Abstract:
:We conducted a retrospective study of 45 eyes of 45 patients with chronic open-angle glaucoma to evaluate the rate of progression of scotomas. "Scotoma mass" was calculated and regressed on time to obtain the rate of visual field change. Twenty-two eyes (49%) showed a linear type of progression, nine (20%) showed a curvilinear progression, three (7%) showed episodic progression, and 11 (24%) showed no significant progression. The mean scotoma mass was significantly lower in the curvilinear group than in the linear group.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Mikelberg FS,Schulzer M,Drance SM,Lau Wdoi
10.1016/0002-9394(86)90457-5subject
Has Abstractpub_date
1986-01-15 00:00:00pages
1-6issue
1eissn
0002-9394issn
1879-1891pii
0002-9394(86)90457-5journal_volume
101pub_type
杂志文章abstract:PURPOSE:To report ocular findings in the mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS syndrome) in a family with the A to G 3243 mitochondrial (mt) DNA point mutation. METHODS:Case reports. Ocular findings are described from four family members with the MELAS associated A to G 3243...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00057-4
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:To investigate the characteristics, mergers, and risk factors of different types of myopic maculopathy (MM) in a highly myopic population. DESIGN:Population-based, cross-sectional study. METHODS:A total of 1086 eyes (762 patients) were enrolled. Each participant underwent detailed ocular examinations. Combini...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.07.010
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To investigate in open-angle glaucoma the focal macular photopic negative response and spectral-domain optical coherence tomography measurements of retinal thicknesses in the superior and inferior macula. DESIGN:Comparative case series. METHODS:We studied 63 eyes of 63 patients with open-angle glaucoma and 41...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2010.09.018
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:To compare the intraocular pressure)-lowering effect and side effects of latanoprost 0.005% once daily with unoprostone 0.12% twice daily. METHODS:Sixty patients with primary open-angle glaucoma or ocular hypertension were randomized to receive either latanoprost once daily in the evening and placebo once dail...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0002-9394(00)00943-0
更新日期:2001-05-01 00:00:00
abstract:PURPOSE:To present a case of congenital toxoplasmosis in a newborn whose mother had a 20-year history of a chorioretinal macular scar and positive serology for toxoplasmosis. DESIGN/METHODS:Case report. SETTING/RESULTS: A 38-year-old woman who had been treated for ocular toxoplasmosis 20 years earlier delivered a newb...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00191-0
更新日期:2003-08-01 00:00:00
abstract:PURPOSE:Macular imaging with optical coherence tomography (OCT) measures the most critical retinal ganglion cells (RGCs) in the human eye. The goal of this perspective is to review the challenges to detection of glaucoma progression with macular OCT imaging and propose ways to enhance its performance. DESIGN:Perspecti...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.09.026
更新日期:2020-09-18 00:00:00
abstract:PURPOSE:To evaluate corneal biomechanical properties across the glaucoma spectrum and study the relationship between these measurements and intraocular pressure measured by Goldmann applanation tonometry (GAT-IOP) and central corneal thickness (CCT). DESIGN:Prospective cross-sectional study. METHODS: SETTING:Tertiar...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2011.10.032
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:To assess the association between smoking, alcohol intake, estrogen use, and both early age-related macular degeneration (AMD) (soft indistinct drusen, retinal pigment abnormalities) and advanced AMD (exudative AMD, geographic atrophy) in the Latino community. DESIGN:Population-based, cross-sectional study. M...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.08.024
更新日期:2006-01-01 00:00:00
abstract::In an 8-year-old girl with asymptomatic proptosis, computed tomographic scans showed a large medial orbital mass that contoured the globe anteriorly, bowed the optic nerve laterally, and extended posteriorly to the orbital apex. T1-weighted coronal magnetic resonance images showed the mass to be a diffusely enlarged m...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)77878-x
更新日期:1990-11-15 00:00:00
abstract:PURPOSE:To assess the results of iris suture fixation of subluxated intraocular lenses. DESIGN:Retrospective study. METHODS:This was a nonrandomized chart review of eyes with subluxated intraocular lenses that underwent iris suture fixation at an academic institutional care center. Seventy-two eyes of 67 consecutive ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2014.11.009
更新日期:2015-02-01 00:00:00
abstract::To determine the hereditary pattern of acute anterior uveitis, we examined seven families-one family with four cases, one family with three cases, and four families with two cases of acute anterior uveitis. A total of 16 patients with uveitis and 28 relatives underwent ocular examinations and serologic determination o...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(81)90003-9
更新日期:1981-06-01 00:00:00
abstract::Clinic patients and students were given several regular drops of commercial 10% phenylephrine HCl, and 1.0% cyclopentolate HCl or 1.0% tropicamide HCl. The drops were given three times at five-minute intervals. Mydriasis and cycloplegia were determined and compared with the results obtained by using one of the followi...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-9394(78)90129-0
更新日期:1978-12-01 00:00:00
abstract::To determine current practices in the management of ocular toxoplasmosis, 72 of 85 uveitis specialists (85%) in the American Uveitis Society completed a detailed questionnaire. Questions involved the indications for beginning treatment, choice of antiparasitic/antimicrobial agents, and experience with treatment of ocu...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73706-7
更新日期:1991-05-15 00:00:00
abstract:PURPOSE:To report a case of Serratia Marcescens corneal ulcer as a complication of orthokeratology treatment. METHODS:Case report. RESULTS:A 9-year-old male who underwent orthokeratology treatment for 6 months suffered from a corneal ulcer. The refractive state of lesion eye was -5.5D/-1.25D x 180 degrees, and visual...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(01)00931-x
更新日期:2001-08-01 00:00:00
abstract:PURPOSE:To assess the effect of Ahmed glaucoma valve implants on corneal endothelial cell density (ECD) in children with uveitic glaucoma. DESIGN:Cross-sectional study. METHODS:setting: Institutional. patientpopulation: Eighty eyes from 42 patients diagnosed with uveitis before the age of 16. Twenty-eight eyes had an...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2012.09.001
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To determine with electronic monitoring an objective measurement of adherence in two populations of subjects: those using once-daily prostaglandin analogs as sole ocular hypotensive therapy (one-drug group) and those requiring an adjunctive medicine to the prostaglandin analog (two-drug group). DESIGN:Single-s...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2007.06.012
更新日期:2007-10-01 00:00:00
abstract::A 29-year-old white man developed a corneal ulcer following trauma to his left cornea by a piece of wire. Tritirachium roseum, a saprophytic fungus, was cultured from corneal scrapings and demonstrated in the corneal button by histopathologic examination. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90275-5
更新日期:1975-11-01 00:00:00
abstract:PURPOSE:To correlate in vivo imaging to histology in an eye with macular atrophy owing to age-related macular degeneration (AMD; complete retinal pigment epithelium [RPE] and outer retinal atrophy [cRORA]) to evaluate the utility of new optical coherence tomography (OCT) suggested by previous histology. DESIGN:Case st...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2018.06.020
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:To compare 5-year visual acuity and refraction outcome in Descemet stripping automated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PK) for Fuchs endothelial dystrophy (FED) or bullous keratopathy (BK) in Asian eyes. DESIGN:Prospective interventional case series. METHODS:We analyzed 828 cons...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2017.07.014
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:To evaluate a novel Zernike algorithm to differentiate 3-dimensional (3-D) corneal thickness distribution of corneas with keratoconus (KC) from normal corneas. DESIGN:A retrospective development and evaluation of a diagnostic approach. METHODS:Corneal tomography with Scheimpflug imaging was performed in norma...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2015.06.001
更新日期:2015-09-01 00:00:00
abstract::A 26-year-old woman experienced bilateral hearing loss, progressive nasal obstruction, and rhinorrhea. Examination disclosed a retropharyngeal mass. A needle biopsy specimen of the mass showed that it was a chordoma. The patient underwent surgery to remove the mass and received a postoperative course of radioactive co...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)75899-4
更新日期:1981-07-01 00:00:00
abstract:PURPOSE:To apply in vivo corneal confocal microscopy (IVCM) to study the pathogenesis of keratitis (keratoendotheliitis) fugax hereditaria, an autosomal dominant cryopyrin-associated periodic keratitis, associated with the c.61G>C pathogenic variant in the NLRP3 gene, in its acute and chronic phase, and to report histo...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.02.002
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To report successful corticosteroid treatment of optic disc neovascularization associated with uveitis. METHODS:Retrospective review of medical records. RESULTS:Nine patients were identified with chronic uveitis and optic disc neovascularization without clinical or angiographic evidence of retinal ischemia. A...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(00)00598-5
更新日期:2000-12-01 00:00:00
abstract::We studied the in vivo measurements of the autofluorescence of the clear lens in 80 juvenile diabetics and 25 young healthy subjects. When the diabetes was of seven years' duration or more, no overlap with the control subjects was found. The pathologic autofluorescence of the diabetic lens showed a positive correlatio...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1976-04-01 00:00:00
abstract:PURPOSE:To summarize observational studies that focus on the use of glaucoma medications and to identify gaps in knowledge to guide future investigation. DESIGN:Literature study. METHODS:We searched the electronic databases MEDLINE, EMBASE, and PubMed for English language articles published through December 2009 usin...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2010.05.005
更新日期:2010-10-01 00:00:00
abstract::Patients with chronic forms of blepharochalasis often develop eyelid deformities characterized by blepharoptosis and prolapse of the orbital fat and lacrimal gland. Some individuals have an acquired form of blepharophimosis, secondary to the dehiscence of the canthal tendons. In this late stage of the condition, the t...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(85)90009-1
更新日期:1985-04-15 00:00:00
abstract::We studied 1,000 eyes of 500 subjects in an attempt to discover a relationship between lattice and snail track degenerations of the peripheral retina. Because of the clinical similarities between these two degeneration lesions, we suggest that snail track degeneration is either a variant of or an early stage of lattic...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(81)90639-5
更新日期:1981-10-01 00:00:00
abstract::Immunofluorescence, histological, and electron microscopic observations were made on rabbit corneas from animals with experimentally induced stromal keratitis following intracorneal injection with the RE strain of herpes simplex virus. Electron microscopic observations were also made on human corneas obtained from pat...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90057-x
更新日期:1976-12-01 00:00:00
abstract:PURPOSE:To report an unusual, blinding inflicted eye injury in young children. DESIGN:Observational case report. METHODS:Retrospective study in an institutional clinical practice of two families in whom the probands had inferior half keratoconjunctivitis and additional signs of child abuse. RESULTS:Two unrelated inf...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.06.089
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To measure accurately the amount of cyclotorsion. METHODS:A horizontal light beam of the slit lamp is projected on the retina, crossing the fovea. The slit light will normally cross between the middle and lower thirds of the disk. Cyclotorsion of the eye will cause the horizontal slit-light beam to be projecte...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70402-7
更新日期:1996-12-01 00:00:00