Whipple disease presenting as posterior uveitis without prominent gastrointestinal symptoms.

Abstract:

PURPOSE:To describe the clinical presentation and course of Whipple disease in an adult. METHODS:A 34-year-old man with phthisis bulbi in the right eye secondary to uveitis-induced neovascular glaucoma presented with severe acute posterior uveitis in the left eye. He underwent esophagogastroduodenoscopy and jejunal biopsy for evaluation of anemia. The posterior uveitis was treated with a subtenon injection of triamcinolone. RESULT:The diagnosis of Whipple disease was confirmed by polymerase chain reaction analysis of the jejunal biopsy that demonstrated Tropheryma whippelii rDNA. CONCLUSION:Although Whipple disease is typically evident with malabsorption, it can also present as uveitis without prominent gastrointestinal symptoms.

journal_name

Am J Ophthalmol

authors

Nishimura JK,Cook BE Jr,Pach JM

doi

10.1016/s0002-9394(98)00084-1

subject

Has Abstract

pub_date

1998-07-01 00:00:00

pages

130-2

issue

1

eissn

0002-9394

issn

1879-1891

pii

S0002939498000841

journal_volume

126

pub_type

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