Hypertension and lens opacities from the Beaver Dam Eye Study.

Abstract:

PURPOSE:To examine the relationship between hypertension and lens opacities, and the use of antihypertensive agents. METHODS:A total of 4,926 adults, 43 to 84 years of age, living in Beaver Dam, Wisconsin, at the time of a private census, were invited to participate in a study that included a medical interview and an examination that included ocular photography. All study procedures and photographic grading were done according to standard protocols. RESULTS:According to analysis with the Liang-Zeger multiple logistic regression model, people with hypertension were more likely to have posterior subcapsular opacities than people without hypertension (odds ratio, 1.39; 95% confidence interval, 1.05, 1.84). Specific medications for hypertension did not meaningfully affect the risk. Hypertension was associated with increased risk in both those with and without diabetes. CONCLUSIONS:Hypertension is associated with increased risk of posterior subcapsular opacities. The pathophysiologic mechanisms that may explain the relationship are unknown. Incidence data will give a better indication of temporal relationship between hypertension, medications to lower blood pressure, and lens opacities.

journal_name

Am J Ophthalmol

authors

Klein BE,Klein R,Jensen SC,Linton KL

doi

10.1016/s0002-9394(14)70223-5

subject

Has Abstract

pub_date

1995-05-01 00:00:00

pages

640-6

issue

5

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(14)70223-5

journal_volume

119

pub_type

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