Abstract：
:The hippocampus is thought to be involved in episodic memory formation by reactivating traces of waking experience during sleep. Indeed, the joint firing of spatially tuned pyramidal cells encoding nearby places recur during sleep. We found that the sleep cofiring of rat CA1 pyramidal cells encoding similar places increased relative to the sleep session before exploration. This cofiring increase depended on the number of times that cells fired together with short latencies (<50 ms) during exploration, and was strongest between cells representing the most visited places. This is indicative of a Hebbian learning rule in which changes in firing associations between cells are determined by the number of waking coincident firing events. In contrast, cells encoding different locations reduced their cofiring in proportion to the number of times that they fired independently. Together these data indicate that reactivated patterns are shaped by both positive and negative changes in cofiring, which are determined by recent behavior.
journal_name
Nat Neuroscijournal_title
Nature neuroscienceauthors
O'Neill J,Senior TJ,Allen K,Huxter JR,Csicsvari Jdoi
10.1038/nn2037subject
Has Abstractpub_date
2008-02-01 00:00:00pages
209-15issue
2eissn
1097-6256issn
1546-1726pii
nn2037journal_volume
11pub_type
杂志文章abstract：:We report on two brain-damaged subjects who exhibit the uncommon pattern of loss of object color knowledge, but spared color perception and naming. The subject P.C.O., as in previously reported patients, is also impaired in processing other perceptual and functional properties of objects. I.O.C., in contrast, is the f...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/88497
更新日期：2001-06-01 00:00:00
abstract：:Understanding a sensory system implies the ability to predict responses to a variety of inputs from a common model. In the retina, this includes predicting how the integration of signals across visual space shapes the outputs of retinal ganglion cells. Existing models of this process generalize poorly to predict respo...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.3225
更新日期：2012-11-01 00:00:00
abstract：:We introduce a deceptively simple behavioral task that robustly identifies two qualitatively different groups within the general population. When presented with an isochronous train of random syllables, some listeners are compelled to align their own concurrent syllable production with the perceived rate, whereas othe...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/s41593-019-0353-z
更新日期：2019-04-01 00:00:00
abstract：:In the postnatal subventricular zone (SVZ), local cues or signaling molecules released from neuroblasts limit the proliferation of glial fibrillary acidic protein (GFAP)-expressing progenitors thought to be stem cells. However, signals between SVZ cells have not been identified. We show that depolarization of neurobla...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn1522
更新日期：2005-09-01 00:00:00
abstract：:Accurate optical reporting of electrical activity in genetically defined neuronal populations is a long-standing goal in neuroscience. We developed Accelerated Sensor of Action Potentials 1 (ASAP1), a voltage sensor design in which a circularly permuted green fluorescent protein is inserted in an extracellular loop of...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.3709
更新日期：2014-06-01 00:00:00
abstract：:The identification of distinct cell types in the basal ganglia has been critical to our understanding of basal ganglia function and the treatment of neurological disorders. The external globus pallidus (GPe) is a key contributor to motor suppressing pathways in the basal ganglia, yet its neuronal heterogeneity has rem...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.4559
更新日期：2017-06-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章,评审
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更新日期：2013-07-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn1559
更新日期：2005-11-01 00:00:00
abstract：:Ongoing sensory input is critical for shaping internal representations of the external world. Conversely, a lack of sensory input can profoundly perturb the formation of these representations. The olfactory system is particularly vulnerable to sensory deprivation, owing to the widespread prevalence of allergic, viral ...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.3186
更新日期：2012-09-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.4374
更新日期：2016-10-01 00:00:00
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journal_title：Nature neuroscience
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更新日期：1999-05-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章,评审
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更新日期：2017-12-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/s41593-019-0427-y
更新日期：2019-08-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn1134
更新日期：2003-11-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章,评审
doi：10.1038/nn.3604
更新日期：2014-03-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/2232
更新日期：1998-10-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn1023
更新日期：2003-04-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.3348
更新日期：2013-04-01 00:00:00
abstract：:Previous gene knockout studies have shown that the orphan glutamate receptor delta2 (GluRdelta2) is critically involved in synaptogenesis between parallel fibers and Purkinje cells during development. However, the precise function of GluRdelta2 and whether it is functional in the mature cerebellum remain unclear. To a...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn1086
更新日期：2003-08-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn1898
更新日期：2007-05-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn1407
更新日期：2005-03-01 00:00:00
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pub_type： 杂志文章
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更新日期：2000-05-01 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
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pub_type： 已发布勘误
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更新日期：2019-12-01 00:00:00
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更新日期：2002-12-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.3729
更新日期：2014-07-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
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更新日期：2004-08-01 00:00:00
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更新日期：2006-08-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.3960
更新日期：2015-04-01 00:00:00
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更新日期：2004-09-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
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更新日期：2007-12-01 00:00:00
