Fear, guilt feelings and misconceptions: barriers to effective insulin treatment in type 2 diabetes.

Abstract:

:Diabetes self management education, the process of teaching individuals to manage their diabetes, has been considered the cornerstone of the clinical management of individuals with diabetes since the work of the Joslin Diabetes Center. The goals of self-management education are to optimize metabolic control, prevent acute and chronic complications, and optimize quality of life. The keystone to successful management is to involve the patient in his treatment. Clearly, factors other than knowledge and effective therapies affect the behaviors of patients and health care professionals and influence their ability to make optimal use of available treatments. The DAWN study has shown that both health care providers and patients may have a negative attitude toward starting insulin therapy. Patients with type 2 diabetes are very often reluctant to accept insulin therapy. The reasons most commonly encountered, for this negative attitude are: Patients blame themselves, for they consider that starting insulin therapy would indicate they had "failed" proper diabetes self-management. For some patients taking insulin means life will be more restricted or it means they have reached their last resort. Fear of hypoglycemia is a very common barrier for insulin therapy. Physicians may, unconsciously, negatively influence their patients. For some physicians putting his patient on insulin, means that he has failed to control his patient's diabetes on oral agents and now has to force him in a troublesome therapeutic regime. In order to overcome these barriers, health care professionals, rather than trying to "convince" their patients of the necessity of the treatment, should assess, by active listening, the precise reason for which his/her patient denies it.

authors

Benroubi M

doi

10.1016/S0168-8227(11)70021-3

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

S97-9

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(11)70021-3

journal_volume

93 Suppl 1

pub_type

杂志文章,评审
  • Effects of prediabetes on long-term clinical outcomes of patients with acute myocardial infarction who underwent PCI using new-generation drug-eluting stents.

    abstract:AIMS:We investigated the 2-year clinical outcomes of patients with acute myocardial infarction (AMI) and prediabetes after new-generation drug-eluting stents implantation. METHODS:A total of 11,962 patients with AMI were classified into normoglycemia (group A; 3,080), prediabetes (group B; 3,709), and diabetes (group ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.diabres.2019.107994

    authors: Kim YH,Her AY,Jeong MH,Kim BK,Hong SJ,Kim S,Ahn CM,Kim JS,Ko YG,Choi D,Hong MK,Jang Y

    更新日期:2020-02-01 00:00:00

  • Weight stigma and diabetes stigma in U.S. adults with type 2 diabetes: Associations with diabetes self-care behaviors and perceptions of health care.

    abstract:AIMS:Diabetes stigma and weight stigma have been identified as important but neglected issues that warrant attention among people with type 2 diabetes. This study assessed associations of diabetes stigma and weight stigma with diabetes self-care behaviors and health care in adults with type 2 diabetes. METHODS:U.S. ad...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2020.108387

    authors: Puhl RM,Himmelstein MS,Hateley-Browne JL,Speight J

    更新日期:2020-10-01 00:00:00

  • One-year effects of a group-based lifestyle intervention in adults with type 2 diabetes: A randomized encouragement trial.

    abstract:AIMS:To estimate the real-world effects of offering a group-based lifestyle intervention (GLI) to adults with diabetes. METHODS:This randomized encouragement trial included adult primary care patients in metropolitan Chicago with type 2 diabetes and body mass index ≥24 kg/m2. Participants were randomized to standard c...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.diabres.2018.03.030

    authors: Liss DT,Finch EA,Cooper A,Sheth A,Tejuosho AD,Lancki N,Ackermann RT

    更新日期:2018-06-01 00:00:00

  • Insulin requirement profiles of short-term intensive insulin therapy in patients with newly diagnosed type 2 diabetes and its association with long-term glycemic remission.

    abstract:AIMS:To investigate the insulin requirement profiles during short-term intensive continuous subcutaneous insulin infusion (CSII) in patients with newly diagnosed type 2 diabetes and its relationship with long-term glycemic remission. METHODS:CSII was applied in 104 patients with newly diagnosed type 2 diabetes. Daily ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.diabres.2015.02.011

    authors: Liu L,Ke W,Wan X,Zhang P,Cao X,Deng W,Li Y

    更新日期:2015-05-01 00:00:00

  • Importance of hypercoagulability over hyperglycemia for vascular complication in type 2 diabetes.

    abstract::To critically evaluate the relative importance of coagulation abnormalities over other clinical variables for micro- and macrovascular diabetic complications, prothrombin fragment (F1+2), thrombin-antithrombin III complex (TAT), fibrin degradation product d-dimer, and alpha2 plasmin inhibitor complex were determined i...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(00)00134-0

    authors: Yamada T,Sato A,Nishimori T,Mitsuhashi T,Terao A,Sagai H,Komatsu M,Aizawa T,Hashizume K

    更新日期:2000-07-01 00:00:00

  • Impaired fasting plasma glucose is a risk indicator of interventricular septum thickening among non-diabetic subjects with obesity.

    abstract:AIMS:To evaluate whether progressively higher fasting plasma glucose (FPG) is associated to thickening of the interventricular septum (IVS) among non-diabetic subjects with obesity. METHODOLOGY:We studied 227 consecutive non diabetic patients (155 women and 72 men, age range 18-72 years) with overweight or obesity (BM...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2020.108436

    authors: Zupo R,Castellana F,Sardone R,Scicchitano P,Lampignano L,Ciccone MM,Triggiani V,Guastamacchia E,Giannelli G,De Pergola G

    更新日期:2020-11-01 00:00:00

  • The metabolic syndrome in Australia: prevalence using four definitions.

    abstract:OBJECTIVE:To compare the prevalence of the Metabolic Syndrome (MetS) defined by four definitions and to determine which definition best identifies those at high cardiovascular disease (CVD) risk and with insulin resistance. METHODS:AusDiab is a population-based survey of 11,247 Australians. Participants had anthropome...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2007.02.002

    authors: Cameron AJ,Magliano DJ,Zimmet PZ,Welborn T,Shaw JE

    更新日期:2007-09-01 00:00:00

  • Relationships of apolipoprotein B(100) with the metabolic syndrome in Type 2 diabetes mellitus.

    abstract::The current study assessed whether features of the metabolic syndrome are associated with higher apolipoprotein B(100) (apoB(100)) levels in people with Type 2 diabetes (n = 298) not taking lipid-lowering drugs. Body-mass index (BMI), waist:hip ratio (WHR), urinary albumin excretion rate, presence or absence of hypert...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(02)00096-7

    authors: Relimpio F,Losada F,Pumar A,Mangas MA,Morales F,Astorga R

    更新日期:2002-09-01 00:00:00

  • SGLT2 inhibitors with cardiovascular benefits: Transforming clinical care in Type 2 diabetes mellitus.

    abstract::Cardiovascular risk reduction in individuals with Type 2 diabetes mellitus (T2DM) is a key part of clinical management. Sodium-glucose co-transporter (SGLT2) inhibitors improve glycaemic control, reduce body weight and decrease blood pressure. In addition, the SGLT2 inhibitors empagliflozin and canagliflozin reduced t...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabres.2017.11.023

    authors: d'Emden M,Amerena J,Deed G,Pollock C,Cooper ME

    更新日期:2018-02-01 00:00:00

  • Intermediate-density lipoproteins, diabetes and coronary artery disease.

    abstract::The results of various studies suggest that hypertriglyceridaemia is associated with an increased risk of coronary artery disease. It is unclear, however, which particular triglyceride (TG)-rich lipoproteins contribute to the risk. Different types of TG-rich lipoprotein differ in function, composition, size and densit...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/s0168-8227(98)00040-0

    authors: Steiner G

    更新日期:1998-07-01 00:00:00

  • Lower limb arterio-venous shunts, autonomic neuropathy and diabetic foot.

    abstract::We have quantitatively assessed the percentage of lower limb arterio-venous (a-v) shunting using a radioisotopic technique and correlated it with autonomic neuropathy evaluated by cardiovascular tests. We have studied three groups of diabetic patients: Group A, 12 non-neuropathic subjects without foot lesions; Group B...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(92)90083-4

    authors: Uccioli L,Mancini L,Giordano A,Solini A,Magnani P,Manto A,Cotroneo P,Greco AV,Ghirlanda G

    更新日期:1992-05-01 00:00:00

  • Association of the DDAH2 gene polymorphism with type 2 diabetes and hypertension.

    abstract:AIMS:The aim of this study was to investigate whether the polymorphism of DDAH2 is associated with type 2 diabetes and hypertension in Korean population. METHODS:Total 605 subjects were included in this study: 403 patients with type 2 diabetes and 202 non-diabetic control subjects. The SNP rs805304 and rs2272592 in DD...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2012.04.015

    authors: Seo HA,Kim SW,Jeon EJ,Jeong JY,Moon SS,Lee WK,Kim JG,Lee IK,Park KG

    更新日期:2012-10-01 00:00:00

  • The impact of COVID-19 on people with diabetes in Brazil.

    abstract::The present study aims at identifying main barriers faced by people living with diabetes in Brazil during the COVID-19 pandemic. METHODS:In a convenience sampling study, data were collected from 1701 individuals, aged 18 or above; 75.54% female participants; 60.73% T1D and 30.75% T2D, between April 22nd and May 4th, ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2020.108304

    authors: Barone MTU,Harnik SB,de Luca PV,Lima BLS,Wieselberg RJP,Ngongo B,Pedrosa HC,Pimazoni-Netto A,Franco DR,Marinho de Souza MF,Malta DC,Giampaoli V

    更新日期:2020-08-01 00:00:00

  • The prognostic value of albuminuria for the development of cardiovascular disease and retinopathy: a 5-year follow-up of 451 patients with type 2 diabetes mellitus.

    abstract::The aim of the present study was to evaluate the risk for vascular morbidity or death and retinopathy in relation to urinary albumin concentration. To that end, we performed a 5-year follow-up study of all type 2 diabetic patients attending the outpatient-clinic. A total of 444 (98.4%) out of 451 adult patients initia...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(96)01218-1

    authors: Agardh CD,Agardh E,Torffvit O

    更新日期:1996-04-01 00:00:00

  • Association of VKORC1 -1639 G>A polymorphism with carotid intima-media thickness in type 2 diabetes mellitus.

    abstract:AIMS:Media calcification is a predictor of cardiovascular mortality in type 2 diabetes mellitus (T2DM). Undercarboxylation of some vitamin K-dependent proteins, due to genetic polymorphisms of VKORC1, can lead to calcification. We examined a potential association between VKORC1 -1639 G>A polymorphism and T2DM and, also...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2011.06.021

    authors: Tavridou A,Petridis I,Vasileiadis M,Ragia G,Heliopoulos I,Vargemezis V,Manolopoulos VG

    更新日期:2011-11-01 00:00:00

  • Rye products in the diabetic diet. Postprandial glucose and hormonal responses in non-insulin-dependent diabetic patients as compared to starch availability in vitro and experiments in rats.

    abstract::Rye flakes, rye bread and white wheat bread were given as suspensions to rats and in standardized breakfast meals to non-insulin-dependent diabetics. In both cases the postprandial glucose response was lower after rye bread than after wheat bread. A larger amount of starch remained in the stomach of the rats 15 min af...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(87)80012-8

    authors: Hagander B,Björck I,Asp NG,Efendić S,Holm J,Nilsson-Ehle P,Lundquist I,Scherstén B

    更新日期:1987-03-01 00:00:00

  • Insulin administration may trigger pancreatic beta-cell destruction in patients with type 2 diabetes.

    abstract::Insulin administration causes various types of immune response to insulin. However, there have been no reports that insulin administration triggers pancreatic beta-cell destruction in diabetic patients. We evaluated three patients who had suffered from type 2 diabetes or impaired glucose tolerance for 5-30 years. Afte...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2007.08.031

    authors: Nakamura M,Nishida W,Yamada Y,Chujo D,Watanabe Y,Imagawa A,Hanafusa T,Kawasaki E,Onuma H,Osawa H,Makino H

    更新日期:2008-02-01 00:00:00

  • Lipid peroxidation in type 2 normolipidemic diabetic patients.

    abstract::Vascular complications, as a consequence of atherosclerosis, are the main causes of morbidity and mortality in diabetes. Low density lipoprotein (LDL) oxidation is accepted as a relevant pathogenic mechanism in atherogenesis. The aim of this work was to study the relationship between lipid peroxidation (LPO) and metab...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(97)00032-6

    authors: Freitas JP,Filipe PM,Rodrigo FG

    更新日期:1997-05-01 00:00:00

  • Screening for HbA1c-defined prediabetes and diabetes in an at-risk greek population: performance comparison of random capillary glucose, the ADA diabetes risk test and skin fluorescence spectroscopy.

    abstract:BACKGROUND:We examined the accuracy of random capillary glucose (RCG) and two noninvasive screening methods, the ADA diabetes risk test (DRT) and skin fluorescence spectroscopy (SFS) as measured by Scout DS for detecting HbA1c-defined dysglycemia or type 2 diabetes in an at-risk cohort. METHODS:Subjects were recruited...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.diabres.2013.01.002

    authors: Tentolouris N,Lathouris P,Lontou S,Tzemos K,Maynard J

    更新日期:2013-04-01 00:00:00

  • Trends in utilization and outcomes of bariatric surgery in obese people with and without type 2 diabetes in Spain (2001-2010).

    abstract:AIM:Bariatric surgery is associated with a significant improvement in glucose control and even diabetes remission. There are no studies investigating national trends in the use of bariatric surgery in people with type 2 diabetes. We examine trends in the use of bariatric surgery in patients with and without type 2 diab...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2012.12.011

    authors: Lopez-de-Andres A,Jiménez-García R,Hernández-Barrera V,Gil-de-Miguel A,Jiménez-Trujillo MI,Carrasco-Garrido P

    更新日期:2013-03-01 00:00:00

  • To explore the association of Ramadan fasting with symptoms of depression, anxiety, and stress in people with diabetes.

    abstract:AIM:To explore the association of Ramadan fasting with symptoms of depression, anxiety, and stress in people with diabetes. METHODS:This observational study was conducted at Baqai Institute of Diabetology and Endocrinology between May-July 2017. Informed consent was taken from each study participant. Demographic and b...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2020.108545

    authors: Yousuf S,Syed A,Ahmedani MY

    更新日期:2020-11-21 00:00:00

  • Diabetes-related renal growth and IGF-I accumulation in castrated rats.

    abstract::The effects of castration on diabetes-related renal growth and IGF-I regulation were studied. In the rat, prepubertal castration is associated with a normal or increased surge in plasma insulin-like growth factor I (IGF-I) at the time of 'puberty'. In order to determine the role of sex steroids in the development of d...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(91)90048-i

    authors: Bach LA,Cox AJ,Jerums G

    更新日期:1991-10-01 00:00:00

  • The prevalence of 6 weeks postpartum abnormal glucose tolerance in Caucasian women with gestational diabetes.

    abstract:AIMS:To evaluate the incidence of impaired glucose tolerance (IGT), impaired fasting glucose (IFG) and diabetes in 318 Caucasian women with gestational diabetes (GDM) at 6 weeks postpartum. METHODS:All women had 75g OGTT and the following data were collected: age, height, weight, results of the challenge 50g and diagn...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2009.04.003

    authors: Ogonowski J,Miazgowski T

    更新日期:2009-06-01 00:00:00

  • Metabolic response 4 years after gastric bypass in a complete cohort with type 2 diabetes mellitus.

    abstract:AIMS:To evaluate the long-term remission rates of type 2 diabetes mellitus and associated comorbidities after gastric bypass surgery in a complete cohort, in a real-life clinic setting. METHODS:A retrospective study of all consecutive patients with type 2 diabetes mellitus who underwent gastric bypass at a Veterans Af...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2017.11.022

    authors: Carranza-Leon BG,Puzziferri N,Adams-Huet B,Jabbour I,Lingvay I

    更新日期:2018-03-01 00:00:00

  • Function of hormone-sensitive lipase in diacylglycerol-protein kinase C pathway.

    abstract::To explore the functional effects of hormone-sensitive lipase (HSL) in diacylglycerol (DAG) metabolism, Chinese hamster ovary cells were stably transfected with rat HSL cDNA (wt-HSL), inactive mutant S423A-HSL cDNA (S423A) and pcDNA3 vector alone (Ct). [(14)C]Glucose-incorporation into triglyceride (TG) was 75% lower ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2004.02.006

    authors: Kanehara H,Suzuki J,Zenimaru Y,Takahashi S,Oida K,Shen WJ,Kraemer FB,Miyamori I

    更新日期:2004-09-01 00:00:00

  • An immunopotentiator of beta-1,6;1,3 D-glucan prevents diabetes and insulitis in BB rats.

    abstract::The preventive effect of an immunopotentiator, beta-1,6;1,3 D-glucan, on the development of diabetes and insulitis was studied in BB rats. The intravenous administration of 1 mg kg-1 week-1 of beta-1,6;1,3 D-glucan from the age of 4 weeks decreased the cumulative incidence of diabetes from 43.3% (13/30) to 6.7% (2/30)...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(92)90152-h

    authors: Kida K,Inoue T,Kaino Y,Goto Y,Ikeuchi M,Ito T,Matsuda H,Elliott RB

    更新日期:1992-08-01 00:00:00

  • Genetic markers of immunoglobulins and diabetes mellitus in the multiracial population of New Caledonia. The CALDIA Study Group.

    abstract::GM and KM immunoglobulin allotypes, which are the markers, respectively, of the constant parts of the heavy and the light chains of the IgG1, IgG2 and IgG3 subclasses, have been analysed in diabetic mellitus patients and controls living in New Caledonia. We tested 40 Europeans, 256 Melanesians and 44 Polynesians, as w...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(99)00125-4

    authors: Dugoujon JM,Guitard E,Sénégas MT,Roth MP,Sanchez A,Barny S,Simon D,Papoz L

    更新日期:2000-03-01 00:00:00

  • Prevalence, age at diagnosis, clinical characteristics and treatment of diabetes in the young in Pahang, Malaysia.

    abstract::The prevalence, age at diagnosis, clinical characteristics and treatment of young diabetics, younger than 40 years were determined on the basis of a cross-sectional study of medical records of 2 health districts in Pahang, Malaysia. There were only 20 insulin-dependent diabetics (IDDM), prevalence 0.07 per 1000 inhabi...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(91)90078-r

    authors: Lim TO

    更新日期:1991-07-01 00:00:00

  • Triple therapy combinations for the treatment of type 2 diabetes - A network meta-analysis.

    abstract:AIM:To estimate and compare the results from all randomised trials of triple combinations of anti-diabetes therapies that reported the reduction of glycated haemoglobin (HbA1c) and associated effects on body weight and hypoglycaemia. METHODS:PubMed and the Cochrane Library were searched for trials with at least one st...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.diabres.2016.04.037

    authors: Lee CM,Woodward M,Colagiuri S

    更新日期:2016-06-01 00:00:00

  • Prevalence of diabetes and prediabetes in tribal population of Kashmir: Lessons for the future.

    abstract:AIMS:Considering a surge in the incidence of Diabetes mellitus (DM) across all ethnic groups and lack of any representative data from the tribal communities of Jammu and Kashmir, the present study aimed to assess the prevalence of DM and prediabetes in them. METHODS:Subjects were recruited from five districts of Kashm...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2020.108457

    authors: Ganie MA,Sahar T,Rashid A,Baba MS,Ahmad N,Bhat H,Wani IA,Shah ZA

    更新日期:2020-11-01 00:00:00