Abstract:
:Fifty-five patients with primary open-angle glaucoma and early glaucomatous damage who had medical therapy and laser trabeculoplasty were followed up for four to 11 years or until progressive glaucomatous damage was documented. Factors associated with the stability or progression of glaucoma were evaluated. Eyes with mean intraocular pressure higher than 21 mm Hg during the follow-up period uniformly had progressive glaucomatous changes. Conversely, eyes with mean intraocular pressure less than 17 mm Hg remained stable, and approximately half of the eyes with mean intraocular pressure between 17 and 21 mm Hg had progressive glaucomatous changes. Patients who remained stable were slightly younger than those with progressive glaucomatous changes (P less than .05), but initial optic nerve head appearance, initial visual field findings, number of medicines used, medical history, and patient gender or race were not statistically associated with stability or progression of the glaucoma. These findings reinforce the importance of intraocular pressure control in primary open-angle glaucoma and the need to identify other markers that help determine the proper level of intraocular pressure for individual patients.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Mao LK,Stewart WC,Shields MBdoi
10.1016/s0002-9394(14)76896-5subject
Has Abstractpub_date
1991-01-15 00:00:00pages
51-5issue
1eissn
0002-9394issn
1879-1891pii
S0002-9394(14)76896-5journal_volume
111pub_type
杂志文章abstract:PURPOSE:To examine if myopia is a risk factor for age-related cataract. DESIGN:Systematic review and meta-analysis. METHODS:A systematic review of the literature was performed using PubMed and Embase from their inception to March 2013 for population-based studies with data on myopia and age-related cataract, includin...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ajo.2013.06.005
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:To correlate fractal dimension (FD) of the retinal vasculature with the extent of retinal nonperfusion area in diabetic retinopathy (DR) on ultrawide-field fluorescein angiography (FA). DESIGN:Cross-sectional study. METHODS:Baseline Optos 200Tx ultrawide-field FA images of 80 eyes with DR from the DAVE (NCT01...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ajo.2019.08.015
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To evaluate the ocular hypotensive effect and safety of carteolol hydrochloride 1% vs timolol maleate 0.5%. METHODS:One hundred seventy-six patients with ocular hypertension or primary open-angle glaucoma were randomly assigned to receive either carteolol 1% twice a day or timolol maleate 0.5% solution twice a...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0002-9394(14)70865-7
更新日期:1997-10-01 00:00:00
abstract:PURPOSE:To assess the effects of sustained gazing on visual function of dry eye patients. DESIGN:Prospective, comparative before-and-after study. METHODS:A total of 176 patients with dry eye and 33 control subjects ≥50 years old were included. Dry eye symptomatology along and clinical parameters were assessed. Out-lo...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.10.009
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:To compare tear protein markers between normal subjects and patients with dry eye (DE) and high and low lymphotoxin-alpha (LT-α) levels. DESIGN:Prospective cross-sectional study. METHODS:Patients with DE were divided into low (≤700 pg/mL) and high (>700 pg/mL) LT-α groups. Twelve protein markers were measured...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.03.013
更新日期:2020-09-01 00:00:00
abstract::Ten patients with Stargardt's disease and 14 with fundus flavimaculatus underwent thorough ophthalmic examinations, retinal photography, and, when possible, fluorescein angiography. Retinal function was also assessed by static and kinetic perimetry, the Farnsworth-Munsell 100-hue test, electro-oculography, and electro...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(83)90455-5
更新日期:1983-07-01 00:00:00
abstract:PURPOSE:To evaluate the relationship between rates of change on frequency doubling technology (FDT) perimetry and longitudinal changes in quality of life (QoL) of glaucoma patients. DESIGN:Prospective observational cohort study. METHODS:One hundred fifty-two subjects (127 glaucoma and 25 healthy) were followed for an...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2015.04.007
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:To determine if the use of oral contraceptive pills (OCP) and other hormonal contraceptives are associated with a higher incidence of idiopathic intracranial hypertension (IIH). DESIGN:Retrospective, population-based, case-control study. METHODS:Setting: Female IIH patients evaluated between January 1, 1990, ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.09.014
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To present a case of choroidal neovascularization associated with sympathetic ophthalmia successfully treated with photocoagulation. DESIGN:Interventional case report. METHODS:A 41-year-old man with a history of penetrating injury right eye, as well as sympathetic ophthalmia left eye, developed a classic chor...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(01)01044-3
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:Although congenital epiblepharon is a relatively common condition, particularly in Asians, acquired lower eyelid epiblepharon is rare. METHOD:We examined an 8-year-old boy who developed unilateral lower eyelid epiblepharon after a subciliary incisional approach for repair of a zygomatico-orbital fracture. RES...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72084-7
更新日期:1996-09-01 00:00:00
abstract:PURPOSE:To highlight the possible role of indocyanine green angiography in predicting future exudative changes in eyes that are candidates for drusen laser treatment. METHODS:In a 56-year-old woman, fluorescein and indocyanine green angiography were performed before drusen laser treatment. RESULTS:The treated eye had...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70875-x
更新日期:1997-10-01 00:00:00
abstract:PURPOSE:To ascertain deformation of the optic nerve head (ONH) and peripapillary tissues caused by horizontal duction. DESIGN:Prospective, experimental study. METHODS:Optical coherence tomography of the ONH region was performed in 23 eyes of 12 normal volunteers in central gaze and increasing (10, 20, and 30 degrees)...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.10.001
更新日期:2017-02-01 00:00:00
abstract:PURPOSE:Intraindividual comparison of tilt and decentration of three-piece foldable intraocular lenses (IOLs) with 6-mm optics and different edge design and material. DESIGN:Prospective randomized study. METHODS:Twenty-five patients with senile cataract (group I) received a foldable silicone, sharp optic edge IOL in ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ajo.2005.07.026
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:To examine the effect of basic fibroblast growth factor on induced choriocapillaris atrophy in vivo. METHODS:Choriocapillaris atrophy was surgically induced in rabbits by a hydraulic retinal detachment followed by debridement of the retinal pigment epithelium under the detached retina. Three concentrations of ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(01)00921-7
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:To describe a group of patients with dense visual field defects following macular hole surgery. METHODS:Nine (7%) of 125 patients reviewed noted onset of dense visual field defects following uncomplicated vitrectomy with gas-fluid exchange for the treatment of macular hole. Patient records were reviewed to inv...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72064-1
更新日期:1996-09-01 00:00:00
abstract:PURPOSE:To report a patient who was initially examined with optic tract syndrome caused by a focal metastasis to the lateral geniculate body and optic tract. METHOD:Case report. RESULTS:A 44-year-old woman with metastatic breast cancer was initially examined with normal central visual acuity, afferent pupillary defec...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)80251-7
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:To determine whether the hepatocyte growth factor is increased in the vitreous of patients with proliferative vitreoretinopathy. METHODS:We assayed hepatocyte growth factor levels by enzyme-linked immunosorbent assay (ELISA) in vitreous samples from 65 consecutive eyes (65 patients) with proliferative vitreore...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00360-3
更新日期:2000-05-01 00:00:00
abstract:PURPOSE:To report a case of pityriasis rubra pilaris (PRP)-induced bilateral lower eyelid cicatricial ectropion that resolved with systemic low-dose methotrexate. DESIGN:Observational case report. METHODS:A retrospective case review of a patient with cicatricial ectropion caused by PRP. RESULTS:A 82-year-old female ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.11.038
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:To assess the safety of VR 3D headset (virtual reality 3-dimensional binocular-stereoscopic near-eye display) use in young children. Product safety warnings that accompany VR headsets ban their use in children under age 13 years. DESIGN:Prospective, interventional, before-and-after study. METHODS:Recordings w...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.07.020
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To treat a 30-year-old man with a ventriculoperitoneal shunt who had progressive visual loss. METHODS:The patient underwent computed tomographic and magnetic resonance imaging scans and ocular examination. RESULTS:He was diagnosed with ventriculoperitoneal shunt failure despite the lack of ventriculomegaly on...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71980-4
更新日期:1996-07-01 00:00:00
abstract:PURPOSE:To evaluate the relationships among age-related macular degeneration (AMD), mortality, and biomarkers of systemic inflammation in patients with acquired immunodeficiency syndrome (AIDS). DESIGN:Case-control study. METHODS:In participants with intermediate-stage AMD at enrollment in the Longitudinal Study of t...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.12.002
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:To describe the long-term surgical course of patients with open globe injury. DESIGN:Retrospective case series. METHODS:Patients with open globe injuries (848 in total) treated surgically at the Massachusetts Eye and Ear Infirmary between 2000 and 2009 were retrospectively reviewed. Data from presentation, in...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2011.10.013
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:To evaluate the possible toxicity of indocyanine green (ICG) dye in macular hole surgery by comparing functional results after successful surgeries performed with and without staining. DESIGN:Prospective observational case series. METHODS:In a study conducted at our department, 30 eyes of 29 patients with idi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.05.054
更新日期:2006-11-01 00:00:00
abstract::A 50-year-old man sustained severe head injury, including a brief loss of consciousness, in an automobile accident. Skull X-ray films disclosed a fracture of the right superior orbit. Computed tomography demonstrated pneumocephalus and extension of the fracture into the sella turcica. Perimetric testing disclosed a bi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(81)90778-9
更新日期:1981-08-01 00:00:00
abstract:PURPOSE:Although the association of cystoid macular edema with peripheral choroidal melanoma has been studied previously, the pathogenesis of cystoid macular edema as evaluated by light and electron microscopy remains controversial. We evaluated the cause of cystoid macular edema at the retinal capillary level. METHOD...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73867-x
更新日期:1995-02-01 00:00:00
abstract:PURPOSE:To observe longitudinal changes in the corneal endothelium after pediatric cataract surgery with intraocular lens implantation. DESIGN:Prospective, longitudinal study. METHODS:settings: Iladevi Cataract and IOL Research Centre, Ahmedabad, India. study population: This study included 100 pediatric eyes undergo...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2012.02.018
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:To investigate the potential influences that affect visual acuity (VA) outcome in a clinic-based cohort of age-related macular degeneration (AMD) patients undergoing anti-vascular endothelial growth factor (anti-VEGF) treatment for choroidal neovascularization. DESIGN:Prospective interventional case series. M...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2011.09.013
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:To determine the origin of scleritis, uveitis, and glaucoma in a boy with fever, sore throat, joint pains, and malaise. METHODS:The patient underwent extensive hematologic, serologic, rheumatologic, and radiologic examinations. RESULTS:The patient recovered after extensive medical therapy. He met the Jones cr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72676-5
更新日期:1995-10-01 00:00:00
abstract::We followed up 32 eyes of 32 patients with early glaucoma (22 with capsular glaucoma and ten with simple glaucoma) who received laser trabeculoplasty as a primary therapy. These eyes were compared with a matched control group of 32 eyes treated with medication initially. The success rate (intraocular pressure below 22...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(87)90220-0
更新日期:1987-10-15 00:00:00
abstract::Of 150 consecutive cases of preretinal macular fibrosis that occurred predominantly in older subjects, 118 cases involved only one eye while 32 occurred binocularly. The ratio of women to men was 3:2. Visual acuity was usually 20/50 or better, and only four of 178 eyes had acuity below 20/200. The vast majority of les...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90605-4
更新日期:1975-03-01 00:00:00