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Serum BAFF expression in patients with myasthenia gravis.

Abstract：

:A B-cell activating factor of the tumor necrosis factor (TNF) family (BAFF) is an essential B-cell survival factor. Myasthenia gravis (MG) is one of the most typical antibody-mediated autoimmune disorders. To test whether serum BAFF levels are increased in MG patients, we compared the serum BAFF levels of 40 MG patients with those of 30 healthy controls. Serum BAFF levels of MG group were significantly higher than those of healthy group. These results suggested that the BAFF might play a role in the immunopathogenesis of MG and further study on B-cell and T-cell activation may be needed.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Kim JY,Yang Y,Moon JS,Lee EY,So SH,Lee HS,Park KD,Choi YC

doi

10.1016/j.jneuroim.2008.05.010

subject

Has Abstract

pub_date

2008-08-13 00:00:00

pages

151-4

issue

1-2

eissn

0165-5728

issn

1872-8421

pii

S0165-5728(08)00174-4

journal_volume

199

pub_type

杂志文章

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