Abstract:
PURPOSE:To describe the clinical presentation and course of Whipple disease in an adult. METHODS:A 34-year-old man with phthisis bulbi in the right eye secondary to uveitis-induced neovascular glaucoma presented with severe acute posterior uveitis in the left eye. He underwent esophagogastroduodenoscopy and jejunal biopsy for evaluation of anemia. The posterior uveitis was treated with a subtenon injection of triamcinolone. RESULT:The diagnosis of Whipple disease was confirmed by polymerase chain reaction analysis of the jejunal biopsy that demonstrated Tropheryma whippelii rDNA. CONCLUSION:Although Whipple disease is typically evident with malabsorption, it can also present as uveitis without prominent gastrointestinal symptoms.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Nishimura JK,Cook BE Jr,Pach JMdoi
10.1016/s0002-9394(98)00084-1subject
Has Abstractpub_date
1998-07-01 00:00:00pages
130-2issue
1eissn
0002-9394issn
1879-1891pii
S0002939498000841journal_volume
126pub_type
杂志文章abstract::We recorded full-field electroretinograms from 47 males and 26 obligate carrier females with choroideremia. All males had responses that were subnormal with delayed cone b-wave implicit times or undetectable. Only four of 26 females had abnormal electroretinographic responses but 25 of 26 were identified by ophthalmos...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(86)90832-9
更新日期:1986-03-15 00:00:00
abstract:PURPOSE:To describe the principles, capabilities, and applications of confocal microscopy in vivo in ophthalmology. DESIGN:Perspective, literature review, and commentary. METHODS:Review and synthesis of selected recent literature, with interpretation and perspective. RESULTS:Confocal microscopy imaging has led to a ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/j.ajo.2009.06.022
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:To evaluate the long-term risk of endothelial rejection, graft survival, and associated factors following penetrating keratoplasty (PK) for keratoconus, with and without prior resolved corneal hydrops. DESIGN:Retrospective cohort study. METHODS:Primary outcome measures were endothelial rejection-free survival...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.07.001
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To determine whether central corneal thickness (CCT) is a risk factor for visual field loss development among patients diagnosed with preperimetric glaucomatous optic neuropathy (GON). DESIGN:Observational cohort study. METHODS:The study included 98 eyes of 98 patients with GON, with a mean follow-up time of ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00484-7
更新日期:2003-11-01 00:00:00
abstract::A 14-year-old boy was stabbed above the left eye and had subsequent loss of both retinal and choroidal perfusion to the posterior segment. Ophthalmoscopic examination ten days after the injury disclosed intense nerve fiber layer edema, most prominent in the posterior pole, and absence of a cherry-red spot. Intravenous...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90666-4
更新日期:1979-10-01 00:00:00
abstract:PURPOSE:To evaluate for which range of refractive error the optic disk size depends on, or is independent of, the refractive error. DESIGN:Clinical observational study. METHODS:The study included 1999 eyes of 1011 subjects with a mean refractive error of -0.97 +/- 2.72 diopters (range, -24.25 to +9.4 diopters). Optic...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.07.047
更新日期:2005-02-01 00:00:00
abstract::We assessed 81 patients in four groups (normal, low- and high-risk ocular hypertension, and early glaucoma) with the standard Octopus G1 central visual field program in addition to two quantitative programs, PFN (peripheral field-nasal) and PFT (peripheral field-temporal), designed for this study to test the nasal and...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(88)90831-8
更新日期:1988-08-15 00:00:00
abstract:PURPOSE:To evaluate the effect on peripheral visual field defects occurring after macular hole surgery of passing air that is used for fluid-air exchange through water before infusion to the eye. METHODS:We used Goldmann perimetry to measure the visual fields of patients who underwent vitrectomy to manage idiopathic f...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00287-6
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:To investigate in open-angle glaucoma the focal macular photopic negative response and spectral-domain optical coherence tomography measurements of retinal thicknesses in the superior and inferior macula. DESIGN:Comparative case series. METHODS:We studied 63 eyes of 63 patients with open-angle glaucoma and 41...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2010.09.018
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:To determine the types and incidence of caruncular lesions and to investigate the correlation between clinical and histologic diagnosis. DESIGN:Retrospective, observational case series. METHODS:Records of patients with a lesion of the caruncle that was excised and submitted to our ocular pathology department ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.04.035
更新日期:2006-09-01 00:00:00
abstract::We reviewed the charts of 29 patients with large subretinal hemorrhages involving the center of the fovea to evaluate factors that might be prognostic of visual outcome. The average final visual acuity was 20/480 with a mean follow-up of three years. Patients with thick hemorrhages (causing an obvious elevation of the...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75575-8
更新日期:1990-01-15 00:00:00
abstract:PURPOSE:To report long-term clinical outcomes of deep anterior lamellar keratoplasty (DALK) in patients with keratoconus. DESIGN:Retrospective noncomparative interventional study. METHODS:setting: Single center. patients: Total of 158 eyes/150 consecutive patients with keratoconus with postoperative follow-up time eq...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2014.11.033
更新日期:2015-03-01 00:00:00
abstract::Seventeen patients (ten women and seven men, 23 to 72 years old) with stromal herpetic disease were treated with topical and oral acyclovir for 14 days. Of the 12 patients with disciform edema, five showed minimal improvement, four showed no change, and three showed worsening of their disease. Of the five patients wit...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(84)90237-x
更新日期:1984-11-01 00:00:00
abstract:PURPOSE:To compare race-related differences in estimated rate of change of Bruch's membrane opening-minimum rim width (BMO-MRW) and circumpapillary retinal nerve fiber layer thickness (RNFLT) in healthy, glaucoma suspect, and glaucoma eyes of individuals of European (ED) and African descent (AD). DESIGN:Prospective co...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.08.050
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of hyperdry amniotic membrane (AM) patching attached using a tissue adhesive for corneal perforations and glaucoma filtering bleb leaks. DESIGN:Prospective, noncomparative, interventional case series. METHODS:Five eyes of 5 patients (glaucoma bleb leaks, 2 eyes; corneal perforations, ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.03.030
更新日期:2009-09-01 00:00:00
abstract:PURPOSE/METHODS:We observed a clinicopathologic correlation of a case of adenocarcinoma of the retinal pigment epithelium. RESULTS/CONCLUSIONS:The ultrasonographic findings of this tumor demonstrated a collar button profile with high internal reflectivity. The ultrasonographic characteristics in this case reflected th...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73887-5
更新日期:1995-02-01 00:00:00
abstract:PURPOSE:To examine the occurrence and outcome of methicillin-resistant Staphylococcus aureus ophthalmologic infections in a newborn intensive care unit cohort. DESIGN:Noninterventional case series. METHODS:Over a 13-month period, 29 neonates were colonized with methicillin-resistant S. aureus in a newborn intensive c...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.02.019
更新日期:2006-07-01 00:00:00
abstract::Ciprofloxacin is a potent fluoroquinolone antibiotic with in vitro activity against many significant gram-positive and gram-negative ocular pathogens. A review of the experimental studies of this antibiotic shows bactericidal activity, a broad antimicrobial spectrum, and a low incidence of resistance. The growing body...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1991-10-01 00:00:00
abstract::We treated 23 consecutive cases of giant retinal tears with inverted retinal flaps. We used pars plana vitrectomy together with an intravitreal bubble to unfold the posterior retinal flap, combined with cryotherapy to cause a chorioretinal adhesion and a broad scleral buckle. The vitrectomy was done after applying cry...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(84)90132-6
更新日期:1984-10-15 00:00:00
abstract::During the last four years we treated 82 consecutive patients (83 eyes) with retinal detachments complicated by proliferative vitreoretinopathy. We used pars plana vitrectomy combined with a broad scleral buckle, cryotherapy to the retinal breaks, and a temporary intraocular gas bubble. The retina was successfully rea...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(84)90683-4
更新日期:1984-12-15 00:00:00
abstract:PURPOSE:To report an uncommon case of multifocal choroiditis as the result of disseminated Cryptococcus neoformans infection in a patient who is HIV-positive. DESIGN:Interventional case report. METHODS:A 27-year-old HIV-positive woman with fever, headache, and vomiting was examined. Lumbar puncture was performed and ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.03.024
更新日期:2006-08-01 00:00:00
abstract:PURPOSE:To report a case of unilateral proptosis and chronic pansinusitis in which the diagnosis of pneumocele was made. DESIGN:Observational case report. METHODS:A retrospective chart review was made. RESULTS:A 52-year-old man with chronic pansinusitis presented with a 5-mm proptosis and a larger palpebral fissure ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.02.054
更新日期:2004-07-01 00:00:00
abstract::We studied the behavior of intraocular pressure in glaucoma suspects randomly selected to receive either topical timolol or no treatment over the course of a long-term prospective follow-up study. All patients who after six years of follow-up showed no localized field defects or disk changes, or whose pressures were n...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-9394(89)90490-x
更新日期:1989-05-15 00:00:00
abstract::We studied the ultrastructure of the four types of dysplastic rosettes and compared them with retinoblastoma rosettes. Dysplastic rosettes have morphologic characteristics intermediate between the normal photoreceptor layer and retino-blastoma rosettes; Müller cells contribute to the formation of dysplastic but not ne...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)77107-7
更新日期:1978-05-01 00:00:00
abstract:PURPOSE:To evaluate the behavior and attitudes among ophthalmology trainees toward pharmaceutical promotions. DESIGN:Questionnaire survey. METHODS:A questionnaire on behavior and attitudes toward interactions with pharmaceutical representatives was distributed to 110 ophthalmology residency programs in the United Sta...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.05.011
更新日期:2009-10-01 00:00:00
abstract::We conducted a two-part study to determine whether any positive association between the use of allopurinol and the development of cataracts could be demonstrated. Study 1 included 251 Boston-area patients hospitalized for cataract and 753 matched controls. Two cataract patients were regular allopurinol users as compar...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(84)90328-3
更新日期:1984-09-15 00:00:00
abstract:PURPOSE:Intraindividual comparison of tilt and decentration of three-piece foldable intraocular lenses (IOLs) with 6-mm optics and different edge design and material. DESIGN:Prospective randomized study. METHODS:Twenty-five patients with senile cataract (group I) received a foldable silicone, sharp optic edge IOL in ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ajo.2005.07.026
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:To compare the intraocular pressure)-lowering effect and side effects of latanoprost 0.005% once daily with unoprostone 0.12% twice daily. METHODS:Sixty patients with primary open-angle glaucoma or ocular hypertension were randomized to receive either latanoprost once daily in the evening and placebo once dail...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0002-9394(00)00943-0
更新日期:2001-05-01 00:00:00
abstract:PURPOSE:To compare the effects of extracapsular cataract extraction with posterior chamber intraocular lens (ECCE/PC-IOL) vs intracapsular cataract extraction with aphakic glasses (ICCE-AG) on everyday visual functioning and quality of life. METHODS:In a nonmasked randomized controlled clinical trial, 3,400 bilateral ...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-9394(99)80231-1
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:This study is a systematic exploration of why some patients with glaucoma continue to lose visual field long after therapeutic normalization of their increased intraocular pressures. METHODS:Three cases of glaucoma are described that had increased intraocular pressures and good initial visual fields. RESULTS:...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75421-2
更新日期:1996-05-01 00:00:00