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The metabolic syndrome in Australia: prevalence using four definitions.

Abstract：

OBJECTIVE:To compare the prevalence of the Metabolic Syndrome (MetS) defined by four definitions and to determine which definition best identifies those at high cardiovascular disease (CVD) risk and with insulin resistance. METHODS:AusDiab is a population-based survey of 11,247 Australians. Participants had anthropometry, blood pressure, and fasting biochemistry. Ten-year CVD risk was calculated. RESULTS:The prevalence of the MetS using the ATPIII, WHO, IDF, and EGIR definitions was 22.1% (95%Cl: 18.8, 25.4), 21.7% (19.0, 24.3), 30.7% (27.1, 34.3), and 13.4% (11.8, 14.9), respectively. Comparing those with to those without the MetS, the odds ratios (95%CI) for having a 10 year CVD risk > or =15% were 6.6 (5.4, 8.2), 5.5 (4.7, 6.5), 5.6 (4.8, 6.6), and 3.5 (3.0, 4.1), for the WHO, ATPIII, IDF, and EGIR definitions, respectively. The population attributable risk (PAR) of high CVD risk due to the MetS was highest for the IDF (23.4%). Insulin resistance was detected in 56.1, 69.7, 50.9, and 91.1% of those meeting the ATPIII, WHO, IDF, and EGIR definitions, respectively. CONCLUSION:The WHO definition was associated with the greatest CVD risk, but is not practical for clinical use. The higher PAR due to the IDF definition, with only slightly lower CVD risk than WHO, and clinical utility of the IDF definition, indicates that it may be a useful tool for CVD prevention.

journal_name

Diabetes Res Clin Pract

journal_title

Diabetes research and clinical practice

authors

Cameron AJ,Magliano DJ,Zimmet PZ,Welborn T,Shaw JE

doi

10.1016/j.diabres.2007.02.002

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

471-8

issue

3

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(07)00107-6

journal_volume

77

pub_type

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