Abstract:
PURPOSE:To evaluate the behavior and attitudes among ophthalmology trainees toward pharmaceutical promotions. DESIGN:Questionnaire survey. METHODS:A questionnaire on behavior and attitudes toward interactions with pharmaceutical representatives was distributed to 110 ophthalmology residency programs in the United States. Responses were collected and analyzed. RESULTS:One hundred and twenty-two responses were received. Most (87%) respondents reported seeing pharmaceutical representatives visiting their program at least once every 1 to 2 months. Most respondents reported having accepted gifts from them. Although only 26% of trainees have changed prescribing behavior based on information provided by pharmaceutical representatives, 77% did so because of available medicine samples. Trainees tended to consider their peers more susceptible than themselves to the influence of pharmaceutical promotions. When asked to rate their agreement to questionnaire statements, with 5 meaning strongly agree and 1 meaning strongly disagree, the average score for "Pharmaceutical representatives influence my prescribing" was only 2.72, compared with 3.67 for "Pharmaceutical representatives influence other physicians' prescribing" (P < .0001). Although half of the trainees (51%) acknowledged that their programs have guidelines or policies regarding interactions with the pharmaceutical industry, only 28% reported having received training in this area. CONCLUSIONS:Ophthalmology trainees have frequent encounters with pharmaceutical representatives. The trainees tend to consider their peers more susceptible than themselves to the influence of pharmaceutical promotions. Pharmaceutical representatives seem able to change prescribing practices among trainees they contact by providing information or leaving drug samples. Many trainees have not received any education in this area from their programs.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Wang Y,Adelman RAdoi
10.1016/j.ajo.2009.05.011subject
Has Abstractpub_date
2009-10-01 00:00:00pages
619-622.e3issue
4eissn
0002-9394issn
1879-1891pii
S0002-9394(09)00349-3journal_volume
148pub_type
杂志文章abstract:PURPOSE:The purpose of this report is to review the clinical variations and natural course of Coats disease, using strict diagnostic guidelines. METHODS:In a retrospective, consecutive series, Coats disease was defined as idiopathic retinal telangiectasia with intraretinal or subretinal exudation without appreciable s...
journal_title:American journal of ophthalmology
pub_type:
doi:10.1016/s0002-9394(00)00883-7
更新日期:2001-05-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of adjunctive subconjunctival antibiotic injection in the treatment of acute postcataract extraction endophthalmitis. DESIGN:Retrospective cohort study. METHODS:Patients who presented with hand motions or better vision and received subconjunctival antibiotics (SC+ group) were compared...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2003.12.042
更新日期:2004-06-01 00:00:00
abstract:PURPOSE:To determine novel diagnostic parameters for keratoconus, and to assess the correlation between anterior and posterior corneal surfaces based on vectorial astigmatism analyses. DESIGN:Retrospective case-control study. METHODS:Six hundred and ninety-eight eyes of 698 patients were enrolled in the study. Health...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.04.008
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To correlate in vivo imaging to histology in an eye with macular atrophy owing to age-related macular degeneration (AMD; complete retinal pigment epithelium [RPE] and outer retinal atrophy [cRORA]) to evaluate the utility of new optical coherence tomography (OCT) suggested by previous histology. DESIGN:Case st...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.06.020
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:To evaluate the change in visual acuity and retinal appearance in patients after early initiation of intravitreal bevacizumab treatment for central retinal vein occlusion (CRVO). DESIGN:Retrospective, interventional case series. METHODS:Patients with CRVO of fewer than three months' duration receiving intravi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.07.038
更新日期:2007-12-01 00:00:00
abstract::We reviewed the records of 74 patients with exfoliation syndrome. Patients with exfoliation syndrome represented 12% of the current Glaucoma Clinic population. There were 40 unilateral and 34 bilateral cases. Thirteen percent of the patients who originally had unilateral exfoliation later developed exfoliation in the ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90054-9
更新日期:1980-04-01 00:00:00
abstract:PURPOSE:To report the features of idiopathic intracranial hypertension in prepubertal children, with emphasis on presentation, treatment, and outcome. METHODS:We retrospectively reviewed the charts of all patients 11 years and younger diagnosed with idiopathic intracranial hypertension at two university-affiliated med...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00386-9
更新日期:1999-02-01 00:00:00
abstract:PURPOSE:To develop patient-derived Pediatric Eye Questionnaires (PedEyeQ) to separately assess eye-related quality of life (ER-QOL) and functional vision in children with eye conditions. DESIGN:Questionnaire development study. METHODS:A total of 444 children (0 to <18 years old), across 10 diagnostic categories, were...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2019.01.001
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:To evaluate changes in postoperative refractive outcomes following combined phacoemulsification and pars plana vitrectomy for rhegmatogenous retinal detachment (RRD) compared with other retinal diseases. DESIGN:Retrospective observational case-control study. METHODS:A total of 55 patients who had combined sur...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2014.04.023
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:This study compared the outcomes after Descemet's membrane endothelial keratoplasty (DMEK) in pseudophakic patients with the outcomes after DMEK combined with cataract surgery (triple-DMEK) in patients with Fuchs' endothelial dystrophy (FED). DESIGN:Retrospective, single-institution, interventional, consecutiv...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.05.003
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To evaluate for which range of refractive error the optic disk size depends on, or is independent of, the refractive error. DESIGN:Clinical observational study. METHODS:The study included 1999 eyes of 1011 subjects with a mean refractive error of -0.97 +/- 2.72 diopters (range, -24.25 to +9.4 diopters). Optic...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.07.047
更新日期:2005-02-01 00:00:00
abstract:PURPOSE:To investigate the relationship between intraretinal macular hemorrhage and visual acuity outcomes in eyes with central retinal vein occlusion or hemiretinal vein occlusion managed with aflibercept, bevacizumab, or observation. DESIGN:Retrospective analysis of data from 2 randomized clinical trials. METHODS:A...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.08.030
更新日期:2020-08-20 00:00:00
abstract::Leber's hereditary optic neuropathy is caused by a single nucleotide change in the mitochondrial deoxyribonucleic acid (mtDNA). Each cell contains thousands of mitochondrial DNA molecules. We demonstrated that in certain isolated instances, the proband and close maternal lineage relatives can have mixtures of mutant a...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72429-8
更新日期:1990-06-15 00:00:00
abstract:PURPOSE:In previous studies of fungal keratitis (FK) from temperate countries, yeasts were the predominant isolates, with ocular surface disease (OSD) being the leading risk factor. Since the 2005-2006 outbreak of contact lens (CL)-associated Fusarium keratitis, there may have been a rise in CL-associated filamentary F...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.05.021
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:To evaluate the ocular biometric parameters associated with intraocular pressure (IOP) reduction after phacoemulsification. DESIGN:Prospective, observational case series. METHODS:The study included 999 patients who had undergone uncomplicated phacoemulsification. IOP and ocular biometric parameters were check...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2013.02.003
更新日期:2013-07-01 00:00:00
abstract::We modified trabeculo-iridocyclosclerectomy in a technique for en bloc excision of anterior uveal tumor. A trabeculectomy-type of approach was used, which allowed excision of a rectangular block of sclera, cornea, and trabeculum with attached uveal tissue containing the tumor. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90657-3
更新日期:1979-09-01 00:00:00
abstract::During a two-year period a randomly selected age-stratified sample of subjects 65 years old and older living in Gisborne, New Zealand, was examined by an ophthalmologist to investigate visual acuity and the prevalence of the major disorders of vision in old age. A total of 481 subjects (a response rate of 86.2%) compl...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(82)90073-3
更新日期:1982-08-01 00:00:00
abstract::To assess the efficacy and safety of twice-daily administration of nedocromil sodium 2% ophthalmic solution, we performed a multicenter study involving 140 patients with seasonal allergic conjunctivitis. Subjects had a history of seasonal allergic conjunctivitis and positive results of a skin test to ragweed. The tria...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0002-9394(14)75754-x
更新日期:1992-01-15 00:00:00
abstract::We examined 242 healthy neonates. Five developed transient tonic downward deviation of the eyes and eight showed any resultant visual, systemic, or neurologic abnormality. However, five of the 22 children with neonatal skew deviation developed a subsequent comitant horizontal stabismus. Although transient supranuclear...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90292-5
更新日期:1980-05-01 00:00:00
abstract:PURPOSE:To evaluate the ocular surface inflammatory response to the presence of preservatives in nonselective beta-blocker eyedrops. DESIGN:Prospective, crossover, single-masked, randomized clinical study. METHODS:study population: Twenty primary open-angle glaucoma or ocular hypertensive patients were divided in two...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ajo.2004.08.028
更新日期:2005-01-01 00:00:00
abstract::In this prospective evaluation of the reliability and efficiency of an optimized visual field screening protocol for glaucoma, we tested 145 eyes (73 patients) with increased intraocular pressures to determine the location of early glaucomatous visual field defects. The field examination, which was used as a control, ...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:
更新日期:1981-10-01 00:00:00
abstract::Of two patients with type 5 hyperlipoproteinemia, one exhibited lipemia retinalis with multiple retinal hemorrhages and intraretinal lipid extravasations. Postmortem examination showed hemorrhages in the inner retinal layers and lipid deposits largely in the outer plexiform layer. Lipid within the walls of the retinal...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90661-9
更新日期:1976-07-01 00:00:00
abstract:PURPOSE:To evaluate long-term complications related to glaucoma drainage devices in patients undergoing Boston type 1 keratoprosthesis surgery. DESIGN:Retrospective case series. METHODS:All patients who underwent Boston type 1 keratoprosthesis surgery at the University of California, Davis, between 2004 and 2010 were...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2011.01.034
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:To examine the relationships of retinal vascular caliber with optic disc, macular, and retinal nerve fiber layer (RNFL) characteristics as measured with optical coherence tomography (OCT). DESIGN:Observational cross-sectional study. METHODS:This study included a subset of healthy children enrolled in the Sing...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.04.006
更新日期:2009-09-01 00:00:00
abstract::We examined a patient who had syphilitic perioptic neuritis, a rarely diagnosed inflammation of the sheaths of the optic nerves that may be confused with papilledema caused by brain tumor or pseudotumor cerebri. The visual acuity was typically normal, and the only visual-field abnormality was enlargement of the blind ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(81)90298-1
更新日期:1981-03-01 00:00:00
abstract:PURPOSE:To report bilateral optic disk edema and blindness as the unusual initial presentation of acute lymphocytic leukemia (ALL) in an adult. METHODS:A 19-year-old man presented with a history of headaches, back pain, and 10 days of worsening vision that progressed to blindness. Ocular examination revealed light per...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01465-4
更新日期:2002-07-01 00:00:00
abstract::The diameter of retinal arterioles, venules, and their macular branches was measured before and after macular laser photocoagulation in one eye each of six men and eight women with diabetic macular edema. The macular arteriolar branches constricted 20.2% (P < .001) and the venular branches constricted 13.8% (P < .001)...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73526-3
更新日期:1993-01-01 00:00:00
abstract::Extraocular bacterial culture was performed in 100 patients with hypovitaminosis A xerophthalmia. There was corneal ulceration in 29 cases and corneal perforation in 22 cases. Eighty-six percent of the patients harbored frankly pathogenic bacteria (46 patients) and potentially pathogenic bacteria (40 patients). All bu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90399-2
更新日期:1975-10-01 00:00:00
abstract:PURPOSE:To determine the safety and efficacy of AL-8309B (tandospirone) in the management of patients with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) and obtain standardized data on GA lesion growth progression. DESIGN:Prospective, controlled, double-masked, randomized, multicenter pha...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ajo.2015.08.024
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To describe rifabutin-associated uveitis with opacities in the inferior and posterior vitreous in three patients with acquired immunodeficiency syndrome. METHOD:Case reports of the three patients are presented. RESULTS:The patients, who were being treated with rifabutin and fluconazole, developed anterior and...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)72124-5
更新日期:1996-10-01 00:00:00