Abstract:
:Tissue for pathologic examination was obtained from three cases of acute retinal necrosis syndrome. Virus particles belonging to the herpesvirus family were demonstrated in retinal biopsies from two patients, one of whom was immunosuppressed. Despite removal of large biopsy specimens, the retina has remained attached for 20 months postoperatively in one case and for three months in the other. In a third patient with acquired immune deficiency syndrome, the clinical course and postmortem immunopathology were suggestive of a herpes simplex virus infection, initially affecting the retina and subsequently the optic nerves, chiasm, tracts, and central nervous system. These cases illustrate that the virus associated with the acute retinal necrosis syndrome is easily demonstrable using vitrectomy and endoretinal biopsy in the acute phase of the disease, but may be difficult to demonstrate in chronically detached atrophic retinas.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Freeman WR,Thomas EL,Rao NA,Pepose JS,Trousdale MD,Howes EL,Nadel AJ,Mines JA,Bowe Bdoi
10.1016/0002-9394(86)90396-xsubject
Has Abstractpub_date
1986-12-15 00:00:00pages
701-9issue
6eissn
0002-9394issn
1879-1891pii
0002-9394(86)90396-Xjournal_volume
102pub_type
杂志文章abstract::Two siblings had atrophic maculopathy associated with hereditary ataxia clinically defined as an olivopontocerebellar degeneration. The macular changes were suggestive of an early bull's-eye maculopathy in one case and of a late atrophic stage of bull's-eye maculopathy in the other. This suggests that concentric annul...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75125-6
更新日期:1980-11-01 00:00:00
abstract::Subretinal neovascular membranes cause late visual loss and are important determinants of final visual acuity in patients with Vogt-Koyanagi-Harada syndrome. The purpose of this study was to determine the prevalence and risk factors associated with the development of subretinal neovascular membranes in Vogt-Koyanagi-H...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71280-2
更新日期:1993-08-15 00:00:00
abstract:PURPOSE:To delineate the clinical features, course, complications, and associated systemic diseases in patients with HLA-B27-associated uveitis. METHODS:We reviewed the records of 148 patients with HLA-B27-associated uveitis from two large uveitis practices. RESULTS:There were 127 (86%) white and 21 (14%) nonwhite pa...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/s0002-9394(14)70533-1
更新日期:1996-01-01 00:00:00
abstract::Cataract operations may be recommended when retinal disease is suspected but cannot be adequately diagnosed or treated because of lens opacity. We evaluated the outcome of cataract operations performed under those circumstances. We reviewed the records of 119 patients who were examined at the Wilmer Retinal Vascular C...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75793-9
更新日期:1994-10-15 00:00:00
abstract:PURPOSE:To report a patient with persistent subepithelial corneal opacities 18 months after adenoviral keratoconjunctivitis who underwent photorefractive keratectomy for the correction of myopia. METHODS:Case report, review of medical literature, and slit-lamp photography. RESULTS:The patient underwent photorefractiv...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00224-4
更新日期:1998-12-01 00:00:00
abstract::Six patients (all male, five homosexual and one bisexual, 23 to 48 years old) with the acquired immune deficiency syndrome (AIDS) who had cytomegalovirus retinitis were treated with a new antiviral drug as a part of a prospective open-labeled trial for serious cytomegalovirus infections. The drug, 9-[2-hydroxy-1-(hydr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(86)90638-0
更新日期:1986-04-15 00:00:00
abstract::The extent of visual function loss from nuclear cataractous change can be estimated by observing the extinction of blue light compared to white light as a function of sagittal lens depth in standard slit lamps. Apparent extinction (loss of transmissivity) of 50% or more of the depth of the lens in blue light of maxima...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(81)90057-x
更新日期:1981-05-01 00:00:00
abstract::The files of 45 human immunodeficiency virus-infected patients with ocular toxoplasmosis were reviewed, with a median follow-up of eight months. The condition was unilateral in 37 of the 45 patients (82%) and was bilateral in eight (18%). Inflammation of the anterior chamber and the vitreous was present in 32 of 53 ey...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73975-3
更新日期:1992-08-15 00:00:00
abstract::Benign lateral rectus palsy developed in two adults, a 62-year-old man and a 56-year-old woman. Both were hospitalized because of headache and diplopia. Extensive laboratory and neurologic testing showed no abnormalities except leukopenia (the white blood cell count was 2,600 cells/mm3 in one patient and 3,100 cells/m...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1982-10-01 00:00:00
abstract::A central retinal artery occlusion occurred in the left eye of a 25-year-old woman with migraine and bilateral intrapapillary drusen. An extensive investigation failed to establish the presence of any systemic disease or vasculopathy. Eight years later she had a central retinal artery occlusion in her right eye. Optic...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(89)90305-x
更新日期:1989-03-15 00:00:00
abstract::A patient had corneal infection with Staphylococcus aureus after keratoplasty from tissue preserved in McCarey-Kaufman medium. The small, successfully treated corneal infection was from the same organism cultured from the tissue culture medium at the time of transplantation. Possible sources of donor-tissue contaminat...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90755-4
更新日期:1979-07-01 00:00:00
abstract::After penetrating keratoplasty, visual rehabilitation can be slow and is largely a function of corneal surface configuration. Computerized topographic analysis allows the detailed study of corneal surface factors that determine the optical function of the graft. We performed a prospective, longitudinal study of eight ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73925-x
更新日期:1993-02-15 00:00:00
abstract::The effect of rapid freezing and thawing was tested in vitro on 100 human hard nuclear cataracts before ultrasonic emulsification. After phacocryolysis the interspace between lens fibers increased, and the normally closely packed fibers appeared to loosen. This seemed to soften the hard cataract, thereby facilitating ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(77)90906-0
更新日期:1977-06-01 00:00:00
abstract:PURPOSE:To determine the morphologic changes in human corneas over time following radiofrequency-based conductive keratoplasty (CK) treatment. DESIGN:Prospective, observational case series. METHODS:In a single-center study six human corneas of six patients with localized peripheral keratoconus underwent CK treatment ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.06.027
更新日期:2005-12-01 00:00:00
abstract::A prospective study of 78 eyes with idiopathic preretinal macular gliosis disclosed that 74 of the 78 (95%) had posterior vitreous detachments at the time of the initial examination. A second prospective study of 34 eyes with acute posterior vitreous detachment showed preretinal macular gliosis in three eyes (9%) init...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(86)90144-3
更新日期:1986-08-15 00:00:00
abstract:PURPOSE:To investigate the relationship between intraretinal macular hemorrhage and visual acuity outcomes in eyes with central retinal vein occlusion or hemiretinal vein occlusion managed with aflibercept, bevacizumab, or observation. DESIGN:Retrospective analysis of data from 2 randomized clinical trials. METHODS:A...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.08.030
更新日期:2020-08-20 00:00:00
abstract:PURPOSE:To examine the relationship between hypertension and lens opacities, and the use of antihypertensive agents. METHODS:A total of 4,926 adults, 43 to 84 years of age, living in Beaver Dam, Wisconsin, at the time of a private census, were invited to participate in a study that included a medical interview and an ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70223-5
更新日期:1995-05-01 00:00:00
abstract:PURPOSE:To describe the clinical and genetic characteristics of three Japanese families with autosomal dominant retinitis pigmentosa (ADRP) associated with mutations in the PRPF31 gene. DESIGN:Case reports and results of DNA analysis. METHODS:Mutational screening of the PRPF31 gene was performed on 96 unrelated patie...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.02.050
更新日期:2005-09-01 00:00:00
abstract::Eight patients with severe traumatic hyphemas underwent clot evacuation with vitrectomy instrumentation. The patients were followed up for periods of one to four years. No significant intraoperative complications were noted, but one eye developed a postoperative flat anterior chamber and another developed multiple sta...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(79)90574-9
更新日期:1979-11-01 00:00:00
abstract:PURPOSE:To describe the long-term surgical course of patients with open globe injury. DESIGN:Retrospective case series. METHODS:Patients with open globe injuries (848 in total) treated surgically at the Massachusetts Eye and Ear Infirmary between 2000 and 2009 were retrospectively reviewed. Data from presentation, in...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2011.10.013
更新日期:2012-05-01 00:00:00
abstract::The flat, circumscribed, and hyperpigmented lesion of the retinal pigment epithelium (RPE) without clinically apparent involvement of the overlying retina, designated as congenital hypertrophy, was found to be associated with corresponding scotomas in the visual field. The depth of the scotoma increased with the age o...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90069-0
更新日期:1975-02-01 00:00:00
abstract:PURPOSE:To report the sensitivity and specificity of B-scan ultrasonography to detect macular thickening. DESIGN:Observational case series. METHODS:Seventy-seven eyes of 40 consecutive patients (age range, 7-80 years) in a retinal specialty practice were examined. A single masked ultrasound operator performed B-scan ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)02273-0
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:To assess the results of iris suture fixation of subluxated intraocular lenses. DESIGN:Retrospective study. METHODS:This was a nonrandomized chart review of eyes with subluxated intraocular lenses that underwent iris suture fixation at an academic institutional care center. Seventy-two eyes of 67 consecutive ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2014.11.009
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:To look for associations of preoperative A-scan ultrasound ocular dimensions with complications during phacoemulsification in eyes with pseudoexfoliation. METHODS:A total of 174 eyes with pseudoexfoliation of 135 patients undergoing planned cataract surgery were included in a prognostic study based on the revi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00365-7
更新日期:2000-03-01 00:00:00
abstract::Beta-aminopropionitrile, an inhibitor of collagen cross-linking, effectively limited the degree of posttraumatic vitreous proliferation in rabbits three weeks after double perforating injury. Light microscopic examination of the sites of perforating injury after five weeks showed minimal intravitreal fibrous prolifera...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(83)90337-9
更新日期:1983-01-01 00:00:00
abstract:PURPOSE:To compare the accuracy of toric intraocular lens (IOL) alignment and visual outcomes using femtosecond laser-assisted capsulotomy marking (CM) versus conventional slit lamp-assisted manual marking (MM). DESIGN:Prospective cohort study. METHODS:A total of 57 patients who required cataract surgery and toric IO...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.08.041
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To compare the extent of mucosal margins remaining unsutured at the end of external dacryocystorhinostomy (DCR) using single or double flap techniques and to evaluate the influence on outcome. DESIGN:Prospective, consecutive case series. METHODS:The number and length of mucosal margins remaining unsutured at ...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ajo.2004.06.032
更新日期:2004-11-01 00:00:00
abstract::Two of six patients (four women and two men ranging in age from 51 to 90 years) with bilateral senile iridoschisis also had secondary unilateral narrow angle or angle-closure glaucoma. All six patients had splitting of the iris stroma inferiorly. Histopathologic studies disclosed marked iris stromal atrophy without ev...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(83)90335-5
更新日期:1983-01-01 00:00:00
abstract:PURPOSE:To determine factors of uveal malignant melanoma that would help to predict prognosis in Japanese patients. METHODS:From 1969 to 1994, 23 eyes with uveal malignant melanoma were enucleated from 23 Japanese patients, and 16 of these patients were studied. In the 16 patients, enucleated eyes were evaluated for t...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70275-2
更新日期:1996-03-01 00:00:00
abstract:PURPOSE:To increase the vaccination rate and identify barriers to administration of the vaccine against herpes zoster by having ophthalmologists screen and provide the vaccine. DESIGN:Prospective interventional cohort study. METHODS: SETTING:Academic City Hospital, Bellevue Hospital. PARTICIPANTS:A total of 100 eli...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ajo.2012.11.022
更新日期:2013-05-01 00:00:00