,Matsuda A,Tagawa Y,Mizue Y,Nishihira Jdoi
10.1016/s0002-9394(00)00360-3subject
Has Abstractpub_date
2000-05-01 00:00:00pages
678-80issue
5eissn
0002-9394issn
1879-1891pii
S0002939400003603journal_volume
129pub_type
杂志文章abstract：:To facilitate placing pars plana infusion ports, we modified the shaft of a piece of 10-gauge tubing or of a hypodermic needle by removing the beveled tip and Luer hub, passing the tubing through the inserter sleeve, and then reattaching the tubing to the Luer hub. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(78)90251-9
更新日期：1978-09-01 00:00:00
abstract：:We analyzed the vitreous findings in 62 patients (62 eyes) with major branch retinal vein occlusion to determine whether vitreous examination was useful in predicting the development of retinal or disk neovascularization, or both. In 18 eyes with no or partial posterior vitreous detachment and large areas of capillary...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(88)90115-8
更新日期：1988-01-15 00:00:00
abstract：:We reviewed the results of vitreous surgery in 12 eyes of 12 patients with tractional macular detachment from Toxocara canis. We performed a vitrectomy and membrane peeling in all eyes, with additional scleral buckling in four eyes. After a minimum of six months' follow-up, ten of the 12 eyes (83%) had complete retina...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73253-2
更新日期：1989-07-15 00:00:00
abstract：:We developed a method that models the effect of irregular corneal surface topography on corneal optical performance. A computer program mimics the function of an optical bench. The method generates a variety of objects (single point, standard Snellen letters, low contrast Snellen letters, arbitrarily complex objects) ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74602-1
更新日期：1990-04-15 00:00:00
abstract：PURPOSE:To describe the incidence of vision loss and of ocular complications attributable to birdshot retinochoroidopathy and to describe the association between therapy and the incidence thereof. DESIGN:Retrospective cohort study. METHODS: SETTING:Single-center, academic practice. STUDY POPULATION:Forty patients w...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.01.035
更新日期：2005-07-01 00:00:00
abstract：:We recorded visual-evoked cortical potentials before and after pars plana vitrectomy and intravitreal liquid silicone filling in 30 patients (30 eyes) with complicated retinal detachments without vascular eye disease or glaucoma. The flash- and flicker-evoked cortical potentials increased in amplitude in all cases. Of...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(88)90364-9
更新日期：1988-09-15 00:00:00
abstract：PURPOSE:To examine acquired pit of the optic nerve as a risk factor for progression of glaucoma. METHODS:In a retrospective longitudinal study, 25 open-angle glaucoma patients with acquired pit of the optic nerve were compared with a group of 24 open-angle glaucoma patients without acquired pit of the optic nerve. The...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)80185-8
更新日期：1998-04-01 00:00:00
abstract：:Two siblings had atrophic maculopathy associated with hereditary ataxia clinically defined as an olivopontocerebellar degeneration. The macular changes were suggestive of an early bull's-eye maculopathy in one case and of a late atrophic stage of bull's-eye maculopathy in the other. This suggests that concentric annul...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75125-6
更新日期：1980-11-01 00:00:00
abstract：PURPOSE:To evaluate the impact of cataract surgery on subfoveal choroidal thickness and central retinal thickness in the elderly. DESIGN:Prospective observational case series. METHODS:This cohort study included 29 eyes of 29 patients with senile cataract, but no previous ocular surgery or other ocular abnormality. Al...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.05.016
更新日期：2014-09-01 00:00:00
abstract：:Six patients had peripheral to midperipheral pale yellow retinal exudates typical of acute retinal necrosis syndrome but which extended gradually to the posterior pole and remained isolated without becoming confluent. These exudates resulted in localized retinochoroidal degeneration without retinal detachment, in cont...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(88)90047-5
更新日期：1988-06-15 00:00:00
abstract：PURPOSE/METHODS:A 49-year-old woman with a left orbital mass was referred to an orbital clinic. Clinical investigation suggested a lacrimal gland lesion and the patient underwent lateral orbitotomy and excisional biopsy for a suspected pleomorphic adenoma in the lacrimal gland. RESULTS/CONCLUSION:Histopathologic evalu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73823-1
更新日期：1995-01-01 00:00:00
abstract：:We prospectively studied 76 patients to analyze the effectiveness of peribulbar anesthesia during strabismus surgery. The patients, ranging in age from 14 to 77 years, were given anesthesia with standard preoperative medication and a peribulbar injection of a mixture of 2% mepivacaine hydrochloride and hyaluronidase. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72440-7
更新日期：1990-06-15 00:00:00
abstract：PURPOSE:To evaluate the in vivo durability of the surface and optical properties of the implantable Collamer lens (ICL). DESIGN:Retrospective case series. METHODS:We included patients who developed cataracts after having undergone ICL implantation from March 2003 to May 2014 and underwent ICL explantation followed by...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.06.025
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:To evaluate the microbiology of pediatric orbital cellulitis associated with sinusitis. DESIGN:Retrospective review of medical records of pediatric patients treated for orbital cellulitis. METHODS:All pediatric patients treated for orbital cellulitis associated with sinusitis at Texas Children's Hospital betw...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.04.049
更新日期：2007-10-01 00:00:00
abstract：PURPOSE:To report a patient with unilateral vision loss and neovascular glaucoma after attempted superior ophthalmic vein embolization in the treatment of a carotid-cavernous sinus fistula. METHODS:A 69-year-old man with a history of a left dural carotid-cavernous sinus fistula underwent attempted treatment with super...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71711-8
更新日期：1997-12-01 00:00:00
abstract：PURPOSE:To compare the extent of mucosal margins remaining unsutured at the end of external dacryocystorhinostomy (DCR) using single or double flap techniques and to evaluate the influence on outcome. DESIGN:Prospective, consecutive case series. METHODS:The number and length of mucosal margins remaining unsutured at ...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ajo.2004.06.032
更新日期：2004-11-01 00:00:00
abstract：PURPOSE:To determine the trends and disparities in inpatient costs for eye trauma in the United States from 2001 through 2014. DESIGN:Retrospective population-based cross-sectional study. METHODS:National Inpatient Sample, a representative sample of U.S. hospital discharges, was used to determine costs of eye trauma ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2019.05.021
更新日期：2019-11-01 00:00:00
abstract：:We compared the intraocular pressure in 150 urban household contacts of patients with Hansen's disease and 132 endemic control subjects from an urban population in Karachi, Pakistan, who were matched in regard to race, age, gender, and socioeconomic status. The mean intraocular pressure in the upright position was 12....
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71861-6
更新日期：1992-10-15 00:00:00
abstract：PURPOSE:Current screening of potential corneal donors for human immunodeficiency virus type 1 (HIV-1) involves serologic detection of antibodies to the virus. However, this approach cannot detect infection during the seronegative window period of the disease. We therefore evaluated the polymerase chain reaction (PCR) a...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72113-0
更新日期：1996-10-01 00:00:00
abstract：:A 68-year-old white man with a documented family history of Reis-Bücklers' corneal dystrophy had a penetrating keratoplasty of the right eye in 1962. In 1977, vision decreased and foreign body sensation returned. Examination indicated a Reis-Bücklers' dystrophy that had appeared in the graft 15 years after the transpl...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75256-0
更新日期：1978-04-01 00:00:00
abstract：:Nerve fiber counts of 16 normal human optic nerves from subjects aged 3.5 to 82 years showed a significant effect of age (P = .0207). The delay between death or enucleation and fixation also significantly affected the result (P = .0078). The mean (+/- S.E.M.) count for the 16 nerves was 1,244,005 +/- 20,033 fibers, gi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90509-9
更新日期：1984-06-01 00:00:00
abstract：PURPOSE:To provide a systematic classification of fundus autofluorescence (FAF) patterns in patients affected by Best vitelliform macular dystrophy. DESIGN:Cross-sectional prospective study. METHODS:Patients affected by Best vitelliform macular dystrophy at different stages of the disease were prospectively enrolled ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.07.026
更新日期：2014-11-01 00:00:00
abstract：PURPOSE:To optimize the method of treating choroidal neovascularization (CNV) associated with age-related macular degeneration (AMD). DESIGN:Experimental study and interventional case series. METHODS:The parameters associated with locating and then photocoagulating CNV feeder vessels were identified and optimized usi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01579-9
更新日期：2002-08-01 00:00:00
abstract：:T-cell and B-cell lymphocyte subpopulations, monocytes, granulocytes, and immunoglobulin receptors were measured with monoclonal antibodies and flow cytometric techniques in the peripheral blood of 266 patients with posterior uveal melanoma before therapy. Statistically significant differences were found in T-helper/i...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90587-8
更新日期：1986-02-15 00:00:00
abstract：PURPOSE:To determine whether cataract in patients with atopic dermatitis is associated with higher levels of aqueous flare or cells. METHODS:In a prospective study, 35 consecutive patients examined during a 6-month period at the atopic dermatitis service in a university hospital underwent standardized ophthalmologic e...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)71641-1
更新日期：1997-07-01 00:00:00
abstract：PURPOSE:To report the long-term outcomes of intravitreal anti-vascular endothelial growth factor (VEGF) treatment for diabetic macular edema (DME) in a real-world clinical setting and to assess the efficacy of subsequent alternative treatments in eyes with suboptimal response to anti-VEGF. DESIGN:Retrospective interve...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2018.08.004
更新日期：2018-11-01 00:00:00
abstract：:Extraocular bacterial culture was performed in 100 patients with hypovitaminosis A xerophthalmia. There was corneal ulceration in 29 cases and corneal perforation in 22 cases. Eighty-six percent of the patients harbored frankly pathogenic bacteria (46 patients) and potentially pathogenic bacteria (40 patients). All bu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90399-2
更新日期：1975-10-01 00:00:00
abstract：:A 6-year-old boy with a visual acuity of 6/30 (20/100) in each eye had a diffuse corneal epithelial disruption that was most severe in the interpalpebral area. Corneal anesthesia was demonstrated with the Cochet-Bonnet aesthesiometer. Artificial tears, lubricant ointments, and taping of the eyelids were unsuccessful i...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)77729-3
更新日期：1978-03-01 00:00:00
abstract：:We treated two patients with Crohn's disease and one patient with ulcerative colitis who developed headache, papilledema, and intracranial hypertension (pseudotumor cerebri) during corticosteroid withdrawal. One had four separate episodes with corticosteroid withdrawal, which suggested a causal relationship. This asso...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73145-9
更新日期：1994-03-15 00:00:00
abstract：PURPOSE:To study the appearance of margins of geographic atrophy in high-resolution optical coherence tomography (OCT) images and to correlate those changes with fundus autofluorescence (FAF) imaging. DESIGN:Retrospective, observational case study. METHODS:Patients with geographic atrophy secondary to dry age-related...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2009.04.022
更新日期：2009-09-01 00:00:00
