Abstract:
:We determined antigens of the major histocompatibility complex classes I, II, and III in 25 families of Mexican mestizo glaucomatous patients. Patients and family members were examined, and the predisposition of first-degree relatives to a corticosteroid-provocative test was determined. The results showed a high frequency of the HLA-DR3 antigen in patients with primary open-angle glaucoma compared with controls (32.5% vs 4.0%, P = .001, odds ratio = 10.25). We suggest that the increased presence of the HLA-DR3 antigen could be an important factor in the genetic susceptibility to glaucoma.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Gil-Carrasco F,Granados J,Barojas-Weber E,Gilbert-Lucido ME,Vargas-Alarcón Gdoi
10.1016/s0002-9394(14)72553-xsubject
Has Abstractpub_date
1994-12-15 00:00:00pages
744-8issue
6eissn
0002-9394issn
1879-1891pii
S0002-9394(14)72553-Xjournal_volume
118pub_type
杂志文章abstract::We examined two patients who had sudden decrease in vision after intranasal cocaine or methamphetamine abuse. A 38-year-old woman with a history of systemic arterial hypertension developed a central retinal artery occlusion four hours after intranasal use of cocaine. A 26-year-old woman had blurred vision and intraret...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73979-0
更新日期:1992-08-15 00:00:00
abstract:PURPOSE:To describe the relationship between the incidence of age-related macular degeneration (AMD) and nonsteroidal anti-inflammatory drug (NSAIDs) use. DESIGN:Prospective cohort study. METHODS:This study consisted of participants in the California Men's Health Study. Those who completed surveys in 2002-2003 and 20...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.01.012
更新日期:2018-04-01 00:00:00
abstract::Fluorescein angiography was safely performed in 100 consecutive cases of cataract extraction during the first postoperative week. Seventy-five percent of the 100 eyes had good quality fluorescein angiograms. Four eyes demonstrated cystoid macular edema. Therefore, the incidence of cystoid macular edema in the first we...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90126-4
更新日期:1976-05-01 00:00:00
abstract:PURPOSE:To evaluate outcomes of patients treated with intensive intravitreal therapy and to describe the evolution of quantitative real-time polymerase chain reaction (qPCR) in patients treated for acute retinal necrosis (ARN) syndrome. DESIGN:Retrospective observational case series. METHODS:This study included 25 ey...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.08.007
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To report a case of Bartonella henselae infection. DESIGN:Observational case report. METHODS:Review of the clinical, laboratory, photographic, and angiographic records of a patient with cat scratch disease associated with central retinal artery and vein occlusion, neovascular glaucoma, and severe vision loss....
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00784-0
更新日期:2004-01-01 00:00:00
abstract::We conducted a retrospective study of 107 penetrating keratoplasties in 99 eyes (99 patients) performed from 1970 to 1979 at the Wills Eye Hospital. The follow-up periods ranged from one to 12 years (median, three years). Overall, 86 of the 107 transplants (80%) remained clear and 63 eyes (59%) achieved good to excell...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(83)90384-7
更新日期:1983-05-01 00:00:00
abstract:PURPOSE:To investigate the role of corneal hysteresis (CH) as a risk factor for development of glaucoma. DESIGN:Prospective observational cohort study. METHODS:Two hundred and eighty-seven eyes of 199 patients suspected of having glaucoma were followed for an average of 3.9 ± 1.8 years. All eyes had normal visual fie...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.12.018
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:To report the response of calcification in choroidal melanoma after transpupillary thermotherapy. METHODS:Interventional case report. A 66-year-old male with a posterior uveal melanoma measuring 10 x 8 x 4.4 mm underwent infrared diode laser transpupillary thermotherapy three times, each 12 weeks apart. For ea...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(01)01186-2
更新日期:2001-12-01 00:00:00
abstract::We have constructed an ophthalmic fixation device that stabilizes an enucleated eye, and helps both in the pathologic examination of the eye and in ophthalmic practice surgery. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74929-3
更新日期:1980-09-01 00:00:00
abstract::We used a handheld disposable cautery for the diagnostic scraping of corneal ulcers. Sterility of the tip is obtained by activating the unit until the tip reaches a red-hot color and then allowing it to cool. The unit has a sturdy, well-defined tip, and is self-sterilizing, reusable, readily available, and simple to u...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75086-x
更新日期:1980-07-01 00:00:00
abstract:PURPOSE:We describe a case demonstrating a submacular deposition of triamcinolone acetonide (TA) after a TA-assisted vitrectomy for retinal detachment. DESIGN:Interventional case report. METHODS:A 48-year-old Japanese man with rhegmatogenous retinal detachment in his left eye underwent a TA-assisted vitrectomy, endol...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01917-7
更新日期:2003-02-01 00:00:00
abstract::A 33-year-old man had a sudden onset of night blindness 3 1/2 years after intestinal bypass surgery for morbid obesity. Ocular examination disclosed a probable Bitot's spot and electrophysiologic testing showed markedly impaired dark adaptation and subnormal electroretinography. After therapy with orally administered ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90164-6
更新日期:1980-06-01 00:00:00
abstract::Because determination of the differential light threshold of a visual field is a psychophysiologic test, the results can be subject to variation. This scatter measured during a single examination is usually called the short-term fluctuation. Increases of the short-term fluctuation were thought to occur primarily in ab...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(89)90667-3
更新日期:1989-04-15 00:00:00
abstract:PURPOSE:Encapsulation of the Ahmed glaucoma valve (AGV) plate is a common cause for postoperative elevation of intraocular pressure, especially in children. Many reports have described the outcomes of AGV revision in adults. However, the outcomes of AGV revision in children are poorly documented. The aim of this study ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.09.015
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:To investigate the magnitude, with-the-rule (WTR) or against-the-rule (ATR) orientation, and vector components (Jackson astigmatic vectors [J0 and J45] and blurring strength) of the anterior and posterior corneal astigmatism (ACA and PCA) in patients with keratoconus (KC) in a retrospective study, and to try to...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.03.051
更新日期:2016-07-01 00:00:00
abstract::To study further the transient increase in trabecular cell division within the first two days after laser trabeculoplasty in human corneoscleral explant organ cultures, we used a pulse-chase protocol in which immediately after laser treatment 3H-thymidine was added to the culture medium for 48 hours (the pulse period)...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(89)90805-2
更新日期:1989-01-15 00:00:00
abstract:PURPOSE:To report a new method to perform intraoperative video fluorescein angiography (VFA) using an optical fiber-free intravitreal surgery system (OFFISS) and retinal blood flow analysis during surgery. DESIGN:Observational case series. METHODS:Four eyes of four patients with macular edema as a result of branch re...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.06.079
更新日期:2004-12-01 00:00:00
abstract::We used monoclonal antibodies against specific T cell, B cell, and macrophage antigens to detect immune system cells in the vitreous gel of retinitis pigmentosa patients. Vitreous samples were obtained by biopsy from three patients and by dissection from eight postmortem donor eyes. All samples contained CD4, T helper...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(88)90050-5
更新日期:1988-06-15 00:00:00
abstract::Nonaccommodative convergence excess is a condition in which a patient has orthotropia or a small-angle esophoria or esotropia at distance and a large-angle esotropia at near, not significantly reduced by the addition of spherical plus lenses. The AC/A ratio, determined with the gradient method, is normal or subnormal....
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(86)90466-6
更新日期:1986-01-15 00:00:00
abstract:PURPOSE:To describe the motivations, expectations, and other factors men with X-linked retinoschisis (XLRS) consider when making decisions to participate in an early phase ocular gene therapy clinical trial. DESIGN:Qualitative interview study. METHODS:Men with XLRS who were considering participation in a phase I/IIa ...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ajo.2019.03.009
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:To clinically validate and ascertain the repeatability of a short questionnaire for dry eye syndrome (DES), consisting of two questions pertaining to symptoms (dryness and irritation) and one question regarding previous history of clinically diagnosed DES. DESIGN:Clinical validation study with repeated assessm...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.02.038
更新日期:2006-07-01 00:00:00
abstract:PURPOSE:To evaluate the ocular surface inflammatory response to the presence of preservatives in nonselective beta-blocker eyedrops. DESIGN:Prospective, crossover, single-masked, randomized clinical study. METHODS:study population: Twenty primary open-angle glaucoma or ocular hypertensive patients were divided in two...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ajo.2004.08.028
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To report the visual outcome of multiple laser treatments for macular edema attributable to branch retinal vein occlusions (BRVO) and to determine if any prognostic factors exist for improvement. DESIGN:Retrospective chart review. METHODS:A private practice with four vitreoretinal surgeons performed laser tre...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.11.011
更新日期:2005-04-01 00:00:00
abstract::Topical ketoconazole (2% ointment three times per day for three weeks) markedly reduced the severity of keratitis produced with Candida albicans inoculation in the right eyes of 20 rabbits. Clinical scores of affected eyes were significantly lower in the treated eyes than in the controls, which consisted of the 20 ino...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(86)90084-x
更新日期:1986-10-15 00:00:00
abstract:PURPOSE:To demonstrate that hairy cell leukemia may involve the eye. METHODS:We examined a patient who had a unique ocular manifestation of hairy cell leukemia with severe panuveitis in one eye and leukemic retinopathy in the fellow eye. RESULTS:Therapy with 2-chloro-deoxy-adenosine, a drug recently introduced for tr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70543-4
更新日期:1996-01-01 00:00:00
abstract:PURPOSE:To compare the demographics and ocular characteristics, including anterior segment optical coherence tomography images and zonular instability, in eyes with a history of acute angle closure (AAC) attack and subsequent cataract surgery. DESIGN:Retrospective case-control study. METHODS:A total of 68 eyes of 56 ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.09.003
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:To report a case of unilateral proptosis and chronic pansinusitis in which the diagnosis of pneumocele was made. DESIGN:Observational case report. METHODS:A retrospective chart review was made. RESULTS:A 52-year-old man with chronic pansinusitis presented with a 5-mm proptosis and a larger palpebral fissure ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.02.054
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:To assess retinal nerve fiber layer (RNFL) and macular thickness using optical coherence tomography (OCT) on HIV-infected patients without ocular manifestations and to correlate these findings with frequency-doubling technology perimetry (FDT). DESIGN:Cross-sectional study. METHODS:setting: Single center. stu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.11.026
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:To develop a model for estimating the global risk of disease progression in patients with ocular hypertension and to calculate the "number-needed-to-treat" (NNT) to prevent progression to blindness as an aid to practitioners in clinical decision making. DESIGN:Development of a mathematical model for estimating...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/j.ajo.2004.04.054
更新日期:2004-09-01 00:00:00
abstract:PURPOSE:To report a case of bilateral acute retinal necrosis caused by cytomegalovirus. METHODS:A diagnostic vitrectomy was performed on a patient with non-Hodgkin lymphoma who presented with a bilateral, rapidly progressing necrotizing retinitis and uveitis. RESULTS:Immunohistochemical studies and polymerase chain r...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00250-5
更新日期:1999-01-01 00:00:00