Low prevalence of MODY2 and MODY3 mutations in Brazilian individuals with clinical MODY phenotype.

abstract：:Our aim was to see the levels of lipoprotein (a) (Lp (a)) in patients with gangrenous or non-gangrenous diabetic foot lesions. Twenty-two patients with gangrenous foot lesions, 11 with non-gangrenous foot lesions and 10 healthy subjects were included in the study. All the patients had similar glycemic control and dura...

journal_title：Diabetes research and clinical practice

authors： Unlühizarci K,Muhtaroğlu S,Kabak S,Bayram F,Keleştimur F

更新日期：2006-02-01 00:00:00

abstract：AIMS:To test whether the genetic variant CCR5Delta32 in the CC-chemokine receptor 5, which is known to lead to CCR5 deficiency, is associated with mortality in type 2 diabetes patients. METHODS:We examined the effect of presence or absence of the CCR5Delta32 on overall and cardiovascular mortality risk in the Zwolle O...

journal_title：Diabetes research and clinical practice

authors： Muntinghe FL,Gross S,Bakker SJ,Landman GW,van der Harst P,Bilo HJ,Navis G,Zuurman MW

更新日期：2009-11-01 00:00:00

abstract：:Analyses of direct effects of smoking on peripheral arteries were done using thermography, blood fluorometry and echography on 97 habitual smoker-diabetics without triopathy. There were found to be four types of thermographic changes following smoking, which varied according to the degree of atherosclerosis of the art...

journal_title：Diabetes research and clinical practice

authors： Fushimi H,Kubo M,Inoue T,Yamada Y,Matsuyama Y,Kameyama M

更新日期：1998-10-01 00:00:00

abstract：:Diabetes self management education, the process of teaching individuals to manage their diabetes, has been considered the cornerstone of the clinical management of individuals with diabetes since the work of the Joslin Diabetes Center. The goals of self-management education are to optimize metabolic control, prevent a...

journal_title：Diabetes research and clinical practice

authors： Benroubi M

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:The prevalence of treatment resistant hypertension (RH) depends on methods used for blood pressure (BP) measurements, goals of BP, and therapeutic efforts in terms of medication and adherence. We focused on diabetic subjects and explored the prevalence of RH in primary care practice. METHODS:In 1737 subjects...

journal_title：Diabetes research and clinical practice

authors： Yokoyama H,Araki S,Watanabe S,Honjo J,Okizaki S,Yamada D,Shudo R,Shimizu H,Sone H,Haneda M

更新日期：2015-10-01 00:00:00

abstract：:The prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) and their relationship to age and obesity was estimated in a population-based survey in urban and rural areas in Baluchistan province, Pakistan. Cluster sampling of 834 adults (260 men, 574 women) in the urban and 570 adults (175 men, 395 wo...

journal_title：Diabetes research and clinical practice

authors： Shera AS,Rafique G,Khawaja IA,Baqai S,King H

更新日期：1999-04-01 00:00:00

abstract：AIMS:To study HLA-DQB1 genes and islet cell autoantibodies against glutamic acid decarboxylase 65 (GADA) and insulinoma antigen-2 (IA-2A) in relation to diabetes post partum in mothers with diagnosed gestational diabetes mellitus (GDM). METHODS:During 2003-2004, women undergoing a 75 g oral glucose tolerance test (OGT...

journal_title：Diabetes research and clinical practice

authors： Papadopoulou A,Lynch KF,Anderberg E,Landin-Olsson M,Hansson I,Agardh CD,Lernmark Å,Berntorp K

更新日期：2012-02-01 00:00:00

abstract：:In November 1990, we carried out a survey of chronic complications of diabetes in more than 2000 diabetic patients who were seen on one day in 35 medical institutions including university hospitals, other hospitals and small clinics. More than 60% were aged 55-74 years. About 7% of patients had IDDM. Hypertension was ...

journal_title：Diabetes research and clinical practice

authors： Kuzuya T,Akanuma Y,Akazawa Y,Uehata T

更新日期：1994-10-01 00:00:00

abstract：AIMS:Evidence suggests that chronic hyperglycaemia predicts not only microvascular disease but also macrovascular disease, however it is not known whether it is the glucose variability per se or the total glucose exposure that confers risk. The objective of this study was to investigate whether daily glucose variabilit...

journal_title：Diabetes research and clinical practice

authors： Gordin D,Rönnback M,Forsblom C,Mäkinen V,Saraheimo M,Groop PH

更新日期：2008-06-01 00:00:00

abstract：INTRODUCTION:Diabetes is a serious and increasing global health burden and estimates of prevalence are essential for appropriate allocation of resources and monitoring of trends. METHODS:We conducted a literature search of studies reporting the age-specific prevalence for diabetes and used the Analytic Hierarchy Proce...

journal_title：Diabetes research and clinical practice

authors： Guariguata L,Whiting DR,Hambleton I,Beagley J,Linnenkamp U,Shaw JE

更新日期：2014-02-01 00:00:00

abstract：:As a westernized lifestyle becomes widespread in Japan, the number of individuals with obesity, as well as type 2 diabetes, is rapidly increasing. In this investigation, we studied the prevalence of obesity and its association with the development of diabetic macroangiopathy and microangiopathy. The clinical records o...

journal_title：Diabetes research and clinical practice

authors： Ogawa K,Ueda K,Sasaki H,Yamasaki H,Okamoto K,Wakasaki H,Matsumoto E,Furuta H,Hanabusa T,Nishi M,Nanjo K

更新日期：2004-12-01 00:00:00

abstract：AIMS:To compare the ability of definitions of Metabolic Syndrome (MetS) in the prediction of type 2 diabetes. METHODS:We examined 4756 subjects in an Iranian population who were non-diabetic at baseline. After 3.6 years, 188 individuals developed diabetes. RESULTS:Impaired glucose tolerance (IGT) and MetS definitions...

journal_title：Diabetes research and clinical practice

authors： Hadaegh F,Ghasemi A,Padyab M,Tohidi M,Azizi F

更新日期：2008-05-01 00:00:00

abstract：:We performed a retrospective pooled analysis of 28 patients who had been diagnosed with insulin autoimmune syndrome and evaluated the prevalence of anti-insulin receptor antibodies. Dual positivity for anti-insulin and anti-insulin receptor antibodies was common (53.8%). However, these patients had a similar phenotype...

journal_title：Diabetes research and clinical practice

authors： Kim SW,Won HK,Seok H,Lee BW,Jung CH,Lee WJ,Kim JH

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To compare the prevalence of the Metabolic Syndrome (MetS) defined by four definitions and to determine which definition best identifies those at high cardiovascular disease (CVD) risk and with insulin resistance. METHODS:AusDiab is a population-based survey of 11,247 Australians. Participants had anthropome...

journal_title：Diabetes research and clinical practice

authors： Cameron AJ,Magliano DJ,Zimmet PZ,Welborn T,Shaw JE

更新日期：2007-09-01 00:00:00

abstract：AIMS:The aim of this study is to investigate the association between metformin usage and dementia in an elderly Korean population. METHODS:Participants were divided into five groups: metformin non-users with diabetes mellitus (DM), metformin users with DM (low-, mid-, and high-users), and non-diabetic Individuals. Dem...

journal_title：Diabetes research and clinical practice

authors： Kim Y,Kim HS,Lee JW,Kim YS,You HS,Bae YJ,Lee HC,Han YE,Choi EA,Kim J,Kang HT

更新日期：2020-12-01 00:00:00

abstract：:Insulin resistance (IR) is postulated to underlie diabetes, the metabolic syndrome (MS) and cardiovascular disease (CVD). The D20S32e marker close to the melanocortin receptor-3 (hMC3-R) has been shown to be associated with IR in a large New Zealand Māori kindred, a population at high risk for MS and CVD. Here we exam...

journal_title：Diabetes research and clinical practice

authors： Wong J,Nock NL,Xu Z,Kyle C,Daniels A,White M,Yue DK,Elston RC,Mountjoy KG

更新日期：2008-05-01 00:00:00

abstract：:Amid the rapidly rising number of people with diabetes worldwide, the prevalence of diabetic kidney disease (DKD) is expected to increase considerably despite available treatments. Consequently, novel therapeutic agents are urgently needed. Ruboxistaurin mesylate is a bisindolylmaleimide that specifically inhibits the...

journal_title：Diabetes research and clinical practice

authors： Tuttle KR

更新日期：2008-11-13 00:00:00

abstract：:Recent studies have shown both association and linkage between a Gly40-Ser mutation in the glucagon receptor gene and NIDDM in French patients with familial NIDDM. This mutation was present in heterozygous form in 4.6% of diabetic probands but only 1% of the French population, suggesting that it was an important risk ...

journal_title：Diabetes research and clinical practice

authors： Ogata M,Iwasaki N,Ohgawara H,Karibe S,Omori Y

更新日期：1996-07-01 00:00:00

abstract：AIMS:Evidence suggests that screening for gestational diabetes (GDM) occurs too late in pregnancy, when changes in glucose metabolism and fetal growth rates can already be detected. In August 2016 NHS Lothian began screening women with risk factors for GDM during early pregnancy (11-13 weeks). We hypothesised that an e...

journal_title：Diabetes research and clinical practice

authors： Ryan DK,Haddow L,Ramaesh A,Kelly R,Johns EC,Denison FC,Dover AR,Reynolds RM

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:To evaluate the efficacy of continuous glucose monitoring system (CGMS) to detect postprandial hyperglycemia and unrecognized hypoglycemia in type 1 diabetes mellitus (DM1) patients. METHODS:We studied 46 patients (43.4%M/56.6%F), average age of 25.9+/-12.8 years, submitted to 72 h CGMS. It were analyzed: c...

journal_title：Diabetes research and clinical practice

authors： Maia FF,Araújo LR

更新日期：2007-01-01 00:00:00

abstract：AIMS:We tested the hypothesis that short sleep duration is not only a risk factor for diabetes, but that the two conditions in combination would be associated with the risk of incident cardiovascular disease (CVD). METHODS:We analyzed 1255 hypertensive patients (mean age: 70.4±9.9 years) with (N=299) and without diabe...

journal_title：Diabetes research and clinical practice

authors： Eguchi K,Hoshide S,Ishikawa S,Shimada K,Kario K

更新日期：2012-12-01 00:00:00

abstract：:Serum paraoxonase (PON) is a high-density lipoprotein-bound enzyme that can prevent oxidation of low-density lipoprotein by hydrolyzing lipid peroxides and thus exert an anti-atherogenic effect. Recent studies have suggested that glutamine(Q isoform)/arginine(R isoform) polymorphism at position 192 of PON(1) gene is a...

journal_title：Diabetes research and clinical practice

authors： Hu Y,Tian H,Liu R

更新日期：2003-07-01 00:00:00

abstract：:With the objective to determine the frequency of microalbuminuria, macroalbuminuria and the associated clinic and metabolic features among insulin dependent diabetes mellitus (IDDM) Brazilian patients attending at a general University Hospital, a total of 50 outpatients, aged 21.9 +/- 7 years with IDDM duration of 6.8...

journal_title：Diabetes research and clinical practice

authors： Gomes MB,Lucchetti MR,Gazzola H,Dimetz T,Gonçalves MF,Neves R,Matos H

更新日期：1997-03-01 00:00:00

abstract：:We have quantitatively assessed the percentage of lower limb arterio-venous (a-v) shunting using a radioisotopic technique and correlated it with autonomic neuropathy evaluated by cardiovascular tests. We have studied three groups of diabetic patients: Group A, 12 non-neuropathic subjects without foot lesions; Group B...

journal_title：Diabetes research and clinical practice

authors： Uccioli L,Mancini L,Giordano A,Solini A,Magnani P,Manto A,Cotroneo P,Greco AV,Ghirlanda G

更新日期：1992-05-01 00:00:00

abstract：AIMS:Vitamin K-dependent growth arrest-specific protein 6 (Gas6) and its receptors of the TAM (TYRO-3/Axl/Mer) family are ubiquitously expressed in immune, cardiovascular, and reproductive systems. They play pivotal roles of regulating tissue homeostasis via anti-inflammatory effects. Recent studies show that the Gas6/...

journal_title：Diabetes research and clinical practice

authors： Kuo FC,Hung YJ,Shieh YS,Hsieh CH,Hsiao FC,Lee CH

更新日期：2014-02-01 00:00:00

abstract：AIM:The aim of this study was to assess the vaspin and adiponectin concentrations on markers of insulin sensitivity and obesity in pubertal obese children and adolescents. MATERIAL AND METHODS:Plasma vaspin and adiponectin level and its relationships with body mass index standard deviation score (BMI-SDS), insulin sen...

journal_title：Diabetes research and clinical practice

authors： Suleymanoglu S,Tascilar E,Pirgon O,Tapan S,Meral C,Abaci A

更新日期：2009-06-01 00:00:00

abstract：:The glycemic response following ingestion of carbohydrate in various forms is different. The factors involved are not fully elucidated. In this study the glycemic and insulin responses to 50 g of carbohydrate in the form of white bread (WB), semolina bread (SB), white spaghetti (WS) and wholemeal spaghetti (BS) were c...

journal_title：Diabetes research and clinical practice

authors： d'Emden MC,Marwick TH,Dreghorn J,Howlett VL,Cameron DP

更新日期：1987-07-01 00:00:00

abstract：AIM:The aim of this study was to examine the association of serum bilirubin, an endogenous antioxidant, with serum high sensitivity C-reactive protein (hs-CRP) level, HbA(1c), and the prevalence of type 2 diabetes in middle-aged and elderly Japanese men and women (n=12,400). METHODS:Analysis of covariance and logistic...

journal_title：Diabetes research and clinical practice

authors： Ohnaka K,Kono S,Inoguchi T,Yin G,Morita M,Adachi M,Kawate H,Takayanagi R

更新日期：2010-04-01 00:00:00

abstract：AIM:To evaluate the relationship of plasma endothelin-1 (ET-1) levels, a marker of endothelial dysfunction, and urinary albumin excretion in patients with type 2 diabetes mellitus (DM). METHODS:Cross-sectional study was conducted in 279 patients (132 males, mean age: 58.7+/-11.0 years, mean DM duration: 11.3+/-8.1 yea...

journal_title：Diabetes research and clinical practice

authors： Zanatta CM,Gerchman F,Burttet L,Nabinger G,Jacques-Silva MC,Canani LH,Gross JL

更新日期：2008-05-01 00:00:00

abstract：AIMS:Pulmonary infections are more frequent in and associated with higher mortality in Cystic Fibrosis-Related Diabetes (CFRD) patients compared to CF patients without CFRD. Hyperglycaemia can lead to a higher vulnerability for infections. Aim of the study was to test whether the infection rate in well-controlled CFRD ...

journal_title：Diabetes research and clinical practice

authors： Belle-van Meerkerk G,de Valk HW,Stam-Slob MC,Teding van Berkhout F,Zanen P,van de Graaf EA

更新日期：2016-06-01 00:00:00