Abstract：
:We studied the behavior of intraocular pressure in glaucoma suspects randomly selected to receive either topical timolol or no treatment over the course of a long-term prospective follow-up study. All patients who after six years of follow-up showed no localized field defects or disk changes, or whose pressures were not dangerously increased (24 treated and 22 untreated patients), were included in the present study. Overall, the two groups showed an increase in pressure followed by a gentle leveling off and a decrease toward the end of the follow-up period. The pressure-time curves of the two groups were parallel and vertically separated by 4.94 mm Hg. When pressure-time relationships were determined in individual patients, the categorical group differences were not statistically significant. Our results suggest that most glaucoma suspects did not exhibit a random time-course of intraocular pressure and that the effect of treatment was simply to lower the pressure-time curve of the treated group by a fixed level throughout the six-year follow-up period.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Chauhan BC,Drance SM,Douglas GRdoi
10.1016/0002-9394(89)90490-xsubject
Has Abstractpub_date
1989-05-15 00:00:00pages
471-5issue
5eissn
0002-9394issn
1879-1891pii
0002-9394(89)90490-Xjournal_volume
107pub_type
临床试验,杂志文章,随机对照试验abstract：:A patient had corneal infection with Staphylococcus aureus after keratoplasty from tissue preserved in McCarey-Kaufman medium. The small, successfully treated corneal infection was from the same organism cultured from the tissue culture medium at the time of transplantation. Possible sources of donor-tissue contaminat...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90755-4
更新日期：1979-07-01 00:00:00
abstract：PURPOSE:To compare the visual outcome after foveal translocation by scleral shortening and that after 360 degrees retinotomy with extraocular muscle surgery in a patient with bilateral myopic neovascular maculopathy. METHODS:Case report. RESULTS:A 52-year-old woman with bilateral myopic neovascular maculopathy underw...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00582-1
更新日期：2000-10-01 00:00:00
abstract：:We treated 23 consecutive cases of giant retinal tears with inverted retinal flaps. We used pars plana vitrectomy together with an intravitreal bubble to unfold the posterior retinal flap, combined with cryotherapy to cause a chorioretinal adhesion and a broad scleral buckle. The vitrectomy was done after applying cry...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90132-6
更新日期：1984-10-15 00:00:00
abstract：:A 46-year-old woman had a hemangioma of the zygoma, which was excised flush with the normal bony contour. To the best of our knowledge, this is the second such case reported. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74865-2
更新日期：1980-08-01 00:00:00
abstract：PURPOSE:To evaluate the anatomic and visual outcomes in patients with initially closed macular holes after vitreoretinal surgery and with 1 to 7 years of follow-up. DESIGN:Retrospective, noncomparative, consecutive case series. METHODS:Eighty-seven consecutive eyes of 79 patients with previous closure of the macular ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.11.006
更新日期：2011-05-01 00:00:00
abstract：PURPOSE:To report a case of unilateral blindness after ipsilateral prophylactic transcranial optic canal decompression for fibrous dysplasia. METHODS:Case report. A 37-year-old woman with fibrous dysplasia underwent a prophylactic left optic canal decompression. Preoperatively, the left eye had a visual acuity of 20/2...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00118-4
更新日期：1998-09-01 00:00:00
abstract：PURPOSE:To determine whether clinically isolated anterior segment recurrence is associated with concomitant subclinical choroidal inflammation in Vogt-Koyanagi-Harada (VKH) disease. DESIGN:Interventional, retrospective case series. METHODS:Nine patients with recurrent VKH disease who satisfied the following criteria:...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.10.012
更新日期：2008-03-01 00:00:00
abstract：PURPOSE:To report the occurrences of early rapid increases in intraocular (IOP) after intravitreal glucocorticoid injection. DESIGN:Observational case series. METHODS:We retrospectively reviewed the records of three patients seen and treated at Duke Eye Center. RESULTS:In all three cases, a significant rise in IOP o...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.03.001
更新日期：2004-08-01 00:00:00
abstract：:Lamellar keratoplasty was done in 18 eyes with keratoconus in an attempt to obtain a more satisfactory postoperative refractive error than that after penetrating keratoplasty. The refractive error after lamellar keratoplasty was better than that after 7.5-mm penetrating keratoplasties, but the vision was not as good. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(77)90563-3
更新日期：1977-04-01 00:00:00
abstract：PURPOSE:To show that extending Doppler imaging into the high-frequency domain could allow detection and characterization of blood flow in small arterioles and capillaries. METHODS:A 40-MHz continuous wave Doppler system and a 60-MHz pulsed-wave Doppler system were constructed, tested, and used to examine the ciliary b...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00122-6
更新日期：1998-10-01 00:00:00
abstract：PURPOSE:To describe the ultrasound features seen in orbital hydatid disease, which may confirm the diagnosis preoperatively. DESIGN:Interventional case series. METHODS:Nine patients of orbital hydatid cyst were evaluated preoperatively with ultrasound and computed tomography scans. The diagnostic features seen on ult...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)02083-4
更新日期：2003-04-01 00:00:00
abstract：PURPOSE:To describe the effect of internal limiting membrane peeling in chronic recalcitrant pseudophakic cystoid macular edema. DESIGN:Two interventional case reports. METHODS:Two consecutive patients with chronic pseudophakic cystoid macular edema of 11-22 months duration, after uncomplicated cataract surgery, unre...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01402-7
更新日期：2002-04-01 00:00:00
abstract：:There is no single method of perimetric examination which is applicable to all types of visual field defects. Perimetry is a subjective psychophysical sensory examination. It is not an exact science unless one includes the objective measurement of visual evoked response in the optic cortex. Until such a method becomes...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90527-9
更新日期：1975-09-01 00:00:00
abstract：:We studied the use of human retinal pigment epithelial cells cultured on a collagen support as a potential transplantation therapy to replace diseased or damaged retinal pigment epithelium. Using a transvitreal approach, we transplanted human retinal pigment epithelial cells attached to either a sheet of noncross-link...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73079-x
更新日期：1994-02-15 00:00:00
abstract：PURPOSE:To evaluate total plasma homocysteine (tHcy) levels in patients diagnosed with primary open-angle glaucoma (POAG) and normal subjects. DESIGN:Case-control study. METHODS:This study involved 55 POAG patients, 16 patients with secondary open-angle glaucoma or angle-closure glaucoma (non-POAG group), and 39 cont...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2003.09.041
更新日期：2004-03-01 00:00:00
abstract：PURPOSE:To describe ocular motility in patients having genetically characterized dominant cerebellar ataxia. DESIGN:Observational case series. METHOD:Nine ataxic adults having the following molecular genetic diagnoses underwent ophthalmic examination and ocular motility recordings: four with spinocerebellar ataxia ty...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01328-4
更新日期：2002-05-01 00:00:00
abstract：PURPOSE:To evaluate low- vs high-dose plaque brachytherapy for juxtapapillary choroidal melanoma. DESIGN:Retrospective interventional case series. METHODS:Setting: Single institution. STUDY POPULATION:Forty-seven patients with juxtapapillary choroidal melanoma. INTERVENTION:Iodine-125 plaque brachytherapy. Eyes wer...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.11.008
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:To investigate sclerochoroidal calcification in a patient with Gitelman syndrome. METHOD:Case report. Bilateral fundus abnormalities observed in a 58-year-old woman were documented with fluorescein angiography and tomodensitometry. RESULTS:Symmetric yellow-white subretinal lesions were observed in the superot...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00277-9
更新日期：1999-12-01 00:00:00
abstract：:We have developed a new model of retinal neovascularization in the rabbit. After intravitreal autotransplantation of 250,000 tissue-cultured skin fibroblasts, we observed strand formation in the midvitreous cavity. These strands grew toward the vascularized part of the retina and attached to it. Once the attachment wa...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75913-6
更新日期：1981-07-01 00:00:00
abstract：:The prevalence of diabetic retinopathy was lower in a rural diabetic population when compared to the prevalence of diabetic retinopathy in medical center clinic populations. Adult-onset (Type II) diabetics were at greater risk for developing diabetic retinopathy shortly after diagnosis than newly diagnosed cases of ju...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90502-6
更新日期：1984-06-01 00:00:00
abstract：PURPOSE:To investigate the prevalence of and risk factors associated with dry eye syndrome (DES) in South Korea. DESIGN:Cross-sectional study. METHODS:In 2010 and 2011, 11,666 subjects, ranging in age from 19 to 95, were randomly selected as nationally representative participants in the Korea National Health and Nutr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.08.021
更新日期：2014-12-01 00:00:00
abstract：PURPOSE:To estimate the cumulative probability of Nd:YAG laser posterior capsulotomy after cataract extraction in a geographically defined population. METHODS:Rochester Epidemiology Project databases were used to identify retrospectively all Nd:YAG laser posterior capsulotomies performed on Olmsted County, Minnesota, ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00795-9
更新日期：2001-02-01 00:00:00
abstract：:We used wide-field color specular microscopy of the human corneal surface to study the morphologic changes that occur under extended-wear contact lenses. There was a shift in the frequency distribution of surface cells by size to larger cells, suggesting a prolonged residence time on the ocular surface. Other abnormal...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90818-4
更新日期：1986-03-15 00:00:00
abstract：:We reviewed the charts of 29 patients with large subretinal hemorrhages involving the center of the fovea to evaluate factors that might be prognostic of visual outcome. The average final visual acuity was 20/480 with a mean follow-up of three years. Patients with thick hemorrhages (causing an obvious elevation of the...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75575-8
更新日期：1990-01-15 00:00:00
abstract：PURPOSE:To compare three phacoemulsification machines for measurement accuracy and postocclusion surge (POS) in human cadaver eyes. DESIGN:In vitro comparisons of machine accuracy and POS. METHODS:Tip vacuum and flow were compared with machine indicated vacuum and flow. All machines were placed in two human cadaver e...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.01.024
更新日期：2008-06-01 00:00:00
abstract：PURPOSE:To present a case of cancer-associated retinopathy (CAR) in a patient with small cell carcinoma of the lung and antiretinal antibodies who experienced visual symptoms before diagnosis of cancer. DESIGN:Case report. METHODS:A 61-year-old man with a sudden loss of vision and photophobia was referred to the opht...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.10.044
更新日期：2005-04-01 00:00:00
abstract：PURPOSE:To identify clinical and microbiologic factors influencing the prevalence and visual outcomes in endophthalmitis after deadly-weapon-related open-globe injuries. METHODS:In a retrospective study of 228 eyes of 212 patients with deadly-weapon-related open-globe injuries, clinical and microbiologic factors influ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(01)01320-4
更新日期：2002-01-01 00:00:00
abstract：PURPOSE:To examine whether indocyanine green (ICG) dye induces apoptosis in human retinal pigment epithelial (RPE) cells. DESIGN:Laboratory investigation. METHODS:Pure cultures of human RPE cells were isolated. Retinal pigment epithelial cells were incubated with different concentrations of ICG dye (1 mg/ml, 5 mg/ml,...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2003.11.016
更新日期：2004-05-01 00:00:00
abstract：PURPOSE:To determine the repeatability of automated retinal and choroidal thickness measurements with swept-source optical coherence tomography (SS OCT) and the frequency and type of scan artifacts. DESIGN:Prospective evaluation of new diagnostic technology. METHODS:Thirty healthy subjects were recruited prospectivel...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.02.008
更新日期：2014-05-01 00:00:00
abstract：PURPOSE:To assess the role of muscular degeneration, we evaluated the correlation between ptosis severity and levator muscle function. DESIGN:Retrospective cohort study. METHODS:The medical records of 136 patients (53 men and 83 women; mean age, 67 years) with acquired blepharoptosis were reviewed for levator functio...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.02.002
更新日期：2008-06-01 00:00:00
