Abstract：
:Beta-aminopropionitrile, an inhibitor of collagen cross-linking, effectively limited the degree of posttraumatic vitreous proliferation in rabbits three weeks after double perforating injury. Light microscopic examination of the sites of perforating injury after five weeks showed minimal intravitreal fibrous proliferation in treated animals. Electron micrographs of the cicatricial vitreous collagen showed fragmentation of collagen into smaller fibrils and disintegration into amorphous areas. Inhibition of collagen cross-linking may undermine the strength of the vitreous scaffold by making vitreous and cicatricial collagen more sensitive to tissue collagenases produced during inflammation. The failure of fibrovascular membranes to grow into the vitreous may be a secondary effect of weakened vitreous support.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Moorhead LCdoi
10.1016/0002-9394(83)90337-9subject
Has Abstractpub_date
1983-01-01 00:00:00pages
97-109issue
1eissn
0002-9394issn
1879-1891pii
0002-9394(83)90337-9journal_volume
95pub_type
杂志文章abstract：:Conjunctivodacryocystorhinostomy with a Jones tube is an accepted procedure for the treatment of epiphora resulting from obstructed canaliculi. Because of our clinical impression that a high rate of functional success after surgery is associated with a lower rate of patient satisfaction, we analyzed the results and pa...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70070-4
更新日期：1994-05-15 00:00:00
abstract：PURPOSE:To investigate the prevalence of and risk factors associated with dry eye syndrome (DES) in South Korea. DESIGN:Cross-sectional study. METHODS:In 2010 and 2011, 11,666 subjects, ranging in age from 19 to 95, were randomly selected as nationally representative participants in the Korea National Health and Nutr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.08.021
更新日期：2014-12-01 00:00:00
abstract：PURPOSE:To classify and describe clinically meaningful classes of color vision defects using pretreatment Farnsworth-Munsell 100-hue results from the Early Treatment Diabetic Retinopathy Study (ETDRS) patients using standard statistical techniques. DESIGN:The ETDRS was a randomized trial investigating retinal photocoa...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ajo.2004.02.009
更新日期：2004-07-01 00:00:00
abstract：:Between 1976 and 1982, we examined 13 patients with clinical and radiographic findings consistent with optic nerve sheath meningioma. All patients had visual loss, evidence of optic nerve dysfunction, centrocecal visual field defects, and echographic and computed tomographic evidence of optic nerve or sheath enlargeme...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(85)90506-9
更新日期：1985-09-15 00:00:00
abstract：PURPOSE:To apply in vivo corneal confocal microscopy (IVCM) to study the pathogenesis of keratitis (keratoendotheliitis) fugax hereditaria, an autosomal dominant cryopyrin-associated periodic keratitis, associated with the c.61G>C pathogenic variant in the NLRP3 gene, in its acute and chronic phase, and to report histo...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.02.002
更新日期：2020-05-01 00:00:00
abstract：PURPOSE:To investigate the effect of nocturnal blood pressure (BP) dips on the occurrence of optic disc hemorrhage (ODH) in normal-tension glaucoma (NTG) patients and determine whether ODH is associated with greater likelihood of visual field progression (VFP). DESIGN:Prospective case-control study. METHODS:This stud...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.01.002
更新日期：2017-04-01 00:00:00
abstract：:We compared the intraocular pressure-decreasing effect of timolol maleate alone, acetazolamide alone, and combined timolol and acetazolamide therapy in nine patients with bilateral chronic open-angle glaucoma. Timolol decreased intraocular pressure at least as effectively as acetazolamide. The two medications together...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75631-4
更新日期：1981-12-01 00:00:00
abstract：PURPOSE:To evaluate long-term outcomes after Ahmed valve implantation in patients with glaucoma when using adjunctive intraoperative mitomycin C (MMC) and postoperative 5-fluorouracil (5-FU). DESIGN:Retrospective, interventional, consecutive case series. METHODS:A consecutive series of eyes undergoing Ahmed valve imp...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.04.008
更新日期：2008-08-01 00:00:00
abstract：PURPOSE:Wavelength dependence of diffractive intraocular lenses (IOLs) was recognized in vitro but not yet assessed in vivo. By examining pseudophakic patients who had extended-depth-of-focus diffractive implants, this spectral effect on their vision was measured clinically and the lens was tested in vitro. DESIGN:Cro...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2019.07.001
更新日期：2019-12-01 00:00:00
abstract：PURPOSE:To determine the prevalence of artifacts on segmented spectral-domain optical coherence tomography (SDOCT) images and assess their impact on the interpretation of glaucomatous progression in the retinal nerve fiber layer (RNFL) profile and macular thickness map. DESIGN:Retrospective reliability analysis. METH...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.08.018
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:Age-related maculopathy (ARM) and cognitive impairment are both neurodegenerative disorders associated with aging and have been hypothesized to share common pathogenic pathways. We describe the association between cognitive function and ARM in middle-aged persons. DESIGN:Population-based, cross-sectional study...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01672-0
更新日期：2002-12-01 00:00:00
abstract：PURPOSE:To determine provider compliance with hydroxychloroquine screening following the revised recommendations published in 2011 by the American Academy of Ophthalmology. DESIGN:Evaluation of adherence to a screening protocol. METHODS:Subjects were identified with hydroxychloroquine as a medication by electronic qu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2015.06.009
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:To characterize spontaneous dislocation of the fluocinolone acetonide sustained release implant (Retisert; Bausch & Lomb) drug pellet from its strut. DESIGN:Retrospective, observational case series. METHODS:The medical records of 224 patients in whom 407 fluocinolone acetonide implants were placed by either o...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2015.01.031
更新日期：2015-05-01 00:00:00
abstract：:I fitted nine aphakic patients who had undergone penetrating keratoplasty with extended-wear hydrophilic contact lenses (55% to 80% water content). All patients had edematous host corneas. Eight of nine developed vascularization of the graft after two to 30 weeks of contact lens wear. One patient developed a presumed ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74912-8
更新日期：1980-09-01 00:00:00
abstract：:Induced prolonged complementary chromatopsia in four subjects (two men, 26 and 34 years old, and two women, 34 and 45 years old) was documented by abnormal responses to pseudoisochromatic color plates 30 minutes after cessation of monochrome video display terminal use. This phenomenon was unrelated to preexisting colo...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(84)90694-9
更新日期：1984-12-15 00:00:00
abstract：:We performed 115 scleral-buckling procedures for primary rhegmatogenous retinal detachments in which the argon endolaser drained subretinal fluid. The laser was set at 0.80 to 1.25 W and 0.5 second; the endolaser probe was held adjacent to, but not touching, the choroid. The procedure was successful in 112 of 115 (97....
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)73643-8
更新日期：1993-06-15 00:00:00
abstract：:A 70-year-old man, a 59-year-old woman, and a 57-year-old woman underwent pars plana vitrectomy. In all three cases, cataracts developed in the eyes that had been operated on. During cataract extraction, which included massage of the globe after retrobulbar anesthesia and a conventional ab externo incision, loss of le...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(78)90179-4
更新日期：1978-11-01 00:00:00
abstract：PURPOSE:To provide a systematic classification of fundus autofluorescence (FAF) patterns in patients affected by Best vitelliform macular dystrophy. DESIGN:Cross-sectional prospective study. METHODS:Patients affected by Best vitelliform macular dystrophy at different stages of the disease were prospectively enrolled ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.07.026
更新日期：2014-11-01 00:00:00
abstract：:Graft edema developed after removal of continuous monofilament sutures in six eyes of six patients in whom no wound dehiscence occurred. All sutures were removed at least one year after penetrating keratoplasty, and graft edema was noted one day after suture removal. In all cases, partial or total resolution of graft ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90461-6
更新日期：1979-08-01 00:00:00
abstract：PURPOSE:To investigate the effect of shorter axial length on the laser spot size and laser energy during photodynamic therapy (PDT) in monkeys. DESIGN:Experimental study with four rhesus monkeys. METHODS:PDT was performed on the normal retina of monkeys whose ocular axial lengths are shorter (19.55 to 20.25 mm) than ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.08.016
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:To develop a near-real-time data warehouse (DW) in an academic ophthalmologic center to gain scientific use of increasing digital data from electronic medical records (EMR) and diagnostic devices. DESIGN:Database development. METHODS:Specific macular clinic user interfaces within the institutional hospital in...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.03.026
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:To compare the results of combined trabeculectomy and phacoemulsification surgery with intraocular lens implant by means of a one-site vs a two-site approach. METHODS:Glaucomatous patients with a coexisting cataract were randomly assigned to undergo either a one-site or two-site combined procedure. One-site su...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9394(99)80143-3
更新日期：1998-03-01 00:00:00
abstract：PURPOSE:To investigate the ocular manifestations of patients with severe acute respiratory syndrome (SARS) and to monitor the possible ocular complications arising from the treatment regimen with high-dose systemic corticosteroid drugs. DESIGN:Prospective, observational cohort case series. METHODS:Ninety eyes from 45...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2003.09.060
更新日期：2004-04-01 00:00:00
abstract：PURPOSE:To measure the changes in optic disk morphology after unilateral disk hemorrhage and to compare the changes between eyes. DESIGN:Observational case series. METHODS:Ten glaucoma patients who had a unilateral disk hemorrhage were enrolled. The baseline measurements obtained by Heidelberg Retina Tomograph (HRT) ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01791-9
更新日期：2002-12-01 00:00:00
abstract：PURPOSE:To characterize features of glaucoma associated with a TANK binding kinase 1 (TBK1) gene duplication, which is among the most common molecularly defined causes of normal tension glaucoma (NTG). DESIGN:Retrospective observational case series. METHODS:We conducted a retrospective case series, by reviewing medic...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.01.017
更新日期：2020-06-01 00:00:00
abstract：:Eight patients with severe traumatic hyphemas underwent clot evacuation with vitrectomy instrumentation. The patients were followed up for periods of one to four years. No significant intraoperative complications were noted, but one eye developed a postoperative flat anterior chamber and another developed multiple sta...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90574-9
更新日期：1979-11-01 00:00:00
abstract：:We conducted a retrospective study of 45 eyes of 45 patients with chronic open-angle glaucoma to evaluate the rate of progression of scotomas. "Scotoma mass" was calculated and regressed on time to obtain the rate of visual field change. Twenty-two eyes (49%) showed a linear type of progression, nine (20%) showed a cu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(86)90457-5
更新日期：1986-01-15 00:00:00
abstract：PURPOSE:To assess the role of muscular degeneration, we evaluated the correlation between ptosis severity and levator muscle function. DESIGN:Retrospective cohort study. METHODS:The medical records of 136 patients (53 men and 83 women; mean age, 67 years) with acquired blepharoptosis were reviewed for levator functio...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.02.002
更新日期：2008-06-01 00:00:00
abstract：PURPOSE:To study the results of phacoemulsification cataract surgery complicated by anterior capsule tear. DESIGN:Retrospective interventional controlled case series. METHODS:Consecutive series of eyes suffering intraoperative anterior capsule tear and others with uneventful cataract surgery at Moorfields Eye Hospita...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.11.027
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:To evaluate the long-term results of 2-muscle surgery in children with primary large-angle exotropia, comparing 10 mm bilateral lateral rectus recession (BLR) with unilateral lateral rectus recession-medial rectus resection (recess/resect). DESIGN:Retrospective case series. METHODS:Eighty-six children with ex...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2014.02.038
更新日期：2014-06-01 00:00:00
