Abstract：
PURPOSE:To identify the frequency of recently acquired vs chronic systemic Toxoplasma gondii infections in patients with ocular toxoplasmosis. METHODS:Serum samples from 22 patients with primary ocular toxoplasmosis (not from scars) and 42 patients with recurrent ocular toxoplasmosis were tested for the presence of anti-T. gondii IgM, IgG, and IgA antibodies and compared with samples from 24 patients with other causes of uveitis. Intraocular production of anti-T. gondii IgG and IgA, and the presence of T. gondii DNA was determined in patient s and control subjects from whom ocular fluid was available. RESULTS:Serologic evidence of recently acquired infection was found for 11 (50%) of 22 patients with primary ocular toxoplasmosis and for one (2%) of 42 with recurrent ocular toxoplasmosis. In the uveitis control group, anti-T. gondii IgM antibodies could be detected in two (8%) of 24 patients, but anti-T. gondii IgA antibodies were not detectable. Patients with primary ocular toxoplasmosis and serologic markers of recently acquired systemic infection were significantly older than those with chronic infection (P = .008). Intraocular production of anti-T. gondii IgG was more frequently noted in patients with recurrent than primary ocular toxoplasmosis (81% vs 41%; P < .001), but intraocular T. gondii DNA was more frequently found in patients with primary ocular toxoplasmosis than in those with recurrent ocular toxoplasmosis (37% vs 4%; P < .01). CONCLUSIONS:Primary ocular toxoplasmosis can be seen in either recently acquired or chronic T. gondii infection. Patients with ocular disease and recently acquired infection were older and more likely to have T. gondii DNA in intraocular fluids.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Ongkosuwito JV,Bosch-Driessen EH,Kijlstra A,Rothova Adoi
10.1016/s0002-9394(99)00266-4subject
Has Abstractpub_date
1999-10-01 00:00:00pages
407-12issue
4eissn
0002-9394issn
1879-1891pii
S0002939499002664journal_volume
128pub_type
杂志文章abstract：PURPOSE:To measure the changes in optic disk morphology after unilateral disk hemorrhage and to compare the changes between eyes. DESIGN:Observational case series. METHODS:Ten glaucoma patients who had a unilateral disk hemorrhage were enrolled. The baseline measurements obtained by Heidelberg Retina Tomograph (HRT) ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01791-9
更新日期：2002-12-01 00:00:00
abstract：:Lenses removed in 408 cataract operations were cultured for bacteria. Most (78%) lenses were sterile. Of the positive cultures, 48% were positive for Staphylococcus epidermidis and 15.4% for S. aureus. These findings reflect the flora of the normal preoperative conjunctiva, and the organisms most commonly implicated i...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)76805-9
更新日期：1978-08-01 00:00:00
abstract：PURPOSE:To evaluate clinically the efficacy of 3600 minimally invasive endoscopic surgery in patients with orbital intraconal tumors. DESIGN:Retrospective interventional case series. METHODS:A series of consecutive patients with orbital intraconal tumors were treated by minimally invasive surgery using an endonasal e...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.07.035
更新日期：2020-07-29 00:00:00
abstract：PURPOSE:To establish the medium-term repeatability of the iPad perimetry app Melbourne Rapid Fields (MRF) compared to Humphrey Field Analyzer (HFA) 24-2 SITA-standard and SITA-fast programs. DESIGN:Multicenter longitudinal observational clinical study. METHODS:Sixty patients (stable glaucoma/ocular hypertension/glauc...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2018.03.009
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To evaluate the postoperative status of the macula after vitreous surgery with internal limiting membrane removal for macular hole related retinal detachment in patients with severe myopia. DESIGN:Interventional case series. METHODS:We prospectively examined 10 eyes with retinal detachment associated with a m...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(03)00186-7
更新日期：2003-08-01 00:00:00
abstract：:A 59-year-old woman with no evidence of glaucoma developed secondary open-angle glaucoma after an intracapsular cataract extraction complicated by vitreous and iris incarceration. Histopathologic and scanning and electron microscopic studies of the enucleated eye 22 years later revealed extensive proliferation of iris...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(79)90520-8
更新日期：1979-09-01 00:00:00
abstract：PURPOSE:To compare the results of combined trabeculectomy and phacoemulsification surgery with intraocular lens implant by means of a one-site vs a two-site approach. METHODS:Glaucomatous patients with a coexisting cataract were randomly assigned to undergo either a one-site or two-site combined procedure. One-site su...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9394(99)80143-3
更新日期：1998-03-01 00:00:00
abstract：:To facilitate placing pars plana infusion ports, we modified the shaft of a piece of 10-gauge tubing or of a hypodermic needle by removing the beveled tip and Luer hub, passing the tubing through the inserter sleeve, and then reattaching the tubing to the Luer hub. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(78)90251-9
更新日期：1978-09-01 00:00:00
abstract：:Benign lateral rectus palsy developed in two adults, a 62-year-old man and a 56-year-old woman. Both were hospitalized because of headache and diplopia. Extensive laboratory and neurologic testing showed no abnormalities except leukopenia (the white blood cell count was 2,600 cells/mm3 in one patient and 3,100 cells/m...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(82)90254-9
更新日期：1982-10-01 00:00:00
abstract：PURPOSE:To identify whether and how outcomes of macular hole (MH) surgery are influenced by the extent of internal limiting membrane (ILM) peeling. DESIGN:Randomized clinical trial. METHODS:This study involved 65 eyes from 65 patients who underwent surgery for idiopathic MH. ILM was peeled with a radius of either 0.7...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ajo.2016.06.041
更新日期：2016-09-01 00:00:00
abstract：PURPOSE:To report a case of small cell carcinoma of the thymus metastatic to the orbit. METHODS:At age 37 years, a man who had been previously diagnosed and treated for small cell carcinoma of the thymus was initially examined for vertical diplopia and left proptosis. Computed tomographic scan disclosed a soft tissue ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)70836-0
更新日期：1997-09-01 00:00:00
abstract：PURPOSE:To determine the spectrum of conjunctival flora and the antibiotic susceptibility profiles of patients undergoing cataract surgery at a Midwestern university. DESIGN:Prospective in vitro laboratory investigation of a patient cohort. METHODS:Conjunctival cultures were obtained from patients undergoing cataract...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2012.06.024
更新日期：2013-01-01 00:00:00
abstract：:The pathogenesis of reversible cupping of the optic disk in congenital glaucoma was examined by two approaches. Human fetal, neonatal, and adult eyes were examined by histochemistry and electron microscopy to delineate the embryologic development of the optic nerve head. While the neural, glial, and vascular elements ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(77)90680-8
更新日期：1977-09-01 00:00:00
abstract：PURPOSE:To detect potential differences in the phenotypes between Western normal-tension glaucoma (NTG) and Korean NTG. DESIGN:A retrospective, cross-sectional study. METHODS:One hundred eighty-four NTG eyes of 71 patients of the Jules Stein Eye Institute, University of California, Los Angeles, and 113 patients of th...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2012.11.020
更新日期：2013-05-01 00:00:00
abstract：PURPOSE:To report an unusual case of hypovitaminosis A with bilateral papilledema and flecked retina that regressed after restoration of vitamin A deficiency. METHOD:Case report. A 27-year-old woman had undergone a biliopancreatic bypass for obesity in 1990. In 1995, she presented with bilateral xerophthalmia, bilater...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00011-7
更新日期：1998-05-01 00:00:00
abstract：PURPOSE:To compare silicone-hydrogel, poly(2-hydroxyethyl methacrylate) (pHEMA), and phosphorylcholine-coated (PC-C) contact lenses in terms of their susceptibility to biofilm formation by Staphylococcus epidermidis and Pseudomonas aeruginosa. DESIGN:Laboratory investigation. METHODS:Biofilm formation on colonized te...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.07.032
更新日期：2009-01-01 00:00:00
abstract：:A 46-year-old woman had a hemangioma of the zygoma, which was excised flush with the normal bony contour. To the best of our knowledge, this is the second such case reported. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74865-2
更新日期：1980-08-01 00:00:00
abstract：PURPOSE:To report the cotransmission of retinitis punctata albescens (RPA) and congenital sensorineural deafness. METHODS:Case reports of two siblings with nyctalopia and profound bilateral sensorineural deafness. RESULTS:The affected siblings, an 11-year-old female and a 7-year-old male, presented with decreased vis...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00060-4
更新日期：1999-08-01 00:00:00
abstract：PURPOSE:To assess the relative distribution in the cornea of amyloid and (beta)ig-h3 gene product in lattice corneal dystrophy type IIIA (LCD-IIIA). METHODS:Serial sections from the cornea of a patient with LCD-IIIA were subjected to either Congo red staining or immunohistochemistry employing an antibody to (beta)ig-h...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00360-2
更新日期：1999-04-01 00:00:00
abstract：:In 29 experiments, vascular autologous retina from the contralateral rabbit eye was implanted into corneal pockets in New Zealand white rabbits. The implants induced a neovascular growth of limbal vessels that anastomosed with the vessels of the implant in 15 of the cases. Implantation of vascular autologous iris, cho...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(80)90116-6
更新日期：1980-02-01 00:00:00
abstract：PURPOSE:To report a case of unilateral blindness after ipsilateral prophylactic transcranial optic canal decompression for fibrous dysplasia. METHODS:Case report. A 37-year-old woman with fibrous dysplasia underwent a prophylactic left optic canal decompression. Preoperatively, the left eye had a visual acuity of 20/2...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00118-4
更新日期：1998-09-01 00:00:00
abstract：PURPOSE:To present a quantitative analysis of pterygium and ocular sun exposure, a dose-response curve, and a discussion of the health-promotion implications of the findings. METHODS:A hospital-based, case-control study was conducted in Perth, Western Australia. Case subjects had surgical removal of a pterygium; contr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00161-0
更新日期：1999-09-01 00:00:00
abstract：:Exposure to organic isocyanates in the atmosphere of a polyurethane-foam-producing company resulted in microcystic corneal epithelial edema and conjunctival injection localized primarily in the palpebral fissure. The degree of microcystic edema and decreased visual acuity appeared to be related to location, length of ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75137-2
更新日期：1980-11-01 00:00:00
abstract：:A 21-year-old white woman had an apparently benign fibrous histiocytoma at the corneoscleral limbus. By histopathologic and ultrastructural studies, the tumor consisted of lipid-containing histiocytes and fibrocytic cells arranged in a storiform configuration with a collagenous interstitium. After an excision, the les...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/0002-9394(75)90391-8
更新日期：1975-10-01 00:00:00
abstract：PURPOSE:To evaluate the anatomic and visual outcomes in patients with initially closed macular holes after vitreoretinal surgery and with 1 to 7 years of follow-up. DESIGN:Retrospective, noncomparative, consecutive case series. METHODS:Eighty-seven consecutive eyes of 79 patients with previous closure of the macular ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.11.006
更新日期：2011-05-01 00:00:00
abstract：PURPOSE:To report the effect of repeated corneal swabbing in patients with microsporidial keratoconjunctivitis. DESIGN:Retrospective noncomparative case series. METHODS:Sixteen eyes of 14 healthy patients with microsporidial keratoconjunctivitis were diagnosed based on the detection of microsporidia in corneal scrapi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2012.06.002
更新日期：2012-12-01 00:00:00
abstract：PURPOSE:To comprehensively evaluate the effectiveness of different types of laser trabeculoplasty (LT) in the treatment of open-angle glaucoma. DESIGN:Systematic review and network meta-analysis. METHODS:Eligible randomized controlled trials (RCT) were identified by searching PubMed, EMBASE, Cochrane Library, SCOPUS,...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.ajo.2020.07.046
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:To compare polymerase chain reaction (PCR) results to presumptive clinical diagnosis in patients with vitritis. DESIGN:Retrospective review of PCR laboratory records from vitreous samples. METHODS:Fifty consecutive laboratory records of vitreous samples sent for PCR testing were reviewed. Three reviewers with...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.10.011
更新日期：2006-03-01 00:00:00
abstract：PURPOSE:To report donor-to-host transmission of Candida albicans after penetrating keratoplasty. DESIGN:Interventional case report. METHODS:A 15-year-old boy who underwent penetrating keratoplasty for keratoconus with donor tissue from a drowning victim developed keratitis and a lenticular abscess 26 days postoperati...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(02)01427-7
更新日期：2002-07-01 00:00:00
abstract：PURPOSE:To investigate the natural history of Stargardt disease (STGD1) using fixation location and fixation stability. DESIGN:Multicenter, international, prospective cohort study. METHODS:Fixation testing was performed using the Nidek MP-1 microperimeter as part of the prospective, multicenter, natural history study...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajo.2018.06.003
更新日期：2018-09-01 00:00:00
